DK0945136T3 - Topisk lægemiddel indeholdende ciclosporin - Google Patents

Topisk lægemiddel indeholdende ciclosporin

Info

Publication number: DK0945136T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical composition; composition containing; drug containing; topical drug; topical administration
Prior art date: 1998-03-12

Application number

DK99104009T

Other languages

English (en)

Inventor

Peter Edgar Dr Heide

Original Assignee

Peter Edgar Dr Heide

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-12

Filing date

1999-03-12

Publication date

2006-01-23

1999-03-12 Application filed by Peter Edgar Dr Heide filed Critical Peter Edgar Dr Heide

2006-01-23 Application granted granted Critical

2006-01-23 Publication of DK0945136T3 publication Critical patent/DK0945136T3/da

Links

PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 2
108010036949 Cyclosporine Proteins 0.000 title abstract 2
229960001265 ciclosporin Drugs 0.000 title abstract 2
229940079593 drug Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
230000000699 topical effect Effects 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 abstract 3
239000008346 aqueous phase Substances 0.000 abstract 2
239000000203 mixture Substances 0.000 abstract 2
239000007908 nanoemulsion Substances 0.000 abstract 2
238000011200 topical administration Methods 0.000 abstract 2
229930105110 Cyclosporin A Natural products 0.000 abstract 1
206010020751 Hypersensitivity Diseases 0.000 abstract 1
102000015696 Interleukins Human genes 0.000 abstract 1
108010063738 Interleukins Proteins 0.000 abstract 1
230000007815 allergy Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
238000001914 filtration Methods 0.000 abstract 1
229960003444 immunosuppressant agent Drugs 0.000 abstract 1
230000001861 immunosuppressant effect Effects 0.000 abstract 1
239000003018 immunosuppressive agent Substances 0.000 abstract 1
239000003112 inhibitor Substances 0.000 abstract 1
230000010534 mechanism of action Effects 0.000 abstract 1
239000012071 phase Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
208000017520 skin disease Diseases 0.000 abstract 1
230000001954 sterilising effect Effects 0.000 abstract 1
238000003756 stirring Methods 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Immunology (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Gastroenterology & Hepatology (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Dispersion Chemistry (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

DK99104009T 1998-03-12 1999-03-12 Topisk lægemiddel indeholdende ciclosporin DK0945136T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19810655A DE19810655A1 (de)	1998-03-12	1998-03-12	Arzneimittel mit einem Gehalt an Ciclosporin

Publications (1)

Publication Number	Publication Date
DK0945136T3 true DK0945136T3 (da)	2006-01-23

Family

ID=7860576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99104009T DK0945136T3 (da)	1998-03-12	1999-03-12	Topisk lægemiddel indeholdende ciclosporin

Country Status (5)

Country	Link
EP (1)	EP0945136B9 (da)
AT (1)	ATE309816T1 (da)
DE (2)	DE19810655A1 (da)
DK (1)	DK0945136T3 (da)
ES (1)	ES2248935T3 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6623517B1 (en) *	1999-02-23	2003-09-23	Deluisa Laura	Eye compress
EP2116228A1 (en)	2001-10-19	2009-11-11	Isotechnika Inc.	Novel cyclosporin analog microemulsion preconcentrates
US7354574B2 (en)	2002-11-07	2008-04-08	Advanced Ocular Systems Limited	Treatment of ocular disease
US7083802B2 (en)	2003-07-31	2006-08-01	Advanced Ocular Systems Limited	Treatment of ocular disease
US20050059583A1 (en)	2003-09-15	2005-03-17	Allergan, Inc.	Methods of providing therapeutic effects using cyclosporin components
JP2007505932A (ja)	2003-09-18	2007-03-15	マクサイト，インコーポレイテッド	経強膜送達
US7083803B2 (en)	2003-09-19	2006-08-01	Advanced Ocular Systems Limited	Ocular solutions
US7087237B2 (en)	2003-09-19	2006-08-08	Advanced Ocular Systems Limited	Ocular solutions
US7135455B2 (en)	2004-11-15	2006-11-14	Allergan, Inc	Methods for the therapeutic use of cyclosporine components
US7151085B2 (en) *	2004-11-15	2006-12-19	Allergan, Inc.	Therapeutic methods using cyclosporine components
US8663639B2 (en)	2005-02-09	2014-03-04	Santen Pharmaceutical Co., Ltd.	Formulations for treating ocular diseases and conditions
WO2006086750A1 (en)	2005-02-09	2006-08-17	Macusight, Inc.	Liquid formulations for treatment of diseases or conditions
PL1904056T3 (pl)	2005-07-18	2009-09-30	Minu Llc	Zastosowanie makrolidu do przywracania czucia rogówkowego
US8492400B2 (en)	2006-02-09	2013-07-23	Santen Pharmaceutical Co., Ltd.	Stable formulations, and methods of their preparation and use
WO2007095486A1 (en) *	2006-02-13	2007-08-23	Allergan, Inc.	Methods of treating blepharospasm using cyclosporine components
CN101443004B (zh)	2006-03-23	2013-03-06	参天制药株式会社	用于与血管通透性有关的疾病或病症的制剂
EP2376103B1 (en)	2009-01-08	2012-12-12	Allergan, Inc.	Cyclosporine compositions for enhancing nail growth
DE102011108948A1 (de)	2011-07-29	2013-01-31	Achim Göpferich	Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61249918A (ja) *	1985-04-26	1986-11-07	Yutaka Mizushima	点眼剤
DE68900991D1 (de) *	1988-01-29	1992-04-23	Sankyo Co	Cyclosporin-zusammensetzungen.
US5342625A (en) *	1988-09-16	1994-08-30	Sandoz Ltd.	Pharmaceutical compositions comprising cyclosporins
IL101007A (en) *	1992-02-18	1997-08-14	Pharmos Ltd	Dry stable compositions prepared by lyophilization
DE4338086A1 (de) *	1993-11-08	1995-05-11	Dietl Hans	Cyclosporin(e) enthaltende pharmazeutische Zubereitung zur oralen Applikation sowie Verfahren zu ihrer Herstellung
FI100692B (fi) *	1994-05-24	1998-02-13	Leiras Oy	Menetelmä farmaseuttisten koostumusten valmistamiseksi, jolloin koostu mukset pohjautuvat mikroemulsiogeeleihin sekä uusia mikroemulsioihin p ohjautuvia geelejä
ES2094688B1 (es) *	1994-08-08	1997-08-01	Cusi Lab	Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion.
DE19537012A1 (de) *	1995-10-04	1997-04-10	Dietl Hans	Cyclosporin(e) enhaltende pharmazeutische Zubereitung zur oralen Applikation und Verfahren zu ihrer Herstellung
GB9601120D0 (en) *	1996-01-19	1996-03-20	Sandoz Ltd	Organic compounds
US5660858A (en) *	1996-04-03	1997-08-26	Research Triangle Pharmaceuticals	Cyclosporin emulsions

1998
- 1998-03-12 DE DE19810655A patent/DE19810655A1/de not_active Withdrawn
1999
- 1999-03-12 ES ES99104009T patent/ES2248935T3/es not_active Expired - Lifetime
- 1999-03-12 AT AT99104009T patent/ATE309816T1/de active
- 1999-03-12 DE DE59912782T patent/DE59912782D1/de not_active Expired - Lifetime
- 1999-03-12 EP EP99104009A patent/EP0945136B9/de not_active Expired - Lifetime
- 1999-03-12 DK DK99104009T patent/DK0945136T3/da active

Also Published As

Publication number	Publication date
ATE309816T1 (de)	2005-12-15
EP0945136B9 (de)	2006-07-26
ES2248935T3 (es)	2006-03-16
EP0945136A1 (de)	1999-09-29
DE19810655A1 (de)	1999-09-16
EP0945136B1 (de)	2005-11-16
DE59912782D1 (de)	2005-12-22

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