DK0856513T3 - Thalidomidanaloge forbindelser fra gruppen piperidin-2,6-dioner - Google Patents

Thalidomidanaloge forbindelser fra gruppen piperidin-2,6-dioner

Info

Publication number
DK0856513T3
DK0856513T3 DK98100259T DK98100259T DK0856513T3 DK 0856513 T3 DK0856513 T3 DK 0856513T3 DK 98100259 T DK98100259 T DK 98100259T DK 98100259 T DK98100259 T DK 98100259T DK 0856513 T3 DK0856513 T3 DK 0856513T3
Authority
DK
Denmark
Prior art keywords
piperidine
dione group
thalidomide analogues
thalidomide
analogues
Prior art date
Application number
DK98100259T
Other languages
English (en)
Inventor
Oswald Dr Zimmer
Werner Prof Dr Winter
Stephan Dr Wnendt
Kai Dr Zwingenberger
Kurt Prof Dr Eger
Uwe Teubert
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Application granted granted Critical
Publication of DK0856513T3 publication Critical patent/DK0856513T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
DK98100259T 1997-02-01 1998-01-09 Thalidomidanaloge forbindelser fra gruppen piperidin-2,6-dioner DK0856513T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19703763A DE19703763C1 (de) 1997-02-01 1997-02-01 Thalidomidanaloge Verbindungen aus der Klasse der Piperidin-2,6-Dione

Publications (1)

Publication Number Publication Date
DK0856513T3 true DK0856513T3 (da) 2005-12-27

Family

ID=7819009

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98100259T DK0856513T3 (da) 1997-02-01 1998-01-09 Thalidomidanaloge forbindelser fra gruppen piperidin-2,6-dioner

Country Status (27)

Country Link
US (1) US6110941A (da)
EP (1) EP0856513B1 (da)
JP (1) JPH10316675A (da)
KR (1) KR19980070959A (da)
CN (1) CN1109032C (da)
AR (1) AR010107A1 (da)
AT (1) ATE311381T1 (da)
AU (1) AU729733B2 (da)
BR (1) BR9800253A (da)
CA (1) CA2228385A1 (da)
CO (1) CO4940441A1 (da)
CZ (1) CZ27598A3 (da)
DE (2) DE19703763C1 (da)
DK (1) DK0856513T3 (da)
ES (1) ES2253790T3 (da)
HU (1) HUP9800146A3 (da)
IL (1) IL122372A (da)
NO (1) NO313007B1 (da)
NZ (1) NZ329325A (da)
PE (1) PE57499A1 (da)
PL (1) PL188700B1 (da)
RU (1) RU2184733C2 (da)
SI (1) SI0856513T1 (da)
SK (1) SK12498A3 (da)
UA (1) UA45408C2 (da)
UY (1) UY24870A1 (da)
ZA (1) ZA98749B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10013499A1 (de) * 1998-09-24 2001-09-27 Gruenenthal Gmbh Substituierte Benzamide
DE10002509A1 (de) 2000-01-21 2001-07-26 Gruenenthal Gmbh Substituierte Glutarimide
AU2002306596B2 (en) * 2001-02-27 2008-01-17 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Analogs of thalidomide as potential angiogenesis inhibitors
CN100398534C (zh) * 2003-09-15 2008-07-02 天津和美生物技术有限公司 合成酞胺哌啶酮及其衍生物的方法
US8952895B2 (en) 2011-06-03 2015-02-10 Apple Inc. Motion-based device operations
CN1867331B (zh) * 2003-09-17 2010-05-26 美国政府健康及人类服务部 作为TNF-α调节剂的沙利度胺类似物
WO2007120669A1 (en) * 2006-04-13 2007-10-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Tetrahalogenated compounds useful as inhibitors of angiogenesis
WO2012031603A2 (en) 2010-09-09 2012-03-15 Danish Medical Consults Aps Airway administration of angiogenesis inhibitors
US8927725B2 (en) 2011-12-02 2015-01-06 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Thio compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535721A1 (fr) * 1982-11-08 1984-05-11 Sanofi Sa Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives
US5356906A (en) * 1989-10-27 1994-10-18 The Du Pont Merck Pharmaceutical Company (N-phthalimidoalkyl) piperidines useful as treatments for psychosis
WO1992014455A1 (en) * 1991-02-14 1992-09-03 The Rockefeller University METHOD FOR CONTROLLING ABNORMAL CONCENTRATION TNF α IN HUMAN TISSUES
ATE231723T1 (de) * 1991-02-22 2003-02-15 Howard K Shapiro Verwendung von pharmazeutischen wirkstoffen zur behandlung von krankheitssymptomen neurologischer erkrankungen und etiologisch verwandter symptomenkomplexe
ATE146787T1 (de) * 1991-04-17 1997-01-15 Gruenenthal Gmbh Neue thalidomidderivate, ein verfahren zu deren herstellung sowie die verwendung derselben in arzneimitteln
US5356406A (en) * 1993-01-08 1994-10-18 Steven Schraga Adaptor to facilitate interconnection of medicine bottle and syringe
US5698579A (en) * 1993-07-02 1997-12-16 Celgene Corporation Cyclic amides
US5463063A (en) * 1993-07-02 1995-10-31 Celgene Corporation Ring closure of N-phthaloylglutamines
NZ333903A (en) * 1996-07-24 2000-02-28 Celgene Corp Substituted 2(2,6-dioxopiperidin-3-yl)phthalimides and -1oxoisoindolines and method of reducing TNF-alpha levels in a mammal

Also Published As

Publication number Publication date
CA2228385A1 (en) 1998-08-01
NO313007B1 (no) 2002-07-29
ZA98749B (en) 1998-08-03
CO4940441A1 (es) 2000-07-24
SK12498A3 (en) 1998-08-05
AU729733B2 (en) 2001-02-08
IL122372A0 (en) 1998-06-15
IL122372A (en) 2002-12-01
BR9800253A (pt) 1999-08-24
AR010107A1 (es) 2000-05-17
SI0856513T1 (sl) 2006-02-28
AU5284098A (en) 1998-08-06
JPH10316675A (ja) 1998-12-02
DE19703763C1 (de) 1998-10-01
NO980416L (no) 1998-08-03
EP0856513B1 (de) 2005-11-30
ATE311381T1 (de) 2005-12-15
CN1190096A (zh) 1998-08-12
UY24870A1 (es) 2001-05-31
NO980416D0 (no) 1998-01-30
RU2184733C2 (ru) 2002-07-10
US6110941A (en) 2000-08-29
UA45408C2 (uk) 2002-04-15
EP0856513A3 (de) 1998-09-23
DE59813233D1 (de) 2006-01-05
PL324588A1 (en) 1998-08-03
EP0856513A2 (de) 1998-08-05
CN1109032C (zh) 2003-05-21
HUP9800146A2 (hu) 1998-12-28
NZ329325A (en) 1998-07-28
ES2253790T3 (es) 2006-06-01
HUP9800146A3 (en) 2000-06-28
KR19980070959A (ko) 1998-10-26
PL188700B1 (pl) 2005-03-31
CZ27598A3 (cs) 1998-08-12
PE57499A1 (es) 1999-07-10
HU9800146D0 (en) 1998-03-30
HK1015363A1 (en) 1999-10-15

Similar Documents

Publication Publication Date Title
IS5941A (is) Píperidín sem CCR5 stillar
NO20015365D0 (no) Piperidinderivater som er anvendbare som CCR5-antagonister
ID17259A (id) Fluorina mengandung turunan piperidina 1,4-disubtitusikan
FI970523A7 (fi) (Atsetidin-1-yylialkyyli)laktaamit takykiniiniantagonisteina
NO990551D0 (no) Piperidin- og piperazinderivater, og deres anvendelse som muskarine antagonister
FI952064A7 (fi) Takykiniinireseptoriantagonisteja, joilla ei ole peptidyylirakennetta
ATE278695T1 (de) Piperidinderivate
ATE386720T1 (de) Piperidin ccr-3 rezeptor-hemmer
DE69707782D1 (de) 4-Hydroxypiperidinderivate
NO20001609L (no) Aminoterminert trunkerte RANTES som kjemokinantagonister
NO982651L (no) 3-Azetidinylalkylpiperidiner eller -pyrrolidiner som takykininantagonister
DK0856513T3 (da) Thalidomidanaloge forbindelser fra gruppen piperidin-2,6-dioner
NO993460D0 (no) Paroxetine-preparater
FR2758327B1 (fr) Nouvelles arylpiperazines derivees de piperidine
ID22838A (id) Oksazolidina sebagai antagonis 5-ht2a
FI955498L (fi) Nipekotiinihappojohdannaisia hyytymistä estävinä aineina
DK1049674T3 (da) Fremgangsmåde til fremstilling af (-) cis-3-hydroxy-1-methyl-4-(2,4,6-trimethoxyphenyl) -piperidin
NO992302L (no) Piperidin-derivater
ATE205830T1 (de) 4-hydroxypiperidinderivate
NO995782D0 (no) Kvarternaere ammoniumforbindelser som tachykinin-antagonister
HUP9904035A3 (en) Modified crystalline form of the r-(-)-n-(4,4-di(3-methylthien-2-yl)but-3-enyl)-nipecotic acid hydrochloride
DK1202966T3 (da) Piperidinalkoholer
NO20002575D0 (no) Substituerte oksimer som neurokininantagonister
DK0882044T3 (da) 1,4-dihydropyridinforbindelser som bradykinin-antagonister
ATE355285T1 (de) In 3-position heterocyclisch substituierte piperidin-2,6-dione