DK0944397T3 - Iscom eller iscom-matrix indeholdende hydrofobe receptormolekyler til antigene stoffer - Google Patents

Iscom eller iscom-matrix indeholdende hydrofobe receptormolekyler til antigene stoffer

Info

Publication number
DK0944397T3
DK0944397T3 DK97905539T DK97905539T DK0944397T3 DK 0944397 T3 DK0944397 T3 DK 0944397T3 DK 97905539 T DK97905539 T DK 97905539T DK 97905539 T DK97905539 T DK 97905539T DK 0944397 T3 DK0944397 T3 DK 0944397T3
Authority
DK
Denmark
Prior art keywords
iscom
receptor molecules
antigenic substances
pct
matrix containing
Prior art date
Application number
DK97905539T
Other languages
Danish (da)
English (en)
Inventor
Bror Morein
Bengtsson Karin Loevgren
Jill Ekstroem
Original Assignee
Bengtsson Karin Loevgren
Jill Ekstroem
Bror Morein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bengtsson Karin Loevgren, Jill Ekstroem, Bror Morein filed Critical Bengtsson Karin Loevgren
Application granted granted Critical
Publication of DK0944397T3 publication Critical patent/DK0944397T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6901—Conjugates being cells, cell fragments, viruses, ghosts, red blood cells or viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Nanotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DK97905539T 1996-02-21 1997-02-20 Iscom eller iscom-matrix indeholdende hydrofobe receptormolekyler til antigene stoffer DK0944397T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9600648A SE9600648D0 (sv) 1996-02-21 1996-02-21 Receptorbimdande enhet
PCT/SE1997/000287 WO1997030726A1 (en) 1996-02-21 1997-02-20 Iscom or iscom-matrix comprising hydrophobic receptor molecules for antigenic substances

Publications (1)

Publication Number Publication Date
DK0944397T3 true DK0944397T3 (da) 2004-06-01

Family

ID=20401482

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97905539T DK0944397T3 (da) 1996-02-21 1997-02-20 Iscom eller iscom-matrix indeholdende hydrofobe receptormolekyler til antigene stoffer

Country Status (12)

Country Link
US (1) US6027732A (de)
EP (1) EP0944397B1 (de)
AT (1) ATE258066T1 (de)
AU (1) AU718443B2 (de)
BR (1) BR9707638A (de)
CA (1) CA2247103C (de)
DE (1) DE69727314T2 (de)
DK (1) DK0944397T3 (de)
ES (1) ES2214608T3 (de)
NZ (1) NZ331418A (de)
SE (1) SE9600648D0 (de)
WO (1) WO1997030726A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6207646B1 (en) * 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US20030026782A1 (en) * 1995-02-07 2003-02-06 Arthur M. Krieg Immunomodulatory oligonucleotides
US6406705B1 (en) * 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
US20030022854A1 (en) 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
US6693086B1 (en) * 1998-06-25 2004-02-17 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
DE60044236D1 (de) * 1999-02-17 2010-06-02 Csl Ltd Immunogene komplexe und methoden in bezug auf diese
DE60039715D1 (de) * 1999-11-19 2008-09-11 Csl Ltd Hcv-impfstoff zusammensetzungen
SE0003538D0 (sv) * 2000-09-29 2000-09-29 Isconova Ab New immunogenic complex
US7713942B2 (en) * 2001-04-04 2010-05-11 Nordic Vaccine Technology A/S Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
US20030138434A1 (en) * 2001-08-13 2003-07-24 Campbell Robert L. Agents for enhancing the immune response
ATE361097T1 (de) * 2002-01-15 2007-05-15 Bio Life Science Forschungs & Entwicklungsgesellschaft Mbh Orale vakzinierung mit dem tumor-antigen-mimotop gln-met-trp-ala-pro-gln-trp-gly-pro-asp
EP1608403A2 (de) * 2003-04-02 2005-12-28 Coley Pharmaceutical Group, Ltd. Immunostimulatorische nukleinsäure öl-in-wasser emulsionen zur topischen anwendung
US20050013812A1 (en) * 2003-07-14 2005-01-20 Dow Steven W. Vaccines using pattern recognition receptor-ligand:lipid complexes
TWI235440B (en) * 2004-03-31 2005-07-01 Advanced Semiconductor Eng Method for making leadless semiconductor package
JP2008506789A (ja) * 2004-07-18 2008-03-06 シーエスエル、リミテッド インターフェロン−ガンマ応答強化を誘発するための免疫刺激複合体及びオリゴヌクレオチド処方物
EP2468300B1 (de) 2006-09-26 2017-12-20 Infectious Disease Research Institute Impfstoffzusammensetzung mit einem synthetischen Adjuvans
US20090181078A1 (en) 2006-09-26 2009-07-16 Infectious Disease Research Institute Vaccine composition containing synthetic adjuvant
ES2325243B1 (es) * 2008-02-27 2011-05-04 Universidad De Granada Antigeno recombinante.
CA2764374C (en) 2009-06-05 2019-11-19 Infectious Disease Research Institute Synthetic glucopyranosyl lipid adjuvants
NZ616304A (en) 2011-04-08 2016-01-29 Immune Design Corp Immunogenic compositions and methods of using the compositions for inducing humoral and cellular immune responses
PL2811981T3 (pl) 2012-02-07 2019-09-30 Infectious Disease Research Institute Ulepszone formulacje adiuwantowe zawierające agonistę TLR4 oraz sposoby ich zastosowania
SMT201800368T1 (it) 2012-05-16 2018-09-13 Immune Design Corp Vaccini per l'infezione da virus-2 herpes simplex
CA2909221A1 (en) 2013-04-18 2014-10-23 Immune Design Corp. Gla monotherapy for use in cancer treatment
US9463198B2 (en) 2013-06-04 2016-10-11 Infectious Disease Research Institute Compositions and methods for reducing or preventing metastasis
IL310015B2 (en) 2013-12-31 2026-02-01 Access To Advanced Health Inst Single vial formulation
BR112021023726A2 (pt) 2019-05-25 2022-02-15 Infectious Disease Res Inst Composição e método para secagem por pulverização de uma emulsão de vacina adjuvante
EP4058581A1 (de) 2019-11-15 2022-09-21 Infectious Disease Research Institute Rig-i-agonist und adjuvans-formulierung zur tumorbehandlung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2403081A1 (fr) * 1977-09-19 1979-04-13 Merieux Inst Nouveau materiau particulaire, sa preparation et son application, notamment comme medicament
US5178860A (en) * 1989-09-01 1993-01-12 Coopers Animal Health Limited Adjuvant complexes and vaccine made therefrom
NL9002314A (nl) * 1990-10-23 1992-05-18 Nederlanden Staat Immunogene complexen, in het bijzonder iscoms.

Also Published As

Publication number Publication date
EP0944397B1 (de) 2004-01-21
CA2247103A1 (en) 1997-08-28
NZ331418A (en) 2000-03-27
US6027732A (en) 2000-02-22
CA2247103C (en) 2009-01-20
ATE258066T1 (de) 2004-02-15
AU2238397A (en) 1997-09-10
BR9707638A (pt) 2000-01-04
EP0944397A1 (de) 1999-09-29
SE9600648D0 (sv) 1996-02-21
WO1997030726A1 (en) 1997-08-28
AU718443B2 (en) 2000-04-13
DE69727314D1 (de) 2004-02-26
ES2214608T3 (es) 2004-09-16
DE69727314T2 (de) 2004-11-18

Similar Documents

Publication Publication Date Title
AU2238397A (en) Iscom or iscom-matrix comprising hydrophobic receptor molecules for antigenic substances
ES2116530T3 (es) Productos de cuidado personal que contienen silicona.
AU6253898A (en) Use of microparticles combined with submicron oil-in-water emulsions
ES2142463T3 (es) Composicion cosmetica o farmaceutica para uso topico.
WO2006026389A3 (en) Ceramide derivatives as modulators of immunity and autoimmunity
ITRM920590A0 (it) Sistema per la realizzazione distrutture in fibra di carbonio, e procedimento per detto, particolarmente idoneo per applicazioni aeronautiche.
PT1053256E (pt) Anticorpos para o receptor de morte 4 (dr4) e utilizações destes
GB0016918D0 (en) Method of providing an image on a substrate, and an ink for use therein
ATE169317T1 (de) Pyridobismidazole enthaltendes rigid-rod-polymer
DK0633763T3 (da) Kosmetiske eller farmaceutiske sammensætninger indeholdende deacylerede glycerophospholipider til topisk brug
DE69120942D1 (de) Hilfsstoffzusammensetzungen in fester form, dispergieren in wässerigen medien
WO2000003724A1 (en) Preparations for immunotherapy for cancer having bacterial somatic constituent as the active ingredient
DE602005005449D1 (de) Adjuvante zusammensetzungen
IL130954A0 (en) Neurturin receptor
ATE160839T1 (de) Ausfachsystem für wände und verkleidungen im bauwesen
IL114141A (en) Method for preparing cloud stable extract from plant material
ATE145191T1 (de) Azofarbstoffe enthaltende molekularsiebe
DE69901331D1 (de) Kosmetische zusammensetzungen enthaltend einen anionischen tensid vom typ alkylpolyglykosidester und ein galaktomannangummi sowie deren verwendungen
UA29496C2 (uk) Ротор для перемішуючих пристроїв
ZA979590B (en) Use of nanoemulsions based on fluid nonionic amphiUse of nanoemulsions based on fluid nonionic amphiUse of nanoemulsions based on fluid nonionic amphiphilic lipids for keratin fibres. philic lipids for keratin fibres. philic lipids for keratin fibres.
Samain VizieR Online Data Catalog: Ultraviolet Spectrum of the Sun (Samain, 1995)
ITMI932171A1 (it) Procedimento per l'estrazione di colori naturali mediante bentonite
Hojaev et al. Study of Young Star V1331Cyg in Compact Starforming Region
DK0873136T3 (da) Specifik immunforögende faktor med höj fluorescens og fremgangsmåder til anvendelse af samme
ATE328088T1 (de) Transketolase-verwandtes protein