DK0900569T3 - Terapeutisk middel til behandling af herniaramt intervertebral diskus - Google Patents

Terapeutisk middel til behandling af herniaramt intervertebral diskus

Info

Publication number
DK0900569T3
DK0900569T3 DK98306691T DK98306691T DK0900569T3 DK 0900569 T3 DK0900569 T3 DK 0900569T3 DK 98306691 T DK98306691 T DK 98306691T DK 98306691 T DK98306691 T DK 98306691T DK 0900569 T3 DK0900569 T3 DK 0900569T3
Authority
DK
Denmark
Prior art keywords
treatment
intervertebral disc
herniaric
therapeutic agent
epidurally
Prior art date
Application number
DK98306691T
Other languages
Danish (da)
English (en)
Inventor
Yutaka Nohara
Hiroki Ishikawa
Original Assignee
Seikagaku Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Kogyo Co Ltd filed Critical Seikagaku Kogyo Co Ltd
Application granted granted Critical
Publication of DK0900569T3 publication Critical patent/DK0900569T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK98306691T 1997-08-22 1998-08-20 Terapeutisk middel til behandling af herniaramt intervertebral diskus DK0900569T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22687297 1997-08-22

Publications (1)

Publication Number Publication Date
DK0900569T3 true DK0900569T3 (da) 2003-01-27

Family

ID=16851905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98306691T DK0900569T3 (da) 1997-08-22 1998-08-20 Terapeutisk middel til behandling af herniaramt intervertebral diskus

Country Status (9)

Country Link
US (1) US6063378A (de)
EP (1) EP0900569B1 (de)
AT (1) ATE225184T1 (de)
AU (1) AU735216B2 (de)
CA (1) CA2246033C (de)
DE (1) DE69808402T2 (de)
DK (1) DK0900569T3 (de)
ES (1) ES2185117T3 (de)
RU (1) RU2209080C2 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU772479B2 (en) * 1998-10-06 2004-04-29 Stryker Corporation Repair of larynx, trachea, and other fibrocartilaginous tissues
US6783546B2 (en) 1999-09-13 2004-08-31 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US6371984B1 (en) * 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US7052516B2 (en) 1999-10-20 2006-05-30 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and deformable spinal disc annulus stent
US8128698B2 (en) 1999-10-20 2012-03-06 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8632590B2 (en) 1999-10-20 2014-01-21 Anulex Technologies, Inc. Apparatus and methods for the treatment of the intervertebral disc
US7004970B2 (en) 1999-10-20 2006-02-28 Anulex Technologies, Inc. Methods and devices for spinal disc annulus reconstruction and repair
US7615076B2 (en) 1999-10-20 2009-11-10 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6592625B2 (en) 1999-10-20 2003-07-15 Anulex Technologies, Inc. Spinal disc annulus reconstruction method and spinal disc annulus stent
US7935147B2 (en) 1999-10-20 2011-05-03 Anulex Technologies, Inc. Method and apparatus for enhanced delivery of treatment device to the intervertebral disc annulus
US6805695B2 (en) 2000-04-04 2004-10-19 Spinalabs, Llc Devices and methods for annular repair of intervertebral discs
US20030069639A1 (en) * 2001-04-14 2003-04-10 Tom Sander Methods and compositions for repair or replacement of joints and soft tissues
JP4125234B2 (ja) 2001-11-01 2008-07-30 スパイン・ウェイブ・インコーポレーテッド 椎間板間の終板の前処理のための装置及び方法
JP3993855B2 (ja) * 2001-11-01 2007-10-17 スパイン・ウェイブ・インコーポレーテッド 脊椎椎間板の回復のための装置
US8183350B2 (en) * 2002-05-04 2012-05-22 Acorda Therapeutics, Inc. Compositions and methods for promoting neuronal outgrowth
CA2493509C (en) * 2002-06-03 2010-03-09 Massachusetts Institute Of Technology Rationally designed polysaccharide lyases derived from chondroitinase b
US7163545B2 (en) * 2002-07-29 2007-01-16 Mayo Foundation For Medical Education And Research Spinal cord surgical implant
AU2003265561A1 (en) * 2002-08-15 2004-03-03 Acorda Therapeutics, Inc. Chimeric protein
EP1616955A4 (de) * 2003-03-31 2006-08-30 Seikagaku Kogyo Co Ltd Katalysator für die spaltung von zuckerketten
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
EP3211084B1 (de) 2003-05-16 2019-03-27 Acorda Therapeutics, Inc. Proteoglycan-abbauende mutanten zur behandlung des zns
EP1631234B1 (de) * 2003-05-16 2011-09-14 Acorda Therapeutics, Inc. Zusammensetzungen und verfahren zur behandlung von zns-schäden
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
JP4440939B2 (ja) 2004-01-08 2010-03-24 スパイン・ウェイブ・インコーポレーテッド 伸延した組織部位に流動性材料を注入する装置及び方法
MXPA06013345A (es) * 2004-05-18 2008-10-31 Acorda Therapeutics Inc Metodos para purificar condrointinasa y sus formulaciones estables.
US7837733B2 (en) * 2004-06-29 2010-11-23 Spine Wave, Inc. Percutaneous methods for injecting a curable biomaterial into an intervertebral space
US9968120B2 (en) * 2006-05-17 2018-05-15 Dsm Nutritional Products Ag Homogenized formulations containing microcapsules and methods of making and using thereof
JP5189985B2 (ja) 2005-09-26 2013-04-24 アコーダ セラピューティクス、インク． コンドロイチナーゼａｂｃｉ変異体を用いた組成物およびその使用方法
US8642059B2 (en) 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
CA3009034C (en) 2006-10-10 2020-08-18 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
US8163022B2 (en) 2008-10-14 2012-04-24 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US8652153B2 (en) 2010-01-11 2014-02-18 Anulex Technologies, Inc. Intervertebral disc annulus repair system and bone anchor delivery tool
LT2588130T (lt) 2010-06-25 2016-12-12 Shire Human Genetic Therapies, Inc. Terapinės priemonės pristatymas cns
KR20230159646A (ko) * 2010-06-25 2023-11-21 샤이어 휴먼 지네틱 테라피즈 인크. 이듀로네이트-2-설파타제의 cns 전달을 위한 방법들 및 조성물들
HRP20191923T1 (hr) 2010-06-25 2020-01-10 Shire Human Genetic Therapies, Inc. Postupci i sastavi za isporuku arilsulfataze a u cns
JP6073783B2 (ja) 2010-06-25 2017-02-01 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド ヘパランｎ−スルファターゼのｃｎｓ送達のための方法および組成物
PT3103469T (pt) 2010-06-25 2021-03-04 Shire Human Genetic Therapies Administração de agentes terapêuticos no snc
WO2012081227A1 (ja) * 2010-12-13 2012-06-21 生化学工業株式会社 椎間板ヘルニア治療剤
US20140377244A1 (en) 2011-12-23 2014-12-25 Shire Human Genetic Therapies, Inc. Stable formulations for cns delivery of arylsulfatase a
US9737294B2 (en) 2013-01-28 2017-08-22 Cartiva, Inc. Method and system for orthopedic repair
WO2014117107A1 (en) 2013-01-28 2014-07-31 Cartiva, Inc. Systems and methods for orthopedic repair
AU2015233396B2 (en) * 2014-03-20 2020-01-30 Stayble Therapeutics Ab A composition for use in the treatment of intervertebral disc-related pain

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696816A (en) * 1985-11-07 1987-09-29 Brown Mark D Method for treating intervertebral disc displacement with enzymes
RU2021812C1 (ru) * 1992-04-13 1994-10-30 Всесоюзный научно-исследовательский институт технологии кровезаменителей и гормональных препаратов Средство для лечения артрологических заболеваний
US5496718A (en) * 1992-06-26 1996-03-05 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Chondroitinase ABC isolated from proteus vulgaris ATCC 6896
JP3419811B2 (ja) * 1993-02-24 2003-06-23 マルハ株式会社 コンドロイチナーゼ遺伝子
US6228998B1 (en) * 1994-07-22 2001-05-08 Seikagaku Kogyo Kabushiki Kaisha Amino spacered glycosaminoglycan derivatives and their use in copolymerization with acrylamide
DE69829605T2 (de) * 1997-05-02 2006-02-09 Seikagaku Corp. Chondroitinase enthaltende Zusammensetzungen

Also Published As

Publication number Publication date
ATE225184T1 (de) 2002-10-15
ES2185117T3 (es) 2003-04-16
EP0900569A3 (de) 1999-04-07
EP0900569A2 (de) 1999-03-10
AU8082698A (en) 1999-03-04
CA2246033C (en) 2012-12-04
AU735216B2 (en) 2001-07-05
DE69808402T2 (de) 2003-07-03
US6063378A (en) 2000-05-16
DE69808402D1 (de) 2002-11-07
CA2246033A1 (en) 1999-02-22
EP0900569B1 (de) 2002-10-02
RU2209080C2 (ru) 2003-07-27

Similar Documents

Publication Publication Date Title
DK0900569T3 (da) Terapeutisk middel til behandling af herniaramt intervertebral diskus
DK1229873T3 (da) Forbinding af hydrogeler til nucleus pulposussubstitution i intervertebralskiver
RU98116128A (ru) Фармацевтическая композиция, включающая фермент, разрушающий гликозаменогликаны, и применение указанного фермента для получения лекарственного препарата для терапии грыжи межпозвоночного диска
DK162472C (da) Laegemiddelform til afgivelse af et terapeutisk middel i periodontallommen og dens omgivelser
IT1209663B (it) Derivati eterociclici aromatici eloro applicazione nei settori terapeutico e cosmetico.
FR2707480B1 (fr) Prothèse discale intervertébrale.
GB2358589B (en) Valve structure
DE69734395D1 (de) Verbesserte chondrogene differenzierung von menschlichen mesenchym-stammzellen
NO328898B1 (no) Stabile, flytende farmasoytiske formuleringer av botulinumtoksin, samt anvendelse derav.
BR0214650A (pt) Imunocitoquinas com seletividade modulada
TR26927A (tr) Intervetrebral disk protezi.
FR2709949B1 (fr) Prothèse de disque intervertébral.
DZ2494A1 (fr) Composition pharmaceutique d'oméprazole.
DK0698109T3 (da) Genoverføring til pancreasepithelceller
ATE273031T1 (de) Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen
ATE226947T1 (de) 2-substituierte 1,2,5-thiadiazolidin-3-on-1,1- dioxiden, zusammensetzung und deren verwendung
ES2173887T3 (es) Nuevos usos farmaceuticos de las enzimas de krill.
DE59400102D1 (de) Bandscheibenteilersatz
DK0706385T3 (da) Anvendelse af isovaleramid som et mildt anxiolytisk og et mildt sedativt middel
DE69705590D1 (de) Fluorierte polyfunktionelle (meth)acrylester, fluormonomer-zusammensetzung, material mit niedrigem brechungsindex und niedrig-reflektierender film
DE3765885D1 (de) Optisch-aktive 2-methyl-1,3-propandiol-derivate, sie enthaltende fluessigkristalline zusammensetzungen und optisches schaltendes element.
DE69333341T2 (de) Heterologe Genexpression in Bacillus Subtilis: der Fusionsansatz
DE69101219D1 (de) Lipase enthaltendes flüssiges einweichmittel und dessen verwendung.
BR9709406B1 (pt) fluorenonas alquiloxiamino substituìdas e composição farmacêutica contendo as mesmas.
DE3873016D1 (de) Optisch aktive, delta-valerolacton-ring enthaltende verbindung und dieselbe enthaltende fluessigkristalline zusammensetzung.