DK0861235T3 - Substituerede benzylaminopiperidinforbindelser - Google Patents

Substituerede benzylaminopiperidinforbindelser

Info

Publication number
DK0861235T3
DK0861235T3 DK96914375T DK96914375T DK0861235T3 DK 0861235 T3 DK0861235 T3 DK 0861235T3 DK 96914375 T DK96914375 T DK 96914375T DK 96914375 T DK96914375 T DK 96914375T DK 0861235 T3 DK0861235 T3 DK 0861235T3
Authority
DK
Denmark
Prior art keywords
compounds
substituted
substituted benzylaminopiperidine
benzylaminopiperidine compounds
benzylaminopiperidine
Prior art date
Application number
DK96914375T
Other languages
English (en)
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0861235T3 publication Critical patent/DK0861235T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK96914375T 1995-08-24 1996-06-10 Substituerede benzylaminopiperidinforbindelser DK0861235T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24
PCT/IB1996/000572 WO1997008144A1 (en) 1995-08-24 1996-06-10 Substituted benzylaminopiperidine compounds

Publications (1)

Publication Number Publication Date
DK0861235T3 true DK0861235T3 (da) 2001-12-27

Family

ID=11004362

Family Applications (2)

Application Number Title Priority Date Filing Date
DK96914375T DK0861235T3 (da) 1995-08-24 1996-06-10 Substituerede benzylaminopiperidinforbindelser
DK01108350T DK1114817T3 (da) 1995-08-24 1996-06-10 Substituerede benzylaminopiperidinforbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01108350T DK1114817T3 (da) 1995-08-24 1996-06-10 Substituerede benzylaminopiperidinforbindelser

Country Status (41)

Country Link
US (1) US6506775B1 (da)
EP (2) EP1114817B1 (da)
JP (1) JP3084069B2 (da)
KR (1) KR100288673B1 (da)
CN (1) CN1153764C (da)
AP (1) AP643A (da)
AR (1) AR006305A1 (da)
AT (2) ATE258166T1 (da)
AU (1) AU702698B2 (da)
BG (1) BG64126B1 (da)
BR (1) BR9609989A (da)
CA (1) CA2227814C (da)
CO (1) CO4480738A1 (da)
CZ (1) CZ297543B6 (da)
DE (2) DE69616817T2 (da)
DK (2) DK0861235T3 (da)
DZ (1) DZ2086A1 (da)
ES (2) ES2211684T3 (da)
HR (1) HRP960386B1 (da)
HU (1) HU225480B1 (da)
IL (1) IL119078A (da)
IS (1) IS1947B (da)
MA (1) MA23961A1 (da)
MX (1) MX9801467A (da)
MY (1) MY114800A (da)
NO (1) NO310720B1 (da)
NZ (1) NZ308207A (da)
OA (1) OA10666A (da)
PE (2) PE20010700A1 (da)
PL (1) PL186773B1 (da)
PT (2) PT1114817E (da)
RO (1) RO119299B1 (da)
RU (1) RU2152930C2 (da)
SI (2) SI1114817T1 (da)
SK (1) SK282925B6 (da)
TN (1) TNSN96107A1 (da)
TR (1) TR199800300T1 (da)
TW (1) TW340842B (da)
UA (1) UA48981C2 (da)
WO (1) WO1997008144A1 (da)
YU (1) YU49122B (da)

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MX9706196A (es) * 1996-08-14 1998-02-28 Pfizer Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p.
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en) 1999-02-10 2004-08-17 Eli Lilly And Company 5-HT1f agonist
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RS49964B (sr) 1999-05-17 2008-09-29 Pfizer Products Inc., Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
DE60001736T2 (de) * 1999-05-21 2003-09-18 Pfizer Prod Inc 1-trifluorotmethyl-4-hydroxy-7-piperidinyl-aminomethylchroman-derivate
ATE257477T1 (de) * 1999-10-18 2004-01-15 Pfizer Prod Inc Verfahren zur herstellung von zyklischen piperidinylaminomethyl-trifluoromethyl- etherderivaten
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のｎｋ−１レセプターアンタゴニスト及びエレトリプタン
US7163949B1 (en) 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
MXPA02004330A (es) 1999-11-03 2004-07-30 Albany Molecular Res Inc Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
PE20020291A1 (es) * 2000-08-21 2002-04-17 Hoffmann La Roche Profarmacos para ligandos del receptor nmda
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (en) * 2000-09-28 2003-03-26 Pfizer Products Inc. Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
MXPA05011223A (es) 2003-04-18 2006-01-26 Lilly Co Eli Compuestos de (piperidiniloxi)fenilo, (piperidiniloxi)piridinilo, (piperidinilsulfanil)fenilo y (piperidinilsulfanil)piridinilo como agonistas 5-htif.
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UA91341C2 (ru) 2004-07-15 2010-07-26 Амр Текнолоджи, Інк. Арил- и гетероарилзамещенные тетрагидроизохинолины и их применение для блокирования обратного захвата норэпинефрина, допамина и серотонина
WO2006123182A2 (en) 2005-05-17 2006-11-23 Merck Sharp & Dohme Limited Cyclohexyl sulphones for treatment of cancer
UA95454C2 (uk) 2005-07-15 2011-08-10 Амр Текнолоджи, Інк. Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну
BRPI0616463A2 (pt) 2005-09-29 2011-06-21 Merck & Co Inc composto, composição farmacêutica, e, uso de um composto
SE529246C2 (sv) * 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
JP5489333B2 (ja) 2006-09-22 2014-05-14 メルク・シャープ・アンド・ドーム・コーポレーション 脂肪酸合成阻害剤を用いた治療の方法
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
AR064777A1 (es) 2007-01-10 2009-04-22 Inst Di Reserche D Biolog Mole Indazoles sustituidos con amida como inhibidores de poli (adp- ribosa) polimerasa (parp)
CA2682727C (en) 2007-04-02 2016-03-22 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
EP3103791B1 (en) 2007-06-27 2018-01-31 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
CN102014631A (zh) 2008-03-03 2011-04-13 泰格尔医药科技公司 酪氨酸激酶抑制剂
US7951822B2 (en) 2008-03-31 2011-05-31 Kowa Company, Ltd. 1,3-dihydroisobenzofuran derivatives
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
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TW201429969A (zh) 2012-12-20 2014-08-01 Merck Sharp & Dohme 作爲ｈｄｍ２抑制劑之經取代咪唑吡啶
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US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
RU2105001C1 (ru) * 1991-03-26 1998-02-20 Пфайзер Инк. Способ получения замещенных 3-аминопиперидинов
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Also Published As

Publication number Publication date
CO4480738A1 (es) 1997-07-09
AR006305A1 (es) 1999-08-25
ES2163017T3 (es) 2002-01-16
NO310720B1 (no) 2001-08-20
DK1114817T3 (da) 2004-04-26
DE69631390D1 (de) 2004-02-26
HU225480B1 (en) 2006-12-28
US6506775B1 (en) 2003-01-14
MY114800A (en) 2003-01-31
KR19990044077A (ko) 1999-06-25
SI0861235T1 (en) 2002-04-30
AP643A (en) 1998-04-24
JPH10510554A (ja) 1998-10-13
HK1014935A1 (en) 1999-10-08
CA2227814A1 (en) 1997-03-06
EP1114817A1 (en) 2001-07-11
EP0861235A1 (en) 1998-09-02
RU2152930C2 (ru) 2000-07-20
PT1114817E (pt) 2004-05-31
CA2227814C (en) 2002-12-31
OA10666A (en) 2002-11-25
YU49122B (sh) 2004-03-12
PE1398A1 (es) 1998-02-27
EP0861235B1 (en) 2001-11-07
BG102288A (en) 1998-09-30
TR199800300T1 (xx) 1998-06-22
SK282925B6 (sk) 2003-01-09
PL325332A1 (en) 1998-07-20
IS4644A (is) 1997-12-30
AP9600850A0 (en) 1996-10-31
AU702698B2 (en) 1999-03-04
HRP960386B1 (en) 2002-04-30
BR9609989A (pt) 1999-07-06
AU5776996A (en) 1997-03-19
DZ2086A1 (fr) 2002-07-22
EP1114817B1 (en) 2004-01-21
DE69616817T2 (de) 2002-04-04
ATE258166T1 (de) 2004-02-15
HUP9901159A3 (en) 2000-05-29
DE69631390T2 (de) 2004-11-25
WO1997008144A1 (en) 1997-03-06
JP3084069B2 (ja) 2000-09-04
IS1947B (is) 2004-10-13
YU47896A (sh) 1998-12-23
NO980751L (no) 1998-02-23
IL119078A (en) 2003-11-23
CN1193961A (zh) 1998-09-23
KR100288673B1 (ko) 2001-05-02
MA23961A1 (fr) 1997-04-01
PT861235E (pt) 2002-03-28
IL119078A0 (en) 1996-11-14
TW340842B (en) 1998-09-21
RO119299B1 (ro) 2004-07-30
NZ308207A (en) 1998-07-28
CZ297543B6 (cs) 2007-02-07
ATE208377T1 (de) 2001-11-15
CN1153764C (zh) 2004-06-16
CZ52198A3 (cs) 1999-01-13
NO980751D0 (no) 1998-02-23
ES2211684T3 (es) 2004-07-16
UA48981C2 (uk) 2002-09-16
SI1114817T1 (en) 2004-06-30
PL186773B1 (pl) 2004-02-27
DE69616817D1 (de) 2001-12-13
MX9801467A (es) 1998-05-31
TNSN96107A1 (fr) 2005-03-15
BG64126B1 (bg) 2004-01-30
HRP960386A2 (en) 1998-04-30
HUP9901159A2 (hu) 1999-07-28
SK20798A3 (en) 1999-03-12
PE20010700A1 (es) 2001-07-09

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