DK0951465T3 - Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf - Google Patents

Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf

Info

Publication number
DK0951465T3
DK0951465T3 DK97933680T DK97933680T DK0951465T3 DK 0951465 T3 DK0951465 T3 DK 0951465T3 DK 97933680 T DK97933680 T DK 97933680T DK 97933680 T DK97933680 T DK 97933680T DK 0951465 T3 DK0951465 T3 DK 0951465T3
Authority
DK
Denmark
Prior art keywords
alpha
preparation
amino acid
acid amides
therapeutic use
Prior art date
Application number
DK97933680T
Other languages
Danish (da)
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Maurizio Delcanale
Renato De Fanti
Elisabetta Armani
Gino Villetti
Claudio Pietra
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of DK0951465T3 publication Critical patent/DK0951465T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK97933680T 1996-07-23 1997-07-15 Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf DK0951465T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI001544A IT1283489B1 (it) 1996-07-23 1996-07-23 Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
PCT/EP1997/003773 WO1998003472A1 (en) 1996-07-23 1997-07-15 Alpha-amino acid amides, preparation thereof and the therapeutical use thereof

Publications (1)

Publication Number Publication Date
DK0951465T3 true DK0951465T3 (da) 2003-08-11

Family

ID=11374651

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97933680T DK0951465T3 (da) 1996-07-23 1997-07-15 Alpha-aminosyreamider, fremstilling deraf og den terapeutiske anvendelse deraf

Country Status (26)

Country Link
US (1) US6114391A (de)
EP (1) EP0951465B1 (de)
JP (1) JP4542208B2 (de)
CN (1) CN1211351C (de)
AR (1) AR007963A1 (de)
AT (1) ATE237584T1 (de)
AU (1) AU729176B2 (de)
CA (1) CA2261259C (de)
CZ (1) CZ295824B6 (de)
DE (1) DE69721052T2 (de)
DK (1) DK0951465T3 (de)
ES (1) ES2195158T3 (de)
HU (1) HU225623B1 (de)
ID (1) ID17999A (de)
IL (1) IL128020A (de)
IT (1) IT1283489B1 (de)
MY (1) MY118244A (de)
NO (1) NO326826B3 (de)
NZ (1) NZ333869A (de)
PT (1) PT951465E (de)
RU (1) RU2174511C2 (de)
SI (1) SI0951465T1 (de)
TR (1) TR199900087T2 (de)
TW (1) TW557291B (de)
WO (1) WO1998003472A1 (de)
ZA (1) ZA976479B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672746A (en) 1994-08-30 1997-09-30 American Biogenetic Sciences, Inc. Antiproliferative and neurotrophic molecules
MXPA00012808A (es) 1998-06-22 2002-04-24 American Biogenetic Sciences El uso de analogo de acido valproico para tratamiento y prevencion de migrana y enfermedad afectiva.
US20030035784A1 (en) 2001-03-05 2003-02-20 Kao Corporation Hair cosmetic, aminocarboxylic acid amide and method for producing the same
DE60122541T2 (de) * 2001-12-21 2007-09-13 Chiesi Farmaceutici S.P.A. 2-Indanylaminoderivate zur Therapie von chronischen, akuten oder entzündlichen Schmerzen
FR2843590B1 (fr) * 2002-08-14 2007-10-05 Prestwick Scient Capital Inc Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
US20040082543A1 (en) * 2002-10-29 2004-04-29 Pharmacia Corporation Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
EP1778623B1 (de) * 2004-08-03 2008-07-02 CHIESI FARMACEUTICI S.p.A. Derivate von 1-phenylalkancarbonsäuren zur behandlung von neurodegenerativen krankheiten
WO2014178083A1 (en) 2013-05-03 2014-11-06 Council Of Scientific & Industrial Research An improved synthesis of anti-parkinson agent
CN105646252A (zh) * 2016-02-25 2016-06-08 吉尔生化（上海）有限公司 一种丝氨酸酰胺盐酸盐的合成方法
PL3992177T3 (pl) * 2019-06-25 2024-08-26 Amtixbio Co., Ltd. Nowatorska pochodna kwasu aminoalkanowego, zawierająca w swojej strukturze ugrupowanie bifenylowe, oraz kompozycja farmaceutyczna o działaniu przeciwgrzybiczym, w skład której wchodzi ta pochodna
WO2022238507A1 (en) * 2021-05-11 2022-11-17 Awakn Ls Europe Holdings Limited Therapeutic aminoindane compounds and compositions

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3010599A1 (de) * 1979-03-22 1980-10-09 Continental Pharma Derivate von glycinamid, deren herstellung und verwendung
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
NL8800260A (nl) * 1988-02-04 1989-09-01 Stamicarbon Alpha-n-hydroxyaminozuren, amiden en andere derivaten daarvan.
DE68929368T2 (de) * 1988-03-16 2002-08-14 Eisai Co., Ltd. Cephemderivate und Verfahren zu ihrer Herstellung
IL94466A (en) * 1989-05-25 1995-01-24 Erba Carlo Spa Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5198547A (en) * 1992-03-16 1993-03-30 South Alabama Medical Science Foundation, Usa Process for N5-formylating tetrahydropteridines
GB9306886D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
GB9306899D0 (en) * 1993-04-01 1993-05-26 Erba Carlo Spa Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
US5332840A (en) * 1993-05-27 1994-07-26 Bristol-Myers Squibb Company Method for preparing a benzaldehyde intermediate
ES2173540T3 (es) * 1994-06-28 2002-10-16 Bayer Ag Derivados de aminoacidos y su empleo como agentes pesticidas.

Also Published As

Publication number Publication date
ATE237584T1 (de) 2003-05-15
EP0951465A1 (de) 1999-10-27
AR007963A1 (es) 1999-11-24
AU729176B2 (en) 2001-01-25
JP2001506577A (ja) 2001-05-22
SI0951465T1 (en) 2003-08-31
HUP9902992A3 (en) 2004-04-28
NO990300L (no) 1999-01-22
TW557291B (en) 2003-10-11
CN1211351C (zh) 2005-07-20
NO990300D0 (no) 1999-01-22
DE69721052D1 (de) 2003-05-22
AU3695297A (en) 1998-02-10
US6114391A (en) 2000-09-05
IL128020A (en) 2002-04-21
ZA976479B (en) 1998-03-02
HU225623B1 (en) 2007-05-02
IT1283489B1 (it) 1998-04-21
ID17999A (id) 1998-02-19
ES2195158T3 (es) 2003-12-01
NO326826B3 (no) 2010-06-07
JP4542208B2 (ja) 2010-09-08
CZ295824B6 (cs) 2005-11-16
EP0951465B1 (de) 2003-04-16
WO1998003472A1 (en) 1998-01-29
CZ18299A3 (cs) 1999-06-16
IL128020A0 (en) 1999-11-30
ITMI961544A0 (de) 1996-07-23
TR199900087T2 (xx) 1999-03-22
CA2261259C (en) 2006-10-03
NO326826B1 (no) 2009-02-23
CA2261259A1 (en) 1998-01-29
ITMI961544A1 (it) 1998-01-23
MY118244A (en) 2004-09-30
RU2174511C2 (ru) 2001-10-10
NZ333869A (en) 2000-05-26
CN1225625A (zh) 1999-08-11
PT951465E (pt) 2003-08-29
DE69721052T2 (de) 2004-02-05

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