DK0815255T3 - Phosphoglycan-mimetika af hormoner og vækstfaktorer fra Mycobacterium vaccae - Google Patents

Phosphoglycan-mimetika af hormoner og vækstfaktorer fra Mycobacterium vaccae

Info

Publication number: DK0815255T3
Authority: DK; Denmark
Prior art keywords: pct; messenger; mimetic; sec; phosphoglycan
Prior art date: 1995-03-21

Application number

DK96907595T

Other languages

English (en)

Inventor

T W University Col Rademacher

H N University Col London Caro

G A W University Col Lond Rook

Original Assignee

Innopeg Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-21

Filing date

1996-03-20

Publication date

2003-09-15

1996-03-20 Application filed by Innopeg Ltd filed Critical Innopeg Ltd

2003-09-15 Application granted granted Critical

2003-09-15 Publication of DK0815255T3 publication Critical patent/DK0815255T3/da

Links

241000187644 Mycobacterium vaccae Species 0.000 title abstract 2
239000003102 growth factor Substances 0.000 title abstract 2
229940088597 hormone Drugs 0.000 title abstract 2
239000005556 hormone Substances 0.000 title abstract 2
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
SUHQNCLNRUAGOO-KQCZLNONSA-N (4s,5r,6r,7s,8r)-4,6,7,8,9-pentahydroxy-5-[(2-hydroxyacetyl)amino]-2-oxononanoic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](NC(=O)CO)[C@@H](O)CC(=O)C(O)=O SUHQNCLNRUAGOO-KQCZLNONSA-N 0.000 abstract 1
206010001324 Adrenal atrophy Diseases 0.000 abstract 1
208000007848 Alcoholism Diseases 0.000 abstract 1
239000000055 Corticotropin-Releasing Hormone Substances 0.000 abstract 1
ZWQVYZXPYSYPJD-RYUDHWBXSA-N Glu-Gly-Phe Chemical compound OC(=O)CC[C@H](N)C(=O)NCC(=O)N[C@H](C(O)=O)CC1=CC=CC=C1 ZWQVYZXPYSYPJD-RYUDHWBXSA-N 0.000 abstract 1
102000004877 Insulin Human genes 0.000 abstract 1
108090001061 Insulin Proteins 0.000 abstract 1
206010067125 Liver injury Diseases 0.000 abstract 1
241000186359 Mycobacterium Species 0.000 abstract 1
206010067584 Type 1 diabetes mellitus Diseases 0.000 abstract 1
206010001584 alcohol abuse Diseases 0.000 abstract 1
208000025746 alcohol use disease Diseases 0.000 abstract 1
210000003169 central nervous system Anatomy 0.000 abstract 1
IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical compound C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 abstract 1
229960000258 corticotropin Drugs 0.000 abstract 1
230000006378 damage Effects 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
231100000234 hepatic damage Toxicity 0.000 abstract 1
229940125396 insulin Drugs 0.000 abstract 1
230000008818 liver damage Effects 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1
230000003278 mimic effect Effects 0.000 abstract 1
201000010065 polycystic ovary syndrome Diseases 0.000 abstract 1
230000035945 sensitivity Effects 0.000 abstract 1
ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 abstract 1
230000000451 tissue damage Effects 0.000 abstract 1
231100000827 tissue damage Toxicity 0.000 abstract 1
208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
Diabetes (AREA)
Molecular Biology (AREA)
Obesity (AREA)
Hematology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Mycology (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Biophysics (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pulmonology (AREA)
Oncology (AREA)
Emergency Medicine (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)

DK96907595T 1995-03-21 1996-03-20 Phosphoglycan-mimetika af hormoner og vækstfaktorer fra Mycobacterium vaccae DK0815255T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9505658.6A GB9505658D0 (en)	1995-03-21	1995-03-21	Hormone and growth factor mimetics
PCT/GB1996/000669 WO1996029425A1 (en)	1995-03-21	1996-03-20	Hormone and growth factor phosphoglycan mimetics from mycobacterium vaccae

Publications (1)

Publication Number	Publication Date
DK0815255T3 true DK0815255T3 (da)	2003-09-15

Family

ID=10771553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96907595T DK0815255T3 (da)	1995-03-21	1996-03-20	Phosphoglycan-mimetika af hormoner og vækstfaktorer fra Mycobacterium vaccae

Country Status (10)

Country	Link
US (1)	US6106822A (da)
EP (1)	EP0815255B1 (da)
JP (1)	JPH11503307A (da)
AT (1)	ATE240402T1 (da)
AU (1)	AU713221B2 (da)
DE (1)	DE69628155T2 (da)
DK (1)	DK0815255T3 (da)
ES (1)	ES2199285T3 (da)
GB (1)	GB9505658D0 (da)
WO (1)	WO1996029425A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9618929D0 (en)	1996-09-11	1996-10-23	Univ London	Metal containing carbohydrates from human tissue which regulate glycogen metabolism
GB9618930D0 (en) *	1996-09-11	1996-10-23	Univ London	Metal containing carbohydrates from human tissue which regulate lipogenic activity
GB9618934D0 (en) *	1996-09-11	1996-10-23	Univ London	Inositol phosphoglycans for therapeutic use in the treatment of diabetes and obesity
AU748080B2 (en) *	1998-03-18	2002-05-30	Rodaris Pharmaceuticals Limited	Anti-inositolphosphoglycan monoclonal antibodies
GB9805771D0 (en) *	1998-03-18	1998-05-13	Hoeft Rademacher Limited	Materials and methods relating to screening for inositolphosphoglycan mimetics
GB9806645D0 (en) *	1998-03-27	1998-05-27	Univ London	Materials and methods relating to the treatment of conditions involving mast cells,basophils and eosinophils
GB0010496D0 (en) *	2000-04-28	2000-06-14	Stanford Rook Ltd	Treatment of conditions of the central nervous system
US8357749B2 (en)	2003-08-25	2013-01-22	Dow Global Technologies Llc	Coating composition and articles made therefrom
US7803865B2 (en)	2003-08-25	2010-09-28	Dow Global Technologies Inc.	Aqueous dispersion, its production method, and its use
US8946329B2 (en)	2003-08-25	2015-02-03	Dow Global Technologies Llc	Coating compositions
US9169406B2 (en)	2003-08-25	2015-10-27	Dow Global Technologies Llc	Coating compositions
US8779053B2 (en)	2003-08-25	2014-07-15	Dow Global Technologies Llc	Coating compositions
US8349929B2 (en) *	2003-08-25	2013-01-08	Dow Global Technologies Llc	Coating composition and articles made therefrom
US8722787B2 (en)	2003-08-25	2014-05-13	Dow Global Technologies Llc	Coating composition and articles made therefrom
US7763676B2 (en)	2003-08-25	2010-07-27	Dow Global Technologies Inc.	Aqueous polymer dispersions and products from those dispersions
GB0716778D0 (en)	2007-08-29	2007-10-10	Bioeos Ltd	Use
KR102177644B1 (ko)	2012-12-28	2020-11-11	다우 글로벌 테크놀로지스 엘엘씨	코팅 조성물 및 그로부터 제조된 물품
CN104968736B (zh)	2012-12-28	2017-09-05	陶氏环球技术有限责任公司	涂料组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8919321D0 (en) *	1989-08-25	1989-10-11	Univ London	Treatment of chronic inflammatory conditions
GB9203814D0 (en) *	1992-02-21	1992-04-08	Univ London	Treatment of long term auto-immune conditions

1995
- 1995-03-21 GB GBGB9505658.6A patent/GB9505658D0/en active Pending
1996
- 1996-03-20 JP JP8528199A patent/JPH11503307A/ja not_active Ceased
- 1996-03-20 ES ES96907595T patent/ES2199285T3/es not_active Expired - Lifetime
- 1996-03-20 AT AT96907595T patent/ATE240402T1/de not_active IP Right Cessation
- 1996-03-20 DK DK96907595T patent/DK0815255T3/da active
- 1996-03-20 AU AU51164/96A patent/AU713221B2/en not_active Ceased
- 1996-03-20 US US08/913,604 patent/US6106822A/en not_active Expired - Fee Related
- 1996-03-20 WO PCT/GB1996/000669 patent/WO1996029425A1/en not_active Ceased
- 1996-03-20 EP EP96907595A patent/EP0815255B1/en not_active Expired - Lifetime
- 1996-03-20 DE DE69628155T patent/DE69628155T2/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU5116496A (en)	1996-10-08
ATE240402T1 (de)	2003-05-15
US6106822A (en)	2000-08-22
JPH11503307A (ja)	1999-03-26
DE69628155D1 (de)	2003-06-18
WO1996029425A1 (en)	1996-09-26
DE69628155T2 (de)	2003-12-18
GB9505658D0 (en)	1995-05-10
EP0815255B1 (en)	2003-05-14
ES2199285T3 (es)	2004-02-16
AU713221B2 (en)	1999-11-25
EP0815255A1 (en)	1998-01-07

Publication	Publication Date	Title
DE69628155D1 (de)	2003-06-18	Phosphoglycan-mimetika von hormonen und wachstumfaktoren aus mycobacterium vaccae
BR9106280A (pt)	1993-04-13	Composicoes adesivas de alfa-cianoacrilato
DK0536226T3 (da)	1997-02-10
SE9102798L (sv)	1993-03-27	Nytt konjugat, dess framstaellning och anvaendning samt substrat preparerat med konjugatet
NO940436D0 (no)	1994-02-09	Forlenget avgivelse av peptider
NO20090846L (no)	1999-12-17	Kombinasjon og farmasoytisk blanding for behandling av diabetes samt anvendelse derav
EP0671922A4 (en)	1996-08-21	LIQUIDIZED COLON SUBMUCOSA AND THEIR USE AS INJECTABLE TISSUE TRANSPLANT.
DE69737995D1 (de)	2007-09-20	INSULINPREPARATION MIT MAnnitol
SE9802080D0 (sv)	1998-06-11	Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein
BR9509019B1 (pt)	2009-01-13	comprimido isento de solventes orgÂnicos.
ATE249250T1 (de)	2003-09-15	Alginatfaser, verfahren zu ihrer herstellung und verwendung
NO2012003I1 (no)	2012-02-13	4-aminopyridin eller et derivat derav
NO994248L (no)	1999-10-20	Startsett med nikotinsyrepreparater
DK0607278T3 (da)	2002-06-17	Fremgangsmåde til forstærkning af tarmabsorption
ATE169225T1 (de)	1998-08-15	Anwendung von urodilatin bei lungen- und bronchialerkrankungen
DE68918944D1 (de)	1994-11-24	Künstliche rezeptor-analoge.
DE3882544D1 (de)	1993-09-02	Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
SG49785A1 (en)	1998-06-15	Use of 17 alpha dihydroequilenin for lowering cholesterol
FI932490A0 (fi)	1993-06-01	Underenhetsvaccin mot Neisseria meningitidis-infektioner och motsvarande underenheter i rent tillstaond
GR900100535A (en)	1991-12-10	Substituted 2-imidazolines and preparation and use thereof
KRUEGER et al.	1962	Studies on the effects of gaseous ions on the mammalian trachea
Inaba	1988	Long-term local vibration exposure: influence of frequencies on the occurrence of intimal thickening of peripheral arteries
Ui et al.	1986	Structure of islet-activating protein, pertussis toxin, required for its multiple biological activities.
SHIN et al.	1990	The etiology of diabetic impotence
Syed	1990	Tympanoplasty type I: review of 327 cases