DK1003873T3 - Öget produktion af proteiner i grampositive mikroorganismer - Google Patents
Öget produktion af proteiner i grampositive mikroorganismerInfo
- Publication number
- DK1003873T3 DK1003873T3 DK98935747T DK98935747T DK1003873T3 DK 1003873 T3 DK1003873 T3 DK 1003873T3 DK 98935747 T DK98935747 T DK 98935747T DK 98935747 T DK98935747 T DK 98935747T DK 1003873 T3 DK1003873 T3 DK 1003873T3
- Authority
- DK
- Denmark
- Prior art keywords
- gram
- positive microorganisms
- proteins
- increased production
- present
- Prior art date
Links
- 244000005700 microbiome Species 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 230000028327 secretion Effects 0.000 abstract 3
- 244000063299 Bacillus subtilis Species 0.000 abstract 1
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97305286 | 1997-07-16 | ||
| EP97305344 | 1997-07-17 | ||
| EP98935747A EP1003873B1 (en) | 1997-07-16 | 1998-07-15 | Increasing production of proteins in gram-positive microorganisms |
| PCT/US1998/014786 WO1999004007A1 (en) | 1997-07-16 | 1998-07-15 | Increasing production of proteins in gram-positive microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1003873T3 true DK1003873T3 (da) | 2005-08-01 |
Family
ID=26147520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98935747T DK1003873T3 (da) | 1997-07-16 | 1998-07-15 | Öget produktion af proteiner i grampositive mikroorganismer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6258563B1 (da) |
| EP (1) | EP1003873B1 (da) |
| JP (1) | JP2001510047A (da) |
| AT (1) | ATE292683T1 (da) |
| AU (1) | AU8493198A (da) |
| CA (1) | CA2296689C (da) |
| DE (1) | DE69829670T2 (da) |
| DK (1) | DK1003873T3 (da) |
| WO (1) | WO1999004007A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6630328B2 (en) * | 1909-07-15 | 2003-10-07 | Genencor International, Inc. | Increasing production of proteins in gram-positive microorganisms |
| WO2005056799A1 (en) | 2003-12-10 | 2005-06-23 | Novozymes A/S | A cell with improved secretion mediated by mrga protein or homologue |
| CN101278044A (zh) * | 2005-06-24 | 2008-10-01 | 诺维信公司 | 适用于制备重组多肽的突变体细胞 |
| JP5294673B2 (ja) | 2007-04-02 | 2013-09-18 | 花王株式会社 | 改変微生物 |
| CN113122559A (zh) * | 2020-01-16 | 2021-07-16 | 南京理工大学 | 膜蛋白SecF的表达载体及其表达纯化方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69434807T2 (de) * | 1993-02-26 | 2007-03-29 | Novozymes A/S | Methode und system zur erhöhten produktion von kommerziell wichtigen exoproteinen in gram-positiven bakterien |
| US5945278A (en) * | 1996-07-08 | 1999-08-31 | The Finnish National Public Health Institute | Method and system for enhanced production of commercially important exoproteins in gram-positive bacteria |
-
1998
- 1998-07-15 WO PCT/US1998/014786 patent/WO1999004007A1/en not_active Ceased
- 1998-07-15 US US09/462,844 patent/US6258563B1/en not_active Expired - Lifetime
- 1998-07-15 DE DE69829670T patent/DE69829670T2/de not_active Expired - Lifetime
- 1998-07-15 CA CA2296689A patent/CA2296689C/en not_active Expired - Fee Related
- 1998-07-15 AT AT98935747T patent/ATE292683T1/de not_active IP Right Cessation
- 1998-07-15 EP EP98935747A patent/EP1003873B1/en not_active Expired - Lifetime
- 1998-07-15 DK DK98935747T patent/DK1003873T3/da active
- 1998-07-16 JP JP2000503213A patent/JP2001510047A/ja active Pending
- 1998-07-16 AU AU84931/98A patent/AU8493198A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1003873A1 (en) | 2000-05-31 |
| WO1999004007A8 (en) | 1999-04-22 |
| CA2296689A1 (en) | 1999-01-28 |
| DE69829670D1 (de) | 2005-05-12 |
| WO1999004007A9 (en) | 1999-05-20 |
| DE69829670T2 (de) | 2006-01-12 |
| CA2296689C (en) | 2014-04-01 |
| US6258563B1 (en) | 2001-07-10 |
| EP1003873B1 (en) | 2005-04-06 |
| JP2001510047A (ja) | 2001-07-31 |
| ATE292683T1 (de) | 2005-04-15 |
| WO1999004007A1 (en) | 1999-01-28 |
| AU8493198A (en) | 1999-02-10 |
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