DK0930936T4 - Fremgangsmåde til fremstilling af mikrokapsler af aktivstoffer overtrukket med en polymer samt hidtil ukendte mikrokapsler, der især er fremstillet ved fremgangsmåden - Google Patents
Fremgangsmåde til fremstilling af mikrokapsler af aktivstoffer overtrukket med en polymer samt hidtil ukendte mikrokapsler, der især er fremstillet ved fremgangsmådenInfo
- Publication number
- DK0930936T4 DK0930936T4 DK97942080T DK97942080T DK0930936T4 DK 0930936 T4 DK0930936 T4 DK 0930936T4 DK 97942080 T DK97942080 T DK 97942080T DK 97942080 T DK97942080 T DK 97942080T DK 0930936 T4 DK0930936 T4 DK 0930936T4
- Authority
- DK
- Denmark
- Prior art keywords
- microcapsules
- polymer
- supercritical
- solvent
- active substance
- Prior art date
Links
- 239000003094 microcapsule Substances 0.000 title abstract 6
- 239000013543 active substance Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 229920000642 polymer Polymers 0.000 title abstract 4
- 229920006112 polar polymer Polymers 0.000 abstract 4
- 239000007788 liquid Substances 0.000 abstract 3
- 239000003960 organic solvent Substances 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 2
- 239000004952 Polyamide Substances 0.000 abstract 1
- 229920002732 Polyanhydride Polymers 0.000 abstract 1
- 229920001710 Polyorthoester Polymers 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- 229920002678 cellulose Chemical class 0.000 abstract 1
- 239000001913 cellulose Chemical class 0.000 abstract 1
- 238000005354 coacervation Methods 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 125000005395 methacrylic acid group Chemical group 0.000 abstract 1
- 229920002627 poly(phosphazenes) Polymers 0.000 abstract 1
- 229920002647 polyamide Polymers 0.000 abstract 1
- 229920000728 polyester Polymers 0.000 abstract 1
- 229920006254 polymer film Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000011877 solvent mixture Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9611665A FR2753639B1 (fr) | 1996-09-25 | 1996-09-25 | Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede |
| PCT/FR1997/001674 WO1998013136A1 (fr) | 1996-09-25 | 1997-09-24 | Procede de preparation de microcapsules de matieres actives enrobees par un polymere et nouvelles microcapsules notamment obtenues selon le procede |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK0930936T3 DK0930936T3 (da) | 2000-11-06 |
| DK0930936T4 true DK0930936T4 (da) | 2003-12-22 |
Family
ID=9496041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97942080T DK0930936T4 (da) | 1996-09-25 | 1997-09-24 | Fremgangsmåde til fremstilling af mikrokapsler af aktivstoffer overtrukket med en polymer samt hidtil ukendte mikrokapsler, der især er fremstillet ved fremgangsmåden |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6183783B1 (de) |
| EP (1) | EP0930936B2 (de) |
| JP (1) | JP3509105B2 (de) |
| AT (1) | ATE194926T1 (de) |
| CA (1) | CA2267091C (de) |
| DE (1) | DE69702666T3 (de) |
| DK (1) | DK0930936T4 (de) |
| ES (1) | ES2149613T5 (de) |
| FR (1) | FR2753639B1 (de) |
| GR (1) | GR3034627T3 (de) |
| PT (1) | PT930936E (de) |
| WO (1) | WO1998013136A1 (de) |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2797398B1 (fr) * | 1999-08-11 | 2002-10-18 | Mainelab | Microparticules pour administration pulmonaire |
| GB9920558D0 (en) * | 1999-08-31 | 1999-11-03 | Bradford Particle Design Ltd | Methods for particle formation and their products |
| IT1318380B1 (it) * | 2000-03-09 | 2003-08-25 | Intercos Italiana | Polvere cosmetica rivestita. |
| FR2809309B1 (fr) * | 2000-05-23 | 2004-06-11 | Mainelab | Microspheres a liberation prolongee pour administration injectable |
| US6967028B2 (en) * | 2000-07-31 | 2005-11-22 | Mainelab | Prolonged release microspheres for injectable administration |
| US6723363B2 (en) * | 2000-08-29 | 2004-04-20 | The Penn State Research Foundation | Coating foods and pharmaceuticals with an edible polymer using carbon dioxide |
| GB0027357D0 (en) | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
| EP1401404B1 (de) * | 2001-05-30 | 2008-04-16 | Csir | Verfahren zur verkapselung eines wirkstoffs |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| FR2830760B1 (fr) * | 2001-10-12 | 2004-06-04 | Pf Medicament | Procede de preparation d'un compose d'interaction de substances actives avec un support poreux par fluide supercritique |
| GB0205868D0 (en) * | 2002-03-13 | 2002-04-24 | Univ Nottingham | Polymer composite with internally distributed deposition matter |
| FR2837724B1 (fr) * | 2002-03-28 | 2005-01-28 | Centre Nat Rech Scient | Capsules composites biocompatibles |
| US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
| US7033602B1 (en) * | 2002-06-21 | 2006-04-25 | Advanced Cardiovascular Systems, Inc. | Polycationic peptide coatings and methods of coating implantable medical devices |
| US7070798B1 (en) | 2002-06-21 | 2006-07-04 | Advanced Cardiovascular Systems, Inc. | Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine |
| US7217426B1 (en) | 2002-06-21 | 2007-05-15 | Advanced Cardiovascular Systems, Inc. | Coatings containing polycationic peptides for cardiovascular therapy |
| US8506617B1 (en) | 2002-06-21 | 2013-08-13 | Advanced Cardiovascular Systems, Inc. | Micronized peptide coated stent |
| US7011842B1 (en) | 2002-06-21 | 2006-03-14 | Advanced Cardiovascular Systems, Inc. | Polycationic peptide coatings and methods of making the same |
| US6994867B1 (en) | 2002-06-21 | 2006-02-07 | Advanced Cardiovascular Systems, Inc. | Biocompatible carrier containing L-arginine |
| US7794743B2 (en) * | 2002-06-21 | 2010-09-14 | Advanced Cardiovascular Systems, Inc. | Polycationic peptide coatings and methods of making the same |
| US7056523B1 (en) | 2002-06-21 | 2006-06-06 | Advanced Cardiovascular Systems, Inc. | Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine |
| US6998051B2 (en) * | 2002-07-03 | 2006-02-14 | Ferro Corporation | Particles from supercritical fluid extraction of emulsion |
| AU2003253508A1 (en) * | 2002-07-15 | 2004-02-02 | Feyecon Development And Implementation B.V. | Method for particle precipitation using near-critical and supercritical antisolvents |
| US6966990B2 (en) * | 2002-10-11 | 2005-11-22 | Ferro Corporation | Composite particles and method for preparing |
| US7094256B1 (en) | 2002-12-16 | 2006-08-22 | Advanced Cardiovascular Systems, Inc. | Coatings for implantable medical device containing polycationic peptides |
| WO2004058844A1 (ja) * | 2002-12-25 | 2004-07-15 | E-Tec Co., Ltd. | 樹脂微粒子及び樹脂マイクロカプセル、並びにそれらの製造方法 |
| US7083748B2 (en) * | 2003-02-07 | 2006-08-01 | Ferro Corporation | Method and apparatus for continuous particle production using supercritical fluid |
| DE10306604A1 (de) * | 2003-02-18 | 2004-08-26 | Goldschmidt Ag | Kosmetische Zubereitungen mit Wirkstoffen in Mikrokapseln |
| FR2854079B1 (fr) | 2003-04-25 | 2007-11-30 | Pf Medicament | Procede de preparation de complexes moleculaires |
| WO2004098561A2 (en) | 2003-05-08 | 2004-11-18 | Nektar Therapeutics Uk Ltd | Particulate materials |
| FR2857263B1 (fr) * | 2003-07-09 | 2005-09-09 | Sanofi Synthelabo | Nouvelle composition pharmaceutique solide comprenant de l'amisulpride |
| FR2857592B1 (fr) * | 2003-07-18 | 2006-02-24 | Sod Conseils Rech Applic | Nouveau procede de preparation de microparticules |
| US20080226704A1 (en) * | 2004-03-23 | 2008-09-18 | Makoto Kigoshi | Method of Producing Coated Fine Particles |
| JP2005279334A (ja) * | 2004-03-26 | 2005-10-13 | Kao Corp | 複合化粒子の製造方法 |
| US7507823B2 (en) | 2004-05-06 | 2009-03-24 | Bristol-Myers Squibb Company | Process of making aripiprazole particles |
| FR2874836B1 (fr) * | 2004-09-09 | 2007-04-27 | Pierre Fabre Medicament Sa | Procede d'enrobage de poudres |
| ES2285605T3 (es) * | 2005-06-11 | 2007-11-16 | Tutech Innovation Gmbh | Procedimiento para la microencapsulacion de sustancias organicas en forma de particula mediante rociado de un gas soporte hipercritico inerte junto con material de recubrimiento para las sustancias organicas en un lecho fluidizado de alta presion en un autoclave. |
| WO2007011989A2 (en) * | 2005-07-15 | 2007-01-25 | Map Pharmaceuticals, Inc. | Multiple active pharmaceutical ingredients combined in discrete inhalation particles and formulations thereof |
| EP1904219A4 (de) * | 2005-07-15 | 2011-07-27 | Map Pharmaceuticals Inc | Teilchenbildungsverfahren |
| EP1757361A1 (de) * | 2005-08-23 | 2007-02-28 | Feyecon Development & Implementation B.V. | Verfahren zur Herstellung von Kapseln durch Ausfällung |
| ATE481165T1 (de) * | 2005-12-22 | 2010-10-15 | Inst Nat Sante Rech Med | Verfahren zur herstellung von teilchen aus einer emulsion in überkritischem oder flüssigem co2 |
| KR100802278B1 (ko) * | 2006-12-26 | 2008-02-11 | 재단법인서울대학교산학협력재단 | 분자회합이론에 의한 초임계유체를 이용한 비타민 케이를 함유하는 나노구조체 제조방법 |
| DK2425820T3 (en) | 2007-02-11 | 2015-07-13 | Map Pharmaceuticals Inc | A method for the therapeutic administration of DHE in order to enable quick relief of migraine, while minimizing the adverse event profile |
| US9186640B2 (en) * | 2007-08-28 | 2015-11-17 | Pepsico, Inc. | Delivery and controlled release of encapsulated lipophilic nutrients |
| US20100272859A1 (en) * | 2007-08-28 | 2010-10-28 | Pepsico, Inc. | Delivery and controlled release of encapsulated water-insoluble flavorants |
| FR2925488B1 (fr) * | 2007-12-19 | 2011-12-23 | Snpe Materiaux Energetiques | Desensibilisation par enrobage de cristaux de substances energetiques explosives ; cristaux de telles substances enrobes, materiaux energetiques. |
| GB0812742D0 (en) * | 2008-07-11 | 2008-08-20 | Critical Pharmaceuticals Ltd | Process |
| CA2730760A1 (en) * | 2008-07-16 | 2010-01-21 | Surmodics Pharmaceuticals, Inc. | Process for preparing microparticles containing bioactive peptides |
| CN102170871B (zh) * | 2008-07-31 | 2013-04-17 | 费伊肯有限公司 | 微胶囊化物及其制备方法 |
| US20100291221A1 (en) * | 2009-05-15 | 2010-11-18 | Robert Owen Cook | Method of administering dose-sparing amounts of formoterol fumarate-budesonide combination particles by inhalation |
| US9808030B2 (en) | 2011-02-11 | 2017-11-07 | Grain Processing Corporation | Salt composition |
| KR102152751B1 (ko) * | 2012-09-28 | 2020-09-07 | (주)아모레퍼시픽 | 식물 유래 당단백질을 포함하는 마이크로캡슐 |
| CA2895816C (en) | 2012-12-21 | 2021-02-23 | Map Pharmaceuticals, Inc. | 8'-hydroxy-dihydroergotamine compounds and compositions |
| GB201317756D0 (en) * | 2013-10-08 | 2013-11-20 | Critical Pharmaceuticals Ltd | New process |
| JP6516980B2 (ja) * | 2014-07-29 | 2019-05-22 | 学校法人福岡大学 | 二酸化炭素と親二酸化炭素系界面活性剤を用いた機能性高分子複合化粒子及びその製造方法 |
| RU2710193C1 (ru) * | 2019-02-12 | 2019-12-24 | Федеральное государственное унитарное предприятие "Центральный научно-исследовательский институт химии и механики" (ФГУП "ЦНИИХМ") | Способ инкапсулирования частиц твердых реакционно-способных веществ |
| JP2025056807A (ja) * | 2022-03-04 | 2025-04-09 | 株式会社トクヤマ | 超臨界液体を用いて製造される微小中空粒子 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3744329A1 (de) * | 1987-12-28 | 1989-07-06 | Schwarz Pharma Gmbh | Verfahren zur herstellung einer mindestens einen wirkstoff und einen traeger umfassenden zubereitung |
| AU624421B2 (en) † | 1988-10-05 | 1992-06-11 | Pharmacia & Upjohn Company | Finely divided solid crystalline powders via precipitation into an anti-solvent |
| DE4004430A1 (de) * | 1990-02-09 | 1991-08-14 | Schering Ag | Aus polyaldehyden aufgebaute kontrastmittel |
| DE4041563A1 (de) | 1990-12-22 | 1992-06-25 | Sanol Arznei Schwarz Gmbh | Verfahren zur herstellung wirkstoffhaltiger mikropartikel aus hydrolytisch abbaubaren polymeren |
| US6063910A (en) * | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
| GB9313642D0 (en) † | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
| GB9413202D0 (en) † | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
| EP0706821A1 (de) † | 1994-10-06 | 1996-04-17 | Centre De Microencapsulation | Verfahren zum Beschichten von Partikeln |
| US5667806A (en) * | 1995-06-07 | 1997-09-16 | Emisphere Technologies, Inc. | Spray drying method and apparatus |
| US6143211A (en) † | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
| AU709384B2 (en) † | 1996-03-01 | 1999-08-26 | University Of Kansas, The | Methods and apparatus for particle precipitation and coating using near-critical and supercritical antisolvents |
| US5766637A (en) * | 1996-10-08 | 1998-06-16 | University Of Delaware | Microencapsulation process using supercritical fluids |
-
1996
- 1996-09-25 FR FR9611665A patent/FR2753639B1/fr not_active Expired - Lifetime
-
1997
- 1997-09-24 EP EP97942080A patent/EP0930936B2/de not_active Expired - Lifetime
- 1997-09-24 US US09/269,173 patent/US6183783B1/en not_active Expired - Lifetime
- 1997-09-24 DK DK97942080T patent/DK0930936T4/da active
- 1997-09-24 JP JP51534098A patent/JP3509105B2/ja not_active Expired - Lifetime
- 1997-09-24 PT PT97942080T patent/PT930936E/pt unknown
- 1997-09-24 CA CA002267091A patent/CA2267091C/fr not_active Expired - Lifetime
- 1997-09-24 AT AT97942080T patent/ATE194926T1/de active
- 1997-09-24 WO PCT/FR1997/001674 patent/WO1998013136A1/fr not_active Ceased
- 1997-09-24 DE DE69702666T patent/DE69702666T3/de not_active Expired - Lifetime
- 1997-09-24 ES ES97942080T patent/ES2149613T5/es not_active Expired - Lifetime
-
2000
- 2000-10-16 GR GR20000402313T patent/GR3034627T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US6183783B1 (en) | 2001-02-06 |
| EP0930936A1 (de) | 1999-07-28 |
| PT930936E (pt) | 2000-12-29 |
| ATE194926T1 (de) | 2000-08-15 |
| GR3034627T3 (en) | 2001-01-31 |
| ES2149613T5 (es) | 2004-05-01 |
| ES2149613T3 (es) | 2000-11-01 |
| EP0930936B2 (de) | 2003-08-27 |
| FR2753639B1 (fr) | 1998-12-11 |
| DE69702666T2 (de) | 2001-04-12 |
| CA2267091C (fr) | 2006-07-04 |
| JP2001504452A (ja) | 2001-04-03 |
| DK0930936T3 (da) | 2000-11-06 |
| DE69702666D1 (de) | 2000-08-31 |
| DE69702666T3 (de) | 2004-05-13 |
| FR2753639A1 (fr) | 1998-03-27 |
| CA2267091A1 (fr) | 1998-04-02 |
| WO1998013136A1 (fr) | 1998-04-02 |
| EP0930936B1 (de) | 2000-07-26 |
| JP3509105B2 (ja) | 2004-03-22 |
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