DK0825867T3 - N,O-carboxymethylchitosan til forhindring af operationssammenvoksninger - Google Patents

N,O-carboxymethylchitosan til forhindring af operationssammenvoksninger

Info

Publication number
DK0825867T3
DK0825867T3 DK96915517T DK96915517T DK0825867T3 DK 0825867 T3 DK0825867 T3 DK 0825867T3 DK 96915517 T DK96915517 T DK 96915517T DK 96915517 T DK96915517 T DK 96915517T DK 0825867 T3 DK0825867 T3 DK 0825867T3
Authority
DK
Denmark
Prior art keywords
carboxymethylchitosan
coalescence
prevent surgical
surgical
prevent
Prior art date
Application number
DK96915517T
Other languages
English (en)
Inventor
Clive M Elson
Original Assignee
Chitogenics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chitogenics Inc filed Critical Chitogenics Inc
Application granted granted Critical
Publication of DK0825867T3 publication Critical patent/DK0825867T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0023—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/722—Chitin, chitosan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK96915517T 1995-05-08 1996-05-06 N,O-carboxymethylchitosan til forhindring af operationssammenvoksninger DK0825867T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/436,770 US5679658A (en) 1995-05-08 1995-05-08 N,O-carbonxymethylchitosan for prevention of surgical adhesions
PCT/US1996/006339 WO1996035433A1 (en) 1995-05-08 1996-05-06 N,o-carboxymethylchitosan for prevention of surgical adhesions

Publications (1)

Publication Number Publication Date
DK0825867T3 true DK0825867T3 (da) 2004-04-13

Family

ID=23733768

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96915517T DK0825867T3 (da) 1995-05-08 1996-05-06 N,O-carboxymethylchitosan til forhindring af operationssammenvoksninger

Country Status (8)

Country Link
US (1) US5679658A (da)
EP (1) EP0825867B1 (da)
JP (1) JPH11507018A (da)
CA (1) CA2220505C (da)
DE (1) DE69631044T2 (da)
DK (1) DK0825867T3 (da)
ES (1) ES2213175T3 (da)
WO (1) WO1996035433A1 (da)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888988A (en) * 1995-05-08 1999-03-30 Chitogenics, Inc. Covalently linked N,O-carboxymethylchitosan and uses thereof
CA2224253A1 (en) * 1995-06-09 1996-12-27 Martin J. Macphee Chitin hydrogels, methods of their production and use
US7083777B1 (en) 1999-04-02 2006-08-01 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
EP1459757A1 (en) 1999-04-02 2004-09-22 The Brigham And Women's Hospital, Inc. Immunomodulating polymers
US6645947B1 (en) * 1999-05-20 2003-11-11 Chitogenics, Inc. Adhesive N, O-carboxymethylchitosan coatings which inhibit attachment of substrate-dependent cells and proteins
SV2003000753A (es) 2000-12-05 2003-06-16 Brigham & Womens Hospital Uso de polisacaridos zwitterionicos para la especifica modulacion del progreso inmunologico
US20040033265A1 (en) * 2001-12-31 2004-02-19 Industrial Technology Research Institute Composite matrix containing chitosan derivatives and a process for making the same
US7265097B2 (en) * 2002-08-20 2007-09-04 Chitogenics, Inc. Methods of drug delivery using sulphated chitinous polymers
WO2004089407A2 (en) 2003-03-31 2004-10-21 The Brigham And Women's Hospital, Inc. Zwitterionic immunomodulators for the treatment of asthma and allergy
US7332179B2 (en) * 2003-12-12 2008-02-19 Kimberly-Clark Worldwide, Inc. Tissue products comprising a cleansing composition
US20050244480A1 (en) * 2004-04-30 2005-11-03 Kimberly-Clark Worldwide, Inc. Pre-wipes for improving anal cleansing
US20060140899A1 (en) * 2004-12-28 2006-06-29 Kimberly-Clark Worldwide, Inc. Skin cleansing system comprising an anti-adherent formulation and a cationic compound
US7642395B2 (en) * 2004-12-28 2010-01-05 Kimberly-Clark Worldwide, Inc. Composition and wipe for reducing viscosity of viscoelastic bodily fluids
US8414907B2 (en) 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US8206726B2 (en) 2006-02-06 2012-06-26 The Brigham And Women's Hospital, Inc. Zwitterionic polysaccharides for promotion of immune system maturation and health
US20070181631A1 (en) * 2006-02-07 2007-08-09 Ethicon Endo-Surgery, Inc. Apparatus for performing trans-anal resection
KR101610268B1 (ko) 2007-08-28 2016-04-07 애들레이드 리서치 앤드 이노베이션 피티와이 리미티드 외과용 하이드로겔
JP2011503104A (ja) 2007-11-09 2011-01-27 カリフォルニア インスティテュート オブ テクノロジー 免疫調節化合物ならびに関連組成物および方法
EP2095832A1 (de) 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.
BRPI0801422B8 (pt) * 2008-03-26 2021-05-25 Fund Sao Francisco Xavier composição e método para inibição da severidade das aderências pós-cirúrgicas
CN102883715B (zh) 2008-04-24 2014-11-12 麦德托尼克公司 包含壳聚糖的保护性组合物
CN102065849B (zh) * 2008-04-24 2015-04-29 麦德托尼克公司 基于壳聚糖和氧化多糖的保护性凝胶
JP2011518837A (ja) 2008-04-24 2011-06-30 メドトロニック，インコーポレイテッド 再水和可能なチオール化多糖粒子およびスポンジ
WO2009132229A2 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Cold ionizing radiation sterilization
US8556139B2 (en) * 2008-12-04 2013-10-15 Abdulmohsen A Almoumen Multi-functional bag with cushion
JP6027961B2 (ja) 2010-04-07 2016-11-16 シェン, ユエSHEN, Yue 粘膜へ化合物を送るための媒体、それに関連する組成物、方法、及びシステム
JP2013530949A (ja) 2010-05-20 2013-08-01 エル ラウンド ジューン 抗原特異的Ｔｒｅｇ並びに関連する組成物、方法及びシステム
US9539281B2 (en) 2011-07-12 2017-01-10 The Brigham And Women's Hospital, Inc. Lipid-containing PSA compositions, methods of isolation and methods of use thereof
EP2612846A1 (de) 2012-01-09 2013-07-10 Bayer MaterialScience AG Beta-Aminosäureester und deren Verwendung
CA2911826C (en) 2013-05-10 2022-08-23 California Institute Of Technology Probiotic prevention and treatment of colon cancer
CN104337834B (zh) * 2014-11-10 2017-06-30 河北爱能生物科技股份有限公司 一种羧甲基壳聚糖灌肠液
WO2016201342A1 (en) 2015-06-10 2016-12-15 California Institute Of Technology Sepsis treatment and related compositions methods and systems
JP6918365B2 (ja) 2015-08-19 2021-08-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 脂質化ｐｓａ組成物および方法
US11491181B2 (en) 2016-07-15 2022-11-08 President And Fellows Of Harvard College Glycolipid compositions and methods of use
FR3074043B1 (fr) 2017-11-28 2020-11-13 Kiomed Pharma Chitosane a charge anionique
FR3074044B1 (fr) * 2017-11-28 2019-11-01 Kiomed Pharma Carboxyalkyl chitosane
CN108744026A (zh) * 2018-06-09 2018-11-06 江苏海尔滋生物科技有限公司 即配型几丁多糖冻干粉
FR3096260B1 (fr) * 2019-05-24 2022-05-27 Kiomed Pharma Chitosane et ses applications

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141973A (en) * 1975-10-17 1979-02-27 Biotrics, Inc. Ultrapure hyaluronic acid and the use thereof
SE456346B (sv) * 1984-07-23 1988-09-26 Pharmacia Ab Gel for att forhindra adhesion mellan kroppsvevnader och sett for dess framstellning
US4619995A (en) * 1984-12-24 1986-10-28 Nova Chem Limited N,O-carboxymethyl chitosan and preparative method therefor
US4819617A (en) * 1986-09-04 1989-04-11 University Of Florida Viscoelastic material for ophthalmic surgery
US5080893A (en) * 1988-05-31 1992-01-14 University Of Florida Method for preventing surgical adhesions using a dilute solution of polymer
US5023090A (en) * 1989-08-16 1991-06-11 Levin Robert H Topical compositions containing LYCD and other topically active medicinal ingredients for the treatment of ACNE
US5140016A (en) * 1988-05-31 1992-08-18 University Of Florida Method and composition for preventing surgical adhesions using a dilute solution of polymer
US5093319A (en) * 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
US5462990A (en) * 1990-10-15 1995-10-31 Board Of Regents, The University Of Texas System Multifunctional organic polymers
JPH0826081B2 (ja) * 1991-12-20 1996-03-13 ハウメディカ・インコーポレーテッド キトサンのｎ−カルボキシアルキル誘導体を不溶化する方法
US5411988A (en) * 1993-10-27 1995-05-02 Bockow; Barry I. Compositions and methods for inhibiting inflammation and adhesion formation
EP0665022A1 (en) * 1994-01-28 1995-08-02 Prodex, Inc. Viscoelastic solution of N,O-carboxymethyl chitosan for ophthalmic use

Also Published As

Publication number Publication date
EP0825867B1 (en) 2003-12-10
WO1996035433A1 (en) 1996-11-14
CA2220505C (en) 2008-02-19
EP0825867A4 (en) 2000-05-31
CA2220505A1 (en) 1996-11-14
JPH11507018A (ja) 1999-06-22
DE69631044D1 (de) 2004-01-22
DE69631044T2 (de) 2004-07-22
US5679658A (en) 1997-10-21
ES2213175T3 (es) 2004-08-16
EP0825867A1 (en) 1998-03-04

Similar Documents

Publication Publication Date Title
DK0825867T3 (da) N,O-carboxymethylchitosan til forhindring af operationssammenvoksninger
DE69839989D1 (de) Bildgesteuertes chirurgisches system
DE69636353D1 (de) Datenübetragungsvorrichtung.
MX206776B (es) Compuestos no tejidos hidroenredados.
FI950715A0 (fi) Ytmikromekanisk, symmetrisk tryckskillnadsgivare
DK0937055T3 (da) Fremgangsmåde til fremstilling af d,I-alfa-tocopherol
NL1003765A1 (nl) Opvoedkundige inrichting.
DZ1986A1 (fr) Utilisation de phénylcyclohexylcarboxamides.
DK0948888T3 (da) System til behandling af gødning
NO982304D0 (no) 25-Hydroksy-16-ene-26,27-bishomo-cholecalciferoler
DK0815092T3 (da) Fremgangsmåde til fremstilling af 1,2-benzisothiazolin-3-oner
DK0810216T3 (da) Derivater af 10,11-dihydro-10-oxo-5H-dibenz/b/,f/azepin-5-carboxamid
NL1000591C2 (nl) Weefsel.
FR2709944B1 (fr) Agrafe chirurgicale.
ES1032571Y (es) Gafa,
NL1000001A1 (nl) Stal.
DK0783491T3 (da) Fremgangsmåde til fremstilling af 3,3,5-trichlorglutarimid
NL1001013A1 (nl) Technoclip.
EP0873349A4 (en) Endothelial-monocyte activating polypeptide iii
ES1034314Y (es) Conjunto de formularios de multiples aplicaciones.
FI952912A0 (fi) Traedcylinder, gripelement med traedrotsprincip
FI950956A0 (fi) Luftkabel, saosom haengspiralkabel
FI952416A0 (fi) Distributionsanordning foer vaetska, speciellt tvaettvaetska foer vindrutor
ES1031505Y (es) Estuche de cerillas perfeccionado.
ES1029967Y (es) Juego-juguete de habilidad.