DK0914818T3 - Intraoralt hurtigt desintegrerbar tablet - Google Patents

Intraoralt hurtigt desintegrerbar tablet

Info

Publication number
DK0914818T3
DK0914818T3 DK97927372T DK97927372T DK0914818T3 DK 0914818 T3 DK0914818 T3 DK 0914818T3 DK 97927372 T DK97927372 T DK 97927372T DK 97927372 T DK97927372 T DK 97927372T DK 0914818 T3 DK0914818 T3 DK 0914818T3
Authority
DK
Denmark
Prior art keywords
disintegrable tablet
tablet
intraoral fast
fast disintegrable
intraoral
Prior art date
Application number
DK97927372T
Other languages
Danish (da)
English (en)
Inventor
Eiji Hayakawa
Motohiro Ohta
Kunio Ito
Sanji Tokuno
Kiyoshi Morimoto
Yasushi Watanabe
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26412238&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0914818(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of DK0914818T3 publication Critical patent/DK0914818T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
DK97927372T 1996-06-14 1997-06-12 Intraoralt hurtigt desintegrerbar tablet DK0914818T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP15355396 1996-06-14
JP7110797 1997-03-25
PCT/JP1997/002032 WO1997047287A1 (en) 1996-06-14 1997-06-12 Intraorally rapidly disintegrable tablet
EP97927372A EP0914818B1 (de) 1996-06-14 1997-06-12 Im munde schnellzerfallende tablette

Publications (1)

Publication Number Publication Date
DK0914818T3 true DK0914818T3 (da) 2005-07-04

Family

ID=26412238

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97927372T DK0914818T3 (da) 1996-06-14 1997-06-12 Intraoralt hurtigt desintegrerbar tablet

Country Status (13)

Country Link
US (1) US20010014340A1 (de)
EP (2) EP0914818B1 (de)
JP (4) JP3797387B2 (de)
CN (1) CN1154479C (de)
AT (2) ATE297191T1 (de)
AU (1) AU733032C (de)
CA (1) CA2258159C (de)
DE (2) DE69739967D1 (de)
DK (1) DK0914818T3 (de)
EA (1) EA001898B1 (de)
ES (1) ES2243998T3 (de)
PT (1) PT914818E (de)
WO (1) WO1997047287A1 (de)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2258159C (en) * 1996-06-14 2006-03-21 Kyowa Hakko Kogyo Co., Ltd. Intraorally rapidly disintegrable tablet
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US6024981A (en) * 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
JP4568426B2 (ja) * 1998-04-08 2010-10-27 協和発酵キリン株式会社 錠剤の製造方法及び錠剤
JP4568427B2 (ja) * 1998-04-10 2010-10-27 協和発酵キリン株式会社 錠剤の製造方法及び錠剤
KR100554924B1 (ko) 1998-05-18 2006-03-03 다케다 야쿠힌 고교 가부시키가이샤 구강내 붕괴 정제
JP4748627B2 (ja) 1998-07-15 2011-08-17 旭化成ケミカルズ株式会社 賦形剤
KR100536783B1 (ko) 1998-07-28 2005-12-14 다케다 야쿠힌 고교 가부시키가이샤 급속 붕해성 고체 제제
US6368625B1 (en) * 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
JP2000178204A (ja) * 1998-10-05 2000-06-27 Eisai Co Ltd ホスフォジエステラ―ゼ阻害剤を含有する口腔内速崩壊性錠剤
FR2790387B1 (fr) 1999-03-01 2001-05-18 Prographarm Laboratoires Comprime orodispersible presentant une faible friabilite et son procede de preparation
KR20010006835A (ko) * 1999-03-25 2001-01-26 김선진 경구용 속붕해정
US6740339B1 (en) 1999-06-18 2004-05-25 Takeda Chemical Industries, Ltd. Quickly disintegrating solid preparations
JP2001058944A (ja) * 1999-06-18 2001-03-06 Takeda Chem Ind Ltd 速崩壊性固形製剤
HK1047701A1 (en) * 1999-10-13 2003-03-07 Kyowa Hakko Kogyo Co., Ltd. Compression molded product and production method therefor
CN100342846C (zh) * 1999-10-13 2007-10-17 协和发酵工业株式会社 压缩成形品及其制备方法
WO2001052820A1 (en) * 2000-01-17 2001-07-26 Kyowa Hakko Kogyo Co., Ltd. Bubbling tablet, bubbling bath additive tablet, bubbling washing detergent tablet, bubbling tablet for oral administration, and processes for producing these
WO2001072285A1 (en) * 2000-03-27 2001-10-04 Kyowa Hakko Kogyo Co., Ltd. Easy-to-take granule
US6316029B1 (en) * 2000-05-18 2001-11-13 Flak Pharma International, Ltd. Rapidly disintegrating solid oral dosage form
JP4840549B2 (ja) * 2000-11-20 2011-12-21 トーアエイヨー株式会社 安定な血管拡張剤及びその製造方法
EP1226818A1 (de) * 2001-01-26 2002-07-31 Pfizer Products Inc. Arzneiform mit verbesserten kohäsiven und kompressiven Eigenschaften
CA2440365A1 (en) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co., Ltd. Use of a spray-dried powder comprising a sugar alcohol
CN1494419A (zh) * 2001-03-06 2004-05-05 协和发酵工业株式会社 口腔内快速崩解制剂
CA2439873A1 (en) * 2001-03-06 2002-09-12 Kyowa Hakko Kogyo Co., Ltd. Intraorally rapidly desintegrable tablet
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
CN100490798C (zh) * 2001-11-13 2009-05-27 协和发酵麒麟株式会社 含有l-谷氨酰胺和薁磺酸钠的速崩片剂或口腔内崩解片剂及其制造方法
JP2003238393A (ja) * 2002-02-15 2003-08-27 Otsuka Pharmaceut Co Ltd 施錠性が改善された錠剤及びその製造方法
EP1488811A1 (de) * 2002-03-06 2004-12-22 Kyowa Hakko Kogyo Co., Ltd. Tabletten mit schneller auflösung in der mundhöhle
TWI286942B (en) * 2002-06-10 2007-09-21 Dainippon Sumitomo Pharma Co Rapidly disintegrating tablet and preparing method thereof
EP2283864A1 (de) * 2002-07-16 2011-02-16 Elan Pharma International Ltd. Flüssige Zusammensetzung enthaltend stabilisierte Wirkstoff-Nanopartikeln
FR2845914B1 (fr) * 2002-10-18 2005-11-04 Schwarz Pharma Lab Compose antiemetique a desagregation rapide
DE10248652A1 (de) * 2002-10-18 2004-04-29 Solvay Interox Gmbh Verfahren zur Herstellung von staubfreien Erdalkaliperoxiden
FI20022007A0 (fi) 2002-11-08 2002-11-08 Juvantia Pharma Ltd Oy Oromukosaalinen valmiste ja menetelmä sen valmistamiseksi
GB0226076D0 (en) 2002-11-08 2002-12-18 Rp Scherer Technologies Inc Improved formulations containing substituted imidazole derivatives
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
JP4551627B2 (ja) * 2003-02-28 2010-09-29 東和薬品株式会社 口腔内崩壊錠剤の製造方法
JP5584509B2 (ja) * 2003-02-28 2014-09-03 東和薬品株式会社 口腔内崩壊錠剤
GB2404662A (en) * 2003-08-01 2005-02-09 Reckitt Benckiser Cleaning composition
US8545881B2 (en) 2004-04-19 2013-10-01 Eurand Pharmaceuticals, Ltd. Orally disintegrating tablets and methods of manufacture
US10258576B2 (en) 2004-05-24 2019-04-16 Takeda As Particulate comprising a calcium-containing compound and a sugar alcohol
ES2624585T3 (es) * 2004-05-28 2017-07-17 Imaginot Pty Ltd. Sistema de suministro de compuesto terapéutico oral
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
JP4996458B2 (ja) 2004-06-01 2012-08-08 ニコメド ファーマ エイエス 活性物質としてカルシウム含有化合物を含み、咀嚼し、舐め、飲み込むことのできる錠剤
US8747895B2 (en) 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
AU2005299490C1 (en) 2004-10-21 2012-01-19 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
JP4980228B2 (ja) * 2004-10-28 2012-07-18 パンテック・アーゲー 高度に多孔質の急速崩壊性固体剤形および粉末の調製および凍結乾燥工程を含むその製造方法
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
US8846088B2 (en) 2005-02-03 2014-09-30 Takeda Nycomed As Melt granulation of a composition containing a calcium-containing compound
EA013867B1 (ru) 2005-02-03 2010-08-30 Никомед Фарма Ас Способ получения гранулята, содержащего карбонат кальция
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
CA2629904C (en) * 2005-11-28 2018-07-10 Imaginot Pty Ltd. Oral therapeutic compound delivery system
CN102872157A (zh) 2005-12-07 2013-01-16 奈科明制药有限公司 预先压实的含钙组合物
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
JP2009520704A (ja) * 2005-12-21 2009-05-28 エーディーディー アドバンスト ドラッグ デリバリー テクノロジーズ リミテッド 水溶性担体を持つコアを含むペレット
FR2898492B1 (fr) * 2006-03-15 2008-06-06 Pierre Fabre Medicament Sa Comprimes orodispersibles de domperidone
JP5535616B2 (ja) * 2006-03-31 2014-07-02 ルビコン リサーチ プライベート リミテッド 口腔内崩壊錠剤のための直接圧縮性複合材
MX2009002166A (es) 2006-08-31 2009-03-12 Eurand Inc Sistema de distribucion de farmacos, que comprenden soluciones solidas de farmacos debilmente basicos.
WO2008079342A2 (en) * 2006-12-21 2008-07-03 Mallinckrodt Inc. Composition of and method for preparing orally disintegrating tablets
BRPI0808889A2 (pt) * 2007-03-13 2014-11-11 Dainippon Sumitomo Pharma Co Comprimido desintegrante oral
EP1977734A1 (de) * 2007-04-03 2008-10-08 Royal College of Surgeons in Ireland Verfahren zur Herstellung schnelllöslicher Tabletten
JP4980144B2 (ja) * 2007-06-05 2012-07-18 日機装株式会社 固型化透析用剤の製造方法
WO2009004440A2 (en) * 2007-06-29 2009-01-08 Orchid Chemicals & Pharmaceuticals Limited Quick dissolve compositions of memantine hydrochloride
JP5537943B2 (ja) 2007-09-27 2014-07-02 田辺三菱製薬株式会社 速崩壊性固形製剤
EP2233129B1 (de) * 2007-12-28 2014-05-07 Sawai Pharmaceutical Co., Ltd. In der mundhöhle zerfallende tablette und verfahren zu ihrer herstellung
CN102196811B (zh) 2008-10-24 2014-03-19 东丽株式会社 含有4,5-环氧基吗啡烷衍生物的稳定片剂
CA2742449C (en) 2008-11-17 2018-04-24 Takeda As Improved dissolution stability of calcium carbonate tablets
CN102988318A (zh) 2008-11-25 2013-03-27 田边三菱制药株式会社 口腔速崩片及其制备方法
TR200903014A1 (tr) * 2009-04-17 2010-11-22 Sanovel İlaç San. Ve Ti̇c. A.Ş. Oral yolla dağılan dimebolin bileşimleri.
EP2482822B1 (de) 2009-10-01 2018-08-01 Adare Pharmaceuticals, Inc. Oral verabreichte corticosteroid-zusammensetzungen
KR20170113709A (ko) 2009-11-09 2017-10-12 가부시키가이샤 니콘 노광 장치, 노광 방법, 노광 장치의 메인터넌스 방법, 노광 장치의 조정 방법, 및 디바이스 제조 방법
NZ600123A (en) 2009-11-30 2015-04-24 Aptalis Pharmatech Inc Compressible-coated pharmaceutical compositions and tablets and methods of manufacture
KR101765357B1 (ko) 2009-12-02 2017-08-04 아데어 파마수티컬스 에스.알.엘. 펙소페나딘 마이크로캡슐 및 그것을 함유하는 조성물
AR079862A1 (es) * 2010-01-08 2012-02-22 Eurand Inc Composicion de topiramato con sabor enmascarado, un comprimido desintegrable oralmente que comprende la misma y metodo de preparacion
US8426461B2 (en) 2011-01-17 2013-04-23 Takeda Pharmaceutical Company Limited Orally dispersible tablet
EP2665465A1 (de) * 2011-01-17 2013-11-27 Takeda Pharmaceutical Company Limited In der mundhöhle dispergierbare tablette
JP6061516B2 (ja) * 2011-07-14 2017-01-18 協和発酵キリン株式会社 ドンペリドン口腔内崩壊錠
JP6061924B2 (ja) 2011-10-14 2017-01-18 武田薬品工業株式会社 口腔内分散性製剤
JP6004882B2 (ja) * 2012-10-15 2016-10-12 三菱商事フードテック株式会社 圧縮成形に用いるためのマンニトール賦形剤及びこれを含有する錠剤
WO2015034678A2 (en) 2013-09-06 2015-03-12 Aptalis Pharmatech, Inc. Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
TWI777515B (zh) 2016-08-18 2022-09-11 美商愛戴爾製藥股份有限公司 治療嗜伊紅性食道炎之方法
JP2022130075A (ja) * 2021-02-25 2022-09-06 フロイント産業株式会社 顆粒及びその製造方法、並びに錠剤

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2246013A1 (de) * 1972-09-20 1974-03-28 Boehringer Mannheim Gmbh Verfahren zur herstellung von poroesen tabletten
IE45770B1 (en) 1976-10-06 1982-11-17 Wyeth John & Brother Ltd Pharmaceutical dosage forms
JPS5614098A (en) * 1979-07-13 1981-02-10 Takeda Chem Ind Ltd Externally lubricating tablet making machine
JPH0653658B2 (ja) 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
JPH0774153B2 (ja) * 1986-04-14 1995-08-09 三共株式会社 ロキソプロフェン・ナトリウム含有製剤
JPS63162619A (ja) * 1986-12-25 1988-07-06 Teisan Seiyaku Kk 遅溶性顆粒及びそれを用いた持続性複合顆粒
KR960011236B1 (ko) * 1987-05-08 1996-08-21 스미스 클라인 앤드 프렌취 라보라토리스 리미티드 제약학적 조성물 및 고체 제형
GB8710965D0 (en) * 1987-05-08 1987-06-10 Smith Kline French Lab Pharmaceutical compositions
EP0349103B1 (de) * 1988-05-04 1992-11-25 Smith Kline & French Laboratories Limited Kautablette
GB8824392D0 (en) * 1988-10-18 1988-11-23 Ciba Geigy Ag Dispersible formulation
HU200926B (en) * 1988-10-28 1990-09-28 Egyt Gyogyszervegyeszeti Gyar Pharmaceutical composition comprising piroxicam and lactose for use in making tablets or capsules
JP2781442B2 (ja) * 1990-02-19 1998-07-30 旭化成工業株式会社 顆粒含有錠剤
ATE172637T1 (de) 1991-12-24 1998-11-15 Yamanouchi Pharma Co Ltd Intrabukkal desintegrierende zubereitung und ihre herstellung
EP0553777B1 (de) * 1992-01-29 2002-04-24 Takeda Chemical Industries, Ltd. Schnellösliche Tablette und ihre Herstellung
DE69331378D1 (de) 1992-02-18 2002-01-31 Nippon Shinyaku Co Ltd Verfahren zur Herstellung von schnelllöslicher Tabletten und schnelllöslichen Tablette beinhaltend Xylitol
GB9224855D0 (en) * 1992-11-27 1993-01-13 Smithkline Beecham Plc Pharmaceutical compositions
CA2258159C (en) * 1996-06-14 2006-03-21 Kyowa Hakko Kogyo Co., Ltd. Intraorally rapidly disintegrable tablet

Also Published As

Publication number Publication date
ATE477793T1 (de) 2010-09-15
JP3797387B2 (ja) 2006-07-19
EP0914818B1 (de) 2005-06-08
EP0914818A1 (de) 1999-05-12
PT914818E (pt) 2005-08-31
EA001898B1 (ru) 2001-10-22
DE69739967D1 (de) 2010-09-30
AU733032B2 (en) 2001-05-03
EA199900028A1 (ru) 1999-06-24
JP2012167105A (ja) 2012-09-06
AU3189597A (en) 1998-01-07
JP5484514B2 (ja) 2014-05-07
CA2258159C (en) 2006-03-21
CN1154479C (zh) 2004-06-23
WO1997047287A1 (en) 1997-12-18
EP1598061B1 (de) 2010-08-18
DE69733476T2 (de) 2006-03-23
AU733032C (en) 2002-01-03
CA2258159A1 (en) 1997-12-18
ATE297191T1 (de) 2005-06-15
CN1224349A (zh) 1999-07-28
EP0914818A4 (de) 2001-03-14
EP1598061A1 (de) 2005-11-23
JP2006077018A (ja) 2006-03-23
US20010014340A1 (en) 2001-08-16
JP2009256372A (ja) 2009-11-05
DE69733476D1 (de) 2005-07-14
ES2243998T3 (es) 2005-12-01

Similar Documents

Publication Publication Date Title
PT914818E (pt) Comprimido de desintegracao rapida por via intraoral
ES2192226T3 (es) Composicion farmaceutica oral que contiene agentes activos antimicrobianos y pantoprazol de liberacion prolongada.
CA2102630A1 (en) Pharmaceutical compositions of compacted medicaments
GR3035308T3 (en) Bioadhesive pharmaceutical composition for controlled release of drugs.
CA2085466A1 (en) Intermittent threaded dental posts
DE69006385D1 (de) Pharmazeutische Formulierung.
CA2170647A1 (en) Multiple unit tableted dosage form i
CA2186039A1 (en) New oral pharmaceutical dosage form
AU651894B2 (en) Matrix tablet permitting the sustained release of indapamide after oral administration
CA2282513A1 (en) Stabilization of acid sensitive benzimidazoles with amino acid/cyclodextrin combinations
CA2093282A1 (en) Intraoral medicament-releasing device
DE60232496D1 (de) Tabletten, die in der mundhöhle schnell zerfallen
CA2283408A1 (en) Swallow tablet comprising paracetamol
FI863435A0 (fi) Smakdoeljande kompositioner.
KR960702322A (ko) 활성성분으로서의 디클로로메틸렌디포스폰산을 함유하며 약효가 개선된 정제 (more easily biologically absorbed tablet containing dichloromethylene diphosphonic acid as the active agent)
ATE87468T1 (de) Antacidatabletten.
HUP9901021A2 (hu) Famciklovirt nagy koncentrációban tartalmazó gyógyászati tabletták
ITMI950180A0 (it) Procedimento per l'ottenimento di gomme da masticare medicate dotate di gusto gradevole indipendentemente dal principio attivo incorporato e compresse di gomma da masticare cosi' ottenute
IT8821437A0 (it) Procedimento per prolungare la permanenza nel tratto gastrointestinale di farmaci in formulazioni ad effetto prolungato e forme di dosaggio cosi' ottenute.
ITBO930460A0 (it) Procedimento per preparare forme farmaceutiche a rilascio controllato del principio attivo e le forme farmaceutiche cosi' ottenute.
ITMI913248A1 (it) Composizioni terapeutiche adatte per la somministrazione orale contenenti come principio attivo uno o piu' tioesteri del glutatione e procedimento per la preparazione dei suddetti principi attivi