DK0866848T3 - Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme - Google Patents

Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme

Info

Publication number
DK0866848T3
DK0866848T3 DK96939719T DK96939719T DK0866848T3 DK 0866848 T3 DK0866848 T3 DK 0866848T3 DK 96939719 T DK96939719 T DK 96939719T DK 96939719 T DK96939719 T DK 96939719T DK 0866848 T3 DK0866848 T3 DK 0866848T3
Authority
DK
Denmark
Prior art keywords
methods
hosts
recombinant proteins
producing
neurospora
Prior art date
Application number
DK96939719T
Other languages
Danish (da)
English (en)
Inventor
W Dorsey Stuart
Original Assignee
Univ Hawaii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Hawaii filed Critical Univ Hawaii
Application granted granted Critical
Publication of DK0866848T3 publication Critical patent/DK0866848T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungi isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Botany (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK96939719T 1995-12-15 1996-11-12 Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme DK0866848T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/573,020 US5776730A (en) 1995-12-15 1995-12-15 Neurospora hosts for the production of recombinant proteins, and methods for producing same
PCT/US1996/018348 WO1997022687A1 (en) 1995-12-15 1996-11-12 Improved neurospora hosts for the production of recombinant proteins, and methods for producing the same

Publications (1)

Publication Number Publication Date
DK0866848T3 true DK0866848T3 (da) 2007-05-21

Family

ID=24290328

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96939719T DK0866848T3 (da) 1995-12-15 1996-11-12 Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme

Country Status (11)

Country Link
US (1) US5776730A (de)
EP (1) EP0866848B1 (de)
JP (1) JPH11510065A (de)
AT (1) ATE354636T1 (de)
AU (1) AU721592B2 (de)
CA (1) CA2240149C (de)
DE (1) DE69636922T2 (de)
DK (1) DK0866848T3 (de)
ES (1) ES2283006T3 (de)
PT (1) PT866848E (de)
WO (1) WO1997022687A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7883872B2 (en) * 1996-10-10 2011-02-08 Dyadic International (Usa), Inc. Construction of highly efficient cellulase compositions for enzymatic hydrolysis of cellulose
US5811381A (en) * 1996-10-10 1998-09-22 Mark A. Emalfarb Cellulase compositions and methods of use
ES2237159T3 (es) * 1998-10-06 2005-07-16 Mark Aaron Emalfarb Sistema de transformacion en el campo de los hongos micoticos filamentosos en chrysosporium.
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
US8603824B2 (en) 2004-07-26 2013-12-10 Pfenex, Inc. Process for improved protein expression by strain engineering
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
EP2505651A3 (de) 2006-12-10 2013-01-09 Dyadic International, Inc. Pilzisolate mit reduzierter Proteaseaktivität
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法
CA2736661A1 (en) * 2007-09-07 2009-03-12 Dyadic International, Inc. Novel fungal enzymes
DE102008013689A1 (de) * 2008-03-11 2009-09-17 Tesa Se Folienanordnung
DK2800809T3 (en) 2012-01-05 2018-05-22 Glykos Finland Oy PROTEASE-DEFECTED FILAMENTARY FUNGAL CELLS AND PROCEDURES FOR USE THEREOF
WO2013174927A1 (en) 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production of fucosylated glycoproteins
US10435731B2 (en) 2013-07-10 2019-10-08 Glykos Finland Oy Multiple proteases deficient filamentous fungal cells and methods of use thereof
SG11201700446XA (en) 2014-07-21 2017-02-27 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486533A (en) * 1982-09-02 1984-12-04 St. Louis University Filamentous fungi functional replicating extrachromosomal element
US4816405A (en) * 1984-10-24 1989-03-28 The Regents Of The University Of California Vectors for transformation by ascomycetes
US4885249A (en) * 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
US4935349A (en) * 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
US5179003A (en) * 1988-01-05 1993-01-12 Boehringer Mannheim Gmbh Process for the production of proteins or protein-containing gene products
ES2281079T3 (es) * 1995-03-20 2007-09-16 Novozymes A/S Celula huesped que expresa niveles reducidos de metaloproteasa y metodos de utilizacion de la celula huesped para la produccion de proteinas.
AU7112796A (en) * 1995-09-27 1997-04-17 Chiron Corporation Method of making a protease deficient host

Also Published As

Publication number Publication date
CA2240149A1 (en) 1997-06-26
PT866848E (pt) 2007-03-30
EP0866848A4 (de) 2000-03-15
ES2283006T3 (es) 2007-10-16
DE69636922T2 (de) 2007-12-06
EP0866848B1 (de) 2007-02-21
WO1997022687A1 (en) 1997-06-26
ATE354636T1 (de) 2007-03-15
CA2240149C (en) 2009-06-30
AU7681196A (en) 1997-07-14
AU721592B2 (en) 2000-07-06
DE69636922D1 (de) 2007-04-05
JPH11510065A (ja) 1999-09-07
EP0866848A1 (de) 1998-09-30
US5776730A (en) 1998-07-07

Similar Documents

Publication Publication Date Title
DK0866848T3 (da) Forbedrede neurospora-værter til fremstilling af rekombinante proteiner og fremgangsmåde til fremstilling af samme
MXPA02004666A (es) Gelatinas recombinantes.
IL139478A0 (en) Hybrid protein
EP1644514A4 (de) Temperaturstabile amylase-polypeptide, für diese polypeptide codierende nukleinsäuren und verwendungen davon
ATE317904T1 (de) Überexpression von phytase in hefesystemen
TR200000547T2 (tr) Lignin biyosentezi için enzimleri kodlayan genler ve bunların kullanımı.
DE69942459D1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
DE69823046D1 (de) Praktische in vitro sialylierung von rekombinanten glykpproteinen
BR0012759A (pt) Neurotoxinas recombinantes ativáveis
HUT77049A (hu) Katepszin-02-fehérjék, -nukleinsavak és -ellenanyagok
DE69638077D1 (de) Bakterielle Produktion von Interferon-beta Polypeptiden
DK1276874T3 (da) Kloning og ekspression af en syreresistent ekstracellulær lipase fra yarrowia lipolytica
DE60331224D1 (de) Subtilisin-carlsberg-proteine mit verminderter immunogenität
DE60025467D1 (de) Oxalacetat-hydrolase defiziente fungale wirtszellen
ATE309356T1 (de) Konstruierte fluoreszenzproteine mit langen wellenlängen
ATE320485T1 (de) Mutierte furin polypeptide, welche verbesserte eigenschaften aufweisen
ATE285474T1 (de) Haemophilus adhäsionsproteinen
DE69737457D1 (de) O-fukosyltransferase
TR199700688A2 (xx) �yile�tirilmi� �zelliklere sahip aprotinin varyantlar�.
DK0414297T3 (da) Effektiv fremstilling af mutantproteaser
DK0826054T3 (da) Ekspression af glycosyltransferase i Aspergillus
EP1200476A4 (de) Antitumorantikörper, proteine und deren verwendung
WO2002090500A3 (en) Novel human proteins, polynucleotides encoding them and methods of using the same
WO2001085924A3 (en) MODULATION OF η-SECRETASE ACTIVITY
AU2003287945A8 (en) Mutant protein and refolding method