DK0820448T3 - Nye taxoider, deres fremstilling og farmaceutiske præparater deraf - Google Patents

Nye taxoider, deres fremstilling og farmaceutiske præparater deraf

Info

Publication number
DK0820448T3
DK0820448T3 DK96913578T DK96913578T DK0820448T3 DK 0820448 T3 DK0820448 T3 DK 0820448T3 DK 96913578 T DK96913578 T DK 96913578T DK 96913578 T DK96913578 T DK 96913578T DK 0820448 T3 DK0820448 T3 DK 0820448T3
Authority
DK
Denmark
Prior art keywords
preparation
pharmaceutical compositions
new taxoids
taxoids
new
Prior art date
Application number
DK96913578T
Other languages
Danish (da)
English (en)
Inventor
Alain Commercon
Herve Bouchard
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0820448T3 publication Critical patent/DK0820448T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK96913578T 1995-04-14 1996-04-12 Nye taxoider, deres fremstilling og farmaceutiske præparater deraf DK0820448T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9504559A FR2732968B1 (fr) 1995-04-14 1995-04-14 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1996/000559 WO1996032387A1 (fr) 1995-04-14 1996-04-12 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
DK0820448T3 true DK0820448T3 (da) 2000-08-21

Family

ID=9478163

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96913578T DK0820448T3 (da) 1995-04-14 1996-04-12 Nye taxoider, deres fremstilling og farmaceutiske præparater deraf

Country Status (16)

Country Link
US (1) US5906990A (de)
EP (1) EP0820448B1 (de)
JP (1) JP4308905B2 (de)
AR (1) AR002041A1 (de)
AT (1) ATE193533T1 (de)
AU (1) AU5652296A (de)
DE (1) DE69608680T2 (de)
DK (1) DK0820448T3 (de)
ES (1) ES2148758T3 (de)
FR (1) FR2732968B1 (de)
GR (1) GR3033591T3 (de)
IL (1) IL117878A (de)
PT (1) PT820448E (de)
TW (1) TW349095B (de)
WO (1) WO1996032387A1 (de)
ZA (1) ZA962900B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7360396A (en) 1995-09-11 1997-04-01 Enzymed, Inc. Biocatalytic methods for synthesizing and identifying biologically active compounds
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
EP0982028A1 (de) * 1998-08-20 2000-03-01 Aventis Pharma S.A. Neue Verwendung von Taxoidverbindungen
MXPA01001721A (es) * 1998-08-20 2005-06-03 Aventis Pharma Sa Nuevo uso de derivados de taxoide.
EP1176957A1 (de) * 1999-05-03 2002-02-06 Aventis Pharma S.A. Verfahren zur behandlung von abnormaler zellproliferation des gehirns
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
PL350331A1 (en) 2000-02-02 2002-12-02 Univ Florida State Res Found C10 carbamoyloxy substituted taxanes as antitumor agents
SK13632001A3 (sk) 2000-02-02 2002-06-04 Florida State University Research Foundation, Inc. C10 karbonátom substituované taxány ako protinádorové činidlá
WO2002066448A1 (en) * 2001-02-20 2002-08-29 Dabur India Limited Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid
FR2853651B1 (fr) * 2003-04-14 2005-05-20 Aventis Pharma Sa Procede de preparation du 4,10 beta-diacetoxy-2 alpha- benzoyloxy-5 beta, 20-epoxy-1, 13 alpha-dihydroxy-9-oxo-19- norcyclopropa[g]tax-11-ene
US6956124B2 (en) 2003-04-14 2005-10-18 Aventis Pharma S.A. Process for the preparation of 4,10β-diacetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene
AU2003239511A1 (en) * 2003-05-20 2004-12-13 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
PE20050693A1 (es) * 2004-02-13 2005-09-27 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
WO2006088767A2 (en) * 2005-02-14 2006-08-24 Florida State University Research Foundation, Inc. C10 cyclopropyl ester substituted taxane compositions
US20090076127A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched larotaxel
EP2276755A4 (de) * 2008-03-31 2011-05-04 Univ Florida State Res Found C(10)-ethylester- und c(10)-cyclopropylester-substituierte taxane
EP2177630A1 (de) * 2008-10-02 2010-04-21 Institut Gustave Roussy Verfahren für die Prognose oder Überwachung, ob ein Patient mit Krebsleiden auf eine Behandlung mit einem Molekül aus der Taxoid-Familie anspricht

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710642B1 (fr) * 1993-09-29 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5395850A (en) * 1994-03-10 1995-03-07 Bristol-Myers Squibb Company 6,7-epoxy paclitaxels
FR2718135B1 (fr) * 1994-04-05 1996-04-26 Rhone Poulenc Rorer Sa Procédé de préparation d'hydroxy-7 taxanes.

Also Published As

Publication number Publication date
US5906990A (en) 1999-05-25
FR2732968B1 (fr) 1997-05-16
ZA962900B (en) 1996-07-30
DE69608680T2 (de) 2000-10-19
EP0820448B1 (de) 2000-05-31
GR3033591T3 (en) 2000-09-29
FR2732968A1 (fr) 1996-10-18
AR002041A1 (es) 1998-01-07
WO1996032387A1 (fr) 1996-10-17
AU5652296A (en) 1996-10-30
IL117878A (en) 2001-03-19
DE69608680D1 (de) 2000-07-06
EP0820448A1 (de) 1998-01-28
PT820448E (pt) 2000-09-29
JP4308905B2 (ja) 2009-08-05
IL117878A0 (en) 1996-08-04
JPH11503443A (ja) 1999-03-26
TW349095B (en) 1999-01-01
ATE193533T1 (de) 2000-06-15
ES2148758T3 (es) 2000-10-16

Similar Documents

Publication Publication Date Title
DK0817779T3 (da) Nye taxoider, deres fremstilling og farmaceutiske præparater deraf
DK0876362T3 (da) Nye taxoider, deres fremstilling og farmaceutiske præparater deraf
IS1947B (is) Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra
NO996433D0 (no) Nye formuleringer av legemidler, fremgangsmåter for fremstilling derav og fremgangsmåter for anvendelse derav
NO20001409L (no) Karboksamidotiazolderivater, fremgangsmÕte for fremstilling derav og farmasøytiske blandinger
DK1263721T3 (da) Farmaceutiske sammensætninger, der indeholder 3-aminoazetidinderivater, nye derivater og fremstilling deraf
FI973039A0 (fi) Uusia farnesyylitransferaasin inhibiittoreita, niiden valmistus ja niitä sisältäviä farmaseuttisia koostumuksia
FI973279A0 (fi) Uudet farnesyylitransferaasin inhibiittorit, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset
EE9500064A (et) Asendatud 1H-imidasoolid, nende valmistamismeetodid ja farmatseutilised kompositsioonid
NO975711D0 (no) Nye Dolastatinderivater, deres fremstilling og anvendelse
NO961160D0 (no) Cykliske forbindelser, deres fremstilling og anvendelse
IS4706A (is) Lyfjasamsetningar
NO952677D0 (no) Nye dihydropyrrolopyridinon- og oksazolopyridinonforbindelser, deres fremstilling og farmasöytiske preparater
EE03680B1 (et) Asendatud püridiinid, nende kasutamine ja farmatseutilised kompositsioonid
IS1846B (is) Setin N-(indól-2-karbónýl)-b-alaninamíð, notkun þeirra og lyfjaefnablöndur
DE69300913D1 (de) Polymorph Terazosin und pharmazeutische Zusammenstellung.
DK1112266T3 (da) Substituerede 4-amino-2-arylpyrimidiner, fremstilling og anvendelse deraf og farmaceutiske præparater indeholdende dem
NO20005266D0 (no) Nye substituerte amider, deres fremstilling og anvendelse
NO983472D0 (no) Taxoider, deres fremstilling og farmas°ytiske preparater inneholdende taxoidene
FI972988L (fi) Menetelmiä ja farmaseuttisia koostumuksia, joissa käytetään desmetyyliselegiliiniä
FI973229L (fi) Uusi farmaseuttinen koostumus
NO975365D0 (no) Benzopyraner og farmasöytiske sammensetninger inneholdende dem
NO980471L (no) Benzensulfonamidderivater, fremstilling derav og terapautiske anvendelser derav
NO981195D0 (no) Nye aminoresin sammensetninger
NO974057D0 (no) Bisykliske takykinin-antagonister, fremstilling derav og deres anvendelse i farmasöytisk sammensetning