DK0868525T3 - Fremgangsmåde til fremstilling af mellemprodukter til syntese af antifungale midler - Google Patents

Fremgangsmåde til fremstilling af mellemprodukter til syntese af antifungale midler

Info

Publication number: DK0868525T3
Authority: DK; Denmark
Prior art keywords: intermediates; synthesis; preparation; antifungal agents; effective amount
Prior art date: 1995-12-20

Application number

DK96944241T

Other languages

Danish (da)

English (en)

Inventor

Christopher M Nielsen

Anantha Sudhakar

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-20

Filing date

1996-12-18

Publication date

2003-04-07

1996-12-18 Application filed by Schering Corp filed Critical Schering Corp

2003-04-07 Application granted granted Critical

2003-04-07 Publication of DK0868525T3 publication Critical patent/DK0868525T3/da

Links

238000000034 method Methods 0.000 title abstract 3
229940121375 antifungal agent Drugs 0.000 title 1
239000003429 antifungal agent Substances 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
239000000543 intermediate Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
102000004882 Lipase Human genes 0.000 abstract 1
108090001060 Lipase Proteins 0.000 abstract 1
150000002009 diols Chemical class 0.000 abstract 1
-1 hydroxy ester Chemical class 0.000 abstract 1
LSACYLWPPQLVSM-UHFFFAOYSA-N isobutyric acid anhydride Chemical compound CC(C)C(=O)OC(=O)C(C)C LSACYLWPPQLVSM-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/65—Halogen-containing esters of unsaturated acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Casting Devices For Molds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK96944241T 1995-12-20 1996-12-18 Fremgangsmåde til fremstilling af mellemprodukter til syntese af antifungale midler DK0868525T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US57533495A	1995-12-20	1995-12-20
PCT/US1996/019423 WO1997022710A1 (en)	1995-12-20	1996-12-18	Process for preparing intermediates for the synthesis of antifungal agents

Publications (1)

Publication Number	Publication Date
DK0868525T3 true DK0868525T3 (da)	2003-04-07

Family

ID=24299896

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96944241T DK0868525T3 (da)	1995-12-20	1996-12-18	Fremgangsmåde til fremstilling af mellemprodukter til syntese af antifungale midler

Country Status (20)

Country	Link
EP (1)	EP0868525B1 (de)
JP (4)	JP2000501946A (de)
KR (1)	KR100456181B1 (de)
CN (1)	CN1090240C (de)
AT (1)	ATE232906T1 (de)
AU (1)	AU716642B2 (de)
BR (1)	BR9612082A (de)
CA (1)	CA2240408C (de)
CZ (1)	CZ292649B6 (de)
DE (1)	DE69626308T2 (de)
DK (1)	DK0868525T3 (de)
ES (1)	ES2187684T3 (de)
HU (1)	HU225765B1 (de)
IL (2)	IL125005A0 (de)
MX (1)	MX9804958A (de)
NO (1)	NO320154B1 (de)
NZ (1)	NZ325566A (de)
PL (1)	PL185775B1 (de)
SK (1)	SK284149B6 (de)
WO (1)	WO1997022710A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2004031394A2 (en)	2002-10-03	2004-04-15	Wyeth Holdings Corporation	Process for preparing monoprotected diols from symmetric diols
US9206146B2 (en)	2010-05-19	2015-12-08	Sandoz Ag	Purification of posaconazole and of posaconazole intermediates
RU2580318C2 (ru)	2010-05-19	2016-04-10	Сандоз Аг	Получение промежуточных продуктов для синтеза позаконазола
EP2571871B1 (de)	2010-05-19	2017-06-21	Sandoz AG	Verfahren zur Herstellung von chiralen Triazolonen
US9199919B2 (en)	2010-05-19	2015-12-01	Sandoz Ag	Process for the preparation of chiral hydrazides
CN108329303A (zh)	2011-06-16	2018-07-27	桑多斯股份公司	制备手性化合物的方法
EP2789610A1 (de)	2013-04-10	2014-10-15	Sandoz Ag	Reinigung von Posaconazol-Zwischenprodukten
CN108727196A (zh) *	2018-07-23	2018-11-02	安徽华星化工有限公司	一种生产2-甲基-4-氯苯氧乙酸的酯类的方法
CN115448912B (zh) *	2022-10-12	2023-09-12	四川澄华生物科技有限公司	泊沙康唑中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993022451A1 (en) *	1992-05-01	1993-11-11	Cognis, Inc.	PROCESS OF PREPARING ENRICHED ENANTIOMERS OF GLYCEROL CARBONATE AND DERIVATIVES THEREOF FOR SYNTHESIS OF β-BLOCKERS
US5403937A (en) *	1993-04-30	1995-04-04	Schering Corporation	Process for preparing intermediates for the synthesis of antifungal agents
US5442093A (en) *	1994-05-09	1995-08-15	Schering Corporation	Process for preparing intermediates for the synthesis of antifungal agents

1996
- 1996-12-18 WO PCT/US1996/019423 patent/WO1997022710A1/en not_active Ceased
- 1996-12-18 PL PL96327456A patent/PL185775B1/pl unknown
- 1996-12-18 DE DE69626308T patent/DE69626308T2/de not_active Expired - Lifetime
- 1996-12-18 IL IL12500596A patent/IL125005A0/xx unknown
- 1996-12-18 CN CN96199938A patent/CN1090240C/zh not_active Expired - Fee Related
- 1996-12-18 HU HU9902113A patent/HU225765B1/hu not_active IP Right Cessation
- 1996-12-18 BR BR9612082A patent/BR9612082A/pt not_active Application Discontinuation
- 1996-12-18 KR KR10-1998-0704645A patent/KR100456181B1/ko not_active Expired - Fee Related
- 1996-12-18 CZ CZ19981916A patent/CZ292649B6/cs not_active IP Right Cessation
- 1996-12-18 JP JP9522850A patent/JP2000501946A/ja not_active Withdrawn
- 1996-12-18 EP EP96944241A patent/EP0868525B1/de not_active Expired - Lifetime
- 1996-12-18 DK DK96944241T patent/DK0868525T3/da active
- 1996-12-18 AU AU14101/97A patent/AU716642B2/en not_active Ceased
- 1996-12-18 CA CA002240408A patent/CA2240408C/en not_active Expired - Fee Related
- 1996-12-18 NZ NZ325566A patent/NZ325566A/xx not_active IP Right Cessation
- 1996-12-18 SK SK864-98A patent/SK284149B6/sk not_active IP Right Cessation
- 1996-12-18 ES ES96944241T patent/ES2187684T3/es not_active Expired - Lifetime
- 1996-12-18 AT AT96944241T patent/ATE232906T1/de active
1998
- 1998-06-18 IL IL125005A patent/IL125005A/en not_active IP Right Cessation
- 1998-06-19 NO NO19982880A patent/NO320154B1/no not_active IP Right Cessation
- 1998-06-19 MX MX9804958A patent/MX9804958A/es not_active IP Right Cessation
2006
- 2006-08-18 JP JP2006223570A patent/JP2007020573A/ja not_active Withdrawn
2008
- 2008-05-29 JP JP2008141693A patent/JP4906785B2/ja not_active Expired - Fee Related
2011
- 2011-04-20 JP JP2011094504A patent/JP2011139715A/ja active Pending

Also Published As

Publication number	Publication date
CN1209171A (zh)	1999-02-24
SK284149B6 (sk)	2004-10-05
CA2240408A1 (en)	1997-06-26
JP2000501946A (ja)	2000-02-22
PL327456A1 (en)	1998-12-07
ATE232906T1 (de)	2003-03-15
DE69626308T2 (de)	2003-07-24
BR9612082A (pt)	1999-05-11
AU716642B2 (en)	2000-03-02
NO982880D0 (no)	1998-06-19
CA2240408C (en)	2007-04-24
SK86498A3 (en)	1999-01-11
JP2008259512A (ja)	2008-10-30
HK1010563A1 (en)	1999-06-25
HUP9902113A2 (hu)	1999-11-29
PL185775B1 (pl)	2003-07-31
MX9804958A (es)	1998-09-30
CZ191698A3 (cs)	1998-10-14
KR100456181B1 (ko)	2004-12-31
ES2187684T3 (es)	2003-06-16
JP2007020573A (ja)	2007-02-01
KR20000064470A (ko)	2000-11-06
IL125005A0 (en)	1999-01-26
HU225765B1 (en)	2007-08-28
JP4906785B2 (ja)	2012-03-28
DE69626308D1 (de)	2003-03-27
EP0868525B1 (de)	2003-02-19
WO1997022710A1 (en)	1997-06-26
CZ292649B6 (cs)	2003-11-12
NO320154B1 (no)	2005-11-07
NZ325566A (en)	1999-05-28
EP0868525A1 (de)	1998-10-07
NO982880L (no)	1998-06-19
AU1410197A (en)	1997-07-20
HUP9902113A3 (en)	2001-02-28
JP2011139715A (ja)	2011-07-21
IL125005A (en)	2006-04-10
CN1090240C (zh)	2002-09-04

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