DK0832900T3 - Peptid og fremgangsmåde til opnåelse af det - Google Patents

Peptid og fremgangsmåde til opnåelse af det

Info

Publication number
DK0832900T3
DK0832900T3 DK96915261T DK96915261T DK0832900T3 DK 0832900 T3 DK0832900 T3 DK 0832900T3 DK 96915261 T DK96915261 T DK 96915261T DK 96915261 T DK96915261 T DK 96915261T DK 0832900 T3 DK0832900 T3 DK 0832900T3
Authority
DK
Denmark
Prior art keywords
trp
nval
ile
tyr
phe
Prior art date
Application number
DK96915261T
Other languages
English (en)
Inventor
Vladislav Isakovich Deigin
Andrei Marxovich Korotkov
Original Assignee
Immunotech Dev Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20168146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0832900(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunotech Dev Inc filed Critical Immunotech Dev Inc
Application granted granted Critical
Publication of DK0832900T3 publication Critical patent/DK0832900T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • C07K5/0823Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp and Pro-amino acid; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1016Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK96915261T 1995-06-07 1996-05-06 Peptid og fremgangsmåde til opnåelse af det DK0832900T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU95108559A RU2107692C1 (ru) 1995-06-07 1995-06-07 Пептид и способ его получения
PCT/RU1996/000116 WO1996040740A1 (fr) 1995-06-07 1996-05-06 Peptide et procede de production
US08/657,888 US5736519A (en) 1995-06-07 1996-06-07 Peptide, a method for its preparation and a pharmaceutical composition containing the peptide

Publications (1)

Publication Number Publication Date
DK0832900T3 true DK0832900T3 (da) 2004-06-21

Family

ID=20168146

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96915261T DK0832900T3 (da) 1995-06-07 1996-05-06 Peptid og fremgangsmåde til opnåelse af det

Country Status (20)

Country Link
US (1) US5736519A (da)
EP (1) EP0832900B1 (da)
JP (1) JP4082522B2 (da)
CN (1) CN1154653C (da)
AT (1) ATE260933T1 (da)
AU (1) AU724781B2 (da)
BR (1) BRPI9609235B8 (da)
CA (1) CA2222296C (da)
CZ (1) CZ287816B6 (da)
DE (1) DE69631762T2 (da)
DK (1) DK0832900T3 (da)
ES (1) ES2217311T3 (da)
HU (1) HU228461B1 (da)
LT (1) LT4476B (da)
LV (1) LV12074B (da)
PT (1) PT832900E (da)
RU (1) RU2107692C1 (da)
SK (1) SK281825B6 (da)
UA (1) UA48974C2 (da)
WO (1) WO1996040740A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2107691C1 (ru) * 1995-03-02 1998-03-27 Дейгин Владислав Исакович Пептид и способ его получения
US5916878A (en) * 1995-11-28 1999-06-29 Edward T. Wei γ-glutamyl and β-aspartyl containing immunomodulator compounds and methods therewith
US6159940A (en) * 1996-02-28 2000-12-12 Immunotech Developments Inc. Method for modulating hemopoiesis
DE19712633A1 (de) * 1997-03-26 1998-10-08 Laves Arzneimittel Verwendung von gamma-Aminobuttersäure als Interleukinbildungsstimulans
IL145926A0 (en) 2001-10-15 2002-07-25 Mor Research Applic Ltd Peptide epitopes of mimotopes useful in immunomodulation
IL155136A0 (en) 2003-02-10 2003-10-31 Enzymotec Ltd A composition for reducing blood cholesterol and triglycerides
US20060233863A1 (en) 2003-02-10 2006-10-19 Enzymotec Ltd. Oils enriched with diacylglycerols and phytosterol esters and unit dosage forms thereof for use in therapy
BRPI0408892A (pt) * 2003-03-28 2006-04-11 Sciclone Pharmaceuticals Inc uso de timosina alfa 1 para tratar as infecções por arpergillus
EP1776159A1 (en) * 2004-08-09 2007-04-25 Enzymotec Ltd. Food products for diabetics
AU2005270831B2 (en) 2004-08-10 2011-08-25 Enzymotec Ltd. Mixture of phytosterol ester(s) and 1, 3-diglyceride(s) for use in the treatment of medical conditions
US7691807B2 (en) * 2005-03-18 2010-04-06 Centre National De La Recherche Scientifique (Cnrs) Hybrid oligomers, their preparation process and pharmaceutical compositions containing them
EP1865950B1 (en) * 2005-04-07 2013-08-28 Centre National de la Recherche Scientifique Compounds useful as modulators of the proteasome activity
US20100129288A1 (en) * 2005-06-28 2010-05-27 Elior Peles Gliomedin, Fragments Thereof and Methods of Using Same
RU2320364C1 (ru) * 2006-08-21 2008-03-27 Закрытое Акционерное Общество "Центр "Пептос" Способ лечения злокачественных новообразований
CA2569204A1 (en) 2006-11-28 2008-05-28 Apotex Technologies Inc. Crystalline d-isoglutamyl-d-tryptophan and the mono ammonium salt of d-isoglutamyl-d-tryptophan
CA2571645A1 (en) 2006-12-19 2008-06-19 Apotex Technologies Inc. Pharmaceutically acceptable salts of thymodepressin and processes for their manufacture
CA2677749A1 (en) 2007-02-13 2008-08-21 Sciclone Pharmaceuticals, Inc. Method of treating or preventing tissue deterioration, injury or damage due to disease of mucosa
CA2579119C (en) 2007-02-16 2013-03-05 Apotex Technologies Inc. Crystalline forms of the mono-sodium salt of d-isoglutamyl-d-tryptophan
US20100150924A1 (en) * 2007-05-22 2010-06-17 Elior Peles Regulation of myelination by nectin-like (necl) molecules
RU2410391C1 (ru) * 2009-06-03 2011-01-27 Общество с ограниченной ответственностью "Пептос Фарма" Пептиды, влияющие на регенерацию кроветворной системы, и фармацевтическая композиция на их основе
CN103502214A (zh) * 2011-03-31 2014-01-08 阿普泰克斯科技公司 D-异谷氨酰基-[d/l]-色氨酸的前药
AU2012234689A1 (en) * 2011-03-31 2013-10-17 Apotex Technologies Inc. Prodrugs of D-gamma-glutamyl-D-tryptophan and D-gamma- glutamyl-L-tryptophan
CN102417474B (zh) * 2011-09-26 2014-07-02 深圳翰宇药业股份有限公司 D-异谷氨酰基-d-色氨酸制备的新方法
RU2634258C1 (ru) * 2016-11-08 2017-10-24 федеральное государственное автономное образовательное учреждение высшего образования "Российский университет дружбы народов" (РУДН) Наполнитель для капсульного ингалятора

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3832337A (en) * 1970-07-28 1974-08-27 Squibb & Sons Inc Peptide enzyme inhibitors
GB1526367A (en) * 1976-10-12 1978-09-27 Ici Ltd Polypeptide
HU184481B (en) * 1981-10-02 1984-08-28 Richter Gedeon Vegyeszet Process for producing tripeptides for diminishing appetite
JPS5921656A (ja) * 1982-07-28 1984-02-03 Takeda Chem Ind Ltd ポリペプチド誘導体
CH659586A5 (de) * 1985-07-02 1987-02-13 Le G Ped I Arzneimittel aus dem thymus und verfahren zu dessen herstellung.
CA1286989C (en) * 1985-12-26 1991-07-30 A. Arthur Gottlieb Immunoamplifiers and related compositions
IT1216908B (it) * 1987-03-19 1990-03-14 Eniricerche Spa Analoghi retro-inversi della timopentina e dei suoi frammenti, il metodo per la loro sintesi ed il loro impiego per la preparazionedi composizioni farmaceutiche.
WO1989006134A1 (fr) * 1987-12-30 1989-07-13 Vsesojuzny Kardiologichesky Nauchny Tsentr Akademi Preparation pharmaceutique pour traiter des etats immunodeficitaires
US5021551A (en) * 1989-01-18 1991-06-04 Washington University Method of enhancing peptide immunogenicity
SU1737798A1 (ru) * 1989-04-11 1995-03-20 Институт клинической иммунологии СО АМН СССР Способ получения иммуностимулирующих тимусных полипептидов
IT1230733B (it) 1989-06-30 1991-10-29 Eniricerche Spa Analoghi della timopentina retro invertita a tutti i legami, il metodo per la loro sintesi ed il loro impiego per la preparazione di composizioni farmaceutiche.
IT1263042B (it) * 1993-01-15 1996-07-24 Enichem Polimeri Composizione da stampaggio a base di polifenilenetere
WO1995003067A1 (en) * 1993-07-21 1995-02-02 Khavinson Vladimir Khatskelevi Pharmaceutical with immunomodulating activity

Also Published As

Publication number Publication date
ES2217311T3 (es) 2004-11-01
AU5707696A (en) 1996-12-30
HUP9801990A2 (hu) 1999-02-01
EP0832900A4 (en) 1999-10-06
CA2222296A1 (en) 1996-12-19
CA2222296C (en) 2001-10-09
SK281825B6 (sk) 2001-08-06
HU228461B1 (en) 2013-03-28
CZ287816B6 (en) 2001-02-14
LV12074A (lv) 1998-06-20
ATE260933T1 (de) 2004-03-15
HUP9801990A3 (en) 1999-06-28
BR9609235A (pt) 1999-12-21
JP4082522B2 (ja) 2008-04-30
EP0832900B1 (en) 2004-03-03
CZ390597A3 (cs) 1998-08-12
LT4476B (lt) 1999-03-25
PT832900E (pt) 2004-07-30
DE69631762D1 (de) 2004-04-08
JPH11513016A (ja) 1999-11-09
UA48974C2 (uk) 2002-09-16
DE69631762T2 (de) 2005-03-10
BRPI9609235B8 (pt) 2016-09-27
US5736519A (en) 1998-04-07
CN1189837A (zh) 1998-08-05
AU724781B2 (en) 2000-09-28
BR9609235B1 (pt) 2009-01-13
LT98004A (en) 1998-10-26
WO1996040740A1 (fr) 1996-12-19
RU2107692C1 (ru) 1998-03-27
SK166997A3 (en) 1998-04-08
CN1154653C (zh) 2004-06-23
EP0832900A1 (en) 1998-04-01
LV12074B (lv) 1998-08-20
HK1014965A1 (en) 1999-10-08

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