ATE295423T1 - Phosphodiesterase 8 - Google Patents

Phosphodiesterase 8

Info

Publication number
ATE295423T1
ATE295423T1 AT98953651T AT98953651T ATE295423T1 AT E295423 T1 ATE295423 T1 AT E295423T1 AT 98953651 T AT98953651 T AT 98953651T AT 98953651 T AT98953651 T AT 98953651T AT E295423 T1 ATE295423 T1 AT E295423T1
Authority
AT
Austria
Prior art keywords
polypeptides
polynucleotides
pde8
expression constructs
phosphodiesterase
Prior art date
Application number
AT98953651T
Other languages
English (en)
Inventor
Kate Loughney
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25491965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE295423(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE295423T1 publication Critical patent/ATE295423T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cereal-Derived Products (AREA)
AT98953651T 1997-10-16 1998-10-16 Phosphodiesterase 8 ATE295423T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/951,648 US5932465A (en) 1997-10-16 1997-10-16 Phosphodiesterase 8A
PCT/US1998/021956 WO1999019495A1 (en) 1997-10-16 1998-10-16 Phosphodiesterase 8a

Publications (1)

Publication Number Publication Date
ATE295423T1 true ATE295423T1 (de) 2005-05-15

Family

ID=25491965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98953651T ATE295423T1 (de) 1997-10-16 1998-10-16 Phosphodiesterase 8

Country Status (14)

Country Link
US (4) US5932465A (de)
EP (2) EP0944725B1 (de)
JP (1) JP2001512327A (de)
CN (2) CN1800399A (de)
AT (1) ATE295423T1 (de)
AU (1) AU1097499A (de)
BR (1) BR9806318A (de)
CA (1) CA2275135A1 (de)
DE (1) DE69830143T2 (de)
ES (1) ES2245485T3 (de)
IL (3) IL130287A0 (de)
NO (1) NO992916L (de)
RU (2) RU2272841C2 (de)
WO (1) WO1999019495A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2238283C (en) * 1997-05-30 2002-08-20 Cell Pathways, Inc. Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
EP0967284A1 (de) * 1998-05-28 1999-12-29 Pfizer Limited Phosphodiesterasen
US6130053A (en) * 1999-08-03 2000-10-10 Cell Pathways, Inc. Method for selecting compounds for inhibition of neoplastic lesions
GB9922125D0 (en) 1999-09-17 1999-11-17 Pfizer Ltd Phosphodiesterase enzymes
US6673564B2 (en) * 1999-10-18 2004-01-06 Millennium Pharmaceuticals, Inc. Methods for using 22045, a human cyclic nucleotide phosphodiesterase
CN1297049A (zh) * 1999-11-23 2001-05-30 上海博容基因开发有限公司 一种新的多肽——人环磷酸鸟嘌呤抑制的磷酸二酯酶17和编码这种多肽的多核苷酸
US6555547B1 (en) 2000-02-28 2003-04-29 Cell Pathways, Inc. Method for treating a patient with neoplasia by treatment with a vinca alkaloid derivative
US6569638B1 (en) 2000-03-03 2003-05-27 Cell Pathways, Inc Method for screening compounds for the treatment of neoplasia
CN1312381A (zh) * 2000-03-07 2001-09-12 上海博德基因开发有限公司 一种新的多肽——人环腺苷酸磷酸二脂酶13和编码这种多肽的多核苷酸
DE60130565D1 (de) * 2000-09-12 2007-10-31 Univ Bern Pde8a und seine verwendung
EP1414841B1 (de) * 2001-07-10 2012-11-14 Lakewood-Amedex, Inc Oligonukleotidhaltige pharmakologische zusammensetzungen und deren verwendung
WO2004042388A2 (en) * 2002-11-08 2004-05-21 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human phosphodiesterase 8a (pde8a)
WO2005089505A2 (en) * 2004-03-19 2005-09-29 Yale University Detection, isolation and uses of renalase (monoamine oxidase c)
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
AU2006315299A1 (en) 2005-11-21 2007-05-24 Yale University Methods of regulating renalase (Monoamine Oxidase C)
JP5580192B2 (ja) * 2007-03-27 2014-08-27 オメロス コーポレーション 運動障害の処置のためのｐｄｅ７インヒビターの使用
ES2700877T3 (es) * 2009-05-12 2019-02-19 Koninklijke Philips Nv Fosfodiesterasa 4D7 como marcador de cáncer de próstata
RU2601154C2 (ru) * 2011-03-11 2016-10-27 Синаджива Байофарма Корп Гибридные белки npp1
RU2760943C2 (ru) * 2011-09-15 2021-12-01 Алексион Фармасьютикалз, Инк. Гибридные белки NPP1
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
US12134790B2 (en) 2017-09-27 2024-11-05 Inozyme Pharma, Inc. Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (NPP1)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2151463T5 (es) * 1989-12-22 2012-10-29 Merck Serono Sa Constructos de ADN para la activación y la modificación de la expresión de genes endógenos
AU664847B2 (en) * 1991-05-15 1995-12-07 Cell Genesys, Inc. Genomic modifications with homologous DNA targeting
TW402639B (en) * 1992-12-03 2000-08-21 Transkaryotic Therapies Inc Protein production and protein delivery
US5798246A (en) * 1996-03-25 1998-08-25 Incyte Pharmaceuticals, Inc. Cyclic nucleotide phosphodiesterase

Also Published As

Publication number Publication date
EP0944725A1 (de) 1999-09-29
DE69830143D1 (en) 2005-06-16
CN1248291A (zh) 2000-03-22
US20030215919A1 (en) 2003-11-20
EP0944725B1 (de) 2005-05-11
US5932465A (en) 1999-08-03
CN1800399A (zh) 2006-07-12
IL175698A0 (en) 2008-02-09
NO992916L (no) 1999-08-06
WO1999019495A1 (en) 1999-04-22
BR9806318A (pt) 2000-03-14
EP1571216A3 (de) 2006-04-26
IL130287A0 (en) 2000-06-01
NO992916D0 (no) 1999-06-15
EP1571216A2 (de) 2005-09-07
AU1097499A (en) 1999-05-03
JP2001512327A (ja) 2001-08-21
RU2005136013A (ru) 2007-05-27
RU2272841C2 (ru) 2006-03-27
US6566087B1 (en) 2003-05-20
IL130287A (en) 2006-08-20
ES2245485T3 (es) 2006-01-01
CN1229499C (zh) 2005-11-30
CA2275135A1 (en) 1999-04-22
US6133007A (en) 2000-10-17
DE69830143T2 (de) 2006-03-02

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