DK0907363T3 - Lægemiddel, der omfatter (-)-8-[(4-amino-1-methylbutyl)amino]-5-(3,4-dichlorphenoxy)-6-methoxy-4-methylquinolin, til behandling af parasitiske og opportunistiske infektioner - Google Patents

Lægemiddel, der omfatter (-)-8-[(4-amino-1-methylbutyl)amino]-5-(3,4-dichlorphenoxy)-6-methoxy-4-methylquinolin, til behandling af parasitiske og opportunistiske infektioner

Info

Publication number
DK0907363T3
DK0907363T3 DK97917709T DK97917709T DK0907363T3 DK 0907363 T3 DK0907363 T3 DK 0907363T3 DK 97917709 T DK97917709 T DK 97917709T DK 97917709 T DK97917709 T DK 97917709T DK 0907363 T3 DK0907363 T3 DK 0907363T3
Authority
DK
Denmark
Prior art keywords
amino
methylquinoline
dichlorophenoxy
methylbutyl
parasitic
Prior art date
Application number
DK97917709T
Other languages
English (en)
Inventor
James D Mcchesney
Dhammika N P Nanayakkara
Marilyn Bartlett
Arba L Ager
Original Assignee
Univ Mississippi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mississippi filed Critical Univ Mississippi
Application granted granted Critical
Publication of DK0907363T3 publication Critical patent/DK0907363T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/40—Nitrogen atoms attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK97917709T 1996-03-29 1997-03-28 Lægemiddel, der omfatter (-)-8-[(4-amino-1-methylbutyl)amino]-5-(3,4-dichlorphenoxy)-6-methoxy-4-methylquinolin, til behandling af parasitiske og opportunistiske infektioner DK0907363T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1429296P 1996-03-29 1996-03-29
PCT/US1997/005160 WO1997036590A1 (en) 1996-03-29 1997-03-28 8-aminoquinolines

Publications (1)

Publication Number Publication Date
DK0907363T3 true DK0907363T3 (da) 2007-09-24

Family

ID=21764604

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97917709T DK0907363T3 (da) 1996-03-29 1997-03-28 Lægemiddel, der omfatter (-)-8-[(4-amino-1-methylbutyl)amino]-5-(3,4-dichlorphenoxy)-6-methoxy-4-methylquinolin, til behandling af parasitiske og opportunistiske infektioner

Country Status (11)

Country Link
US (1) US6376511B2 (da)
EP (1) EP0907363B1 (da)
AT (1) ATE362762T1 (da)
AU (1) AU729992B2 (da)
CA (1) CA2250501C (da)
DE (1) DE69737749T2 (da)
DK (1) DK0907363T3 (da)
ES (1) ES2284184T3 (da)
NZ (1) NZ332197A (da)
PT (1) PT907363E (da)
WO (1) WO1997036590A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0210150D0 (en) * 2002-05-03 2002-06-12 Smithkline Beecham Plc Process
US6949250B2 (en) * 2002-12-16 2005-09-27 The United States Of America As Represented By The Secretary Of Agriculture Selective algaecides for control of cyanochloronta
WO2007127930A2 (en) * 2006-04-28 2007-11-08 Kansas State University Research Foundation Compounds affecting gap junction activity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB834300A (en) * 1957-03-22 1960-05-04 Wellcome Found Improvements in and relating to quinoline derivatives and the manufacture thereof
US4209519A (en) * 1978-03-13 1980-06-24 The United States Of America As Represented By The Secretary Of The Army Anti-leishmanial lepidine derivatives
US4431807A (en) * 1980-06-12 1984-02-14 The United States Of America As Represented By The Secretary Of The Army 4-Methyl-5-(unsubstituted and substituted phenoxy)-6-methoxy-8-(aminoalkylamino)quinolines
US4659708A (en) * 1980-09-02 1987-04-21 The United States Of America As Represented By The Secretary Of The Army Anti-leishmanial lepidine derivatives
US4554279A (en) * 1981-01-29 1985-11-19 The United States Of America As Represented By The Secretary Of The Army 5-(Straight chain 3-12 carbon alkoxy)-8-quinolinamines and their use for treatment of malaria
US4617394A (en) * 1985-10-15 1986-10-14 The United States Of America As Represented By The Secretary Of The Army 4-methyl-5-(unsubstituted and substituted phenoxy)-2,6-dimethoxy-8-(aminoalkylamino) quinolines
FR2612778B1 (fr) * 1987-03-24 1991-10-18 Ire Cell Targ Sa Nouveaux derives d'aminoquinoleine antimalarique, procede de preparation et composition pharmaceutique en contenant
FR2644462B1 (fr) * 1988-09-23 1993-07-09 Ire Celltarg Sa Nouveaux composes actifs sur les formes tissulaires de la malaria et procede de preparation
US4980360A (en) * 1990-03-13 1990-12-25 Calspan Corporation 5-(phenylalkoxy)primaquine compounds and their use for treatment of malaria
US5104885A (en) * 1990-03-13 1992-04-14 Calspan Corporation 5-(phenylalkoxy)primaquine and 5[(heterocycle)alkoxy] primaquine compounds and their use for treatment of malaria

Also Published As

Publication number Publication date
EP0907363A1 (en) 1999-04-14
US6376511B2 (en) 2002-04-23
US20010007031A1 (en) 2001-07-05
EP0907363A4 (en) 2005-04-06
PT907363E (pt) 2007-06-08
WO1997036590A1 (en) 1997-10-09
EP0907363B1 (en) 2007-05-23
AU2596697A (en) 1997-10-22
AU729992B2 (en) 2001-02-22
DE69737749D1 (de) 2007-07-05
DE69737749T2 (de) 2008-01-31
NZ332197A (en) 2000-06-23
CA2250501C (en) 2007-11-13
ES2284184T3 (es) 2007-11-01
ATE362762T1 (de) 2007-06-15
CA2250501A1 (en) 1997-10-09

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