ATE237584T1 - Alpha-aminosäureamide, ihre herstellung und ihre therapeutische anwendung - Google Patents

Alpha-aminosäureamide, ihre herstellung und ihre therapeutische anwendung

Info

Publication number: ATE237584T1
Authority: AT; Austria
Prior art keywords: alpha; production; amino acid; acid amides; therapeutic use
Prior art date: 1996-07-23

Application number

AT97933680T

Other languages

English (en)

Inventor

Paolo Chiesi

Paolo Ventura

Maurizio Delcanale

Renato De Fanti

Elisabetta Armani

Gino Villetti

Claudio Pietra

Original Assignee

Chiesi Farma Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-07-23

Filing date

1997-07-15

Publication date

2003-05-15

1997-07-15 Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa

2003-05-15 Application granted granted Critical

2003-05-15 Publication of ATE237584T1 publication Critical patent/ATE237584T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

AT97933680T 1996-07-23 1997-07-15 Alpha-aminosäureamide, ihre herstellung und ihre therapeutische anwendung ATE237584T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT96MI001544A IT1283489B1 (it)	1996-07-23	1996-07-23	Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
PCT/EP1997/003773 WO1998003472A1 (en)	1996-07-23	1997-07-15	Alpha-amino acid amides, preparation thereof and the therapeutical use thereof

Publications (1)

Publication Number	Publication Date
ATE237584T1 true ATE237584T1 (de)	2003-05-15

Family

ID=11374651

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97933680T ATE237584T1 (de)	1996-07-23	1997-07-15	Alpha-aminosäureamide, ihre herstellung und ihre therapeutische anwendung

Country Status (26)

Country	Link
US (1)	US6114391A (de)
EP (1)	EP0951465B1 (de)
JP (1)	JP4542208B2 (de)
CN (1)	CN1211351C (de)
AR (1)	AR007963A1 (de)
AT (1)	ATE237584T1 (de)
AU (1)	AU729176B2 (de)
CA (1)	CA2261259C (de)
CZ (1)	CZ295824B6 (de)
DE (1)	DE69721052T2 (de)
DK (1)	DK0951465T3 (de)
ES (1)	ES2195158T3 (de)
HU (1)	HU225623B1 (de)
ID (1)	ID17999A (de)
IL (1)	IL128020A (de)
IT (1)	IT1283489B1 (de)
MY (1)	MY118244A (de)
NO (1)	NO326826B3 (de)
NZ (1)	NZ333869A (de)
PT (1)	PT951465E (de)
RU (1)	RU2174511C2 (de)
SI (1)	SI0951465T1 (de)
TR (1)	TR199900087T2 (de)
TW (1)	TW557291B (de)
WO (1)	WO1998003472A1 (de)
ZA (1)	ZA976479B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5672746A (en)	1994-08-30	1997-09-30	American Biogenetic Sciences, Inc.	Antiproliferative and neurotrophic molecules
HUP0102456A3 (en)	1998-06-22	2003-07-28	American Biogenetic Sciences	The use of valproic acid analog for the treatment and prevention of migraine and affective illness
US20030035784A1 (en)	2001-03-05	2003-02-20	Kao Corporation	Hair cosmetic, aminocarboxylic acid amide and method for producing the same
DE60122541T2 (de) *	2001-12-21	2007-09-13	Chiesi Farmaceutici S.P.A.	2-Indanylaminoderivate zur Therapie von chronischen, akuten oder entzündlichen Schmerzen
FR2843590B1 (fr) *	2002-08-14	2007-10-05	Prestwick Scient Capital Inc	Derives de l'acide r(+)-2-amino-3-hydroxypropanoique a action glycinergique
US20040082543A1 (en) *	2002-10-29	2004-04-29	Pharmacia Corporation	Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
ES2309778T3 (es) *	2004-08-03	2008-12-16	Chiesi Farmaceutici S.P.A.	Derivados de acidos 1-fenilalcanocarboxilicos para el tratamiento de enfermedades neurodegenerativas.
US9475757B2 (en)	2013-05-03	2016-10-25	Council Of Scientific & Industrial Research	Synthesis of anti-Parkinson agent
CN105646252A (zh) *	2016-02-25	2016-06-08	吉尔生化（上海）有限公司	一种丝氨酸酰胺盐酸盐的合成方法
BR112021026076A2 (pt) *	2019-06-25	2022-03-29	Amtixbio Co Ltd	Composto derivado introduzindo o grupo bifenila no novo ácido aminoalcanoico e composição farmacêutica antifúngica compreendendo o mesmo
EP4337316A1 (de) *	2021-05-11	2024-03-20	Awakn Ls Europe Holdings Limited	Therapeutische aminoindanverbindungen und zusammensetzungen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3010599A1 (de) *	1979-03-22	1980-10-09	Continental Pharma	Derivate von glycinamid, deren herstellung und verwendung
DE3718317A1 (de) *	1986-12-10	1988-06-16	Bayer Ag	Substituierte basische 2-aminotetraline
NL8800260A (nl) *	1988-02-04	1989-09-01	Stamicarbon	Alpha-n-hydroxyaminozuren, amiden en andere derivaten daarvan.
DE68928174T2 (de) *	1988-03-16	1997-12-18	Eisai Co., Ltd., Tokio/Tokyo	Verfahren zur Herstellung von Cephemderivaten
IL94466A (en) *	1989-05-25	1995-01-24	Erba Carlo Spa	Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation
US5198547A (en) *	1992-03-16	1993-03-30	South Alabama Medical Science Foundation, Usa	Process for N5-formylating tetrahydropteridines
GB9306886D0 (en) *	1993-04-01	1993-05-26	Erba Carlo Spa	Substituted (arylakoxybenzyl) aminopropanamide derivatives and process for their preparation
GB9306899D0 (en) *	1993-04-01	1993-05-26	Erba Carlo Spa	Substituted (arylalkylaminobenzyl) aminopropionamide derivatives and process for their preparation
US5332840A (en) *	1993-05-27	1994-07-26	Bristol-Myers Squibb Company	Method for preparing a benzaldehyde intermediate
EP0767780B1 (de) *	1994-06-28	1999-12-15	Bayer Ag	Aminosäure-derivate und ihre verwendung als schädlingsbekämpfungsmittel

1996
- 1996-07-23 IT IT96MI001544A patent/IT1283489B1/it active IP Right Grant
1997
- 1997-07-15 NZ NZ333869A patent/NZ333869A/xx not_active IP Right Cessation
- 1997-07-15 US US09/147,553 patent/US6114391A/en not_active Expired - Fee Related
- 1997-07-15 WO PCT/EP1997/003773 patent/WO1998003472A1/en not_active Ceased
- 1997-07-15 PT PT97933680T patent/PT951465E/pt unknown
- 1997-07-15 CA CA002261259A patent/CA2261259C/en not_active Expired - Fee Related
- 1997-07-15 IL IL12802097A patent/IL128020A/en not_active IP Right Cessation
- 1997-07-15 DK DK97933680T patent/DK0951465T3/da active
- 1997-07-15 TR TR1999/00087T patent/TR199900087T2/xx unknown
- 1997-07-15 AU AU36952/97A patent/AU729176B2/en not_active Ceased
- 1997-07-15 AT AT97933680T patent/ATE237584T1/de not_active IP Right Cessation
- 1997-07-15 CN CNB971966044A patent/CN1211351C/zh not_active Expired - Fee Related
- 1997-07-15 RU RU99103681/04A patent/RU2174511C2/ru not_active IP Right Cessation
- 1997-07-15 JP JP50542498A patent/JP4542208B2/ja not_active Expired - Fee Related
- 1997-07-15 ES ES97933680T patent/ES2195158T3/es not_active Expired - Lifetime
- 1997-07-15 DE DE69721052T patent/DE69721052T2/de not_active Expired - Lifetime
- 1997-07-15 CZ CZ1999182A patent/CZ295824B6/cs not_active IP Right Cessation
- 1997-07-15 EP EP97933680A patent/EP0951465B1/de not_active Expired - Lifetime
- 1997-07-15 SI SI9730515T patent/SI0951465T1/xx unknown
- 1997-07-15 HU HU9902992A patent/HU225623B1/hu not_active IP Right Cessation
- 1997-07-21 ID IDP972516A patent/ID17999A/id unknown
- 1997-07-22 MY MYPI97003309A patent/MY118244A/en unknown
- 1997-07-22 AR ARP970103300A patent/AR007963A1/es active IP Right Grant
- 1997-07-22 ZA ZA9706479A patent/ZA976479B/xx unknown
- 1997-09-10 TW TW086113174A patent/TW557291B/zh active
1999
- 1999-01-22 NO NO19990300A patent/NO326826B3/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT951465E (pt)	2003-08-29
ITMI961544A0 (de)	1996-07-23
JP2001506577A (ja)	2001-05-22
IL128020A (en)	2002-04-21
EP0951465A1 (de)	1999-10-27
ID17999A (id)	1998-02-19
DE69721052D1 (de)	2003-05-22
EP0951465B1 (de)	2003-04-16
ES2195158T3 (es)	2003-12-01
SI0951465T1 (en)	2003-08-31
CZ295824B6 (cs)	2005-11-16
US6114391A (en)	2000-09-05
CZ18299A3 (cs)	1999-06-16
NO326826B3 (no)	2010-06-07
TR199900087T2 (xx)	1999-03-22
CA2261259C (en)	2006-10-03
CA2261259A1 (en)	1998-01-29
HU225623B1 (en)	2007-05-02
AU3695297A (en)	1998-02-10
AR007963A1 (es)	1999-11-24
MY118244A (en)	2004-09-30
HUP9902992A3 (en)	2004-04-28
WO1998003472A1 (en)	1998-01-29
IT1283489B1 (it)	1998-04-21
JP4542208B2 (ja)	2010-09-08
AU729176B2 (en)	2001-01-25
RU2174511C2 (ru)	2001-10-10
CN1211351C (zh)	2005-07-20
NO990300D0 (no)	1999-01-22
DE69721052T2 (de)	2004-02-05
NO326826B1 (no)	2009-02-23
ITMI961544A1 (it)	1998-01-23
ZA976479B (en)	1998-03-02
DK0951465T3 (da)	2003-08-11
IL128020A0 (en)	1999-11-30
TW557291B (en)	2003-10-11
NZ333869A (en)	2000-05-26
CN1225625A (zh)	1999-08-11
NO990300L (no)	1999-01-22

Legal Events

Date

Code

Title

Description

2003-11-15

UEP

Publication of translation of european patent specification

Ref document number: 0951465

Country of ref document: EP

2012-04-15

REN

Ceased due to non-payment of the annual fee

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