DK0891223T3 - Fremgangsmåder til fremstilling af harpikser med ligander fæstnet dertil gennem en bindingsgruppe, der omfatter sulfid-, sulfoxid- eller sulfonfunktionalitet - Google Patents
Fremgangsmåder til fremstilling af harpikser med ligander fæstnet dertil gennem en bindingsgruppe, der omfatter sulfid-, sulfoxid- eller sulfonfunktionalitetInfo
- Publication number
- DK0891223T3 DK0891223T3 DK97901278T DK97901278T DK0891223T3 DK 0891223 T3 DK0891223 T3 DK 0891223T3 DK 97901278 T DK97901278 T DK 97901278T DK 97901278 T DK97901278 T DK 97901278T DK 0891223 T3 DK0891223 T3 DK 0891223T3
- Authority
- DK
- Denmark
- Prior art keywords
- sulfide
- sulfoxide
- methods
- functionality
- linking group
- Prior art date
Links
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 150000003457 sulfones Chemical group 0.000 title abstract 3
- 150000003462 sulfoxides Chemical class 0.000 title abstract 3
- 239000003446 ligand Substances 0.000 title abstract 2
- 125000005647 linker group Chemical group 0.000 title abstract 2
- 229920005989 resin Polymers 0.000 title abstract 2
- 239000011347 resin Substances 0.000 title abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 2
- LSNNMFCWUKXFEE-UHFFFAOYSA-N Sulfurous acid Chemical class OS(O)=O LSNNMFCWUKXFEE-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000007348 radical reaction Methods 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 abstract 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/06—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group B01J20/04
- B01J20/08—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group B01J20/04 comprising aluminium oxide or hydroxide; comprising bauxite
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
- B01J20/103—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate comprising silica
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
- B01J20/10—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising silica or silicate
- B01J20/16—Alumino-silicates
- B01J20/165—Natural alumino-silicates, e.g. zeolites
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
- B01J20/289—Phases chemically bonded to a substrate, e.g. to silica or to polymers bonded via a spacer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3204—Inorganic carriers, supports or substrates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
- B01J20/3206—Organic carriers, supports or substrates
- B01J20/3208—Polymeric carriers, supports or substrates
- B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3214—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the method for obtaining this coating or impregnating
- B01J20/3217—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond
- B01J20/3219—Resulting in a chemical bond between the coating or impregnating layer and the carrier, support or substrate, e.g. a covalent bond involving a particular spacer or linking group, e.g. for attaching an active group
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
- B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
- B01J20/3255—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising a cyclic structure containing at least one of the heteroatoms nitrogen, oxygen or sulfur, e.g. heterocyclic or heteroaromatic structures
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2220/00—Aspects relating to sorbent materials
- B01J2220/50—Aspects relating to the use of sorbent or filter aid materials
- B01J2220/54—Sorbents specially adapted for analytical or investigative chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polyesters Or Polycarbonates (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Graft Or Block Polymers (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/584,423 US5789578A (en) | 1996-01-11 | 1996-01-11 | Methods for the preparation of resins with ligands attached thereto through a linking group comprising sulfide, sulfoxide or sulfone functionality |
| EP97901278A EP0891223B1 (de) | 1996-01-11 | 1997-01-10 | Methode zur herstellung von harzen mit daran befestigten liganden, wobei die verbindende funktionelle gruppe sulfid, sulfoxid oder sulfon umfasst |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0891223T3 true DK0891223T3 (da) | 2005-02-14 |
Family
ID=24337265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97901278T DK0891223T3 (da) | 1996-01-11 | 1997-01-10 | Fremgangsmåder til fremstilling af harpikser med ligander fæstnet dertil gennem en bindingsgruppe, der omfatter sulfid-, sulfoxid- eller sulfonfunktionalitet |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5789578A (de) |
| EP (2) | EP0891223B1 (de) |
| JP (1) | JP3970928B2 (de) |
| AT (1) | ATE279977T1 (de) |
| AU (1) | AU722740B2 (de) |
| CA (1) | CA2240064C (de) |
| DE (1) | DE69731287T2 (de) |
| DK (1) | DK0891223T3 (de) |
| ES (1) | ES2227666T3 (de) |
| NZ (1) | NZ326487A (de) |
| PT (1) | PT891223E (de) |
| WO (1) | WO1997025139A1 (de) |
Families Citing this family (39)
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| SE0003358D0 (sv) * | 2000-09-19 | 2000-09-19 | Amersham Pharm Biotech Ab | Charged carrier material and its use |
| SE0004808D0 (sv) * | 2000-12-20 | 2000-12-20 | Apbiotech Ab | Method for the purification of an enzyme |
| GB2377447B (en) * | 2001-04-18 | 2003-06-25 | Amersham Biosciences Ab | Isolation of dna molecules |
| SE0103084D0 (sv) * | 2001-09-14 | 2001-09-14 | Amersham Pharm Biotech Ab | Generation of ion exchange media |
| US7144743B2 (en) * | 2002-09-13 | 2006-12-05 | Pall Corporation | Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays |
| JP4801598B2 (ja) * | 2004-01-20 | 2011-10-26 | ポール・コーポレーション | 生理的イオン強度でタンパク質を吸着させるためのクロマトグラフィー材料 |
| SE529259C2 (sv) * | 2005-08-31 | 2007-06-12 | Ge Healthcare Bio Sciences Ab | Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi |
| WO2007058599A1 (en) * | 2005-11-21 | 2007-05-24 | Ge Healthcare Bio-Sciences Ab | Manufacture of a chromatography matrix |
| US8431748B2 (en) * | 2006-01-16 | 2013-04-30 | Bwe I Malmo Ab | Low protonation constant hydroxy acids |
| EP2043767B1 (de) | 2006-07-14 | 2020-03-25 | Wisconsin Alumni Research Foundation | Adsorptionsmembranen zum einfangen von viren |
| JP5999899B2 (ja) | 2008-04-08 | 2016-09-28 | バイオ−ラッド ラボラトリーズ インコーポレーティッド | 抗体のクロマトグラフィー精製法 |
| US20100196272A1 (en) | 2009-01-30 | 2010-08-05 | Neoprobe Corporation | Compositions for radiolabeling diethylenetriaminepentaacetic acid (dtpa)-dextran |
| US8962823B2 (en) | 2010-01-19 | 2015-02-24 | Organoclick Ab | Heterogeneous thiol-ene click modifications of solid polysaccharide-based materials |
| JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
| US8802448B2 (en) * | 2011-07-27 | 2014-08-12 | Pall Corporation | Mixed mode ligands |
| CN104160048B (zh) * | 2011-10-07 | 2017-06-06 | 东曹株式会社 | 钯分离剂、以及其制造方法和用途 |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| WO2013151663A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of membrane proteins |
| EP2983804A4 (de) | 2013-03-15 | 2017-03-01 | Moderna Therapeutics, Inc. | Ionenaustauschreinigung von mrna |
| US10077439B2 (en) | 2013-03-15 | 2018-09-18 | Modernatx, Inc. | Removal of DNA fragments in mRNA production process |
| EP2971161B1 (de) | 2013-03-15 | 2018-12-26 | ModernaTX, Inc. | Nukleinsäurereinigung |
| EP2971033B8 (de) | 2013-03-15 | 2019-07-10 | ModernaTX, Inc. | Herstellungsverfahren zur herstellung von rna-transkripten |
| HUE056760T2 (hu) | 2013-07-11 | 2022-03-28 | Modernatx Inc | A CRISPR-hez kapcsolódó fehérjéket és a szintetikus SGRNS-ket kódoló szintetikus polinukleotidokat tartalmazó készítmények és felhasználási módjaik |
| WO2015051169A2 (en) | 2013-10-02 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotide molecules and uses thereof |
| JP5825612B2 (ja) * | 2013-11-14 | 2015-12-02 | 学校法人兵庫医科大学 | 新規固相担体 |
| WO2015196128A2 (en) | 2014-06-19 | 2015-12-23 | Moderna Therapeutics, Inc. | Alternative nucleic acid molecules and uses thereof |
| CA2955238A1 (en) | 2014-07-16 | 2016-01-21 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| JP6602533B2 (ja) * | 2014-09-02 | 2019-11-06 | Jsr株式会社 | 担体の製造方法、担体、クロマトグラフィーカラム、及び目的物質の精製方法 |
| WO2017049286A1 (en) | 2015-09-17 | 2017-03-23 | Moderna Therapeutics, Inc. | Polynucleotides containing a morpholino linker |
| SI3350333T1 (sl) | 2015-09-17 | 2022-04-29 | ModernaTX,Inc. | Polinukleotidi, ki zajemajo stabilizacijsko repno regijo |
| US12385034B2 (en) | 2016-06-24 | 2025-08-12 | Modernatx, Inc. | Methods and apparatus for filtration |
| US10315185B2 (en) * | 2016-07-14 | 2019-06-11 | University Of Oregon | Polyfunctional sorbent materials |
| CN110144019B (zh) * | 2018-02-10 | 2021-03-23 | 合肥博思科创医药科技有限公司 | 一种舒更葡糖钠粗品的精制纯化方法 |
| JP2024024315A (ja) * | 2022-08-09 | 2024-02-22 | 学校法人同志社 | 新規化合物及びその製造方法 |
| CN118106042A (zh) * | 2024-03-25 | 2024-05-31 | 浙江大学衢州研究院 | 一种磺酸基阳离子交换介质的制备方法 |
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| IL89047A0 (en) * | 1989-01-24 | 1989-08-15 | Yeda Res & Dev | Thiophilic adsorbents |
| GB8902761D0 (en) * | 1989-02-08 | 1989-03-30 | Ici Plc | Cation echange membranes |
| JPH0778081B2 (ja) * | 1990-07-19 | 1995-08-23 | 静岡大学長 | 機能化高分子の合成方法 |
| SE468814B (sv) * | 1991-07-22 | 1993-03-22 | Inovata Ab | Foerfarande foer att binda en foerening innehaallande en nukleofil grupp till en amin -och/eller hydroxigrupphaltig polymer |
| DE9300912U1 (de) * | 1993-01-23 | 1993-04-29 | Macherey, Nagel GmbH & Co. Handelsgesellschaft, 52355 Düren | Trennmaterial für die Chromatographie |
| US5502022A (en) * | 1994-05-16 | 1996-03-26 | Biosepra, Inc. | Chromatography adsorbents utilizing mercapto heterocyclic ligands |
| US20040214157A1 (en) * | 1994-06-29 | 2004-10-28 | Simon C. Burton | Chromatographic resins and methods for using same |
-
1996
- 1996-01-11 US US08/584,423 patent/US5789578A/en not_active Expired - Lifetime
-
1997
- 1997-01-10 JP JP52511097A patent/JP3970928B2/ja not_active Expired - Lifetime
- 1997-01-10 EP EP97901278A patent/EP0891223B1/de not_active Expired - Lifetime
- 1997-01-10 PT PT97901278T patent/PT891223E/pt unknown
- 1997-01-10 NZ NZ326487A patent/NZ326487A/xx not_active IP Right Cessation
- 1997-01-10 AT AT97901278T patent/ATE279977T1/de active
- 1997-01-10 CA CA002240064A patent/CA2240064C/en not_active Expired - Lifetime
- 1997-01-10 AU AU14577/97A patent/AU722740B2/en not_active Expired
- 1997-01-10 WO PCT/NZ1997/000002 patent/WO1997025139A1/en not_active Ceased
- 1997-01-10 ES ES97901278T patent/ES2227666T3/es not_active Expired - Lifetime
- 1997-01-10 DE DE69731287T patent/DE69731287T2/de not_active Expired - Lifetime
- 1997-01-10 DK DK97901278T patent/DK0891223T3/da active
- 1997-01-10 EP EP04015823A patent/EP1464391A3/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ATE279977T1 (de) | 2004-11-15 |
| EP1464391A3 (de) | 2004-12-29 |
| CA2240064C (en) | 2005-08-02 |
| JP3970928B2 (ja) | 2007-09-05 |
| EP0891223B1 (de) | 2004-10-20 |
| NZ326487A (en) | 1999-11-29 |
| EP0891223A1 (de) | 1999-01-20 |
| CA2240064A1 (en) | 1997-07-17 |
| JP2000502951A (ja) | 2000-03-14 |
| AU1457797A (en) | 1997-08-01 |
| EP0891223A4 (de) | 1999-07-28 |
| WO1997025139A1 (en) | 1997-07-17 |
| DE69731287T2 (de) | 2005-10-13 |
| ES2227666T3 (es) | 2005-04-01 |
| US5789578A (en) | 1998-08-04 |
| DE69731287D1 (de) | 2004-11-25 |
| AU722740B2 (en) | 2000-08-10 |
| EP1464391A2 (de) | 2004-10-06 |
| PT891223E (pt) | 2005-02-28 |
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