DK0859615T3 - Carbostyrilderivat til helbredelse af ophthalmologiske sygdomme - Google Patents

Carbostyrilderivat til helbredelse af ophthalmologiske sygdomme

Info

Publication number
DK0859615T3
DK0859615T3 DK96932058T DK96932058T DK0859615T3 DK 0859615 T3 DK0859615 T3 DK 0859615T3 DK 96932058 T DK96932058 T DK 96932058T DK 96932058 T DK96932058 T DK 96932058T DK 0859615 T3 DK0859615 T3 DK 0859615T3
Authority
DK
Denmark
Prior art keywords
cure
carbostyril derivative
ophthalmological diseases
ophthalmological
diseases
Prior art date
Application number
DK96932058T
Other languages
Danish (da)
English (en)
Inventor
Hiroki Urashima
Yasuhiro Takeji
Hisashi Shinohara
Shigeki Fujisawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of DK0859615T3 publication Critical patent/DK0859615T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4704—2-Quinolinones, e.g. carbostyril
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK96932058T 1995-10-12 1996-10-01 Carbostyrilderivat til helbredelse af ophthalmologiske sygdomme DK0859615T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP26389695 1995-10-12
JP5733796 1996-03-14
PCT/JP1996/002850 WO1997013515A1 (en) 1995-10-12 1996-10-01 Carbostyril derivative for curing ophthalmological diseases

Publications (1)

Publication Number Publication Date
DK0859615T3 true DK0859615T3 (da) 2001-09-03

Family

ID=26398366

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96932058T DK0859615T3 (da) 1995-10-12 1996-10-01 Carbostyrilderivat til helbredelse af ophthalmologiske sygdomme

Country Status (16)

Country Link
US (1) US6060486A (de)
EP (1) EP0859615B1 (de)
KR (1) KR100281865B1 (de)
CN (1) CN1132580C (de)
AR (3) AR004214A1 (de)
AT (1) ATE201992T1 (de)
AU (1) AU709734B2 (de)
CA (1) CA2234247C (de)
DE (1) DE69613386T2 (de)
DK (1) DK0859615T3 (de)
ES (1) ES2159043T3 (de)
GR (1) GR3036457T3 (de)
MX (1) MX9802817A (de)
PT (1) PT859615E (de)
TW (1) TW446702B (de)
WO (1) WO1997013515A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3093661B2 (ja) 1995-10-12 2000-10-03 大塚製薬株式会社 眼疾患治療剤
US6506412B2 (en) 2000-11-29 2003-01-14 Sciencebased Health Treatment of dry eye syndrome
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
DE10133870A1 (de) * 2001-07-12 2003-02-06 Chris P Lohmann Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge
KR100907407B1 (ko) * 2002-09-28 2009-07-10 주식회사 케이티 대량 메시지 동보 전송을 위한 메시지 예약 및 전송 방법
ATE373502T1 (de) * 2003-07-30 2007-10-15 Otsuka Pharma Co Ltd Carbostyril-derivative zur beschleunigten speichelabsonderung
WO2005046700A1 (ja) * 2003-11-14 2005-05-26 Senju Pharmaceutical Co., Ltd. アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤
TWI340650B (en) 2004-01-21 2011-04-21 Otsuka Pharma Co Ltd Amine saly of carbostyril derivative
CN101005834A (zh) 2004-08-27 2007-07-25 千寿制药株式会社 干眼症治疗用滴眼液
TWI363626B (en) * 2004-11-15 2012-05-11 Otsuka Pharma Co Ltd Aqueous ophthalmic suspension of crystalline rebamipide
TW200808375A (en) * 2006-05-12 2008-02-16 Otsuka Pharma Co Ltd Hydrogel suspension and manufacturing process thereof
TWI415629B (zh) * 2006-10-26 2013-11-21 Otsuka Pharma Co Ltd 含有瑞巴匹特之水性醫藥懸浮物及其製造方法
RU2331408C1 (ru) * 2007-05-31 2008-08-20 Государственное образовательное учреждение высшего профессионального образования "БАШКИРСКИЙ ГОСУДАРСТВЕННЫЙ МЕДИЦИНСКИЙ УНИВЕРСИТЕТ Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО БГМУ РОСЗДРАВА) Глазная мазь
US20110124682A1 (en) * 2008-06-19 2011-05-26 Sumida Shun-Ichiro Pharmaceutical composition comprising rebamipide
CN103476753B (zh) 2011-02-25 2015-12-09 诺弗米克斯有限公司 新的瑞巴派特复合物和共晶体
TW201322982A (zh) 2011-11-01 2013-06-16 Otsuka Pharma Co Ltd 用於治療前眼疾病之藥劑，該藥劑包含瑞巴派特及眼淚保持劑
KR101692578B1 (ko) * 2013-04-18 2017-01-03 삼진제약주식회사 레바미피드 또는 이의 전구체를 포함하는 안구건조증의 예방 또는 치료를 위한 경구용 약제학적 조성물
US10004395B2 (en) * 2014-05-02 2018-06-26 Massachusetts Eye And Ear Infirmary Grading corneal fluorescein staining
KR102307958B1 (ko) 2015-10-01 2021-10-05 삼진제약주식회사 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법
KR20170039347A (ko) 2015-10-01 2017-04-11 삼진제약주식회사 레바미피드를 함유하는 신규한 점안 조성물 및 이의 제조방법
EP3592339B1 (de) 2017-03-05 2025-04-30 Resdevco Research and Development Co. Ltd. Augentropfen zur behandlung von reizungen oder schädigungen aufgrund des sjögren-syndroms
KR102615076B1 (ko) 2021-07-14 2023-12-19 대우제약 주식회사 안정한 레바미피드 점안제의 대용량 제조 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI80022C (fi) * 1982-07-05 1990-04-10 Otsuka Pharma Co Ltd Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart karbostyrilderivat.
JPH0713138B2 (ja) * 1986-07-30 1995-02-15 保土谷化学工業株式会社 ポリテトラメチレンエ−テルグリコ−ルの製法
DE69207560T2 (de) * 1991-06-07 1996-06-27 Otsuka Pharma Co Ltd Antidiabetikum
TW227558B (de) * 1992-05-14 1994-08-01 Otsuka Pharma Co Ltd
WO1994021612A1 (en) * 1993-03-18 1994-09-29 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives as matrix metalloproteinases inhibitors
CA2150546C (en) * 1993-10-21 2004-11-09 Takahide Matsuda Agent for inhibiting production of interleukin-8
KR970704439A (ko) * 1994-08-10 1997-09-06 오쓰카 아키히코 눈의 염증 및/또는 상처의 예방 및 치료 방법(Method of preventing and treating ophthalmic inflammation and/or wound)

Also Published As

Publication number Publication date
ES2159043T3 (es) 2001-09-16
GR3036457T3 (en) 2001-11-30
KR19990064187A (ko) 1999-07-26
MX9802817A (es) 1998-09-30
DE69613386D1 (de) 2001-07-19
US6060486A (en) 2000-05-09
EP0859615B1 (de) 2001-06-13
ATE201992T1 (de) 2001-06-15
TW446702B (en) 2001-07-21
DE69613386T2 (de) 2002-05-23
KR100281865B1 (ko) 2001-02-15
AU7097596A (en) 1997-04-30
AR070051A2 (es) 2010-03-10
EP0859615A1 (de) 1998-08-26
CN1132580C (zh) 2003-12-31
CA2234247C (en) 2005-05-10
AR004214A1 (es) 1998-11-04
CN1202108A (zh) 1998-12-16
AR055393A2 (es) 2007-08-22
WO1997013515A1 (en) 1997-04-17
CA2234247A1 (en) 1997-04-17
AU709734B2 (en) 1999-09-02
PT859615E (pt) 2001-09-28

Similar Documents

Publication Publication Date Title
DK0730864T3 (da) Lægemiddel til behandling af inflammatoriske hjertesygdomme
NO965377L (no) Indolinonforbindelser for behandling av sykdommer
DK0785792T3 (da) Præparat til behandling af ovariale af østrogen afhængige sygdomme
DK1028954T3 (da) Substituerede imidazoler egnede til behandling af inflammatoriske sygdomme
DK0841946T4 (da) Metoder til behandling af allergisk astma
NO20010556L (no) Fremgangsmate for oftalmisk administrering
DK0966447T3 (da) Anvendelige små molekyler til behandling af betændelsessygdomme
DK0941103T3 (da) Farmaceutisk præparat til behandling af diabetes
FI952721L (fi) Aine maksa-sappi-sairauksien hoitamiseksi
NO910395L (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 4-isoxazolcarboxamidderivater.
NO985066D0 (no) Terapeutisk behandling for VEGF-relaterte sykdommer
GR3036457T3 (en) Carbostyril derivative for curing ophthalmological diseases
NO995251D0 (no) FremgangsmÕte for administrering av haloterapi
DK0979079T3 (da) Anvendelse af tetrahydropyridinderivater til fremstilling af lægemidler til behandling af sygdomme, der medförer en demyelinisering
FI933902A7 (fi) Substituoidut sykloheksaanijohdannaiset sairauksien hoitamiseksi
NO953254D0 (no) Substituerte azolonderivater for behandling av sykdommer forårsaket av helikobakter
DK0768310T3 (da) Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater
PT983275E (pt) Novos derivados do triptolido vantajosos para o tratamento de doencas autoimunes
DK0877738T3 (da) Fremgangsmåde til fremstilling af phenylimidazolidinderivater
FI971527L (fi) Indolijohdannaisten käyttö erilaisten sairauksien hoitoon
DE69618560D1 (de) Medikament gegen ophthalmische erkrankungen
NO991733D0 (no) FremgangsmÕte for fremstilling av et IgM-preparat for intraven°s administrering
NO20024060D0 (no) Fremgangsmåte for fremstilling av et oksazolyletanolderivat
NO991734D0 (no) Pyrazolinoner for behandling av potensforstyrrelser
EE9700235A (et) Benseenamiidid neurodegeneratiivsete haiguste ravimiseks