DK0983363T3 - Phosphatidyl-3,4,5-triphosphat-afhængig proteinkinase - Google Patents

Phosphatidyl-3,4,5-triphosphat-afhængig proteinkinase

Info

Publication number
DK0983363T3
DK0983363T3 DK98909642T DK98909642T DK0983363T3 DK 0983363 T3 DK0983363 T3 DK 0983363T3 DK 98909642 T DK98909642 T DK 98909642T DK 98909642 T DK98909642 T DK 98909642T DK 0983363 T3 DK0983363 T3 DK 0983363T3
Authority
DK
Denmark
Prior art keywords
protein kinase
dependent protein
phosphatidyl
triphosphate
isolated polynucleotides
Prior art date
Application number
DK98909642T
Other languages
English (en)
Inventor
Dario Renato Alessi
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9705462.1A external-priority patent/GB9705462D0/en
Priority claimed from GBGB9712826.8A external-priority patent/GB9712826D0/en
Priority claimed from GBGB9717253.0A external-priority patent/GB9717253D0/en
Priority claimed from US08/943,667 external-priority patent/US6734001B1/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of DK0983363T3 publication Critical patent/DK0983363T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK98909642T 1997-03-17 1998-03-16 Phosphatidyl-3,4,5-triphosphat-afhængig proteinkinase DK0983363T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9705462.1A GB9705462D0 (en) 1997-03-17 1997-03-17 Enzyme
GBGB9712826.8A GB9712826D0 (en) 1997-06-19 1997-06-19 Enyzme
GBGB9717253.0A GB9717253D0 (en) 1997-08-15 1997-08-15 Enzyme
US08/943,667 US6734001B1 (en) 1997-03-17 1997-10-03 3-phosphoinositide-dependent protein kinase

Publications (1)

Publication Number Publication Date
DK0983363T3 true DK0983363T3 (da) 2006-03-06

Family

ID=27451614

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98909642T DK0983363T3 (da) 1997-03-17 1998-03-16 Phosphatidyl-3,4,5-triphosphat-afhængig proteinkinase

Country Status (10)

Country Link
US (3) US7205390B2 (da)
EP (1) EP0983363B1 (da)
JP (2) JP3795535B2 (da)
AT (1) ATE310825T1 (da)
AU (1) AU734754B2 (da)
CA (1) CA2284119C (da)
DE (1) DE69832484T2 (da)
DK (1) DK0983363T3 (da)
ES (1) ES2256931T3 (da)
WO (1) WO1998041638A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3795535B2 (ja) 1997-03-17 2006-07-12 メディカル リサーチ カウンセル ホスファチジル3,4,5−トリホスフェイト依存性プロテインキナーゼ
EP1017826A2 (en) * 1997-09-26 2000-07-12 Onyx Pharmaceuticals Compositions and methods for identifying pkb kinase inhibitors
US6682920B1 (en) * 1997-09-26 2004-01-27 Onyx Pharmaceuticals, Inc. Compositions and methods for identifying PKB kinase inhibitors
AU3591799A (en) * 1998-04-27 1999-11-16 University Health Network Gene screening methods and related assays
CA2355362A1 (en) * 1998-12-14 2000-06-22 Medical Research Council Screening methods based on the use of protein kinases
GB9906245D0 (en) * 1999-03-19 1999-05-12 Medical Res Council Enzyme
WO2001044497A2 (en) * 1999-12-02 2001-06-21 University Of Dundee Protein kinase regulation
GB0213186D0 (en) * 2002-06-08 2002-07-17 Univ Dundee Methods
US9580750B2 (en) * 2005-05-23 2017-02-28 The Johns Hopkins University P13K pathway mutations in cancer
EP2094837B1 (en) * 2006-12-14 2012-04-25 Medical Research Council Use of pi3k, m-tor and akt inhibitors to induce foxp3 expression and generate regulatory t cells
EP2182058A1 (en) 2008-10-17 2010-05-05 Universität des Saarlandes High resolution complex structure and allosteric effects of low molecular weight activators on the protein kinase PDK1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996012024A1 (de) * 1994-10-13 1996-04-25 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., Berlin Klonierung, expression und charakterisierung einer neuen form der phosphatidylinositol-3-kinase
JP3795535B2 (ja) 1997-03-17 2006-07-12 メディカル リサーチ カウンセル ホスファチジル3,4,5−トリホスフェイト依存性プロテインキナーゼ
US6734001B1 (en) 1997-03-17 2004-05-11 Medical Research Council 3-phosphoinositide-dependent protein kinase
EP1017826A2 (en) 1997-09-26 2000-07-12 Onyx Pharmaceuticals Compositions and methods for identifying pkb kinase inhibitors
US6682920B1 (en) * 1997-09-26 2004-01-27 Onyx Pharmaceuticals, Inc. Compositions and methods for identifying PKB kinase inhibitors

Also Published As

Publication number Publication date
AU6412498A (en) 1998-10-12
EP0983363B1 (en) 2005-11-23
ES2256931T3 (es) 2006-07-16
JP2001516218A (ja) 2001-09-25
JP2005323611A (ja) 2005-11-24
DE69832484T2 (de) 2006-08-10
US7344870B2 (en) 2008-03-18
WO1998041638A1 (en) 1998-09-24
US20030108971A1 (en) 2003-06-12
US20100093027A1 (en) 2010-04-15
CA2284119C (en) 2010-06-15
JP3795535B2 (ja) 2006-07-12
US7842488B2 (en) 2010-11-30
DE69832484D1 (en) 2005-12-29
US7205390B2 (en) 2007-04-17
AU734754B2 (en) 2001-06-21
EP0983363A1 (en) 2000-03-08
CA2284119A1 (en) 1998-09-24
US20050032185A1 (en) 2005-02-10
ATE310825T1 (de) 2005-12-15

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