DK0922054T3 - Antikoagulerende peptidylargininaldehydderivater - Google Patents

Antikoagulerende peptidylargininaldehydderivater

Info

Publication number: DK0922054T3
Authority: DK; Denmark
Prior art keywords: group; peptidylargininaldehyde; anticoagulant; derivatives; alanyl
Prior art date: 1996-06-05

Application number

DK97925210T

Other languages

Danish (da)

English (en)

Inventor

Sandor Bajusz

Attila Juhasz

Eva Barabas

Andras Feher

Gabriella Szabo

Erzsebet Szell

Iren Veghelyi

Emilia Lavich

Eva Kaszas

Juzsef Lango

Imre Moravcsik

Agnes Szeker

Zsuzsanna Taschler

Gabor Toth

Zsuzsanna Mohai

Anna Maria Szalkay

Klara Makk

Original Assignee

Gyogyszerkutato Intezet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-05

Filing date

1997-06-05

Publication date

2002-12-09

1997-06-05 Application filed by Gyogyszerkutato Intezet filed Critical Gyogyszerkutato Intezet

2002-12-09 Application granted granted Critical

2002-12-09 Publication of DK0922054T3 publication Critical patent/DK0922054T3/da

Links

239000003146 anticoagulant agent Substances 0.000 title 1
229940127219 anticoagulant drug Drugs 0.000 title 1
125000000174 L-prolyl group Chemical group [H]N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(*)=O 0.000 abstract 2
-1 3-cyclopentyl-D-alanyl group Chemical group 0.000 abstract 1
239000004475 Arginine Substances 0.000 abstract 1
125000002059 L-arginyl group Chemical group O=C([*])[C@](N([H])[H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])C(=N[H])N([H])[H] 0.000 abstract 1
208000007536 Thrombosis Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
230000023555 blood coagulation Effects 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000002265 prevention Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Hematology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK97925210T 1996-06-05 1997-06-05 Antikoagulerende peptidylargininaldehydderivater DK0922054T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
HU9601526A HU224315B1 (hu)	1996-06-05	1996-06-05	Véralvadásgátló hatású peptidil-arginin-aldehid-származékok és a vegyületeket tartalmazó gyógyszerkészítmények
PCT/HU1997/000028 WO1997046576A1 (en)	1996-06-05	1997-06-05	Anticoagulant peptidyl-arginine aldehyde derivatives

Publications (1)

Publication Number	Publication Date
DK0922054T3 true DK0922054T3 (da)	2002-12-09

Family

ID=89994025

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97925210T DK0922054T3 (da)	1996-06-05	1997-06-05	Antikoagulerende peptidylargininaldehydderivater

Country Status (12)

Country	Link
US (1)	US6235707B1 (de)
EP (1)	EP0922054B1 (de)
JP (1)	JP3970935B2 (de)
AT (1)	ATE222261T1 (de)
AU (1)	AU726516B2 (de)
CA (1)	CA2256391C (de)
DE (1)	DE69714745T2 (de)
DK (1)	DK0922054T3 (de)
ES (1)	ES2182086T3 (de)
HU (1)	HU224315B1 (de)
PT (1)	PT922054E (de)
WO (1)	WO1997046576A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2002506024A (ja) *	1998-03-13	2002-02-26	メルクエンドカムパニーインコーポレーテッド	急性冠動脈虚血症候群および関連状態に対する併用療法および組成物
US6136804A (en)	1998-03-13	2000-10-24	Merck & Co., Inc.	Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
PL343424A1 (en)	1998-04-10	2001-08-13	Japan Tobacco Inc	Amidine compounds
US7030141B2 (en)	2001-11-29	2006-04-18	Christopher Franklin Bigge	Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
JP4373792B2 (ja)	2002-02-11	2009-11-25	ゴールド−ティーテックインコーポレイテッド	血栓形成を予防する方法
AU2003302238A1 (en)	2002-12-03	2004-06-23	Axys Pharmaceuticals, Inc.	2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
KR100874091B1 (ko) *	2007-08-16	2008-12-16	조정용	공기점토 및 이의 제조방법
EP2306178A1 (de)	2009-09-30	2011-04-06	Roche Diagnostics GmbH	Verfahren zum Steuern einer photometrischen Messeinheit eines Messgeräts zur Gewinnung und Untersuchung einer Körperflüssigkeitsprobe sowie Messsystem
EP2471945A1 (de) *	2010-12-30	2012-07-04	Siemens Healthcare Diagnostics Products GmbH	Verfahren zur Bestimmung von Inhibitoren der Gerinnung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1161431A (en) *	1979-05-11	1984-01-31	Lars G. Svendsen	Tripeptide derivatives
HU192646B (en) *	1984-12-21	1987-06-29	Gyogyszerkutato Intezet	Process for preparing new n-alkyl-peptide aldehydes
IL99527A (en) *	1990-09-28	1997-08-14	Lilly Co Eli	Tripeptide antithrombotic agents

1996
- 1996-06-05 HU HU9601526A patent/HU224315B1/hu not_active IP Right Cessation
1997
- 1997-06-05 WO PCT/HU1997/000028 patent/WO1997046576A1/en not_active Ceased
- 1997-06-05 US US09/194,124 patent/US6235707B1/en not_active Expired - Fee Related
- 1997-06-05 DE DE69714745T patent/DE69714745T2/de not_active Expired - Fee Related
- 1997-06-05 EP EP97925210A patent/EP0922054B1/de not_active Expired - Lifetime
- 1997-06-05 CA CA002256391A patent/CA2256391C/en not_active Expired - Fee Related
- 1997-06-05 DK DK97925210T patent/DK0922054T3/da active
- 1997-06-05 ES ES97925210T patent/ES2182086T3/es not_active Expired - Lifetime
- 1997-06-05 AU AU30436/97A patent/AU726516B2/en not_active Ceased
- 1997-06-05 PT PT97925210T patent/PT922054E/pt unknown
- 1997-06-05 AT AT97925210T patent/ATE222261T1/de not_active IP Right Cessation
- 1997-06-05 JP JP50035298A patent/JP3970935B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
JP3970935B2 (ja)	2007-09-05
AU3043697A (en)	1998-01-05
EP0922054B1 (de)	2002-08-14
HU224315B1 (hu)	2005-07-28
US6235707B1 (en)	2001-05-22
HUP9601526A3 (en)	1999-03-01
HU9601526D0 (en)	1996-08-28
DE69714745T2 (de)	2003-04-24
HUP9601526A2 (hu)	1998-10-28
AU726516B2 (en)	2000-11-09
JP2000512278A (ja)	2000-09-19
ES2182086T3 (es)	2003-03-01
CA2256391C (en)	2009-11-24
ATE222261T1 (de)	2002-08-15
EP0922054A1 (de)	1999-06-16
CA2256391A1 (en)	1997-12-11
PT922054E (pt)	2002-12-31
WO1997046576A1 (en)	1997-12-11
DE69714745D1 (de)	2002-09-19

Similar Documents

Publication	Publication Date	Title
FR16C1001I1 (fr)	2016-07-01	"Dérivé de 2-oxo-1-pyrrolidine et ses applications pharmaceutique"
EA200000592A1 (ru)	2000-12-25	Азаполициклические соединения, конденсированные с арилом
TR200003478T2 (tr)	2001-03-21	Antikanser maddeleri olarak faydalı izotiyazol türevleri
EA200400149A1 (ru)	2004-10-28	Бензотиепины, обладающие активностью ингибиторов перемещения желчных кислот в подвздошной кишке и поглощения таурохолата
BR9811099A (pt)	2002-05-14	Inibidores de urocinase
DK0889876T3 (da)	2001-09-24	Meta-substituerede phenylensulfonamidderivater
EA199901016A1 (ru)	2000-06-26	9-оксим-производные эритромицина
DE69716810D1 (de)	2002-12-12	2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
EA200100983A1 (ru)	2002-10-31	Производные 13-метилэритромицина
EA200200479A1 (ru)	2002-10-31	Новые олигосахариды, их получение и содержащие их фармацевтические композиции
FR2741619B1 (fr)	1998-02-13	Nouveaux derives de 2,3,5-trimethyl-4-hydroxy-anilides, leur preparation et leur application en therapeutique
KR950014067A (ko)	1995-06-15	아릴아미드유도체
DK0922054T3 (da)	2002-12-09	Antikoagulerende peptidylargininaldehydderivater
ES2180564T3 (es)	2003-02-16	2-fenil-3-azoilbenzotiofenos para aumentar la expresion de trombomodulina.
MD1560F2 (en)	2000-11-30	Cyclic compounds, pharmaceutical compositions on base thereof and methods of treatment of infections or diseases provoked by retroviruses.
DK0488513T3 (da)	1996-06-17	Anvendelse af dioxabicyclo(3.3.0)octanderivater til fremstilling af et medikament til inhibering af cholesterolmetabolismen
BR9506552A (pt)	1997-10-28	Método de inibição de integrase retroviral
DK0736029T3 (da)	2006-05-15	Antikonvulsive pseudofructopyranosesulfamater
DK0412940T3 (da)	1997-07-14	Hydantoin eller imidazolidintrionderivater til forebyggelse eller behandling af nyresvigt.
MD502G2 (ro)	1996-11-30	Derivaţi noi ai adenozinei, procedee de preparare a lor, compoziţii farmaceutice ce le conţin
FR2669030B1 (fr)	1992-12-31	Nouveaux derives d'imidazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
EA200200292A1 (ru)	2002-10-31	Производные гигромицина
EA199700302A1 (ru)	1998-04-30	Биологически активные уреидо-производные, полезные при лечении рассеянного склероза
EA200100444A1 (ru)	2001-10-22	Производные гигромицина а в качестве антибактериальных агентов
DE69528984D1 (de)	2003-01-09	Hemmung der leukotrienbiosynthese mittels harnstoffderivaten