DK0914103T3 - Behandling af hæmoglobinopati - Google Patents

Behandling af hæmoglobinopati

Info

Publication number
DK0914103T3
DK0914103T3 DK97920137T DK97920137T DK0914103T3 DK 0914103 T3 DK0914103 T3 DK 0914103T3 DK 97920137 T DK97920137 T DK 97920137T DK 97920137 T DK97920137 T DK 97920137T DK 0914103 T3 DK0914103 T3 DK 0914103T3
Authority
DK
Denmark
Prior art keywords
hemoglobinopathy
treatment
Prior art date
Application number
DK97920137T
Other languages
Danish (da)
English (en)
Inventor
Warren M Zapol
C Alvin Head
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of DK0914103T3 publication Critical patent/DK0914103T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/295—Iron group metal compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK97920137T 1996-04-05 1997-04-03 Behandling af hæmoglobinopati DK0914103T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1488696P 1996-04-05 1996-04-05

Publications (1)

Publication Number Publication Date
DK0914103T3 true DK0914103T3 (da) 2006-10-23

Family

ID=21768361

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97920137T DK0914103T3 (da) 1996-04-05 1997-04-03 Behandling af hæmoglobinopati

Country Status (15)

Country Link
US (1) US5885621A (de)
EP (1) EP0914103B1 (de)
JP (1) JP2000510448A (de)
CN (1) CN1208053C (de)
AP (1) AP897A (de)
AT (1) ATE331505T1 (de)
AU (1) AU720686B2 (de)
BR (1) BR9708601A (de)
CA (1) CA2251530C (de)
DE (1) DE69736230T2 (de)
DK (1) DK0914103T3 (de)
ES (1) ES2267141T3 (de)
OA (1) OA10893A (de)
PT (1) PT914103E (de)
WO (1) WO1997037644A1 (de)

Families Citing this family (60)

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US6063407A (en) * 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US6627738B2 (en) 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
US6197745B1 (en) 1995-09-15 2001-03-06 Duke University Methods for producing nitrosated hemoglobins and therapeutic uses therefor
US6911427B1 (en) 1995-09-15 2005-06-28 Duke University No-modified hemoglobins and uses therefore
US8128963B2 (en) * 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
US6656452B1 (en) 1997-10-21 2003-12-02 The General Hospital Corporation Use of inhaled NO as anti-inflammatory agent
US20070086954A1 (en) * 1998-11-23 2007-04-19 Miller Christopher C Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
CA2254645A1 (en) * 1998-11-23 2000-05-23 Pulmonox Medical Corporation Method and apparatus for treatment of respiratory infections by nitric oxide inhalation
US7678390B2 (en) 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
FR2794647A1 (fr) * 1999-06-11 2000-12-15 Centre Nat Rech Scient Compositions pharmaceutique comprenant du no ou au moins un compose capable de liberer ou d'induire la formation de no dans les cellules
US7516742B2 (en) * 1999-11-24 2009-04-14 Cardinal Health 207, Inc. Method and apparatus for delivery of inhaled nitric oxide to spontaneous-breathing and mechanically-ventilated patients with intermittent dosing
US6601580B1 (en) 2000-06-28 2003-08-05 The General Hospital Corporation Enhancing therapeutic effectiveness of nitric oxide inhalation
FR2812197B1 (fr) * 2000-07-27 2003-01-03 Air Liquide Sante Int Utilisation de co dans le traitement de l'inflammation des voies aeriennes superieures ou des bronches
FR2816212A1 (fr) * 2000-11-03 2002-05-10 Air Liquide Sante Int Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire
US6432077B1 (en) * 2000-12-26 2002-08-13 Sensormedics Corporation Device and method for treatment of surface infections with nitric oxide
US7335181B2 (en) * 2000-12-26 2008-02-26 Pulmonox Technologies Corporation Nitric oxide decontamination of the upper respiratory tract
US7122018B2 (en) * 2000-12-26 2006-10-17 Sensormedics Corporation Device and method for treatment of wounds with nitric oxide
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
SK15942003A3 (sk) * 2001-06-21 2004-08-03 Beth Israel Deaconess Medical Center, Inc. Farmaceutická kompozícia s obsahom oxidu uhoľnatého zlepšujúca prežívanie alebo funkciu orgánov po transplantácii
GB0125222D0 (en) * 2001-10-19 2001-12-12 Barts & London Nhs Trust Composition for the treatment of microbial infections
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
EP2042181A1 (de) * 2002-02-04 2009-04-01 ALFAMA-Investigacao e Desenvolvimento de Produtos Farmaceuticos Lda. Verwendung CO- freisetzender Substanzen zur Herstellung eines Medikaments für die Behandlung entzündlicher Erkrankungen
US7364757B2 (en) * 2002-02-13 2008-04-29 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating vascular disease
HRP20040972A2 (en) * 2002-04-15 2005-06-30 University Of Pittsburgh Of The Commonwealth Systeyale University Methods of treating ileus
AU2003223562B2 (en) * 2002-04-15 2009-04-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating necrotizing enterocolitis
JP2005522521A (ja) 2002-04-15 2005-07-28 ベス イスラエル デアコネス メディカル センター ヘムオキシゲナーゼ−１およびヘム分解産物の使用法
DK1505990T3 (da) 2002-05-17 2011-11-21 Univ Yale Fremgangsmåder til behandling af hepatitis
PL374375A1 (en) * 2002-06-05 2005-10-17 Yale University Methods of treating angiogenesis, tumor growth, and metastasis
CA2490392A1 (en) * 2002-06-21 2003-12-31 University Of Pittsburgh Of The Commonwealth System Of Higher Education Pharmaceutical use of nitric oxide, heme oxygenase-1 and products of heme degradation
US7531133B2 (en) * 2002-09-10 2009-05-12 Pulmonox Technologies Corporation Use of nitric oxide gas in an extracorporeal circuitry to treat blood plasma
MXPA05004924A (es) * 2002-11-07 2005-08-18 Univ Pittsburgh Tratamiento para shock hemorragico.
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
JP5564157B2 (ja) * 2003-07-09 2014-07-30 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ アズ リプレゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ 心臓血管状態の処置のための亜硝酸塩の使用方法
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas
US8518457B2 (en) * 2004-05-11 2013-08-27 Pulmonox Technologies Corporation Use of inhaled gaseous nitric oxide as a mucolytic agent or expectorant
CN1950120B (zh) * 2004-05-11 2010-10-20 伟亚医疗森迪斯公司 一氧化氮气体的间歇计量
US7362274B1 (en) * 2004-07-09 2008-04-22 Huan-Cheng Lien Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
US20070154570A1 (en) * 2004-09-29 2007-07-05 Miller Christopher C Use of nitric oxide in the treatment and disinfection of biofilms
WO2006125123A2 (en) * 2005-05-19 2006-11-23 University Of Cincinnati Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
US7523752B2 (en) * 2005-09-21 2009-04-28 Ino Therapeutics, Llc System and method of administering a pharmaceutical gas to a patient
US8893717B2 (en) 2005-09-21 2014-11-25 Ino Therapeutics Llc Systems and methods of administering a pharmaceutical gas to a patient
WO2007057763A2 (en) * 2005-11-18 2007-05-24 Pulmonox Technologies Corporation Nitric oxide as an anti-viral agent, vaccine and vaccine adjuvant
WO2007073226A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
US8079998B2 (en) * 2006-10-20 2011-12-20 Pulmonox Technologies Corporation Methods and devices for the delivery of therapeutic gases including nitric oxide
EP2099463B1 (de) * 2006-11-07 2014-07-16 The General Hospital Corporation Minderung von vasoaktiver sauerstoffträger-induzierter gefässverengung
US20080193566A1 (en) * 2007-02-09 2008-08-14 Miller Christopher C Use of high dose concentrations of gaseous nitric oxide
US20090196930A1 (en) * 2007-12-27 2009-08-06 Aires Pharmaceuticals, Inc. Aerosolized nitrite and nitric oxide -donating compounds and uses thereof
CN105214193B (zh) 2009-05-27 2017-11-17 马林克罗特医疗产品知识产权公司 用于药物递送调节装置的分度药物收容装置组件及分度药物递送系统
CA3130908A1 (en) 2009-06-30 2010-12-30 Mallinckrodt Hospital Products IP Limited Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension
US20120201906A1 (en) * 2009-09-08 2012-08-09 Reynolds James D Novel medical uses for no and no donor compounds
US9163044B2 (en) 2011-04-19 2015-10-20 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
WO2013013179A1 (en) 2011-07-21 2013-01-24 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
EP3650408A1 (de) 2011-10-03 2020-05-13 NitricGen, Inc. Vorrichtung und verfahren zur erzeugung von stickoxid in kontrollierten und genauen mengen
EP2776047A4 (de) * 2011-11-07 2015-07-22 Gen Hospital Corp Behandlung von erythrozyten
EP3421042B1 (de) 2012-03-07 2024-04-17 Beyond Air Ltd Inhalation von stickoxid zur behandlung von atemwegserkrankungen
MX368858B (es) 2012-03-15 2019-10-18 Mallinckrodt Hospital Products Ip Ltd Metodos para administrar altas concentraciones de oxido nitrico.
US12089930B2 (en) 2018-03-05 2024-09-17 Marquette University Method and apparatus for non-invasive hemoglobin level prediction
US11779720B2 (en) 2019-11-04 2023-10-10 Vapotherm, Inc. Methods, devices, and systems for improved oxygenation patient monitoring, mixing, and delivery

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
US4954526A (en) * 1989-02-28 1990-09-04 The United States Of America As Represented By The Department Of Health And Human Services Stabilized nitric oxide - primary amine complexes useful as cardiovascular agents
US5380945A (en) * 1989-06-21 1995-01-10 Abbott Laboratories Guanidino compounds as regulators of nitric oxide synthase
US5155137A (en) * 1990-09-20 1992-10-13 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complexes of nitric oxide with polyamines
DE122007000103I1 (de) * 1990-12-05 2008-04-03 Gen Hospital Corp Verwendung von NO zur Behandlung der persistenten pulmonalen Hypertonie des Neugeborenen
JPH09508097A (ja) * 1993-11-02 1997-08-19 アメリカ合衆国 虚血再灌流傷害における保護剤としての酸化窒素放出化合物の使用

Also Published As

Publication number Publication date
OA10893A (en) 2001-10-11
CN1208053C (zh) 2005-06-29
EP0914103A1 (de) 1999-05-12
ATE331505T1 (de) 2006-07-15
AP897A (en) 2000-11-17
AP9801358A0 (en) 1998-12-31
CA2251530C (en) 2002-11-19
CA2251530A1 (en) 1997-10-16
EP0914103A4 (de) 2003-09-03
DE69736230D1 (de) 2006-08-10
EP0914103B1 (de) 2006-06-28
JP2000510448A (ja) 2000-08-15
US5885621A (en) 1999-03-23
AU720686B2 (en) 2000-06-08
CN1227485A (zh) 1999-09-01
ES2267141T3 (es) 2007-03-01
PT914103E (pt) 2006-09-29
AU2440397A (en) 1997-10-29
WO1997037644A1 (en) 1997-10-16
DE69736230T2 (de) 2007-05-31
BR9708601A (pt) 1999-08-03

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