BR9714376A - Antagonistas de somatostatina - Google Patents

Antagonistas de somatostatina

Info

Publication number
BR9714376A
BR9714376A BR9714376A BR9714376A BR9714376A BR 9714376 A BR9714376 A BR 9714376A BR 9714376 A BR9714376 A BR 9714376A BR 9714376 A BR9714376 A BR 9714376A BR 9714376 A BR9714376 A BR 9714376A
Authority
BR
Brazil
Prior art keywords
somatostatin antagonists
somatostatin
antagonists
residue
aspects
Prior art date
Application number
BR9714376A
Other languages
English (en)
Inventor
Barry Morgn
William Murphy
David H Coy
Original Assignee
Sod Conseils Rech Applic
Admin Tulane Education Fund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/855,204 external-priority patent/US6262229B1/en
Application filed by Sod Conseils Rech Applic, Admin Tulane Education Fund filed Critical Sod Conseils Rech Applic
Publication of BR9714376A publication Critical patent/BR9714376A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção: <B>"ANTAGONISTAS DE SOMATOSTATINA"<D>. Os aspectos da invenção antagonistas de somatostatina tendo um aminoácido D no segundo resíduo.
BR9714376A 1996-12-04 1997-12-04 Antagonistas de somatostatina BR9714376A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3235896P 1996-12-04 1996-12-04
US76067296A 1996-12-04 1996-12-04
US08/855,204 US6262229B1 (en) 1996-12-04 1997-05-13 Somatostatin antagonists
PCT/US1997/022251 WO1998024807A2 (en) 1996-12-04 1997-12-04 Somatostatin antagonists

Publications (1)

Publication Number Publication Date
BR9714376A true BR9714376A (pt) 2000-03-21

Family

ID=27364103

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9714376A BR9714376A (pt) 1996-12-04 1997-12-04 Antagonistas de somatostatina

Country Status (17)

Country Link
EP (1) EP0956296B1 (pt)
JP (2) JP4124820B2 (pt)
KR (1) KR100479149B1 (pt)
AT (1) ATE330966T1 (pt)
AU (1) AU728224B2 (pt)
BR (1) BR9714376A (pt)
CA (1) CA2274144C (pt)
DE (1) DE69736193T2 (pt)
ES (1) ES2264174T3 (pt)
HU (1) HUP0003396A3 (pt)
IL (1) IL130166A0 (pt)
MX (1) MXPA99004944A (pt)
NZ (1) NZ335879A (pt)
PL (1) PL334089A1 (pt)
RU (1) RU2179172C2 (pt)
TW (1) TW575582B (pt)
WO (1) WO1998024807A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1367793A (zh) * 1999-06-04 2002-09-04 研究及应用科学协会股份有限公司 神经调节肽b和生长抑素受体拮抗剂
US6864234B1 (en) 1999-06-25 2005-03-08 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Somatostatin agonists
CN1367792A (zh) * 1999-06-25 2002-09-04 研究及应用科学协会股份有限公司 促生长素抑制素激动剂
DK1372688T3 (da) * 2001-03-08 2008-08-25 Univ Tulane Somatostatin-antagonister
CN1541102A (zh) * 2001-04-09 2004-10-27 生长激素抑制素激动剂
KR100795425B1 (ko) * 2003-04-11 2008-01-17 소시에떼 더 콘세이유 더 레세르세 에 다플리까띠옹 시엔띠피끄, 에스.아.에스. 소마토스타틴-도파민 키메라 유사체
ES2410207T3 (es) * 2006-10-16 2013-07-01 The Salk Institute For Biological Studies Antagonistas de la somatostatina selectivos para receptor(SSTR2)
US8691761B2 (en) 2006-10-16 2014-04-08 Jean E. F. Rivier Somatostatin receptor 2 antagonists
ES2351569B8 (es) * 2009-05-07 2012-06-20 Bcn Peptides S.A. Ligandos peptídicos de receptores de somatostatina.
WO2011151782A1 (en) 2010-06-02 2011-12-08 Preglem Sa A role for somatostatin to modulate initiation of follicular growth in the human ovary
EP2399931A1 (fr) * 2010-06-22 2011-12-28 Ipsen Pharma S.A.S. Nouveaux composés octapeptidiques et leur utilisation thérapeutique

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917581A (en) * 1974-08-01 1975-11-04 Ayerst Mckenna & Harrison Derivatives of somatostatin and process therefor
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
US4904642A (en) * 1985-09-12 1990-02-27 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US4853371A (en) * 1986-06-17 1989-08-01 The Administrators Of The Tulane Educational Fund Therapeutic somatostatin analogs
US5073541A (en) * 1987-11-18 1991-12-17 Administrators Of The Tulane Educational Fund Treatment of small cell lung cancer with somatostatin analogs
CA2053250A1 (en) * 1989-04-26 1990-10-27 David H. Coy Linear somatostatin analogs
US5633263A (en) * 1989-04-26 1997-05-27 The Administrators Of The Tulane Educational Fund Linear somatostatin analogs
US5708135A (en) * 1995-09-29 1998-01-13 Biomeasure Incorporated Cyclic peptide analogs of somatostatin

Also Published As

Publication number Publication date
IL130166A0 (en) 2000-06-01
EP0956296A2 (en) 1999-11-17
TW575582B (en) 2004-02-11
ES2264174T3 (es) 2006-12-16
DE69736193D1 (de) 2006-08-03
AU728224B2 (en) 2001-01-04
PL334089A1 (en) 2000-01-31
KR20000069243A (ko) 2000-11-25
HUP0003396A1 (hu) 2001-02-28
CA2274144C (en) 2004-03-30
HUP0003396A3 (en) 2001-03-28
WO1998024807A3 (en) 1998-10-15
JP2001505580A (ja) 2001-04-24
KR100479149B1 (ko) 2005-03-25
JP4124820B2 (ja) 2008-07-23
AU7624898A (en) 1998-06-29
ATE330966T1 (de) 2006-07-15
DE69736193T2 (de) 2007-05-03
JP4264762B2 (ja) 2009-05-20
MXPA99004944A (es) 2004-09-10
CA2274144A1 (en) 1998-06-11
WO1998024807A2 (en) 1998-06-11
EP0956296B1 (en) 2006-06-21
JP2008120818A (ja) 2008-05-29
NZ335879A (en) 2000-11-24
RU2179172C2 (ru) 2002-02-10

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]