DK0889736T3 - Iscom eller iscom-matrix, der omfatter et stof, der retter sig mod mucus, og et antigen - Google Patents
Iscom eller iscom-matrix, der omfatter et stof, der retter sig mod mucus, og et antigenInfo
- Publication number
- DK0889736T3 DK0889736T3 DK97905541T DK97905541T DK0889736T3 DK 0889736 T3 DK0889736 T3 DK 0889736T3 DK 97905541 T DK97905541 T DK 97905541T DK 97905541 T DK97905541 T DK 97905541T DK 0889736 T3 DK0889736 T3 DK 0889736T3
- Authority
- DK
- Denmark
- Prior art keywords
- iscom
- mucus
- antigen
- matrix
- substance targeting
- Prior art date
Links
- 230000008685 targeting Effects 0.000 title abstract 2
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 239000011159 matrix material Substances 0.000 title 1
- 210000003097 mucus Anatomy 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 230000002163 immunogen Effects 0.000 abstract 2
- 210000004400 mucous membrane Anatomy 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 210000003563 lymphoid tissue Anatomy 0.000 abstract 1
- 230000010415 tropism Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9600647A SE9600647D0 (sv) | 1996-02-21 | 1996-02-21 | Ny användning |
| PCT/SE1997/000289 WO1997030728A1 (en) | 1996-02-21 | 1997-02-20 | Iscom or iscom-matrix comprising a mucus targetting substance and optionally, an antigen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0889736T3 true DK0889736T3 (da) | 2004-04-19 |
Family
ID=20401481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97905541T DK0889736T3 (da) | 1996-02-21 | 1997-02-20 | Iscom eller iscom-matrix, der omfatter et stof, der retter sig mod mucus, og et antigen |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6607732B2 (da) |
| EP (1) | EP0889736B1 (da) |
| JP (1) | JP2000504746A (da) |
| AT (1) | ATE255905T1 (da) |
| AU (1) | AU719084B2 (da) |
| CA (1) | CA2247522C (da) |
| DE (1) | DE69726712T2 (da) |
| DK (1) | DK0889736T3 (da) |
| ES (1) | ES2210495T3 (da) |
| NZ (1) | NZ331403A (da) |
| SE (1) | SE9600647D0 (da) |
| WO (1) | WO1997030728A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
| US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
| DK1077722T3 (da) | 1998-05-22 | 2006-11-27 | Ottawa Health Research Inst | Fremgangsmåder og produkter til induktion af mukosaimmunitet |
| US7041296B1 (en) * | 1999-11-12 | 2006-05-09 | The United States Of America As Represented By The Department Of Health And Human Services | Methods of treating inflammatory bowel disease using cholera toxin B subunit |
| US7713942B2 (en) * | 2001-04-04 | 2010-05-11 | Nordic Vaccine Technology A/S | Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides |
| SE0202110D0 (sv) | 2002-07-05 | 2002-07-05 | Isconova Ab | Iscom preparation and use thereof |
| SE0301998D0 (sv) | 2003-07-07 | 2003-07-07 | Isconova Ab | Quil A fraction with low toxicity and use thereof |
| ES2433467T3 (es) | 2005-01-20 | 2013-12-11 | Isconova Ab | Composición de vacuna que comprende una proteína de unión a fibronectina o un péptido de unión a fibronectina |
| CA2698392C (en) | 2007-09-04 | 2019-12-03 | Baoming Jiang | Thermal inactivation of rotavirus |
| GB0803076D0 (en) | 2008-02-20 | 2008-03-26 | Univ Ghent | Mucosal Membrane Receptor and uses thereof |
| ES2325243B1 (es) * | 2008-02-27 | 2011-05-04 | Universidad De Granada | Antigeno recombinante. |
| ES2987238T3 (es) | 2008-12-09 | 2024-11-14 | Novavax Inc | Proteínas F del RSV modificadas y métodos de su uso |
| CA2805741C (en) | 2010-07-23 | 2019-08-13 | Karin Bengtsson Loevgren | Composition including an iscom matrix and ectodomains |
| ES2639122T3 (es) | 2011-05-13 | 2017-10-25 | Zoetis Services Llc | Composiciones inmunogénicas de glucoproteína G de virus Hendra y Nipah |
| DK2750683T4 (da) | 2011-10-03 | 2021-04-12 | Croda Int Plc | Nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf som bærer for amfipatiske eller hydrofobe molekyler inden for medicin, herunder cancerbehandling, og i fødevarerelaterede forbindelser |
| EP4272750A3 (en) | 2013-02-07 | 2024-01-24 | Children's Medical Center, Corp. | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| WO2014163558A1 (en) | 2013-04-01 | 2014-10-09 | Moreinx Ab | Nanoparticles, composed of sterol and saponin from quillaja saponaria molina process for preparation and use thereof as carrier for amphipatic of hydrphobic molecules in fields of medicine including cancer treatment and food related compounds |
| EP3082856A1 (en) | 2013-12-16 | 2016-10-26 | Zoetis Services LLC | Hendra and nipah virus g glycoprotein immunogenic compositions |
| CN114617959A (zh) | 2015-09-03 | 2022-06-14 | 诺瓦瓦克斯股份有限公司 | 具有改进的稳定性和免疫原性的疫苗组合物 |
| CN111148509A (zh) | 2017-07-24 | 2020-05-12 | 诺瓦瓦克斯股份有限公司 | 治疗呼吸系统疾病的方法和组合物 |
| CN120227451A (zh) | 2018-03-19 | 2025-07-01 | 诺瓦瓦克斯股份有限公司 | 多价流感纳米颗粒疫苗 |
| AU2021214064A1 (en) | 2020-01-27 | 2022-08-18 | Novavax, Inc. | Coronavirus vaccine formulations |
| US10953089B1 (en) | 2020-01-27 | 2021-03-23 | Novavax, Inc. | Coronavirus vaccine formulations |
| JP2024516309A (ja) | 2021-05-05 | 2024-04-12 | ノババックス，インコーポレイテッド | コロナウイルス組成物及びインフルエンザ組成物ならびにそれらの使用方法 |
| GB202209588D0 (en) | 2022-06-29 | 2022-08-10 | Plant Bioscience Ltd | Methods and compositions |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6290962B1 (en) * | 1992-11-03 | 2001-09-18 | Oravax, Inc. | Urease-based vaccine and treatment for helicobacter infection |
-
1996
- 1996-02-21 SE SE9600647A patent/SE9600647D0/xx unknown
-
1997
- 1997-02-20 JP JP9530070A patent/JP2000504746A/ja active Pending
- 1997-02-20 AT AT97905541T patent/ATE255905T1/de not_active IP Right Cessation
- 1997-02-20 AU AU22385/97A patent/AU719084B2/en not_active Expired
- 1997-02-20 CA CA002247522A patent/CA2247522C/en not_active Expired - Lifetime
- 1997-02-20 EP EP97905541A patent/EP0889736B1/en not_active Expired - Lifetime
- 1997-02-20 ES ES97905541T patent/ES2210495T3/es not_active Expired - Lifetime
- 1997-02-20 NZ NZ331403A patent/NZ331403A/en not_active IP Right Cessation
- 1997-02-20 DK DK97905541T patent/DK0889736T3/da active
- 1997-02-20 DE DE69726712T patent/DE69726712T2/de not_active Expired - Lifetime
- 1997-02-20 WO PCT/SE1997/000289 patent/WO1997030728A1/en not_active Ceased
-
1998
- 1998-08-20 US US09/137,236 patent/US6607732B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000504746A (ja) | 2000-04-18 |
| EP0889736B1 (en) | 2003-12-10 |
| US20020131982A1 (en) | 2002-09-19 |
| CA2247522C (en) | 2009-12-29 |
| ATE255905T1 (de) | 2003-12-15 |
| DE69726712T2 (de) | 2004-10-07 |
| AU2238597A (en) | 1997-09-10 |
| WO1997030728A1 (en) | 1997-08-28 |
| CA2247522A1 (en) | 1997-08-28 |
| NZ331403A (en) | 2000-02-28 |
| DE69726712D1 (de) | 2004-01-22 |
| EP0889736A1 (en) | 1999-01-13 |
| US6607732B2 (en) | 2003-08-19 |
| AU719084B2 (en) | 2000-05-04 |
| SE9600647D0 (sv) | 1996-02-21 |
| ES2210495T3 (es) | 2004-07-01 |
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