DK1003458T3 - fprøvning af leverfunktion - Google Patents

fprøvning af leverfunktion

Info

Publication number
DK1003458T3
DK1003458T3 DK98936568T DK98936568T DK1003458T3 DK 1003458 T3 DK1003458 T3 DK 1003458T3 DK 98936568 T DK98936568 T DK 98936568T DK 98936568 T DK98936568 T DK 98936568T DK 1003458 T3 DK1003458 T3 DK 1003458T3
Authority
DK
Denmark
Prior art keywords
liver function
function test
patient
acid derivative
bile acid
Prior art date
Application number
DK98936568T
Other languages
English (en)
Inventor
Charles Oswald Mills
Original Assignee
Norgine Europe Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norgine Europe Bv filed Critical Norgine Europe Bv
Application granted granted Critical
Publication of DK1003458T3 publication Critical patent/DK1003458T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0041—Xanthene dyes, used in vivo, e.g. administered to a mice, e.g. rhodamines, rose Bengal
    • A61K49/0043—Fluorescein, used in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/005—Fluorescence in vivo characterised by the carrier molecule carrying the fluorescent agent
    • A61K49/0052—Small organic molecules
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/583—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with non-fluorescent dye label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/728—Bilirubin; including biliverdin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/145555—Hetero-N
    • Y10T436/146666—Bile pigment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Pyrane Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
DK98936568T 1997-08-12 1998-08-03 fprøvning af leverfunktion DK1003458T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9716962.7A GB9716962D0 (en) 1997-08-12 1997-08-12 Liver function test
PCT/GB1998/002322 WO1999007325A1 (en) 1997-08-12 1998-08-03 Liver function test

Publications (1)

Publication Number Publication Date
DK1003458T3 true DK1003458T3 (da) 2002-11-18

Family

ID=10817313

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98936568T DK1003458T3 (da) 1997-08-12 1998-08-03 fprøvning af leverfunktion

Country Status (14)

Country Link
US (1) US6030841A (da)
EP (1) EP1003458B1 (da)
JP (1) JP3477616B2 (da)
KR (1) KR100444564B1 (da)
CN (2) CN1991367A (da)
AT (1) ATE226415T1 (da)
AU (1) AU732900B2 (da)
CA (1) CA2300097C (da)
DE (1) DE69808930T2 (da)
DK (1) DK1003458T3 (da)
ES (1) ES2183399T3 (da)
GB (1) GB9716962D0 (da)
PT (1) PT1003458E (da)
WO (1) WO1999007325A1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2220105T3 (es) * 1998-07-01 2004-12-01 Andreas Prof. Dr. Med. Hoeft Determinacion de la funcion hepatica mediante una tasa de desaparacion del plasma.
SE521014C2 (sv) 1999-02-04 2003-09-23 Prostalund Operations Ab Anordning för värmebehandling av prostata
SE521275C2 (sv) 1999-05-07 2003-10-14 Prostalund Operations Ab Anordning vid värmebehandling av kroppsvävnad
GB0017822D0 (en) * 2000-07-21 2000-09-06 Norgine Europe Bv Pharmaceutically active compound
US6868290B2 (en) 2001-11-05 2005-03-15 Prostalund Operations Ab Thermotherapy catheter and method of prostate thermotherapy with improved guide and heat confinement
WO2003045315A2 (en) * 2001-11-26 2003-06-05 Cortex Pharmaceuticals, Inc. Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses
CN100502763C (zh) * 2002-12-09 2009-06-24 味之素株式会社 生物体状态信息处理装置和其方法、以及生物体状态信息管理系统
GB0808777D0 (en) * 2008-05-15 2008-06-18 Norgine Bv Prognostic method
GB2467902A (en) 2009-02-12 2010-08-18 Norgine Bv Preparation of Cholyl-L-lysine from N-E-CBZ-cholyl-L-lysine
JP2010261871A (ja) * 2009-05-08 2010-11-18 Geno Membrane:Kk 標識化胆汁酸
CN102488525B (zh) * 2011-12-14 2014-04-16 吉林大学 一种去血氧波动干扰的肝储备功能检测装置
WO2014029756A1 (en) * 2012-08-20 2014-02-27 Novassay Sa Cholyl-l-lysyl-fluorescein assay
CN104688234A (zh) * 2015-03-17 2015-06-10 吉林大学 一种icg色素浓度谱的无创、抗扰动检测方法
KR101882485B1 (ko) 2016-06-30 2018-07-27 강경찬 체내 간기능효소 및 지질 함유량 측정방법
CN106749473B (zh) * 2017-01-13 2018-08-17 常德云港生物科技有限公司 一种从鸭胆汁中提取鹅去氧胆酸和别胆酸的方法
CN116183565A (zh) * 2022-12-09 2023-05-30 青岛大学 快速检测小分子化合物与fxr受体结合能力的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4264514A (en) * 1977-11-14 1981-04-28 Abbott Laboratories Method and reagents for measuring the level of conjugated bile acids
US4848349A (en) * 1987-04-29 1989-07-18 Sherman Igor A Substance and method for measuring hepatic blood flow
JPH0657216B2 (ja) * 1988-09-14 1994-08-03 住友電気工業株式会社 肝機能検査装置
GB9517043D0 (en) * 1995-08-19 1995-10-25 Univ Birmingham The use of bile acid derivatives

Also Published As

Publication number Publication date
AU8553098A (en) 1999-03-01
CN1275060A (zh) 2000-11-29
DE69808930T2 (de) 2003-08-07
KR100444564B1 (ko) 2004-08-16
PT1003458E (pt) 2003-01-31
ATE226415T1 (de) 2002-11-15
JP2001513584A (ja) 2001-09-04
AU732900B2 (en) 2001-05-03
EP1003458A2 (en) 2000-05-31
US6030841A (en) 2000-02-29
CA2300097C (en) 2004-10-12
EP1003458B1 (en) 2002-10-23
KR20010022806A (ko) 2001-03-26
CA2300097A1 (en) 1999-02-18
HK1024413A1 (en) 2000-10-13
WO1999007325A8 (en) 1999-03-25
CN1991367A (zh) 2007-07-04
WO1999007325A1 (en) 1999-02-18
DE69808930D1 (de) 2002-11-28
ES2183399T3 (es) 2003-03-16
JP3477616B2 (ja) 2003-12-10
GB9716962D0 (en) 1997-10-15

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