DK0956351T3 - Tumornekrosefaktorbeslægtet ligand - Google Patents

Tumornekrosefaktorbeslægtet ligand

Info

Publication number: DK0956351T3
Authority: DK; Denmark
Prior art keywords: necrosis factor; tumor necrosis; related ligand; trell; ligand
Prior art date: 1996-08-07

Application number

DK97935334T

Other languages

Danish (da)

English (en)

Inventor

Jeffrey L Browning

Yves Chicheportiche

Original Assignee

Biogen Idec Inc

Faculty Of Medicine Of The Uni

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-08-07

Filing date

1997-08-07

Publication date

2006-02-20

1997-08-07 Application filed by Biogen Idec Inc, Faculty Of Medicine Of The Uni filed Critical Biogen Idec Inc

2006-02-20 Application granted granted Critical

2006-02-20 Publication of DK0956351T3 publication Critical patent/DK0956351T3/da

Links

108060008682 Tumor Necrosis Factor Proteins 0.000 title abstract 4
102000003390 tumor necrosis factor Human genes 0.000 title abstract 4
239000003446 ligand Substances 0.000 title abstract 2
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Cell Biology (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
General Engineering & Computer Science (AREA)
Physics & Mathematics (AREA)
Urology & Nephrology (AREA)
Virology (AREA)
Biophysics (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Food Science & Technology (AREA)
Oncology (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Toxicology (AREA)
Analytical Chemistry (AREA)
General Physics & Mathematics (AREA)

DK97935334T 1996-08-07 1997-08-07 Tumornekrosefaktorbeslægtet ligand DK0956351T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date
US2354196P	1996-08-07	1996-08-07
US2851596P	1996-10-18	1996-10-18
US4082097P	1997-03-18	1997-03-18

Publications (1)

Publication Number	Publication Date
DK0956351T3 true DK0956351T3 (da)	2006-02-20

Family

ID=27362110

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97935334T DK0956351T3 (da)	1996-08-07	1997-08-07	Tumornekrosefaktorbeslægtet ligand

Country Status (25)

Country	Link
EP (2)	EP1591530B8 (de)
JP (3)	JP4161084B2 (de)
KR (1)	KR100543730B1 (de)
CN (2)	CN101024831A (de)
AT (1)	ATE307204T1 (de)
AU (1)	AU736289B2 (de)
BG (1)	BG64779B1 (de)
BR (1)	BR9711046A (de)
CA (1)	CA2262756C (de)
CZ (1)	CZ297387B6 (de)
DE (1)	DE69734397T2 (de)
DK (1)	DK0956351T3 (de)
EA (1)	EA003187B1 (de)
EE (1)	EE05276B1 (de)
ES (1)	ES2251737T3 (de)
HU (1)	HU226787B1 (de)
IL (1)	IL128407A (de)
IS (1)	IS2606B (de)
NO (2)	NO326967B1 (de)
NZ (1)	NZ334107A (de)
PL (1)	PL188102B1 (de)
SI (1)	SI0956351T1 (de)
SK (1)	SK288012B6 (de)
TR (1)	TR199900903T2 (de)
WO (1)	WO1998005783A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU9376498A (en) *	1997-09-05	1999-03-22	University Of Washington	Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
AU749948B2 (en) *	1997-10-10	2002-07-04	Genentech Inc.	APO-3 ligand
DE19829550C1 (de) *	1998-07-02	2000-01-27	Bosch Gmbh Robert	Vorrichtung zum Verbinden von Bauteilen
EA004590B1 (ru) *	1999-01-15	2004-06-24	Байоджен, Инк.	Способ блокировки развития, или снижения тяжести, или проявлений заболевания "трасплантат против хозяина"
AU784504B2 (en) *	1999-11-19	2006-04-13	Thomas V. Tittle	TR3-specific binding agents and methods for their use
US6994976B1 (en)	1999-11-19	2006-02-07	Tittle Thomas V	Tr3-specific binding agents and methods for their use
CA2394015C (en) *	1999-12-20	2013-11-05	Immunex Corporation	Tweak receptor
US6727225B2 (en)	1999-12-20	2004-04-27	Immunex Corporation	TWEAK receptor
US7495086B2 (en)	1999-12-20	2009-02-24	Immunex Corporation	TWEAK receptor
US6943146B2 (en)	2000-05-08	2005-09-13	Biogen Idec Ma Inc.	Method for promoting neovascularization
US7208151B2 (en)	2001-09-12	2007-04-24	Biogen Idec Ma Inc.	Tweak receptor agonists as anti-angiogenic agents
AU2003224950B2 (en)	2002-04-09	2006-09-14	Biogen Ma Inc.	Methods for treating tweak-related conditions
EP2311867A1 (de) *	2002-10-29	2011-04-20	Anaphore, Inc.	Trimeres Bindungsprotein für trimeres Zytokin
AU2006214179A1 (en)	2005-02-17	2006-08-24	Biogen Idec Ma Inc.	Treating neurological disorders
WO2006122187A2 (en)	2005-05-10	2006-11-16	Biogen Idec Ma Inc.	Treating and evaluating inflammatory disorders
WO2006130374A2 (en)	2005-05-27	2006-12-07	Biogen Idec Ma Inc.	Tweak binding antibodies
WO2006138219A2 (en)	2005-06-13	2006-12-28	Biogen Idec Ma Inc.	Methods of diagnosis / prognosis of inflammatory conditions
US8093006B2 (en)	2009-04-02	2012-01-10	Hoffmann-La Roche Inc.	Antibodies against human tweak and uses thereof
BR112013007293A2 (pt)	2010-10-05	2016-06-14	Hoffmann La Roche	anticorpos contra a tweak de seres humanos e suas utilizações
KR101674784B1 (ko)	2012-04-05	2016-11-09	에프. 호프만-라 로슈 아게	인간 tweak 및 인간 il17에 대한 이중특이적 항체 및 이의 용도
CN110023499A (zh) *	2016-10-24	2019-07-16	拜欧亿思有限公司	肿瘤坏死因子-α(TNF-α)结合适配体及其治疗用途
US11447778B2 (en) *	2018-04-20	2022-09-20	Academia Sinica	TNF-targeting aptamers and uses thereof for treatment or diagnosing TNF-related inflammatory diseases
CA3214688A1 (en)	2021-04-08	2022-10-13	Andrzej KROLEWSKI	Methods of diagnosing and predicting renal decline

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4816567A (en)	1983-04-08	1989-03-28	Genentech, Inc.	Recombinant immunoglobin preparations
US5176996A (en)	1988-12-20	1993-01-05	Baylor College Of Medicine	Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
US5256775A (en)	1989-06-05	1993-10-26	Gilead Sciences, Inc.	Exonuclease-resistant oligonucleotides
IE902820A1 (en)	1989-08-07	1991-02-27	Merck & Co Inc	Peptide inhibitors of human papilloma virus protein binding¹to retinoblastoma gene proteins
US5264564A (en)	1989-10-24	1993-11-23	Gilead Sciences	Oligonucleotide analogs with novel linkages
JPH05310784A (ja)	1991-09-04	1993-11-22	Merck & Co Inc	ヒト乳頭腫ウイルスタンパク質と網膜芽細胞腫遺伝子タンパク質との結合のペプチド阻害剤

1997
- 1997-08-07 CA CA2262756A patent/CA2262756C/en not_active Expired - Lifetime
- 1997-08-07 SI SI9730718T patent/SI0956351T1/sl unknown
- 1997-08-07 TR TR1999/00903T patent/TR199900903T2/xx unknown
- 1997-08-07 JP JP50823998A patent/JP4161084B2/ja not_active Expired - Lifetime
- 1997-08-07 CZ CZ0040399A patent/CZ297387B6/cs not_active IP Right Cessation
- 1997-08-07 AU AU38294/97A patent/AU736289B2/en not_active Ceased
- 1997-08-07 SK SK157-99A patent/SK288012B6/sk not_active IP Right Cessation
- 1997-08-07 EA EA199900187A patent/EA003187B1/ru not_active IP Right Cessation
- 1997-08-07 CN CNA2007100059560A patent/CN101024831A/zh active Pending
- 1997-08-07 HU HU9903921A patent/HU226787B1/hu unknown
- 1997-08-07 EP EP05011540.1A patent/EP1591530B8/de not_active Expired - Lifetime
- 1997-08-07 EP EP97935334A patent/EP0956351B1/de not_active Expired - Lifetime
- 1997-08-07 WO PCT/US1997/013945 patent/WO1998005783A1/en not_active Ceased
- 1997-08-07 DK DK97935334T patent/DK0956351T3/da active
- 1997-08-07 NZ NZ334107A patent/NZ334107A/en not_active IP Right Cessation
- 1997-08-07 BR BR9711046-9A patent/BR9711046A/pt not_active Application Discontinuation
- 1997-08-07 EE EEP199900043A patent/EE05276B1/xx unknown
- 1997-08-07 CN CNB971984018A patent/CN1308451C/zh not_active Expired - Lifetime
- 1997-08-07 AT AT97935334T patent/ATE307204T1/de active
- 1997-08-07 IL IL128407A patent/IL128407A/en not_active IP Right Cessation
- 1997-08-07 KR KR1019997001045A patent/KR100543730B1/ko not_active Expired - Lifetime
- 1997-08-07 DE DE69734397T patent/DE69734397T2/de not_active Expired - Lifetime
- 1997-08-07 ES ES97935334T patent/ES2251737T3/es not_active Expired - Lifetime
- 1997-08-07 PL PL97331583A patent/PL188102B1/pl unknown
1999
- 1999-02-05 IS IS4967A patent/IS2606B/is unknown
- 1999-02-05 NO NO990550A patent/NO326967B1/no not_active IP Right Cessation
- 1999-02-11 BG BG103169A patent/BG64779B1/bg unknown
2007
- 2007-02-07 JP JP2007028621A patent/JP4411330B2/ja not_active Expired - Lifetime
2008
- 2008-11-21 NO NO20084906A patent/NO20084906L/no not_active Application Discontinuation
2009
- 2009-03-27 JP JP2009080644A patent/JP2009183294A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
CZ297387B6 (cs)	2006-11-15
NZ334107A (en)	2000-06-23
JP2009183294A (ja)	2009-08-20
JP4411330B2 (ja)	2010-02-10
EP1591530B1 (de)	2015-02-25
IS2606B (is)	2010-04-15
EE9900043A (et)	1999-08-16
CZ40399A3 (cs)	1999-08-11
EP0956351B1 (de)	2005-10-19
IL128407A (en)	2007-07-24
EA003187B1 (ru)	2003-02-27
TR199900903T2 (xx)	1999-06-21
ES2251737T3 (es)	2006-05-01
HU226787B1 (en)	2009-10-28
BR9711046A (pt)	2000-01-11
NO326967B1 (no)	2009-03-23
SK288012B6 (sk)	2012-10-02
EP1591530B8 (de)	2015-04-22
CA2262756A1 (en)	1998-02-12
WO1998005783A1 (en)	1998-02-12
CN101024831A (zh)	2007-08-29
EP1591530A3 (de)	2009-04-08
HK1025994A1 (en)	2000-12-01
BG64779B1 (bg)	2006-03-31
NO990550D0 (no)	1999-02-05
EA199900187A1 (ru)	1999-08-26
KR100543730B1 (ko)	2006-01-23
CA2262756C (en)	2012-06-12
AU736289B2 (en)	2001-07-26
DE69734397D1 (de)	2006-03-02
ATE307204T1 (de)	2005-11-15
NO990550L (no)	1999-04-06
BG103169A (en)	2000-06-30
PL331583A1 (en)	1999-07-19
SI0956351T1 (sl)	2006-02-28
JP4161084B2 (ja)	2008-10-08
EE05276B1 (et)	2010-02-15
CN1232503A (zh)	1999-10-20
IS4967A (is)	1999-02-05
IL128407A0 (en)	2000-01-31
DE69734397T2 (de)	2006-07-06
CN1308451C (zh)	2007-04-04
JP2001505407A (ja)	2001-04-24
HUP9903921A3 (en)	2000-08-28
NO20084906L (no)	1999-04-06
HUP9903921A2 (hu)	2000-03-28
SK15799A3 (en)	2000-03-13
EP1591530A2 (de)	2005-11-02
EP0956351A1 (de)	1999-11-17
AU3829497A (en)	1998-02-25
KR20000029877A (ko)	2000-05-25
JP2007204480A (ja)	2007-08-16
PL188102B1 (pl)	2004-12-31

Publication	Publication Date	Title
DE69734397D1 (de)	2006-03-02	Tumor-nekrose-faktor ähnliches ligand
WO1999012965A3 (en)	1999-06-03	April- a novel protein with growth effects
EA200000311A1 (ru)	2000-10-30	Новый белок иммунной системы - кау
FI891527L (fi)	1989-10-02	Neutrala foerstoftade filmer bestaoende av metallegeringsoxider.
FI941459A7 (fi)	1994-09-30	Tuumorinekroositekijän muteiineja
DE69202006D1 (de)	1995-05-18	Angetriebener Trokar.
FI872393A7 (fi)	1987-11-30	Tuumorin nekroositekijäformulaatio.
DE3888146D1 (de)	1994-04-07	Modifizierte Polytetrafluoräthylenharze und damit hergestellte Zusammensetzungen.
EP0601695A3 (de)	1995-02-15	Operationstisch.
FI902343L (fi)	1991-11-11	Foerfarande foer bestaellning av hiss i hissgrupp.
DE68901930D1 (de)	1992-08-06	Luefter.
DE58909374D1 (de)	1995-09-07	Lüfter.
FR2707297B1 (fr)	1995-08-25	Mélange silicone autoémulsifiable.
FI904357A0 (fi)	1990-09-04	Foerfarande foer aktivering av protein c.
DE3873728D1 (de)	1992-09-17	Luefter.
DE69109911D1 (de)	1995-06-29	Fluoreszierende Polymere und Bestandteile dafür.
FI904554L (fi)	1992-03-15	Foerfarande foer montering av plandoerrar foer hiss.
DE68901973D1 (de)	1992-08-13	Luefter.
FI920845A0 (fi)	1992-02-26	Farmaceutiska kompositioner innehaollande interleukin-2.
FI901335L (fi)	1991-09-17	Foerfarande foer reglering av hastighetsboervaerde av en spaenningsreglerad kortsluten vaexelstroemsmotor i en hiss.
FI904766A0 (fi)	1990-09-27	Foerfarande foer detektering av protein.
ES1020875Y (es)	1993-03-01	Futbolin.
DE59204126D1 (de)	1995-11-30	Gebläse.
ATE102224T1 (de)	1994-03-15	Modifizierte polytetrafluoraethylenharze und damit hergestellte zusammensetzungen.
FI911226A0 (fi)	1991-03-12	En serie av leksaksbyggnadsplattor.