DK0953563T3 - Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor - Google Patents

Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor

Info

Publication number
DK0953563T3
DK0953563T3 DK97941241T DK97941241T DK0953563T3 DK 0953563 T3 DK0953563 T3 DK 0953563T3 DK 97941241 T DK97941241 T DK 97941241T DK 97941241 T DK97941241 T DK 97941241T DK 0953563 T3 DK0953563 T3 DK 0953563T3
Authority
DK
Denmark
Prior art keywords
preparing
well
novel intermediates
intermediates therefor
derivatives
Prior art date
Application number
DK97941241T
Other languages
English (en)
Inventor
Ryo Yamanishi
Masaru Ohgaki
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of DK0953563T3 publication Critical patent/DK0953563T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/12—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97941241T 1996-10-07 1997-09-24 Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor DK0953563T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28604796 1996-10-07
PCT/JP1997/003417 WO1998015523A1 (en) 1996-10-07 1997-09-24 Process for producing depsipeptide derivatives and novel intermediates therefor

Publications (1)

Publication Number Publication Date
DK0953563T3 true DK0953563T3 (da) 2003-07-28

Family

ID=17699289

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97941241T DK0953563T3 (da) 1996-10-07 1997-09-24 Fremgangsmåde til fremstilling af depsipeptidderivater samt hidtil ukendte intermediater derfor

Country Status (12)

Country Link
US (1) US6235875B1 (da)
EP (1) EP0953563B1 (da)
JP (1) JP4035852B2 (da)
CN (1) CN1205177C (da)
AT (1) ATE237583T1 (da)
BR (1) BR9712279A (da)
CA (1) CA2267376C (da)
DE (1) DE69721055T2 (da)
DK (1) DK0953563T3 (da)
ES (1) ES2191852T3 (da)
PT (1) PT953563E (da)
WO (1) WO1998015523A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100551651B1 (ko) * 1997-11-10 2006-02-13 아스텔라스세이야쿠 가부시키가이샤 뎁시펩티드 유도체의 신규 결정 및 그의 제조 방법
WO2006055621A2 (en) * 2004-11-17 2006-05-26 The University Of Chicago Histone deacetylase inhibitors and methods of use
RS62130B1 (sr) 2015-05-20 2021-08-31 Boehringer Ingelheim Animal Health Usa Inc Antihelmintička depsipeptidna jedinjenja
EP3397638B1 (en) 2015-12-28 2023-08-23 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
BR112019009977A2 (pt) 2016-11-16 2019-08-27 Boehringer Ingelheim Animal Health Usa Inc compostos depsipeptídicos anti-helmínticos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0634408T3 (da) 1992-03-17 2002-04-22 Fujisawa Pharmaceutical Co Depsipeptidderivater, fremstilling og anvendelse deraf
DE4317432A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
EP0718293B1 (en) 1993-09-06 2002-03-13 Fujisawa Pharmaceutical Co., Ltd. Cyclodepsipeptide compound
EP0872481B1 (en) 1995-06-30 2009-03-18 Astellas Pharma Inc. Depsipeptide derivative, process for production thereof, and novel intermediate therefor

Also Published As

Publication number Publication date
EP0953563A1 (en) 1999-11-03
DE69721055D1 (de) 2003-05-22
ATE237583T1 (de) 2003-05-15
BR9712279A (pt) 1999-08-31
CA2267376C (en) 2006-11-14
US6235875B1 (en) 2001-05-22
WO1998015523A1 (en) 1998-04-16
CA2267376A1 (en) 1998-04-16
CN1205177C (zh) 2005-06-08
PT953563E (pt) 2003-08-29
EP0953563B1 (en) 2003-04-16
ES2191852T3 (es) 2003-09-16
DE69721055T2 (de) 2004-02-19
CN1232446A (zh) 1999-10-20
EP0953563A4 (en) 2001-05-16
JP4035852B2 (ja) 2008-01-23

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