DK0935598T3 - 5-heteroatom-alkylsubstituerede 3-oxopyrido(1,2-a)benzimidazol-4-carboxamidderivater egnede til behandling af sygdomme i centralnervesystemet - Google Patents
5-heteroatom-alkylsubstituerede 3-oxopyrido(1,2-a)benzimidazol-4-carboxamidderivater egnede til behandling af sygdomme i centralnervesystemetInfo
- Publication number
- DK0935598T3 DK0935598T3 DK97909992T DK97909992T DK0935598T3 DK 0935598 T3 DK0935598 T3 DK 0935598T3 DK 97909992 T DK97909992 T DK 97909992T DK 97909992 T DK97909992 T DK 97909992T DK 0935598 T3 DK0935598 T3 DK 0935598T3
- Authority
- DK
- Denmark
- Prior art keywords
- oxopyrido
- benzimidazole
- heteroatom
- substituted
- alkyl
- Prior art date
Links
- DUWLQVURMIPTQJ-UHFFFAOYSA-N 3-oxo-5h-pyrido[1,2-a]benzimidazole-4-carboxamide Chemical class N1C2=CC=CC=C2N2C1=C(C(=O)N)C(=O)C=C2 DUWLQVURMIPTQJ-UHFFFAOYSA-N 0.000 title 1
- 208000015114 central nervous system disease Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2751196P | 1996-10-07 | 1996-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0935598T3 true DK0935598T3 (da) | 2004-03-29 |
Family
ID=21838133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97909992T DK0935598T3 (da) | 1996-10-07 | 1997-10-03 | 5-heteroatom-alkylsubstituerede 3-oxopyrido(1,2-a)benzimidazol-4-carboxamidderivater egnede til behandling af sygdomme i centralnervesystemet |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5817668A (da) |
| EP (1) | EP0935598B1 (da) |
| JP (1) | JP2001501949A (da) |
| AR (1) | AR013844A1 (da) |
| AT (1) | ATE256126T1 (da) |
| AU (1) | AU719333B2 (da) |
| CA (1) | CA2267943A1 (da) |
| DE (1) | DE69726749T2 (da) |
| DK (1) | DK0935598T3 (da) |
| ES (1) | ES2212081T3 (da) |
| NZ (1) | NZ335060A (da) |
| PT (1) | PT935598E (da) |
| WO (1) | WO1998015553A1 (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922731A (en) * | 1997-06-30 | 1999-07-13 | Ortho Pharmaceutical Corporation | 5- (heteroaryl)alkyl!-3-oxo-pyrido 1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders |
| WO1999018105A1 (en) * | 1997-10-07 | 1999-04-15 | Ortho-Mcneil Pharmaceutical, Inc. | Dipyridoimidazolderivatives useful in treating central nervous system disorders |
| WO1999018104A1 (en) * | 1997-10-07 | 1999-04-15 | Ortho-Mcneil Pharmaceutical, Inc. | Naphtho-imidazo[1,2-a]pyridine derivatives, their preparation and their use in treating central nervous system disorders |
| ES2246090T3 (es) * | 1998-08-25 | 2006-02-01 | Neurogen Corporation | Oxo-piridoimidazol-carboxamidas: ligandos del receptor cerebral gaba. |
| US6177569B1 (en) | 1998-08-25 | 2001-01-23 | Neurogen Corporation | Oxo-pyridoimidazole-carboxamides: GABA brain receptor ligands |
| EP1200433B1 (en) | 1999-08-02 | 2006-03-22 | Ortho-McNeil Pharmaceutical, Inc. | C-6 RING-SUBSTITUTED PYRIDO[1,2-a]BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATING CENTRAL NERVOUS SYSTEM DISORDERS |
| GB0008696D0 (en) | 2000-04-07 | 2000-05-31 | Merck Sharp & Dohme | Therapeutic agents |
| CA2508165C (en) * | 2002-12-06 | 2014-05-06 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
| US7221138B2 (en) | 2005-09-27 | 2007-05-22 | Saifun Semiconductors Ltd | Method and apparatus for measuring charge pump output current |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0656002T3 (da) * | 1992-08-19 | 2000-11-27 | Mcneilab Inc | 3-Oxo-pyrido(1,2-a)benzimidazol-4-carboxyl- og 4-oxo-azepino(1,2-a)benzimidazol-5-carboxylderivater, som er anvendelige ved |
| US5521200A (en) * | 1993-12-30 | 1996-05-28 | Ho; Winston | 2-oxo-pyrrolo[1,2-A]benzimidazole-3-carboxyl derivatives useful in treating central nervous system disorders |
-
1997
- 1997-10-03 AT AT97909992T patent/ATE256126T1/de not_active IP Right Cessation
- 1997-10-03 NZ NZ335060A patent/NZ335060A/xx unknown
- 1997-10-03 DK DK97909992T patent/DK0935598T3/da active
- 1997-10-03 US US08/943,578 patent/US5817668A/en not_active Expired - Lifetime
- 1997-10-03 EP EP97909992A patent/EP0935598B1/en not_active Expired - Lifetime
- 1997-10-03 CA CA002267943A patent/CA2267943A1/en not_active Abandoned
- 1997-10-03 JP JP10517660A patent/JP2001501949A/ja not_active Withdrawn
- 1997-10-03 PT PT97909992T patent/PT935598E/pt unknown
- 1997-10-03 ES ES97909992T patent/ES2212081T3/es not_active Expired - Lifetime
- 1997-10-03 WO PCT/US1997/018045 patent/WO1998015553A1/en not_active Ceased
- 1997-10-03 DE DE69726749T patent/DE69726749T2/de not_active Expired - Fee Related
- 1997-10-03 AU AU47473/97A patent/AU719333B2/en not_active Ceased
- 1997-10-06 AR ARP970104602A patent/AR013844A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP0935598A1 (en) | 1999-08-18 |
| AR013844A1 (es) | 2001-01-31 |
| WO1998015553A1 (en) | 1998-04-16 |
| AU719333B2 (en) | 2000-05-04 |
| EP0935598B1 (en) | 2003-12-10 |
| PT935598E (pt) | 2004-03-31 |
| ATE256126T1 (de) | 2003-12-15 |
| CA2267943A1 (en) | 1998-04-16 |
| NZ335060A (en) | 2000-05-26 |
| US5817668A (en) | 1998-10-06 |
| DE69726749D1 (de) | 2004-01-22 |
| DE69726749T2 (de) | 2005-07-21 |
| AU4747397A (en) | 1998-05-05 |
| JP2001501949A (ja) | 2001-02-13 |
| ES2212081T3 (es) | 2004-07-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IS5113A (is) | Notkun antagónista CB1-viðtaka til meðhöndlunar löngunartruflana | |
| NO306977B1 (no) | Anvendelse av tienol[1,5]benzodiazepin for behandling av tilstander i mave/tarmkanalen | |
| DK0751129T6 (da) | Substituerede dihydrodibenzo(b,f)azepiner, fremgangsmåde til fremstilling deraf, deres anvendelse i behandlingen af nogle lidelser i centralnervesystemet og farmaceutiske sammensætninger indeholdende disse | |
| DK0937055T3 (da) | Fremgangsmåde til fremstilling af d,I-alfa-tocopherol | |
| DK0908458T3 (da) | Substituerede pyridylmethylpiperazin- og piperidinderivater, deres fremstilling samt deres anvendelse til behandling af lidelser i centralnervesystemet (CNS) | |
| AU4674797A (en) | Phenylalaninol derivatives for the treatment of central nervous system disorders | |
| DK1105390T3 (da) | Imidazo(1,2a)pyridinderivater til behandling af gastrointestinale sygdomme | |
| EE200000391A (et) | Triasiiniühendid kesknärvisüsteemihäirete raviks | |
| DK0983275T3 (da) | Nye triptolidderivater, der er nyttige til behandling af autoimmune sygdomme | |
| NO971512D0 (no) | Nye pyrimido(1,2-a)indoler | |
| ATE256126T1 (de) | 5-heteroatom-alkyl substituierte 3-oxo-pyrido(1,2-a)benzimidazol-4-carboxamid derivate zur behandlung zentral nervöser system störungen | |
| DE69735417D1 (de) | 2,5-dihydroxybenzylsulfonderivate zur behandlung von sexuellen störungen | |
| NO991734D0 (no) | Pyrazolinoner for behandling av potensforstyrrelser | |
| BR9712030A (pt) | Uso de benzopiranÄis para o tratamento de desordens neurolÄgicas | |
| DK0946514T3 (da) | Fremgangsmåde til fremstilling af n-substituerede 3-hydroxypyrazoler | |
| DK0815092T3 (da) | Fremgangsmåde til fremstilling af 1,2-benzisothiazolin-3-oner | |
| DK1121356T3 (da) | 3-tetrahydropyridin-4-yl-indoler til behandling af psykotiske lidelser | |
| DE69923464D1 (de) | Benzenesulfonamide derivate in kombination mit beta-blockern zur behandlung von störungen des autonomen nervensystems | |
| DK0735043T3 (da) | Fremgangsmåde til fremstilling af 2-substitueret 3,3-difluorfuran | |
| NO990450D0 (no) | Behandling av sinnslidelser | |
| NO985535L (no) | FremgangsmÕte for fremstilling av 1,3-alkandioler | |
| NO984189D0 (no) | Fremgangsmåte for behandling av bipolar forstyrrelse | |
| DK1011678T3 (da) | Anvendelse af mecamylamin til behandling af nikotin-responsive neuropsykiatriske lidelser | |
| NO20012538D0 (no) | Anvendelse av N-substituerte azabicycloalkanderivater for behandling av forstyrrelser i sentralnervesystemet | |
| DK0964681T3 (da) | Antikonvulsive derivater til behandling af psoriasis |