DK0840735T3 - Spaltning af 1-azabicyclo[2.2.2]octan-3-amin, 2-(diphenylmethyl)-N-2-methoxy-5-(1methylethyl)phenyl]methyl] - Google Patents

Spaltning af 1-azabicyclo[2.2.2]octan-3-amin, 2-(diphenylmethyl)-N-2-methoxy-5-(1methylethyl)phenyl]methyl]

Info

Publication number: DK0840735T3
Authority: DK; Denmark
Prior art keywords: diphenylmethyl; azabicyclo; octane; cleavage; methoxy
Prior art date: 1995-07-17

Application number

DK96918801T

Other languages

Danish (da)

English (en)

Inventor

Derek L Tickner

Morgan Meltz

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-07-17

Filing date

1996-07-04

Publication date

2004-02-09

1996-07-04 Application filed by Pfizer filed Critical Pfizer

2004-02-09 Application granted granted Critical

2004-02-09 Publication of DK0840735T3 publication Critical patent/DK0840735T3/da

Links

238000003776 cleavage reaction Methods 0.000 title 1
125000005982 diphenylmethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])(*)C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 title 1
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 title 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
230000007017 scission Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)

DK96918801T 1995-07-17 1996-07-04 Spaltning af 1-azabicyclo[2.2.2]octan-3-amin, 2-(diphenylmethyl)-N-2-methoxy-5-(1methylethyl)phenyl]methyl] DK0840735T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US119195P	1995-07-17	1995-07-17
PCT/IB1996/000648 WO1997003984A1 (en)	1995-07-17	1996-07-04	Resolution of 1-azabicyclo[2.2.2]octan-3-amine, 2-(diphenylmethyl)-n-[[2-methoxy-5-(1-methylethyl)phenyl]methyl]

Publications (1)

Publication Number	Publication Date
DK0840735T3 true DK0840735T3 (da)	2004-02-09

Family

ID=21694832

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96918801T DK0840735T3 (da)	1995-07-17	1996-07-04	Spaltning af 1-azabicyclo[2.2.2]octan-3-amin, 2-(diphenylmethyl)-N-2-methoxy-5-(1methylethyl)phenyl]methyl]

Country Status (25)

Country	Link
US (1)	US6008357A (cs)
EP (1)	EP0840735B1 (cs)
JP (1)	JP3043074B2 (cs)
KR (1)	KR100276989B1 (cs)
CN (1)	CN1068598C (cs)
AR (1)	AR002772A1 (cs)
AT (1)	ATE250600T1 (cs)
AU (1)	AU697553B2 (cs)
CA (1)	CA2227194C (cs)
CO (1)	CO4480720A1 (cs)
CZ (1)	CZ15098A3 (cs)
DE (1)	DE69630123T2 (cs)
DK (1)	DK0840735T3 (cs)
ES (1)	ES2205039T3 (cs)
HU (1)	HUP9900238A3 (cs)
IL (1)	IL122655A0 (cs)
MY (1)	MY115734A (cs)
NO (1)	NO980211L (cs)
NZ (1)	NZ310539A (cs)
PE (1)	PE8798A1 (cs)
PL (1)	PL184261B1 (cs)
PT (1)	PT840735E (cs)
RU (1)	RU2136681C1 (cs)
WO (1)	WO1997003984A1 (cs)
ZA (1)	ZA966026B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2405594T3 (es) *	2002-09-25	2013-05-31	Memory Pharmaceuticals Corporation	Idazoles, benzotiazoles y benzisotiazoles, y preparación y usos de los mismos
US6861526B2 (en) *	2002-10-16	2005-03-01	Pfizer Inc.	Process for the preparation of (S,S)-cis-2-benzhydryl-3-benzylaminoquinuclidine
BRPI0507334A (pt) *	2004-02-02	2007-07-03	Pfizer Prod Inc	processo para a preparação de -1(2s,3s)-2-benzidril-n-(5-terc-butil-2-metoxibenzila)q uinuclidin-3-amina
JP2008519837A (ja) *	2004-11-10	2008-06-12	ベーリンガーインゲルハイムケミカルズインコーポレイテッド	フェンタニル中間体の生成方法
SG172057A1 (en) *	2008-12-09	2011-07-28	Univ Florida	Kinase inhibitor compounds
US20160332962A1 (en)	2015-05-13	2016-11-17	Janssen Pharmaceutica Nv	(s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN108341812A (zh) *	2017-01-23	2018-07-31	科贝源(北京)生物医药科技有限公司	一种含奎宁环化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1990005525A1 (en) *	1988-11-23	1990-05-31	Pfizer Inc.	Quinuclidine derivatives as substance p antagonists
NO168529C (no) *	1989-09-15	1992-03-04	Chiron Lab As	Fremgangsmaate for fremstilling av s-(-) og r-(+)-n-(quinuclidinyl-3)-amider.
UA26401C2 (uk) *	1991-05-22	1999-08-30	Пфайзер Інк.	Заміщеhі 3-аміhохіhуклідиhи
WO1992021677A1 (en) *	1991-05-31	1992-12-10	Pfizer Inc.	bibNUCLIDINE DERIVATIVES
US5604241A (en) *	1992-10-21	1997-02-18	Pfizer Inc.	Substituted benzylaminoquinuclidines as substance P antagonists

1996
- 1996-07-03 PE PE1996000507A patent/PE8798A1/es not_active Application Discontinuation
- 1996-07-04 DE DE69630123T patent/DE69630123T2/de not_active Expired - Fee Related
- 1996-07-04 CZ CZ98150A patent/CZ15098A3/cs unknown
- 1996-07-04 ES ES96918801T patent/ES2205039T3/es not_active Expired - Lifetime
- 1996-07-04 IL IL12265596A patent/IL122655A0/xx unknown
- 1996-07-04 HU HU9900238A patent/HUP9900238A3/hu unknown
- 1996-07-04 PT PT96918801T patent/PT840735E/pt unknown
- 1996-07-04 EP EP96918801A patent/EP0840735B1/en not_active Expired - Lifetime
- 1996-07-04 US US08/981,750 patent/US6008357A/en not_active Expired - Fee Related
- 1996-07-04 JP JP9506471A patent/JP3043074B2/ja not_active Expired - Fee Related
- 1996-07-04 AT AT96918801T patent/ATE250600T1/de not_active IP Right Cessation
- 1996-07-04 NZ NZ310539A patent/NZ310539A/en unknown
- 1996-07-04 RU RU98101101A patent/RU2136681C1/ru not_active IP Right Cessation
- 1996-07-04 CA CA002227194A patent/CA2227194C/en not_active Expired - Fee Related
- 1996-07-04 CN CN96195567A patent/CN1068598C/zh not_active Expired - Fee Related
- 1996-07-04 AU AU61348/96A patent/AU697553B2/en not_active Ceased
- 1996-07-04 WO PCT/IB1996/000648 patent/WO1997003984A1/en not_active Ceased
- 1996-07-04 PL PL96324610A patent/PL184261B1/pl not_active IP Right Cessation
- 1996-07-04 KR KR1019980700362A patent/KR100276989B1/ko not_active Expired - Fee Related
- 1996-07-04 DK DK96918801T patent/DK0840735T3/da active
- 1996-07-05 AR ARP960103482A patent/AR002772A1/es not_active Application Discontinuation
- 1996-07-15 CO CO96037152A patent/CO4480720A1/es unknown
- 1996-07-16 ZA ZA9606026A patent/ZA966026B/xx unknown
- 1996-07-17 MY MYPI96002939A patent/MY115734A/en unknown
1998
- 1998-01-16 NO NO980211A patent/NO980211L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NZ310539A (en)	1998-11-25
MX9800538A (es)	1998-05-31
PL184261B1 (pl)	2002-09-30
EP0840735A1 (en)	1998-05-13
KR19990029058A (ko)	1999-04-15
JP3043074B2 (ja)	2000-05-22
WO1997003984A1 (en)	1997-02-06
ZA966026B (en)	1998-01-16
US6008357A (en)	1999-12-28
DE69630123T2 (de)	2004-04-08
AU6134896A (en)	1997-02-18
JPH10511102A (ja)	1998-10-27
PE8798A1 (es)	1998-03-02
HUP9900238A2 (hu)	1999-05-28
MY115734A (en)	2003-08-30
PT840735E (pt)	2004-02-27
CO4480720A1 (es)	1997-07-09
CN1190970A (zh)	1998-08-19
EP0840735B1 (en)	2003-09-24
CZ15098A3 (cs)	1999-02-17
AR002772A1 (es)	1998-04-29
RU2136681C1 (ru)	1999-09-10
NO980211L (no)	1998-03-16
AU697553B2 (en)	1998-10-08
CA2227194C (en)	2002-02-12
CA2227194A1 (en)	1997-02-06
HK1010195A1 (en)	1999-06-17
IL122655A0 (en)	1998-08-16
CN1068598C (zh)	2001-07-18
PL324610A1 (en)	1998-06-08
HUP9900238A3 (en)	2001-08-28
NO980211D0 (no)	1998-01-16
KR100276989B1 (ko)	2001-01-15
ES2205039T3 (es)	2004-05-01
DE69630123D1 (en)	2003-10-30
ATE250600T1 (de)	2003-10-15

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BR9611436A (pt)	1999-03-23	D-tartarato de (-)-cis-6(s)-fenil-5(r)-[4-(2-pirrolidin-1-iletóxi) fenil]-5,6,7,8,-tetra-hidronaftalen-2-ol
ID24455A (id)	2000-07-20	Alat untuk penyatuan-amorf pipa-pipa
CY2007024I1 (el)	2010-07-28	Kαινοφανη παραγωγα 3.3-διαφαινυλοπροπυλινων
BR9607097A (pt)	1997-11-11	Novos compostos
PT907650E (pt)	2003-04-30	N-¬4-(heteroarilmetil)fenil\|heteroarilaminasc
BR9600534A (pt)	1997-05-13	Novos compostos
ID20053A (id)	1998-09-17	Hipolipidemat 1,4-benzotiazepin-1,1-dioksida
PT1000048E (pt)	2003-03-31	Derivados substituidos do 1,2,3,4-tetrahidronaftaleno
CY2004003I2 (el)	2009-11-04	Παραγωγα 2-(2-αμινο-1, 6-διϋδρο-6-οξο-πυρινο-9-υλο)-μεθοδυ-1,3-προπανεδιολης
DK0820451T3 (da)	2003-05-12	Hidtil ukendte heterocykliske forbindelser
DK0754407T3 (da)	2002-04-22	Flydende formuleringer af 1,2-benzisothiazolin-3-on
TR199600137A2 (tr)	1996-10-21	Bitümlü bilesimler.
TR199800988A3 (tr)	1998-12-21	5' Deoksi-Sitidin türevleri.
FI971674A0 (fi)	1997-04-18	Heterosyklisen ryhmän sisältämät di-tert-butyyli-fenoliyhdisteet, käyttökelpoisia tulehduksenvastaisina aineina
DK0927173T3 (da)	2002-09-16	Substituerede [2-(1-piperazinyl)ethoxy]methylforbindelser
MA23779A1 (fr)	1996-10-01	Compose 9-substitue 2-(2-n-alkoxyphenyl) - purine -6- ones
IT1302243B1 (it)	2000-09-05	Sintesi dell'1,1,1,3,3-pentafluoropropano.
DK0840735T3 (da)	2004-02-09	Spaltning af 1-azabicyclo[2.2.2]octan-3-amin, 2-(diphenylmethyl)-N-2-methoxy-5-(1methylethyl)phenyl]methyl]
DK0815092T3 (da)	1999-12-06	Fremgangsmåde til fremstilling af 1,2-benzisothiazolin-3-oner
DK0735043T3 (da)	1998-10-07	Fremgangsmåde til fremstilling af 2-substitueret 3,3-difluorfuran
DK0810216T3 (da)	2001-07-23	Derivater af 10,11-dihydro-10-oxo-5H-dibenz/b/,f/azepin-5-carboxamid
ID16434A (id)	1997-09-25	Senyawa-senyawa 1,4-dihidropiridin
ES1031116Y (es)	1996-05-01	Barredora perfeccionada.
FR2724962B3 (fr)	1996-08-23	Tuile d'avant-toit sous-faitiere.
DK0783491T3 (da)	2002-01-21	Fremgangsmåde til fremstilling af 3,3,5-trichlorglutarimid