DK0897914T3 - Fremgangsmåde til fremstilling af 2,5-disubstituerede pyridiner - Google Patents
Fremgangsmåde til fremstilling af 2,5-disubstituerede pyridinerInfo
- Publication number
- DK0897914T3 DK0897914T3 DK98114969T DK98114969T DK0897914T3 DK 0897914 T3 DK0897914 T3 DK 0897914T3 DK 98114969 T DK98114969 T DK 98114969T DK 98114969 T DK98114969 T DK 98114969T DK 0897914 T3 DK0897914 T3 DK 0897914T3
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compound
- chem
- signifies
- preparation
- Prior art date
Links
- -1 2,5-Disubstituted Pyridines Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000012433 hydrogen halide Substances 0.000 abstract 1
- 229910000039 hydrogen halide Inorganic materials 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/08—Preparation by ring-closure
- C07D213/09—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles
- C07D213/10—Preparation by ring-closure involving the use of ammonia, amines, amine salts, or nitriles from acetaldehyde or cyclic polymers thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97114269 | 1997-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0897914T3 true DK0897914T3 (da) | 2004-09-27 |
Family
ID=8227241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98114969T DK0897914T3 (da) | 1997-08-19 | 1998-08-10 | Fremgangsmåde til fremstilling af 2,5-disubstituerede pyridiner |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6080866A (da) |
| EP (1) | EP0897914B1 (da) |
| JP (1) | JP3025239B2 (da) |
| KR (1) | KR100275663B1 (da) |
| CN (1) | CN1103335C (da) |
| AT (1) | ATE267808T1 (da) |
| CA (1) | CA2245169C (da) |
| DE (1) | DE69824090T2 (da) |
| DK (1) | DK0897914T3 (da) |
| ES (1) | ES2221696T3 (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6743783B1 (en) * | 1993-12-01 | 2004-06-01 | Marine Polymer Technologies, Inc. | Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine |
| US6417360B1 (en) | 1999-03-03 | 2002-07-09 | Hoffmann-La Roche Inc. | Heterocyclic sulfonamides |
| ZA200002318B (en) * | 1999-05-22 | 2000-11-16 | Actelion Pharmaceuticals Ltd | Aqueous pharmaceutical composition. |
| ES2918452T3 (es) * | 2007-02-19 | 2022-07-15 | Marine Polymer Tech Inc | Composiciones hemostáticas y regímenes terapéuticos |
| NZ703163A (en) | 2010-04-15 | 2016-06-24 | Marinepolymer Tech Inc | Anti-bacterial applications of poly-n-acetylglucosamine nanofibers |
| EP2696680B1 (en) | 2011-04-15 | 2018-11-28 | Marine Polymer Technologies, Inc. | Treatment of hsv infections with poly-n-acetyl glucosamine nanofibers |
| CA3197265A1 (en) | 2020-11-05 | 2022-05-12 | Timo Rager | A stable crystalline hydrate of clazosentan disodium salt |
| EP4582086A3 (en) | 2021-12-17 | 2025-07-23 | Idorsia Pharmaceuticals Ltd | Clazosentan disodium salt, its preparation and pharmaceutical compositions comprising the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU571683B2 (en) * | 1984-05-23 | 1988-04-21 | Zeneca Ag Products Inc. | 2-substituted-5-methylpyridines from methylcyclobutane- carbonitrile, valeronitrile and pentenonitrile intermediates |
| DE4223013A1 (de) * | 1992-07-13 | 1994-01-20 | Bayer Ag | Verfahren zur Herstellung von 2,5-disubstituierten Pyridinen |
| CA2162630C (en) * | 1994-11-25 | 2007-05-01 | Volker Breu | Sulfonamides |
| US5837708A (en) * | 1994-11-25 | 1998-11-17 | Hoffmann-La Roche Inc. | Sulphonamides |
| TW313568B (da) * | 1994-12-20 | 1997-08-21 | Hoffmann La Roche |
-
1998
- 1998-08-10 DK DK98114969T patent/DK0897914T3/da active
- 1998-08-10 ES ES98114969T patent/ES2221696T3/es not_active Expired - Lifetime
- 1998-08-10 AT AT98114969T patent/ATE267808T1/de active
- 1998-08-10 EP EP98114969A patent/EP0897914B1/en not_active Expired - Lifetime
- 1998-08-10 DE DE69824090T patent/DE69824090T2/de not_active Expired - Lifetime
- 1998-08-17 CN CN98118370A patent/CN1103335C/zh not_active Expired - Lifetime
- 1998-08-18 JP JP10231239A patent/JP3025239B2/ja not_active Expired - Lifetime
- 1998-08-18 CA CA002245169A patent/CA2245169C/en not_active Expired - Lifetime
- 1998-08-18 US US09/136,118 patent/US6080866A/en not_active Expired - Lifetime
- 1998-08-18 KR KR1019980033472A patent/KR100275663B1/ko not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6080866A (en) | 2000-06-27 |
| ES2221696T3 (es) | 2005-01-01 |
| CA2245169C (en) | 2004-08-10 |
| JP3025239B2 (ja) | 2000-03-27 |
| JPH11116554A (ja) | 1999-04-27 |
| CN1210105A (zh) | 1999-03-10 |
| CA2245169A1 (en) | 1999-02-19 |
| ATE267808T1 (de) | 2004-06-15 |
| KR19990023680A (ko) | 1999-03-25 |
| DE69824090D1 (de) | 2004-07-01 |
| CN1103335C (zh) | 2003-03-19 |
| KR100275663B1 (ko) | 2000-12-15 |
| EP0897914B1 (en) | 2004-05-26 |
| EP0897914A1 (en) | 1999-02-24 |
| DE69824090T2 (de) | 2005-07-07 |
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