DK0854873T3 - Galathanminderivater og fremgangsmåde til deres fremstilling - Google Patents
Galathanminderivater og fremgangsmåde til deres fremstillingInfo
- Publication number
- DK0854873T3 DK0854873T3 DK96931169T DK96931169T DK0854873T3 DK 0854873 T3 DK0854873 T3 DK 0854873T3 DK 96931169 T DK96931169 T DK 96931169T DK 96931169 T DK96931169 T DK 96931169T DK 0854873 T3 DK0854873 T3 DK 0854873T3
- Authority
- DK
- Denmark
- Prior art keywords
- pct
- hydrogen
- galatine
- miner
- derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000007243 oxidative cyclization reaction Methods 0.000 abstract 1
- 150000003512 tertiary amines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9519267.0A GB9519267D0 (en) | 1995-09-21 | 1995-09-21 | Preparation of alkaloids |
| PCT/GB1996/002334 WO1997011077A1 (en) | 1995-09-21 | 1996-09-23 | Galanthamine derivatives and process for their preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0854873T3 true DK0854873T3 (da) | 2002-07-01 |
Family
ID=10781038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96931169T DK0854873T3 (da) | 1995-09-21 | 1996-09-23 | Galathanminderivater og fremgangsmåde til deres fremstilling |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US6093815A (de) |
| EP (1) | EP0854873B1 (de) |
| AT (1) | ATE214070T1 (de) |
| AU (1) | AU714711B2 (de) |
| CA (1) | CA2230826C (de) |
| CY (1) | CY2301B1 (de) |
| DE (1) | DE69619685T2 (de) |
| DK (1) | DK0854873T3 (de) |
| ES (1) | ES2173316T3 (de) |
| GB (1) | GB9519267D0 (de) |
| PT (1) | PT854873E (de) |
| WO (1) | WO1997011077A1 (de) |
| ZA (1) | ZA968028B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1604653A1 (de) | 1998-09-30 | 2005-12-14 | Takeda Pharmaceutical Company Limited | Acetylcholinesterase-Inhibitoren zur Verbesserung der Ausscheidungskraft der Harnblase |
| JP2003136077A (ja) * | 2001-10-31 | 2003-05-13 | Nec Corp | 半導体製造に用いる洗浄水又は浸漬水の製造装置 |
| WO2005065662A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Solid dosage formulations of galantamine |
| WO2005065661A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Immediate, controlled and sustained release formulations of galanthamine |
| WO2006124584A2 (en) * | 2005-05-13 | 2006-11-23 | Alza Corporation | Multilayer drug delivery system with barrier against reservoir material flow |
| WO2007035941A2 (en) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Transdermal galantamine delivery system |
| AT504663B1 (de) | 2007-02-22 | 2008-07-15 | Sanochemia Pharmazeutika Ag | Verfahren zum herstellen von hochreinen 4a,5,9,10,11,12,-hexahydro-6h-benzofuro(3a,3,2- f)(2) benzazepinen sowie dessen derivaten |
| EP2009015B1 (de) * | 2007-06-18 | 2012-01-11 | Aurobindo Pharma Limited | Herstellungsprozess für Galantaminhydrobromid |
| AT507039A1 (de) | 2008-06-26 | 2010-01-15 | Sanochemia Pharmazeutika Ag | Verfahren zum herstellen von hochreinen benzazepinderivaten |
| CN106977412B (zh) * | 2017-05-15 | 2019-08-02 | 张家港威胜生物医药有限公司 | 一种加兰他敏关键中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2755403B2 (ja) * | 1987-05-04 | 1998-05-20 | デイービス、ボニー | アルツハイマー病の治療のための化合物 |
| AT401058B (de) * | 1994-10-21 | 1996-06-25 | Waldheim Pharmazeutika Gmbh | Verfahren zum herstellen von derivaten des 4a,5, 9,10,11,12,-hexahydro-6h-benzofuro(3a,-3,2-ef) (2)benzazepins |
| NZ294191A (en) * | 1994-10-21 | 1998-10-28 | Waldheim Pharmazeutika Gmbh | Process for preparing 4a,5,9,10,11,12-hexahydro-6h-benzofuro[3a,3,2-ef][2]benzazepine derivatives and intermediates thereof |
-
1995
- 1995-09-21 GB GBGB9519267.0A patent/GB9519267D0/en active Pending
-
1996
- 1996-09-23 CA CA002230826A patent/CA2230826C/en not_active Expired - Lifetime
- 1996-09-23 EP EP96931169A patent/EP0854873B1/de not_active Expired - Lifetime
- 1996-09-23 DE DE69619685T patent/DE69619685T2/de not_active Expired - Lifetime
- 1996-09-23 AU AU69964/96A patent/AU714711B2/en not_active Expired
- 1996-09-23 WO PCT/GB1996/002334 patent/WO1997011077A1/en not_active Ceased
- 1996-09-23 PT PT96931169T patent/PT854873E/pt unknown
- 1996-09-23 ZA ZA9608028A patent/ZA968028B/xx unknown
- 1996-09-23 ES ES96931169T patent/ES2173316T3/es not_active Expired - Lifetime
- 1996-09-23 US US09/043,330 patent/US6093815A/en not_active Expired - Lifetime
- 1996-09-23 DK DK96931169T patent/DK0854873T3/da active
- 1996-09-23 AT AT96931169T patent/ATE214070T1/de active
-
2002
- 2002-11-25 CY CY0200063A patent/CY2301B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB9519267D0 (en) | 1995-11-22 |
| ZA968028B (en) | 1997-09-23 |
| ES2173316T3 (es) | 2002-10-16 |
| WO1997011077A1 (en) | 1997-03-27 |
| DE69619685T2 (de) | 2002-10-17 |
| PT854873E (pt) | 2002-08-30 |
| CY2301B1 (en) | 2003-07-04 |
| EP0854873A1 (de) | 1998-07-29 |
| US6093815A (en) | 2000-07-25 |
| AU714711B2 (en) | 2000-01-06 |
| DE69619685D1 (de) | 2002-04-11 |
| EP0854873B1 (de) | 2002-03-06 |
| ATE214070T1 (de) | 2002-03-15 |
| CA2230826C (en) | 2008-09-02 |
| CA2230826A1 (en) | 1997-03-27 |
| AU6996496A (en) | 1997-04-09 |
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