DK0935417T3 - Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré - Google Patents

Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré

Info

Publication number
DK0935417T3
DK0935417T3 DK97912779T DK97912779T DK0935417T3 DK 0935417 T3 DK0935417 T3 DK 0935417T3 DK 97912779 T DK97912779 T DK 97912779T DK 97912779 T DK97912779 T DK 97912779T DK 0935417 T3 DK0935417 T3 DK 0935417T3
Authority
DK
Denmark
Prior art keywords
proanthocyanidin polymer
polymer composition
stomach acid
formulations
diarrhea
Prior art date
Application number
DK97912779T
Other languages
English (en)
Inventor
Edward J Rozhon
Atul S Khandwala
Akram Sabouni
Original Assignee
Napo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Napo Pharmaceuticals Inc filed Critical Napo Pharmaceuticals Inc
Application granted granted Critical
Publication of DK0935417T3 publication Critical patent/DK0935417T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK97912779T 1996-10-16 1997-10-14 Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré DK0935417T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73077296A 1996-10-16 1996-10-16
PCT/US1997/018845 WO1998016111A1 (en) 1996-10-16 1997-10-14 Enteric formulations of proanthocyanidin polymer antidiarrheal compositions

Publications (1)

Publication Number Publication Date
DK0935417T3 true DK0935417T3 (da) 2009-08-10

Family

ID=24936755

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97912779T DK0935417T3 (da) 1996-10-16 1997-10-14 Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré

Country Status (14)

Country Link
US (5) US7341744B1 (da)
EP (3) EP2060183A3 (da)
JP (1) JP4195728B2 (da)
KR (1) KR100467532B1 (da)
AT (1) ATE430477T1 (da)
AU (1) AU4988197A (da)
CA (1) CA2269078C (da)
DE (1) DE69739394D1 (da)
DK (1) DK0935417T3 (da)
ES (1) ES2326933T3 (da)
NZ (1) NZ335317A (da)
PT (1) PT935417E (da)
TW (1) TW537898B (da)
WO (1) WO1998016111A1 (da)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2060183A3 (en) * 1996-10-16 2009-06-03 Napo Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
WO2000047062A2 (en) * 1999-02-01 2000-08-17 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same
KR20010108193A (ko) * 1999-02-15 2001-12-07 마사토시 노다 활성성분으로서 프로안토시아니딘을 함유하는에이디피-리보실화 억제제 및 엔테로톡신 타입 세균감염성질환 치료용 조성물
CA2374356C (fr) * 1999-05-17 2012-01-03 D.B.F. Granules contenant une substance vegetale et leur procede de preparation
NZ528883A (en) * 2001-03-28 2005-12-23 Asahi Breweries Ltd Proteotoxin neutralizer
CO5400144A1 (es) 2002-03-11 2004-05-31 Novartis Ag Compuestos organicos
GB0321996D0 (en) * 2003-09-19 2003-10-22 Novartis Nutrition Ag Organic compounds
JP5171038B2 (ja) 2003-10-10 2013-03-27 エティファルム イチョウ・エキスを含む放出持続性の微小顆粒およびそのような顆粒の製造方法
KR100720817B1 (ko) * 2003-12-26 2007-05-21 (주)아모레퍼시픽 식물 추출물을 함유하는 제제 및 그 제조방법
JP2006232752A (ja) * 2005-02-25 2006-09-07 Tokyo Univ Of Marine Science & Technology コレステロール及び中性脂肪吸収抑制剤及びこれを含む食品
PT1698630E (pt) 2005-03-03 2014-09-15 Alfa Wassermann Spa Novas formas polimorfas de rifaximina, processos para a sua produção e a sua utilização nas preparações medicinais
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
US20090076132A1 (en) * 2005-03-11 2009-03-19 Gary Pekoe Antiviral compositions and methods of treatment
JP5167461B2 (ja) * 2005-09-16 2013-03-21 国立医薬品食品衛生研究所長 炎症性腸疾患予防剤
US7351853B2 (en) * 2006-01-23 2008-04-01 Albion Advanced Nutrition Method of manufacturing a granular mineral composition
ES2616012T3 (es) 2006-05-01 2017-06-09 Napo Pharmaceuticals, Inc. Composiciones para tratar o prevenir enfermedad inflamatoria del intestino
US20070254050A1 (en) 2006-05-01 2007-11-01 Quart Barry D Method for treatment of diarrhea-predominant irritable bowel syndrome
SI2241318T1 (sl) * 2006-05-01 2013-04-30 Napo Pharmaceuticals, Inc. Postopek za zdravljenje sindroma iritabilnega ÄŤrevesa s predominantno obstipacijo
US8048413B2 (en) * 2006-05-17 2011-11-01 Helene Huguet Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
WO2008083513A1 (en) * 2006-12-13 2008-07-17 Beijing Gingko-Group Biological Technology Co., Ltd. Black soybean hull extract and process for preparation and use thereof
WO2008115605A1 (en) * 2007-03-22 2008-09-25 Ibix Clear bismuth treatments and methods for making
CN101715349B (zh) * 2007-05-08 2012-07-18 美国Rq生物科技有限公司 治疗革兰氏阴性细菌感染的治疗组合物及方法
US8734867B2 (en) 2007-12-28 2014-05-27 Liveleaf, Inc. Antibacterial having an extract of pomegranate combined with hydrogen peroxide
WO2009094169A1 (en) * 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US20090264433A1 (en) * 2008-04-21 2009-10-22 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Triazine Derivatives
US20090270398A1 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, Compositions and Methods Comprising Pyridazine Derivatives
US8236838B2 (en) * 2008-04-21 2012-08-07 Institute For Oneworld Health Compounds, compositions and methods comprising isoxazole derivatives
WO2009131957A2 (en) * 2008-04-21 2009-10-29 Institute For Oneworld Health Compounds, compositions and methods comprising oxadiazole derivatives
US8807070B2 (en) * 2008-08-07 2014-08-19 Vector Corporation Rotor processor for dry powders
US20100034967A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Dry polymer layering using a rotor processor
US20100034968A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Polymer coating process using dry glidant in a rotor processor
JP2012503005A (ja) * 2008-09-19 2012-02-02 インスティテュート フォア ワンワールド ヘルス イミダゾール誘導体およびトリアゾール誘導体を含む、化合物、組成物ならびに方法。
FR2938430B1 (fr) * 2008-11-14 2011-05-20 Debregeas Et Associes Pharma Granules a base de plantes
RU2571924C2 (ru) * 2009-03-04 2015-12-27 ЛайвЛиф, Инк., Способ и вещество для активируемого сайтом комплексообразования биологических молекул
US8511216B2 (en) * 2009-03-30 2013-08-20 Kanzaki Kokyukoki Mfg. Co., Ltd. Hydraulic actuator unit
US8343976B2 (en) * 2009-04-20 2013-01-01 Institute For Oneworld Health Compounds, compositions and methods comprising pyrazole derivatives
WO2011024049A2 (en) * 2009-08-26 2011-03-03 Glenmark Pharmaceuticals Ltd Method for producing proanthocyanidin polymer compositions for pharmaceutical formulations
US8652534B2 (en) 2009-10-14 2014-02-18 Berry Pharmaceuticals, LLC Compositions and methods for treatment of mammalian skin
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
CN107595836A (zh) 2010-10-31 2018-01-19 纳珀制药公司 用于治疗hiv相关性腹泻的方法和组合物
WO2012101008A1 (en) 2011-01-27 2012-08-02 Glenmark Pharmaceuticals Limited Process for the production of proanthocyanidin polymeric composition
US9895341B2 (en) 2011-04-01 2018-02-20 Ocean Spray Cranberries, Inc. Inflammation and immunity treatments
US9192635B2 (en) 2011-06-24 2015-11-24 Liveleaf, Inc. Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide
US8722040B2 (en) 2011-06-24 2014-05-13 Liveleaf, Inc. Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites
ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
US20150050373A1 (en) * 2012-03-13 2015-02-19 Piramal Enterprises Limited Herbal composition for the treatment of metabolic disorders
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
US8716351B1 (en) 2012-12-23 2014-05-06 Liveleaf, Inc. Methods of treating gastrointestinal spasms
ITMI20130476A1 (it) 2013-03-28 2014-09-29 Novintethical Pharma Sagl Composizioni per il trattamento di disturbi gastro-intestinali a base di complessi di tannini con proteine
CN103536583B (zh) * 2013-11-01 2015-02-25 潍坊医学院 一种原花青素缓释纳米微球及制备方法和应用
DK3546464T3 (da) 2014-05-12 2020-07-27 Alfasigma Spa Fremstilling og anvendelse af den krystallinske form tau af rifaximin solvateret med degme
US20170100429A1 (en) * 2014-05-29 2017-04-13 Jaguar Animal Health, Inc. Methods of Treating Diarrhea in Neonatal and Young Non-Human Animals
WO2015184109A1 (en) * 2014-05-29 2015-12-03 Jaguar Animal Health, Inc. Methods of treating diarrhea in adult non-human animals
US20170095442A1 (en) * 2014-05-29 2017-04-06 Jaguar Animal Health, Inc. Methods of Treating Salmonella-Induced Diarrhea in Non-Human Animals
BR112017014750A2 (pt) * 2015-01-09 2018-06-19 Jaguar Animal Health métodos para tratamento de diarreia em animais de estimação
WO2016138118A1 (en) * 2015-02-26 2016-09-01 Jaguar Animal Health, Inc. Use of croton- or calophyllum-derived proanthocyanidin polymers or botanical extracts in combination with rifaximin for the treatment of diarrhea in non-human animals
CA2976945A1 (en) * 2015-02-26 2016-09-01 Jaguar Health, Inc. Methods of treating diarrhea and promoting intestinal health in non-human animals
WO2018022475A1 (en) * 2016-07-25 2018-02-01 Jaguar Health, Inc Methods of treating porcine epidemic diarrheal virus in piglets
IT201600122310A1 (it) * 2016-12-01 2018-06-01 Sofar Spa Composizione per uso nella terapia di alterazioni dell'intestino
MX2018015344A (es) 2016-12-15 2019-04-29 Nestec Sa Composiciones y metodos que modulan las bacterias en un animal de compañía.
US11857510B2 (en) * 2017-05-31 2024-01-02 Napo Pharmaceuticals, Inc. Methods and compositions for treating congenital diarrhea disorder
JP7328153B2 (ja) * 2017-05-31 2023-08-16 ナポ ファーマシューティカルズ インク． 胆汁酸性下痢、小腸切除又は胆嚢除去及び短腸症候群に関連する下痢を治療するための方法及び組成物
JP7237014B2 (ja) * 2017-12-27 2023-03-10 サントリーホールディングス株式会社 腸管バリア機能改善用組成物
KR20200008826A (ko) 2018-07-17 2020-01-29 성균관대학교산학협력단 대장균을 이용한 단백질가수분해효소 k의 생산 방법
CN109464491B (zh) * 2018-12-03 2022-02-01 四川省畜牧科学研究院 诃子组合物及其在制备预防和/或治疗腹泻和/或乳房炎的产品中的应用
WO2022115481A1 (en) * 2020-11-24 2022-06-02 Napo Pharmaceuticals, Inc. Methods and compositions for treating post-acute infection gastrointestinal disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2377201A1 (fr) * 1977-01-18 1978-08-11 Fabre Sa Pierre Composition pharmaceutique a activite anti-inflammatoire et vasculotrope
SE446940B (sv) 1983-02-16 1986-10-20 Carl Axel Virdalm Medel for bekempande av sjukdomstillstand i matsmeltningsapparaten innehallande skal eller ytterdelar av ber eller frukter
US4698360B1 (en) * 1985-04-09 1997-11-04 D Investigations Pharmacologiq Plant extract with a proanthocyanidins content as therapeutic agent having radical scavenger effect and use thereof
DE3564370D1 (en) 1985-08-30 1988-09-22 Nestle Sa Dietetic product with depurating and antidiarrheal activity and process for its preparation
US5141735A (en) * 1990-06-18 1992-08-25 Hoffman-La Roche, Inc. Substituted amino-benzodiazepines having anitviral activity
US5211944A (en) * 1990-10-12 1993-05-18 Shaman Pharmaceuticals, Inc. Proanthocyanidin polymers having antiviral activity and methods of obtaining same
SI9011933A (sl) 1990-10-15 1998-06-30 TANIN SEVNICA Kemična industrija p.o. Kostanjev taninski ekstrakt, postopek za njegovo pridobivanje in njegova uporaba
US5234922A (en) 1992-09-28 1993-08-10 University Of Iowa Research Foundation Use of sulfonylureas and other potassium channel regulators to treat secretory diarrhea
US5750496A (en) * 1996-08-12 1998-05-12 Utah State University Method of controlling cryptosporidium infectons using protease inhibitors
EP2060183A3 (en) 1996-10-16 2009-06-03 Napo Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer antidiarrheal compositions

Also Published As

Publication number Publication date
US7323195B2 (en) 2008-01-29
CA2269078C (en) 2012-01-24
JP2001524938A (ja) 2001-12-04
WO1998016111A1 (en) 1998-04-23
KR100467532B1 (ko) 2005-01-24
US20140011869A1 (en) 2014-01-09
CA2269078A1 (en) 1998-04-23
US20050019389A1 (en) 2005-01-27
EP2255661A3 (en) 2010-12-22
ES2326933T3 (es) 2009-10-21
PT935417E (pt) 2009-07-17
TW537898B (en) 2003-06-21
EP0935417A1 (en) 1999-08-18
EP0935417B1 (en) 2009-05-06
AU4988197A (en) 1998-05-11
ATE430477T1 (de) 2009-05-15
KR20000049206A (ko) 2000-07-25
EP2060183A2 (en) 2009-05-20
DE69739394D1 (de) 2009-06-18
EP2060183A3 (en) 2009-06-03
JP4195728B2 (ja) 2008-12-10
US8574634B2 (en) 2013-11-05
US20140329896A1 (en) 2014-11-06
US20090148397A1 (en) 2009-06-11
EP2255661A2 (en) 2010-12-01
US7341744B1 (en) 2008-03-11
EP0935417A4 (en) 2006-08-30
NZ335317A (en) 2001-02-23

Similar Documents

Publication Publication Date Title
DK0935417T3 (da) Enteroformuleringer af proanthocyanidin-polymer-sammensætninger mod diarré
WO2001054501A3 (en) Herbicidal composition
AU1974692A (en) Oral-administration forms of a medicament containing pantoprazol
CA2271623A1 (en) Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth
CO4780014A1 (es) Composiciones dentifricas y metodos do y un vehiculo dentrifico bucalmente aceptable y metodo pa ra reducir el manchado y/o la placa y la gingivitis utilizan do dichas composiciones
IL113812A (en) Copolymer-1 pharmaceutical compositions containing it and its use
HUT76330A (en) Antithrombotic peptide-derivates and pharmaceutical compositions comprising them
IL165816A0 (en) Use of cyclooxygenase-2 inhibitors for the manufacture of a medicament for the treatment and prevention of neoplasia
DK0716606T3 (da) Phosphatbindende polymerer til oral indgivelse
PL357089A1 (en) Tartar control denture adhesive compositions
IL175398A0 (en) Steroidal compounds and pharmaceutical compositions containing them for treating oxidative stress and inflammation
WO2001070242A3 (en) Compositions containing molecular iodine
AU7535798A (en) Novel cyclosporin derivatives, preparation and pharmaceutical compositions containing same
AU5669198A (en) Cyclosporin derivative, its preparation and pharmaceutical compositions containing same
CA2214090A1 (en) Oral compositions
DK1142573T3 (da) Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen
BR1100143A (pt) Composto, e, composição farmacêutica.
EP0104768A3 (en) Oral compositions comprising ng-acyl derivatives of arginine
AU1816500A (en) Bleaching compositions
IL99471A0 (en) Pharmaceutical compositions containing pyridylmethylsulphinyl-1h-benzimidazole derivatives as active ingredient therein
AU5704800A (en) Medicinal compositions for preventing or treating diarrhea
NZ290236A (en) Inhibition ofleucotriene biosynthesis and pharmaceutical compositions comprising aryl-urea derivatives
EP0039874A3 (en) Methoxsalen compositions and their preparation
ZA200107908B (en) Compositions containing stannous fluoride for the treatment of hypersensitive teeth.
IT1265086B1 (it) Associazione di macrolidi e antiacidi in composizioni farmaceutiche antiulcera ad azione antibatterica