BR1100143A - Composto, e, composição farmacêutica. - Google Patents

Composto, e, composição farmacêutica.

Info

Publication number
BR1100143A
BR1100143A BR1100143-7A BR1100143A BR1100143A BR 1100143 A BR1100143 A BR 1100143A BR 1100143 A BR1100143 A BR 1100143A BR 1100143 A BR1100143 A BR 1100143A
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
formula
pharmaceutical compositions
compositions containing
Prior art date
Application number
BR1100143-7A
Other languages
English (en)
Inventor
Gerhard Keilhauer
Cynthia Romerdahl
Miguel Fernandez Brana
Xiao-Dong Oian
Peter Bousquet
Jose Maria Castellano Berlanga
Marina Moran Moset
Maria Jesus Perez De Vega
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR1100143A publication Critical patent/BR1100143A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/14—Aza-phenalenes, e.g. 1,8-naphthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR1100143-7A 1993-08-18 1997-02-21 Composto, e, composição farmacêutica. BR1100143A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10894993A 1993-08-18 1993-08-18

Publications (1)

Publication Number Publication Date
BR1100143A true BR1100143A (pt) 2000-03-14

Family

ID=22324990

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9407257A BR9407257A (pt) 1993-08-18 1994-08-08 Composto do tipo bis-naftalimida composição farmacêutica processo para tratamento de um tumor em mamifero uso do composto do tipo bis-naftalimida e processo para a preparação compostos do tipo bis-naftalimida
BR1100143-7A BR1100143A (pt) 1993-08-18 1997-02-21 Composto, e, composição farmacêutica.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BR9407257A BR9407257A (pt) 1993-08-18 1994-08-08 Composto do tipo bis-naftalimida composição farmacêutica processo para tratamento de um tumor em mamifero uso do composto do tipo bis-naftalimida e processo para a preparação compostos do tipo bis-naftalimida

Country Status (28)

Country Link
US (3) US5616589A (pt)
EP (1) EP0714387B1 (pt)
JP (1) JPH09501662A (pt)
KR (1) KR960703863A (pt)
CN (1) CN1039414C (pt)
AT (1) ATE166647T1 (pt)
AU (1) AU677696B2 (pt)
BR (2) BR9407257A (pt)
CA (1) CA2169059A1 (pt)
CZ (1) CZ34296A3 (pt)
DE (1) DE69410614T2 (pt)
DK (1) DK0714387T3 (pt)
ES (1) ES2116612T3 (pt)
FI (1) FI960658A0 (pt)
HR (1) HRP940458B1 (pt)
HU (1) HU219232B (pt)
IL (1) IL110460A (pt)
NO (1) NO305554B1 (pt)
NZ (1) NZ271374A (pt)
PH (1) PH31395A (pt)
PL (1) PL313078A1 (pt)
RU (1) RU2138484C1 (pt)
SG (1) SG64906A1 (pt)
SI (1) SI9420053A (pt)
TW (1) TW408112B (pt)
UA (1) UA42733C2 (pt)
WO (1) WO1995005365A1 (pt)
ZA (1) ZA946196B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5703089A (en) * 1994-04-28 1997-12-30 Knoll Aktiengesellschaft Dihydrodibenzisoquinolinediones
AU728523C (en) * 1996-10-21 2001-08-09 Nps Pharmaceuticals, Inc. Neurotrophin antagonist compositions
US6420344B1 (en) 1999-03-16 2002-07-16 The Regents Of The University Of California Glycosylated polyamines
US6531454B1 (en) 1999-03-16 2003-03-11 The Regents Of The University Of California Glycosylated polyamines and methods of use therefor
US6468990B1 (en) 1999-05-17 2002-10-22 Queen's University At Kingston Method of inhibiting binding of nerve growth factor to p75 NTR receptor
US6492380B1 (en) 1999-05-17 2002-12-10 Queen's University At Kingston Method of inhibiting neurotrophin-receptor binding
AU2001240054B2 (en) 2000-03-07 2005-08-11 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-Naphthalimide Imidazo[4,5,1-de]acridones with Anti-Tumor Activity
CA2586320A1 (en) 2003-11-05 2005-05-19 Photobiomed Corporation Bonding tissues and cross-linking proteins with naphthalimide compounds
JP2007536283A (ja) * 2004-05-05 2007-12-13 ユニバイオスクリーン エス．アー． ナフタルイミド誘導体、それらの製造方法、およびそれらの医薬組成物
JP4993645B2 (ja) 2004-12-01 2012-08-08 ジェネンテック， インコーポレイテッド 抗体薬剤結合体および方法
US7947839B2 (en) 2004-12-01 2011-05-24 Genentech, Inc. Heterocyclic-substituted bis-1,8 naphthalimide compounds, antibody drug conjugates, and methods of use
US20070134243A1 (en) * 2004-12-01 2007-06-14 Gazzard Lewis J Antibody drug conjugates and methods
US20070099900A1 (en) 2005-09-15 2007-05-03 Painceptor Pharma Corporation Methods of modulating neurotrophin-mediated activity
US8420665B2 (en) 2008-01-11 2013-04-16 Northwestern University Anti-cancer compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3535496A1 (de) * 1985-10-04 1987-04-16 Bayer Ag Verfahren zur fluoreszenzloeschung und neue kationische naphthalin-peri-dicarbonsaeureimid-derivate
DE3707651A1 (de) * 1987-03-10 1988-09-22 Knoll Ag Bis-naphthalimide, ihre herstellung und verwendung
US5086052A (en) * 1987-07-17 1992-02-04 Abbott Laboratories Substituted 1,4,5,6-tetrahydro-2H-pyridazin-3-one and -3-thione compounds having lipoxygenase inhibitory activity
US5086059A (en) * 1990-06-07 1992-02-04 Du Pont Merck Pharmaceutical Company Bis-naphthalimides as anticancer agents
US5206249A (en) * 1991-03-27 1993-04-27 Du Pont Merck Pharmaceutical Company Bis-naphthalimides containing amino-acid derived linkers as anticancer agents
WO1993012092A1 (en) * 1991-12-11 1993-06-24 The Du Pont Merck Pharmaceutical Company Highly water soluble bis-naphthalimides useful as anticancer agents
DE4232739A1 (de) * 1992-09-30 1994-03-31 Knoll Ag Neue asymmetrisch substituierte bis-Naphthalimide

Also Published As

Publication number Publication date
NZ271374A (en) 1997-05-26
EP0714387A1 (en) 1996-06-05
US5616589A (en) 1997-04-01
HRP940458A2 (en) 1997-06-30
TW408112B (en) 2000-10-11
NO960632L (no) 1996-02-16
SI9420053A (en) 1996-08-31
HU9600360D0 (en) 1996-04-29
PL313078A1 (en) 1996-05-27
ATE166647T1 (de) 1998-06-15
IL110460A0 (en) 1994-10-21
PH31395A (en) 1998-10-29
US5981753A (en) 1999-11-09
FI960658L (fi) 1996-02-14
ES2116612T3 (es) 1998-07-16
NO305554B1 (no) 1999-06-21
DE69410614D1 (de) 1998-07-02
DE69410614T2 (de) 1998-09-24
AU677696B2 (en) 1997-05-01
NO960632D0 (no) 1996-02-16
FI960658A7 (fi) 1996-02-14
WO1995005365A1 (en) 1995-02-23
HUT73529A (en) 1996-08-28
CZ34296A3 (en) 1996-08-14
CN1039414C (zh) 1998-08-05
JPH09501662A (ja) 1997-02-18
US5789418A (en) 1998-08-04
FI960658A0 (fi) 1996-02-14
SG64906A1 (en) 1999-05-25
EP0714387B1 (en) 1998-05-27
DK0714387T3 (da) 1998-10-12
CA2169059A1 (en) 1995-02-23
HRP940458B1 (en) 2000-02-29
RU2138484C1 (ru) 1999-09-27
ZA946196B (en) 1996-02-19
AU7498494A (en) 1995-03-14
BR9407257A (pt) 1996-09-24
CN1132506A (zh) 1996-10-02
IL110460A (en) 2001-01-11
KR960703863A (ko) 1996-08-31
UA42733C2 (uk) 2001-11-15
HU219232B (en) 2001-03-28

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Legal Events

Date Code Title Description
MT Patent procedure suspended until requirement met - articles 230 and 231 of law 9279/96
FGAN Processing applications according to articles 230 and 231 of law 9.279/96: granting
NB Patent issued - articles 230 and 231 of law 9279/96