DK0909175T3 - Ikke-vandige, protiske peptidformuleringer - Google Patents

Ikke-vandige, protiske peptidformuleringer

Info

Publication number: DK0909175T3
Authority: DK; Denmark
Prior art keywords: peptide formulations; aqueous protic; protic peptide; aqueous; formulations
Prior art date: 1996-07-03

Application number

DK97930181T

Other languages

Danish (da)

English (en)

Inventor

James B Eckenhoff

Cynthia L Stevenson

Sally A Tao

Steven J Prestrelski

Jeremy C Wright

Joe Leonard

Original Assignee

Alza Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-03

Filing date

1997-07-01

Publication date

2003-09-29

1997-07-01 Application filed by Alza Corp filed Critical Alza Corp

2003-09-29 Application granted granted Critical

2003-09-29 Publication of DK0909175T3 publication Critical patent/DK0909175T3/da

Links

238000009472 formulation Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
Epidemiology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Gynecology & Obstetrics (AREA)
Dermatology (AREA)
Urology & Nephrology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)
Peptides Or Proteins (AREA)

DK97930181T 1996-07-03 1997-07-01 Ikke-vandige, protiske peptidformuleringer DK0909175T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US2112996P	1996-07-03	1996-07-03
PCT/US1997/010815 WO1998000152A1 (en)	1996-07-03	1997-07-01	Non-aqueous protic peptide formulations

Publications (1)

Publication Number	Publication Date
DK0909175T3 true DK0909175T3 (da)	2003-09-29

Family

ID=21802501

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97930181T DK0909175T3 (da)	1996-07-03	1997-07-01	Ikke-vandige, protiske peptidformuleringer

Country Status (27)

Country	Link
EP (1)	EP0909175B1 (id)
JP (3)	JP2001504802A (id)
CN (1)	CN1231256C (id)
AR (1)	AR008060A1 (id)
AT (1)	ATE241997T1 (id)
AU (1)	AU737664B2 (id)
BR (1)	BR9710130A (id)
CA (1)	CA2259403A1 (id)
CO (1)	CO4890854A1 (id)
CZ (1)	CZ433898A3 (id)
DE (1)	DE69722620T2 (id)
DK (1)	DK0909175T3 (id)
ES (1)	ES2201306T3 (id)
HU (1)	HUP9903942A3 (id)
ID (1)	ID19165A (id)
IL (1)	IL127769A (id)
MY (1)	MY121684A (id)
NO (1)	NO323933B1 (id)
NZ (1)	NZ333580A (id)
PL (1)	PL189402B1 (id)
PT (1)	PT909175E (id)
RO (1)	RO119862B1 (id)
RU (1)	RU2203085C2 (id)
SK (1)	SK284490B6 (id)
TW (1)	TW491703B (id)
WO (1)	WO1998000152A1 (id)
ZA (1)	ZA975942B (id)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2203085C2 (ru) *	1996-07-03	2003-04-27	Элзэ Копэрейшн	Стабильный неводный препарат пептидного соединения, способ его получения и способ лечения гормон-зависимого заболевания у субъекта
US7258869B1 (en)	1999-02-08	2007-08-21	Alza Corporation	Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7919109B2 (en)	1999-02-08	2011-04-05	Intarcia Therapeutics, Inc.	Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
AU2002316811A1 (en)	2001-06-28	2003-03-03	Novo Nordisk A/S	Stable formulation of modified glp-1
US7731947B2 (en)	2003-11-17	2010-06-08	Intarcia Therapeutics, Inc.	Composition and dosage form comprising an interferon particle formulation and suspending vehicle
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
DE602004031011D1 (de) *	2003-04-25	2011-02-24	Boston Scient Scimed Inc	Feste arzneimittelformulierung und vorrichtung zu ihrer aufbewahrung und kontrollierten abgabe
TR201906789T4 (tr) *	2003-11-20	2019-05-21	Novo Nordisk As	Üretim ve enjeksiyon cihazlarında kullanım için en uygun olan propilen glikol ihtiva eden peptit formülasyonları.
US11246913B2 (en)	2005-02-03	2022-02-15	Intarcia Therapeutics, Inc.	Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en)	2005-02-03	2006-08-10	Alza Corporation	Solvent/polymer solutions as suspension vehicles
MX2008014870A (es)	2006-05-30	2009-02-12	Intarcia Therapeutics Inc	Modulador de flujo para sistema de suministro osmotico con canal interno de dos piezas.
EP2049081B1 (en)	2006-08-09	2012-11-14	Intarcia Therapeutics, Inc.	Osmotic delivery systems and piston assemblies
US20080275030A1 (en)	2007-01-19	2008-11-06	Sveinbjorn Gizurarson	Methods and Compositions for the Delivery of a Therapeutic Agent
CN101678112B (zh) *	2007-01-19	2016-08-31	哈南亚有限公司	用于递送治疗剂的方法和组合物
AU2013203271B2 (en) *	2007-01-19	2016-05-12	Hananja Ehf	Methods and compositions for the delivery of a therapeutic agent
HRP20130259T1 (hr)	2007-04-23	2013-04-30	Intarcia Therapeutics, Inc.	Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe
EP2170283B1 (en)	2007-06-22	2019-01-09	Board of Regents, The University of Texas System	Formation of stable submicron peptide or protein particles by thin film freezing
DK2240155T3 (da)	2008-02-13	2012-09-17	Intarcia Therapeutics Inc	Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
CA2730760A1 (en)	2008-07-16	2010-01-21	Surmodics Pharmaceuticals, Inc.	Process for preparing microparticles containing bioactive peptides
CN117530912A (zh)	2008-08-15	2024-02-09	硬木药品公司	适合口服给药的鸟苷酸环化酶-c受体激动剂多肽的稳定的固体制剂
EP2376522A4 (en)	2008-11-16	2013-12-25	Univ Texas	LOW VISCOSIS HIGHLY CONCENTRATED SUSPENSIONS
CA2770077A1 (en)	2009-08-06	2011-02-10	Ironwood Pharmaceuticals, Inc.	Formulations comprising linaclotide
SMT201700583T1 (it)	2009-09-28	2018-01-11	Intarcia Therapeutics Inc	Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario
US8933030B2 (en)	2010-02-17	2015-01-13	Ironwwod Pharmaceuticals, Inc.	Treatments for gastrointestinal disorders
DK2603232T3 (da)	2010-08-11	2019-12-09	Ironwood Pharmaceuticals Inc	Stabile formuleringer af linaclotid
US20120208755A1 (en)	2011-02-16	2012-08-16	Intarcia Therapeutics, Inc.	Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9708371B2 (en)	2011-08-17	2017-07-18	Ironwood Pharmaceuticals, Inc.	Treatments for gastrointestinal disorders
JP2013231030A (ja) *	2012-04-30	2013-11-14	Sun Pharmaceutical Industries Ltd	リュープロリド注射剤
US9956287B2 (en)	2013-02-06	2018-05-01	Perosphere Inc.	Stable glucagon formulations
EP2823808A1 (en) *	2013-07-09	2015-01-14	Ipsen Pharma S.A.S.	Pharmaceutical composition for a sustained release of lanreotide
US9889085B1 (en)	2014-09-30	2018-02-13	Intarcia Therapeutics, Inc.	Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10925639B2 (en)	2015-06-03	2021-02-23	Intarcia Therapeutics, Inc.	Implant placement and removal systems
RU2760007C2 (ru)	2016-05-16	2021-11-22	Интарсия Терапьютикс, Инк.	Полипептиды, селективные к рецепторам глюкагона, и способы их применения
USD840030S1 (en)	2016-06-02	2019-02-05	Intarcia Therapeutics, Inc.	Implant placement guide
USD860451S1 (en)	2016-06-02	2019-09-17	Intarcia Therapeutics, Inc.	Implant removal tool
CN110225762A (zh)	2017-01-03	2019-09-10	因塔西亚制药公司	包括glp-1受体激动剂的连续施用和药物的共同施用的方法
EP3372224A1 (en)	2017-03-07	2018-09-12	Alrise Biosystems GmbH	New controlled drug delivery system using water miscible solvents for production of drug loaded micro- and nanoparticles
HRP20240485T1 (hr)	2017-08-24	2024-07-05	Novo Nordisk A/S	Pripravci glp-1 i njihova upotreba
PE20230819A1 (es)	2020-02-18	2023-05-19	Novo Nordisk As	Composiciones y usos de glp-1

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4897256A (en) *	1986-11-25	1990-01-30	Abbott Laboratories	LHRH analog formulations
ATE99543T1 (de) *	1987-10-15	1994-01-15	Syntex Inc	Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden.
US4980163A (en) *	1989-03-01	1990-12-25	Public Health Research Institute Of The City Of New York	Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection
US5158761A (en) *	1989-04-05	1992-10-27	Toko Yakuhin Kogyo Kabushiki Kaisha	Spray gel base and spray gel preparation using thereof
IT1237197B (it) *	1989-11-16	1993-05-26	Sclavo Spa	Formulazioni farmaceutiche anidre e forme di dosaggio per la somministrazione rettale di calcitonina.
RU2008354C1 (ru) *	1991-03-13	1994-02-28	Данилевич Василий Николаевич	Способ хранения препарата протеиназ
ES2107051T3 (es) *	1992-09-21	1997-11-16	Upjohn Co	Formulaciones de proteinas de liberacion sostenida.
DE69426292T2 (de) *	1993-02-23	2001-05-17	Genentech, Inc.	Stabilisierung von mit organischen lösungsmittel behandelten polypeptiden mit einem hilfsstoff
US5955430A (en) *	1993-09-24	1999-09-21	University Of Southern California	Use of angiotensin II fragments and analogs thereof in tissue repair
JP3597233B2 (ja) *	1993-10-21	2004-12-02	久光製薬株式会社	経鼻組成物及びそれを含有する経鼻製剤
RU2203085C2 (ru) *	1996-07-03	2003-04-27	Элзэ Копэрейшн	Стабильный неводный препарат пептидного соединения, способ его получения и способ лечения гормон-зависимого заболевания у субъекта

1997
- 1997-07-01 RU RU99102540/14A patent/RU2203085C2/ru not_active IP Right Cessation
- 1997-07-01 AU AU34073/97A patent/AU737664B2/en not_active Ceased
- 1997-07-01 EP EP97930181A patent/EP0909175B1/en not_active Expired - Lifetime
- 1997-07-01 DE DE69722620T patent/DE69722620T2/de not_active Expired - Lifetime
- 1997-07-01 RO RO98-01769A patent/RO119862B1/ro unknown
- 1997-07-01 WO PCT/US1997/010815 patent/WO1998000152A1/en not_active Ceased
- 1997-07-01 SK SK1799-98A patent/SK284490B6/sk not_active IP Right Cessation
- 1997-07-01 CN CNB971960534A patent/CN1231256C/zh not_active Expired - Fee Related
- 1997-07-01 NZ NZ333580A patent/NZ333580A/en not_active IP Right Cessation
- 1997-07-01 JP JP50421898A patent/JP2001504802A/ja not_active Withdrawn
- 1997-07-01 ES ES97930181T patent/ES2201306T3/es not_active Expired - Lifetime
- 1997-07-01 PT PT97930181T patent/PT909175E/pt unknown
- 1997-07-01 CZ CZ984338A patent/CZ433898A3/cs unknown
- 1997-07-01 HU HU9903942A patent/HUP9903942A3/hu unknown
- 1997-07-01 DK DK97930181T patent/DK0909175T3/da active
- 1997-07-01 PL PL97330869A patent/PL189402B1/pl not_active IP Right Cessation
- 1997-07-01 CA CA002259403A patent/CA2259403A1/en not_active Abandoned
- 1997-07-01 BR BR9710130A patent/BR9710130A/pt not_active Application Discontinuation
- 1997-07-01 AT AT97930181T patent/ATE241997T1/de active
- 1997-07-01 IL IL127769A patent/IL127769A/en not_active IP Right Cessation
- 1997-07-02 AR ARP970102967A patent/AR008060A1/es unknown
- 1997-07-03 ID IDP972315A patent/ID19165A/id unknown
- 1997-07-03 CO CO97037097A patent/CO4890854A1/es unknown
- 1997-07-03 ZA ZA9705942A patent/ZA975942B/xx unknown
- 1997-07-03 MY MYPI97003024A patent/MY121684A/en unknown
- 1997-08-22 TW TW086109392A patent/TW491703B/zh not_active IP Right Cessation
1998
- 1998-12-30 NO NO19986209A patent/NO323933B1/no not_active IP Right Cessation
2008
- 2008-04-23 JP JP2008112307A patent/JP2008195739A/ja active Pending
2009
- 2009-10-05 JP JP2009231256A patent/JP2010043105A/ja active Pending

Also Published As

Publication number	Publication date
MY121684A (en)	2006-02-28
JP2001504802A (ja)	2001-04-10
NO986209D0 (no)	1998-12-30
NZ333580A (en)	2000-06-23
CO4890854A1 (es)	2000-02-28
PL330869A1 (en)	1999-06-07
AR008060A1 (es)	1999-12-09
ZA975942B (en)	1998-04-16
IL127769A0 (en)	1999-10-28
AU737664B2 (en)	2001-08-30
TW491703B (en)	2002-06-21
ID19165A (id)	1998-06-28
EP0909175A1 (en)	1999-04-21
CN1224356A (zh)	1999-07-28
SK179998A3 (en)	1999-05-07
PL189402B1 (pl)	2005-08-31
CN1231256C (zh)	2005-12-14
RU2203085C2 (ru)	2003-04-27
DE69722620T2 (de)	2004-04-29
EP0909175B1 (en)	2003-06-04
BR9710130A (pt)	1999-08-10
NO323933B1 (no)	2007-07-23
PT909175E (pt)	2003-10-31
HUP9903942A2 (hu)	2000-04-28
WO1998000152A1 (en)	1998-01-08
NO986209L (no)	1998-12-30
IL127769A (en)	2006-10-31
CA2259403A1 (en)	1998-01-08
JP2010043105A (ja)	2010-02-25
ES2201306T3 (es)	2004-03-16
RO119862B1 (ro)	2005-05-30
CZ433898A3 (cs)	1999-04-14
SK284490B6 (sk)	2005-05-05
DE69722620D1 (de)	2003-07-10
AU3407397A (en)	1998-01-21
HUP9903942A3 (en)	2000-07-28
JP2008195739A (ja)	2008-08-28
ATE241997T1 (de)	2003-06-15

Publication	Publication Date	Title
DK0909175T3 (da)	2003-09-29	Ikke-vandige, protiske peptidformuleringer
DK0921808T3 (da)	2003-01-27	Ikke-vandige, polære aprotiske peptidformuleringer
NO982097D0 (no)	1998-05-08	Peptider
NO982098L (no)	1999-11-09	Peptider
FI102434B (fi)	1998-11-30	Kahden taajuuden antenni
DE59711355D1 (de)	2004-04-08	Aktive Empfangsantenne
DE59708688D1 (de)	2002-12-19	Trennschalter
NO985680L (no)	1999-02-04	Peptidderivater
EA200000208A1 (ru)	2000-08-28	Иммуномодулятор с антимикробной и антимикобактериальной активностью, способ его получения и лекарственный препарат для лечения микобактериозов, хронических неспецифических заболеваний легких, заболеваний, передающихся половым путем, и иммунодефицита на их основе
NO983849L (no)	1998-10-21	Peptidderivater
NO985930L (no)	1999-02-15	Katodekonstruksjon
NO962167D0 (no)	1996-05-28	Deflektoranordning
NO965214D0 (no)	1996-12-06	Deflektor
DE69704741D1 (de)	2001-06-13	Schwimmflosse
DE69736371D1 (de)	2006-09-07	Bieten um Bandbreite
NO20012283D0 (no)	2001-05-09	Koblede peptider
DE69813938D1 (de)	2003-06-05	Schaltröhre
NL1008516A1 (nl)	1998-09-14	Korstenbreker.
FI963062A0 (fi)	1996-08-02	Dubbelblad foer stoetblad, skopa, schaktblad
SE9802536D0 (sv)	1998-07-13	Novel peptides
NL1010046A1 (nl)	1999-03-15	Sproeistation.
TR199600559U (tr)	1996-10-21	Korumali kontaktör.
IT1294319B1 (it)	1999-03-24	Struttura di sci, snowboard o simile
BR7602376U (pt)	1998-09-22	Disposição construtiva de antenas
ES1033732Y (es)	1997-03-01	Aplique.