DK0921785T3 - Kombination af syreproteaseenzymer og sure puffere og anvendelser deraf - Google Patents

Kombination af syreproteaseenzymer og sure puffere og anvendelser deraf

Info

Publication number
DK0921785T3
DK0921785T3 DK97930044T DK97930044T DK0921785T3 DK 0921785 T3 DK0921785 T3 DK 0921785T3 DK 97930044 T DK97930044 T DK 97930044T DK 97930044 T DK97930044 T DK 97930044T DK 0921785 T3 DK0921785 T3 DK 0921785T3
Authority
DK
Denmark
Prior art keywords
combination
acid protease
protease enzymes
acidic buffers
acid
Prior art date
Application number
DK97930044T
Other languages
Danish (da)
English (en)
Inventor
Glen Gillis
Michael Bishop
Scott J Norton
Original Assignee
Active Organics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Active Organics Inc filed Critical Active Organics Inc
Application granted granted Critical
Publication of DK0921785T3 publication Critical patent/DK0921785T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/488—Aspartic endopeptidases (3.4.23), e.g. pepsin, chymosin, renin, cathepsin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/006—Antidandruff preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
DK97930044T 1996-06-13 1997-06-13 Kombination af syreproteaseenzymer og sure puffere og anvendelser deraf DK0921785T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/664,056 US5976556A (en) 1996-06-13 1996-06-13 Combination of acid protease enzymes and acidic buffers and uses thereof
EP97930044A EP0921785B1 (de) 1996-06-13 1997-06-13 Kombination von saurer protease-enzyme und saure puffers und ihre verwendung
PCT/US1997/010427 WO1997047283A1 (en) 1996-06-13 1997-06-13 Combination of acid protease enzymes and acidic buffers and uses thereof

Publications (1)

Publication Number Publication Date
DK0921785T3 true DK0921785T3 (da) 2005-04-18

Family

ID=24664334

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97930044T DK0921785T3 (da) 1996-06-13 1997-06-13 Kombination af syreproteaseenzymer og sure puffere og anvendelser deraf

Country Status (11)

Country Link
US (2) US5976556A (de)
EP (2) EP0921785B1 (de)
JP (2) JP4681087B2 (de)
KR (1) KR20000016635A (de)
AT (2) ATE552891T1 (de)
AU (1) AU3396597A (de)
DE (1) DE69731955T2 (de)
DK (1) DK0921785T3 (de)
ES (2) ES2383682T3 (de)
PT (1) PT921785E (de)
WO (1) WO1997047283A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5976556A (en) * 1996-06-13 1999-11-02 Active Organics, Inc. Combination of acid protease enzymes and acidic buffers and uses thereof
WO1998048775A1 (en) * 1997-02-12 1998-11-05 Johnson & Johnson Consumer Companies, Inc. Serine protease and topical retinoid compositions
FR2761363B1 (fr) * 1997-03-28 1999-11-26 Oreal Polypeptide purifie de l'epiderme et son utilisation
CA2317582C (en) * 1998-01-06 2009-03-31 Nicholas A. Sceusa A drug dosage form based on the teorell-meyer gradient
US6210693B1 (en) * 1998-02-10 2001-04-03 Shiseido Company, Ltd. Oil-in-water type emulsified composition
FR2777185B1 (fr) * 1998-04-08 2001-03-16 Serobiologiques Lab Sa Composition cosmetique et/ou pharmaceutique pour le traitement des rides et procede de traitement mettant en oeuvre cette composition
US6656701B2 (en) * 1999-07-16 2003-12-02 Actim Organics, Inc Combination of acid protease enzymes and acidic buffers and uses thereof
US6416769B1 (en) * 2000-03-03 2002-07-09 Australian Importers, Ltd. Cosmetic compositions comprising exfoliating enzymes and uses thereof
DE10042576B4 (de) * 2000-08-15 2004-08-12 Coty B.V. Kosmetischer Basiskomplex und dessen Verwendung
JP2002284665A (ja) * 2001-03-23 2002-10-03 Nippon Hypox Lab Inc 化粧料
US7364565B2 (en) * 2001-07-27 2008-04-29 Ramot At Tel Aviv University Ltd. Controlled enzymatic removal and retrieval of cells
US20030021775A1 (en) * 2001-07-27 2003-01-30 Ramot University Authority For Applied Research & Industrial Development Ltd. Device for and method of controlled enzymatic removal and retrieval of tissue
US6835385B2 (en) * 2002-06-14 2004-12-28 Carol J. Buck Compositions and methods for softening, thinning and removing hyperkeratotic tissue
US6858215B2 (en) * 2002-06-14 2005-02-22 Carol J. Buck Compositions and methods for softening, thinning and removing hyperkeratotic tissue
AU2003201853A1 (en) * 2002-07-02 2004-01-23 Noevir Co., Ltd. Skin preparations for external use
AU2003263906B2 (en) * 2002-08-23 2009-10-29 Peter K. Law Biologic skin repair and enhancement
AU2004280233A1 (en) * 2003-10-09 2005-04-21 Arbios Technology, Inc. Non-invasive system for detecting skin cancer
US20070244195A1 (en) * 2004-05-18 2007-10-18 Burkhart Craig N Treatment methods with peroxides and tertiary amines
JP2008522625A (ja) * 2004-12-09 2008-07-03 ダウ グローバル テクノロジーズ インコーポレイティド 酵素安定化
US8278359B2 (en) 2005-02-25 2012-10-02 Johnson & Johnson Consumer Companies, Inc. Compositions containing amines and use thereof to treat acne or reduce the appearance of oil or pores on the skin
US20070027152A1 (en) * 2005-07-27 2007-02-01 Clark Kathleen L Topical anti-pruritic compositions and methods of action of same
JP2007145931A (ja) * 2005-11-25 2007-06-14 Ecobio 動物用耳穴洗浄剤
US7776339B2 (en) 2006-01-11 2010-08-17 Active Organics, Lp Extract of R. miehei
US20070264222A1 (en) * 2006-05-10 2007-11-15 Biohealth Advance, Llc Enhanced protection against skin injury in humans
FR2909554B1 (fr) * 2006-12-08 2013-11-01 Biorecept Lab Composition cosmetique anti-rides comprenant de l'acide hyaluronique
US7381433B1 (en) 2007-01-08 2008-06-03 Johnson & Johnson Consumer Companies, Inc. Compositions containing an extract of a primula denticulata and use thereof
EP2011471A1 (de) * 2007-07-02 2009-01-07 Johnson & Johnson Consumer France SAS Schäumende Ölzubereitungen
US7854936B2 (en) * 2008-01-14 2010-12-21 Active Organics, Inc. Anti-inflammatory hydrolysate of C. versicolor
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
EP2662090A1 (de) 2008-04-14 2013-11-13 Halozyme, Inc. Modifizierte Hyaluronidasen und ihre Verwendungen bei der Behandlung von Erkrankungen und Zuständen im Zusammenhang mit Hyaluronan
FR2930727B1 (fr) * 2008-04-30 2012-10-05 Evolution Dermatologique Lab Composition pour le traitement des etats seborrheiques.
ITTO20080579A1 (it) * 2008-07-28 2010-01-29 Chiara Cesano Composizione per la rigenerazione di tessuto ipertrofico, relativi prodotti ed usi
US20110229451A2 (en) * 2009-03-06 2011-09-22 Halozyme, Inc. Temperature sensitive mutants of matrix metalloproteases and uses thereof
RU2012105529A (ru) * 2009-07-17 2013-08-27 Колопласт А/С Адгезивный пластырь с ферментом
EP2316438A1 (de) 2009-10-30 2011-05-04 Johnson & Johnson GmbH Band, insbesondere Klebeband zur Behandlung von Hauterkrankungen mit mindestens einem Hyperkeratosehemmer und/oder mindestens einem keratinolytischem Wirkstoff
EP2316436A1 (de) 2009-10-30 2011-05-04 Johnson & Johnson GmbH Band, insbesondere Klebeband zur Behandlung von Hauterkrankungen mit mindestens einem Film, insbesondere einem löslichen Film, mit mindestens einem Enzym
US20110152384A1 (en) * 2009-12-17 2011-06-23 Gunn Euen T Mild leave-on skin care compositions
EP2340803A1 (de) * 2009-12-30 2011-07-06 Brands Asia Pacific Limited Zusammensetzung zum Entfernen abgestorbener Hautzellen und Pad für Hände und Füße enthaltend besagte Zusammensetzung
WO2012095702A1 (en) * 2011-01-13 2012-07-19 Medestea Internazionale S.P.A. A composition for the regeneration of atrophic tissues
WO2012154903A1 (en) 2011-05-10 2012-11-15 Active Organics, Inc. Compositions containing extracts of mucor miehei and mucor rouxii
FR2984725B1 (fr) * 2011-12-26 2014-01-31 Achaladanelle Utilisation d'une composition cosmetique ou dermocosmetique pour lutter contre les effets du tabac sur la peau
US20150196625A9 (en) 2013-01-07 2015-07-16 Rudolph D. Paladini Metal Sensitive Mutants of Matrix Metalloproteases and uses thereof
KR101531479B1 (ko) * 2014-11-21 2015-06-26 세원셀론텍(주) 의료용 재료로 사용하기 위한 고농도 콜라겐 제조방법
JP6891118B2 (ja) 2014-12-23 2021-06-18 インテレクチュアル プロパティ アソシエイツ エルエルシーIntellectual Property Associates, LLC 経皮投与のための方法及び製剤
KR102078140B1 (ko) * 2015-03-13 2020-02-17 주식회사 엘지생활건강 pH 완충 시스템을 갖는 유화 화장료 조성물
KR101865764B1 (ko) * 2017-01-13 2018-06-11 주식회사 아미코스메틱 천연 복합 추출물 및 미세침 분말을 유효성분으로 포함하는 각질 박리용 화장료 조성물
US20190083386A1 (en) 2017-09-15 2019-03-21 Ampersand Biopharmaceuticals, Inc. Methods and formulations for transdermal administration of buffering agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU439288A1 (ru) * 1971-07-29 1974-08-15 Республиканский Ожоговый Центр При Грьковском Научно-Исследовательском Институте Травматологии И Ортопедии Средство дл растворени некротизированных тканей
US4021572A (en) * 1975-07-23 1977-05-03 Scott Eugene J Van Prophylactic and therapeutic treatment of acne vulgaris utilizing lactamides and quaternary ammonium lactates
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
JPS60215621A (ja) * 1984-04-12 1985-10-29 Kao Corp 弱酸性入浴剤
US5431913A (en) * 1992-01-24 1995-07-11 Phillips; Eva J. Skin cleansing and exfoliant composition and method of treating skin
DK72593D0 (da) * 1993-06-18 1993-06-18 Symbicom Ab Rekombinant protein
GB9319104D0 (en) * 1993-09-15 1993-11-03 Unilever Plc Skin care method & composition
US5516517A (en) * 1994-05-02 1996-05-14 Exfoliation Cleansing Hydration Oxygenation Corporation Method for nutritional oxygenation of the skin
US5976556A (en) * 1996-06-13 1999-11-02 Active Organics, Inc. Combination of acid protease enzymes and acidic buffers and uses thereof

Also Published As

Publication number Publication date
KR20000016635A (ko) 2000-03-25
US5976556A (en) 1999-11-02
EP0921785A1 (de) 1999-06-16
EP0921785A4 (de) 2002-02-13
JP2000512298A (ja) 2000-09-19
ES2235239T3 (es) 2005-07-01
PT921785E (pt) 2005-05-31
ATE552891T1 (de) 2012-04-15
JP2007302680A (ja) 2007-11-22
WO1997047283A1 (en) 1997-12-18
US6569437B1 (en) 2003-05-27
EP1598057B1 (de) 2012-04-11
JP4681087B2 (ja) 2011-05-11
EP1598057A1 (de) 2005-11-23
DE69731955D1 (de) 2005-01-20
AU3396597A (en) 1998-01-07
EP0921785B1 (de) 2004-12-15
DE69731955T2 (de) 2005-12-22
ATE284670T1 (de) 2005-01-15
ES2383682T3 (es) 2012-06-25

Similar Documents

Publication Publication Date Title
AU3396597A (en) Combination of acid protease enzymes and acidic buffers and uses thereof
IL149459A0 (en) Recombinant gelatins
BR9710993A (pt) Derivados anticonvulsivos úteis no tratamento de esclerose lateral amiotrófica (als)
BR9811099A (pt) Inibidores de urocinase
TR199600516A2 (tr) Kakaonun enzimatik muamelesi.
DK0760848T3 (da) Lactobacillusstammer af menneskelig oprindelse, deres sammensætninger og anvendelse deraf
ATE335813T1 (de) Protease varianten
BR9710994A (pt) Derivados anticonvulsivos úteis no tratamento de obesidade.
EP1007556A4 (de) Troponin untereinheiten und fragmente zur verwendung als inhibitoren der angiogenese
NO941937D0 (no) Sakarinderivater som inhiberer proteolytiske enzymer
ATE331037T1 (de) Isoliertes frpb nukleinsäuremolekül und entsprechende impfstoff
DE69720335D1 (de) Recombinante Fructosyl-Aminosäure-Oxidase
EP0471756A4 (en) Saccharin derivatives useful as proteolytic enzyme inhibitors and preparation thereof
BR9907655A (pt) Derivados de ácido di-hidróxi-hexanóico
PT1119359E (pt) Formulacao de 2-metil-tieno-benzodiazepina
DK0840792T3 (da) (S)-hydroxynitrillyase fra Hevea brasiliensis
DK0977871T3 (da) Neurotrypsin
BR9714376A (pt) Antagonistas de somatostatina
DK0942992T3 (da) O-fucosyltransferase
AU7028798A (en) Use of 2-methylthiazolidine-2,4-dicarboxylic acid as mucolytic agent
BG103859A (en) The use of 1-ar(alk)yl-imidazolin-2-on for the treatment of fear and stress conditions
ATE281522T1 (de) Sentrin-spezifische menschliche protease senp1
DK0647654T3 (da) Anomere fluor-ribosylaminer
AU2253197A (en) Novel substituted N-Methyl-N-(4-(4-(1H-benzimidazol- 2-yl){1,4}diazepan-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
BR9710992A (pt) Derivados anticovulsivos úteis no tratamento de psorìase