DK0914437T3 - Identificering og kloning af et mykobakterieantigen svarende til et heparinbindende hæmagglutinin - Google Patents
Identificering og kloning af et mykobakterieantigen svarende til et heparinbindende hæmagglutininInfo
- Publication number
- DK0914437T3 DK0914437T3 DK97925109T DK97925109T DK0914437T3 DK 0914437 T3 DK0914437 T3 DK 0914437T3 DK 97925109 T DK97925109 T DK 97925109T DK 97925109 T DK97925109 T DK 97925109T DK 0914437 T3 DK0914437 T3 DK 0914437T3
- Authority
- DK
- Denmark
- Prior art keywords
- features
- mycobacteria
- adhesion
- heparin
- host cells
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 238000010367 cloning Methods 0.000 title 1
- 108010037896 heparin-binding hemagglutinin Proteins 0.000 title 1
- 230000025845 adhesion to host Effects 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 206010062207 Mycobacterial infection Diseases 0.000 abstract 2
- 208000027531 mycobacterial infectious disease Diseases 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 1
- 241001467552 Mycobacterium bovis BCG Species 0.000 abstract 1
- 241000187479 Mycobacterium tuberculosis Species 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000000405 serological effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9606168A FR2748748B1 (fr) | 1996-05-17 | 1996-05-17 | Identification et clonage d'un antigene mycobacterien correspondant a une hemagglutine de liaison a l'heparine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0914437T3 true DK0914437T3 (da) | 2006-10-02 |
Family
ID=9492234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97925109T DK0914437T3 (da) | 1996-05-17 | 1997-05-20 | Identificering og kloning af et mykobakterieantigen svarende til et heparinbindende hæmagglutinin |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0914437B1 (de) |
| AT (1) | ATE328085T1 (de) |
| AU (1) | AU3036297A (de) |
| DE (1) | DE69736000T2 (de) |
| DK (1) | DK0914437T3 (de) |
| ES (1) | ES2267142T3 (de) |
| FR (1) | FR2748748B1 (de) |
| PT (1) | PT914437E (de) |
| WO (1) | WO1997044463A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2793492A1 (fr) * | 1999-05-11 | 2000-11-17 | Pasteur Institut | Nouveau procede de purification par affinite |
| US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
| FR2832410B1 (fr) | 2001-11-19 | 2004-04-02 | Pasteur Institut | Antigene mycobacterien recombinant de type hemagglutinine de liaison a l'heparine methylee, procedes de preparation et compositions immunogenes comprenant un tel antigene |
| WO2004009837A2 (en) * | 2002-07-19 | 2004-01-29 | Arizona Board Of Regents | A high resolution typing system for pathogenic mycobacterium tuberculosum |
| FR2872579B1 (fr) * | 2004-06-30 | 2006-11-24 | Pasteur Institut | Detection de la tuberculose et de l'infection par mycobacterium tuberculosis a l'aide de hbha |
| US8475735B2 (en) | 2004-11-01 | 2013-07-02 | Uma Mahesh Babu | Disposable immunodiagnostic test system |
| WO2010149657A1 (en) | 2009-06-22 | 2010-12-29 | Px Therapeutics | Method for the purification of hbha |
| WO2012038486A1 (en) | 2010-09-21 | 2012-03-29 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Method for obtaining a purified hbha polypeptide or fragment thereof |
| US20120321656A1 (en) * | 2011-06-20 | 2012-12-20 | Matthias Rath | Oligopeptides and their use for treating infectious diseases |
| GB201116248D0 (en) | 2011-09-20 | 2011-11-02 | Glaxosmithkline Biolog Sa | Liposome production using isopropanol |
| EP3551222B1 (de) | 2016-12-07 | 2024-08-07 | GlaxoSmithKline Biologicals SA | Verfahren zur herstellung einer liposomzusammensetzung, die ein saponin umfasst |
| GB201621686D0 (en) | 2016-12-20 | 2017-02-01 | Glaxosmithkline Biologicals Sa | Novel methods for inducing an immune response |
| GB201707700D0 (en) | 2017-05-12 | 2017-06-28 | Glaxosmithkline Biologicals Sa | Dried composition |
| GB2600654B (en) | 2017-05-30 | 2022-11-02 | Glaxosmithkline Biologicals Sa | Novel devices |
| WO2019106192A1 (en) | 2017-12-01 | 2019-06-06 | Glaxosmithkline Biologicals Sa | Saponin purification |
| JP7640473B2 (ja) | 2019-06-05 | 2025-03-05 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | サポニン精製 |
-
1996
- 1996-05-17 FR FR9606168A patent/FR2748748B1/fr not_active Expired - Fee Related
-
1997
- 1997-05-20 WO PCT/FR1997/000886 patent/WO1997044463A2/fr not_active Ceased
- 1997-05-20 DE DE69736000T patent/DE69736000T2/de not_active Expired - Lifetime
- 1997-05-20 ES ES97925109T patent/ES2267142T3/es not_active Expired - Lifetime
- 1997-05-20 EP EP97925109A patent/EP0914437B1/de not_active Expired - Lifetime
- 1997-05-20 PT PT97925109T patent/PT914437E/pt unknown
- 1997-05-20 AU AU30362/97A patent/AU3036297A/en not_active Abandoned
- 1997-05-20 DK DK97925109T patent/DK0914437T3/da active
- 1997-05-20 AT AT97925109T patent/ATE328085T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| AU3036297A (en) | 1997-12-09 |
| DE69736000D1 (de) | 2006-07-06 |
| ATE328085T1 (de) | 2006-06-15 |
| EP0914437B1 (de) | 2006-05-31 |
| EP0914437A2 (de) | 1999-05-12 |
| ES2267142T3 (es) | 2007-03-01 |
| WO1997044463A2 (fr) | 1997-11-27 |
| DE69736000T2 (de) | 2007-01-25 |
| FR2748748B1 (fr) | 1998-11-06 |
| FR2748748A1 (fr) | 1997-11-21 |
| PT914437E (pt) | 2006-10-31 |
| WO1997044463A3 (fr) | 1998-01-29 |
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