DK0909562T3 - Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf - Google Patents

Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf

Info

Publication number: DK0909562T3
Authority: DK; Denmark
Prior art keywords: preparation; lipid; analog; injection; preparing
Prior art date: 1996-07-03

Application number

DK97929518T

Other languages

English (en)

Inventor

Yasuyuki Asai

Katsumi Onai

Kazuhide Ashizawa

Kiyoshi Iwamoto

Yasuo Ishibashi

Sumio Watanabe

Original Assignee

Eisai Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-03

Filing date

1997-07-03

Publication date

2005-08-22

1997-07-03 Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd

2005-08-22 Application granted granted Critical

2005-08-22 Publication of DK0909562T3 publication Critical patent/DK0909562T3/da

Links

238000002347 injection Methods 0.000 title abstract 3
239000007924 injection Substances 0.000 title abstract 3
GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical class O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 title abstract 3
238000000034 method Methods 0.000 title 1
238000004519 manufacturing process Methods 0.000 abstract 2
239000007864 aqueous solution Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Inorganic Chemistry (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK97929518T 1996-07-03 1997-07-03 Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf DK0909562T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP17361596		1996-07-03
EP97929518A EP0909562B1 (en)	1996-07-03	1997-07-03	Injections containing lipid a analogues and process for the preparation thereof

Publications (1)

Publication Number	Publication Date
DK0909562T3 true DK0909562T3 (da)	2005-08-22

Family

ID=15963903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97929518T DK0909562T3 (da)	1996-07-03	1997-07-03	Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf

Country Status (9)

Country	Link
US (1)	US6235724B1 (da)
EP (1)	EP0909562B1 (da)
CN (1)	CN1150001C (da)
AT (1)	ATE298578T1 (da)
CA (1)	CA2259520C (da)
DE (1)	DE69733651T2 (da)
DK (1)	DK0909562T3 (da)
ES (1)	ES2242226T3 (da)
WO (1)	WO1998001139A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU7799198A (en) *	1997-05-23	1998-12-21	Eisai Co. Ltd.	Method for preparing pharmaceutical formulation
EP1096954B1 (en) *	1998-07-14	2004-10-06	Wyeth Holdings Corporation	Adjuvant and vaccine compositions containing monophosphoryl lipid a
US6306404B1 (en)	1998-07-14	2001-10-23	American Cyanamid Company	Adjuvant and vaccine compositions containing monophosphoryl lipid A
US6635261B2 (en)	1999-07-13	2003-10-21	Wyeth Holdings Corporation	Adjuvant and vaccine compositions containing monophosphoryl lipid A
EP2452684B1 (en)	2000-02-18	2018-01-24	Eisai R&D Management Co., Ltd.	Micelles
SI2266603T1 (sl)	2000-10-18	2012-12-31	Glaxosmithkline Biologicals S.A.	Tumorska cepiva
WO2002094019A1 (en) *	2001-05-22	2002-11-28	Eisai Co., Ltd	Highly purified antiendotoxin compound
PL2068918T5 (pl)	2006-09-26	2024-12-02	Access To Advanced Health Institute	Kompozycja szczepionki zawierająca syntetyczny adiuwant
US20090181078A1 (en)	2006-09-26	2009-07-16	Infectious Disease Research Institute	Vaccine composition containing synthetic adjuvant
CA2735724C (en)	2008-06-19	2018-07-24	Variation Biotechnologies Inc.	Compositions and methods for treating influenza
CA2764374C (en)	2009-06-05	2019-11-19	Infectious Disease Research Institute	Synthetic glucopyranosyl lipid adjuvants
CA2803282C (en)	2009-07-06	2018-05-01	David E. Anderson	Methods for preparing vesicles and formulations produced therefrom
JP5854559B2 (ja)	2009-07-06	2016-02-09	ヴァリエーションバイオテクノロジーズインコーポレイテッド	小胞を調製する方法及びこれから製造される製剤
WO2012006367A2 (en)	2010-07-06	2012-01-12	Variation Biotechnologies, Inc.	Compositions and methods for treating influenza
BR112013018074A2 (pt)	2011-01-13	2020-12-01	Variation Biotechnologies, Inc.	métodos para a preparação de vesículas e formulações produzidas a partir dessas
US10736844B2 (en)	2011-01-13	2020-08-11	Variation Biotechnologies Inc.	Compositions and methods for treating viral infections
EA027236B1 (ru)	2011-04-08	2017-07-31	Иммьюн Дизайн Корп.	Иммуногенные композиции и способы применения таких композиций для индукции гуморального и клеточного иммунного ответа
AU2013208693B2 (en)	2012-01-12	2017-12-07	Variation Biotechnologies Inc.	Compositions and methods for treating viral infections
EP2806894A4 (en)	2012-01-27	2015-11-04	Variation Biotechnologies Inc	METHODS AND COMPOSITIONS FOR THERAPEUTIC AGENTS
HRP20181102T1 (hr)	2012-05-16	2018-09-07	Immune Design Corp	Cjepiva za hsv-2
MX370573B (es)	2013-04-18	2019-12-17	Immune Design Corp	Monoterapia con glucopiranosil lipido a para usarse en el tratamiento del cancer.
US9463198B2 (en)	2013-06-04	2016-10-11	Infectious Disease Research Institute	Compositions and methods for reducing or preventing metastasis
EP3242883A4 (en)	2015-01-06	2018-10-17	ImmunoVaccine Technologies Inc.	Lipid a mimics, methods of preparation, and uses thereof
WO2019051149A1 (en)	2017-09-08	2019-03-14	Infectious Disease Research Institute	LIPOSOMAL FORMULATIONS COMPRISING SAPONIN AND METHODS OF USE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1216686B (it)	1988-04-01	1990-03-08	Chiesi Farma Spa	Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
JPH04198192A (ja) *	1990-11-28	1992-07-17	Japan Tobacco Inc	リピッドａ類縁体の水溶液
AU660325B2 (en) *	1991-10-11	1995-06-22	Eisai Co. Ltd.	Anti-endotoxin compounds and related molecules and methods
US5530113A (en) *	1991-10-11	1996-06-25	Eisai Co., Ltd.	Anti-endotoxin compounds
US5681824A (en) *	1995-06-05	1997-10-28	Eisai Co., Ltd.	Substituted liposaccharides useful in the treatment and prevention of endotoxemia

1997
- 1997-07-03 AT AT97929518T patent/ATE298578T1/de active
- 1997-07-03 EP EP97929518A patent/EP0909562B1/en not_active Expired - Lifetime
- 1997-07-03 DE DE69733651T patent/DE69733651T2/de not_active Expired - Lifetime
- 1997-07-03 DK DK97929518T patent/DK0909562T3/da active
- 1997-07-03 WO PCT/JP1997/002316 patent/WO1998001139A1/ja not_active Ceased
- 1997-07-03 ES ES97929518T patent/ES2242226T3/es not_active Expired - Lifetime
- 1997-07-03 US US09/194,704 patent/US6235724B1/en not_active Expired - Fee Related
- 1997-07-03 CA CA002259520A patent/CA2259520C/en not_active Expired - Fee Related
- 1997-07-03 CN CNB971960518A patent/CN1150001C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2259520A1 (en)	1998-01-15
DE69733651D1 (de)	2005-08-04
EP0909562B1 (en)	2005-06-29
CN1224355A (zh)	1999-07-28
ES2242226T3 (es)	2005-11-01
ATE298578T1 (de)	2005-07-15
EP0909562A1 (en)	1999-04-21
WO1998001139A1 (fr)	1998-01-15
CN1150001C (zh)	2004-05-19
DE69733651T2 (de)	2006-05-18
EP0909562A4 (en)	1999-12-29
US6235724B1 (en)	2001-05-22
CA2259520C (en)	2007-09-11

Publication	Publication Date	Title
DK0909562T3 (da)	2005-08-22	Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf
NL300181I1 (nl)	2005-05-02	N-(pyrroloÄ2,3-dÜpyrimidine-3-ylacyl)-glutaminezuurderivaten.
FI905500A0 (fi)	1990-11-06	Individualiserade, med polykarboxylsyra tvaerbundna fibrer.
NO871333L (no)	1987-10-01	Kinolin-3-karboksylsyrederivater, fremgangsmaate til fremstilling og anvendelse derav.
DE3874493D1 (de)	1992-10-15	Optischer positionssensor, den faraday-effekt benutzend.
TR199800077T1 (xx)	1998-05-21	Kontroll� ��z�len paroksetin terkipleri.
DK15089D0 (da)	1989-01-13	Aminofunktionelle forbindelser, fremgangsmaade til fremstilling heraf samt vaskemidler omfattende samme.
FI903028A0 (fi)	1990-06-15	Polymerbaserade blandningskompositioner, som innehaoller destrukturerad staerkelse.
NO903757L (no)	1991-03-01	Kitin.kitosan-oligomer med 2,5-anhydromannitol endegruppeeller 2,5-anhydromannose endegruppe og fremgangsmaate til fremstilling derav.
DE69019572D1 (de)	1995-06-29	Gasauflösung.
NO894549D0 (no)	1989-11-15	Titandioksyd, fremgangsmaate for fremstilling derav og anvendelse derav.
DE69006896D1 (de)	1994-04-07	Makromolekulares endoplasmatisches Retikulum.
TR200001102T2 (tr)	2000-08-21	İkameli tetrahidropirimidinen türevleri, üretimleri ve kullanımları.
NO901533L (no)	1990-10-08	Aminosyrederivater.
NO903780D0 (no)	1990-08-29	Fremgangsmaate til fremstilling av epipodofyllotoksinaltrosid-derivater.
FI893605A0 (fi)	1989-07-28	Imidatso (4,5-b) pyridinderivat.
FR2662064B3 (fr)	1992-05-15	Structure de mannequin destinee en particulier a des articles de vetement.
FI905020A0 (fi)	1990-10-12	Orala kompositioner, som innehaoller monoperoxisyror.
FI913179A7 (fi)	1991-12-29	Aminosyraderivat.
NO954442D0 (no)	1995-11-06	Bicyklopolyazamakrocyklofosfonsyrer, deres komplekser og konjugater, for anvendelse som kontrastmidler, og fremgangsmåter for deres fremstilling
EP0636611A3 (en)	1995-03-01	Optically active 1,4-dihydropyridine derivatives and process for preparing the same.
NO900252D0 (no)	1990-01-18	Cefasporinderivater og fremgangsmaate for fremstilling derav.
NO905244D0 (no)	1990-12-04	Fremgangsmaate for fremstilling av des(64,65)-proinsulin.
DK191290D0 (da)	1990-08-10	Extracellulaer exopolymer, fremgangsmaade til fremstilling af samme og farmaceutiske praeparater indeholdende exopolymeren
NO904034D0 (no)	1990-09-17	Fremgangsmaate for fremstilling av 1-etylfenoksatiin-10,10-dioksyd.