DK1006200T3 - Fremgangsmåde til fremstilling af udvalgte interstreng-tværbindinger i nukleinsyrer og anvendelser deraf - Google Patents

Fremgangsmåde til fremstilling af udvalgte interstreng-tværbindinger i nukleinsyrer og anvendelser deraf

Info

Publication number
DK1006200T3
DK1006200T3 DK99204141.8T DK99204141T DK1006200T3 DK 1006200 T3 DK1006200 T3 DK 1006200T3 DK 99204141 T DK99204141 T DK 99204141T DK 1006200 T3 DK1006200 T3 DK 1006200T3
Authority
DK
Denmark
Prior art keywords
nucleic acid
links
applications
interstrand cross
preparation
Prior art date
Application number
DK99204141.8T
Other languages
English (en)
Inventor
Hendrik Jan Houthoff
Robert Jochem Heetebrij
Hendrikus Johannes Tanke
Anton Klaas Raap
Herman Volkers
Gijswijk Robertus Petrus Maria Van
Original Assignee
Kreatech Biotech Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kreatech Biotech Bv filed Critical Kreatech Biotech Bv
Application granted granted Critical
Publication of DK1006200T3 publication Critical patent/DK1006200T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6832Enhancement of hybridisation reaction
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6841In situ hybridisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
DK99204141.8T 1998-12-03 1999-12-03 Fremgangsmåde til fremstilling af udvalgte interstreng-tværbindinger i nukleinsyrer og anvendelser deraf DK1006200T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98204094A EP1006199A1 (en) 1998-12-03 1998-12-03 Applications with and methods for producing selected interstrand crosslinks in nucleic acid

Publications (1)

Publication Number Publication Date
DK1006200T3 true DK1006200T3 (da) 2011-09-05

Family

ID=8234427

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99204141.8T DK1006200T3 (da) 1998-12-03 1999-12-03 Fremgangsmåde til fremstilling af udvalgte interstreng-tværbindinger i nukleinsyrer og anvendelser deraf

Country Status (11)

Country Link
US (4) US6406850B2 (da)
EP (2) EP1006199A1 (da)
JP (1) JP4838937B2 (da)
AT (1) ATE519859T1 (da)
AU (2) AU778429B2 (da)
CA (1) CA2353643C (da)
DK (1) DK1006200T3 (da)
ES (1) ES2366660T3 (da)
NZ (2) NZ512312A (da)
PT (1) PT1006200E (da)
WO (1) WO2000032814A2 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040266706A1 (en) * 2002-11-05 2004-12-30 Muthiah Manoharan Cross-linked oligomeric compounds and their use in gene modulation
EP1006199A1 (en) * 1998-12-03 2000-06-07 Kreatech Biotechnology B.V. Applications with and methods for producing selected interstrand crosslinks in nucleic acid
US6613582B1 (en) * 1999-05-25 2003-09-02 Board Of Regents, The University Of Texas System Methods for rapid and efficient protein cross-linking
US7473767B2 (en) 2001-07-03 2009-01-06 The Institute For Systems Biology Methods for detection and quantification of analytes in complex mixtures
CA2500551A1 (en) * 2002-09-30 2004-04-08 The Children's Mercy Hospital Subtelomeric dna probes and method of producing the same
US20050016555A1 (en) * 2003-07-24 2005-01-27 Lyles Mark B. Nucleic acid based filters
DE602005022759D1 (de) 2004-12-08 2010-09-16 Gen Probe Inc Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus
ES2886923T3 (es) 2005-09-20 2021-12-21 Menarini Silicon Biosystems Spa Métodos y composición para generar sondas de ADN de secuencia única, marcaje de sondas de ADN y el uso de estas sondas
WO2010065159A1 (en) * 2008-12-02 2010-06-10 Oregon Health & Science University Inhibition of dna polymerases to augment chemotherapeutic and antimicrobial agents
WO2010111602A1 (en) * 2009-03-26 2010-09-30 Trustees Of Boston University Method for imaging on thin solid-state interface between two fluids
EP2734320B1 (en) * 2011-07-19 2016-11-16 Ask Chemicals L. P. Method for curing cold-box foundry shape with gaseous catalyst
WO2016077426A1 (en) 2014-11-11 2016-05-19 Abbott Molecular Inc. Hybridization probes and methods

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4599303A (en) * 1983-12-12 1986-07-08 Hri Associates, Inc. Nucleic acid hybridization assay employing probes crosslinkable to target sequences
AU4181089A (en) * 1988-08-01 1990-03-05 George D. Cimino Identification of allele specific nucleic acid sequences by hybridization with crosslinkable oligonucleotide probes
US4997758A (en) * 1989-01-17 1991-03-05 Iowa State University Research Foundation, Inc. Cross-linking proteins with bimetallic tetracarboxylate compounds of transition metals
EP0472648A4 (en) * 1989-05-18 1992-09-16 Microprobe Corporation Crosslinking oligonucleotides
US5831073A (en) * 1990-10-31 1998-11-03 The Research Foundation Of State University Of New York Ion triggered alkylation of biological targets by silyloxy aromatic agents
US5538869A (en) * 1990-12-13 1996-07-23 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
US5591575A (en) * 1993-04-07 1997-01-07 Amersham International Plc Subtraction hybridization employing aziridinylbenoquinone cross-linking agents
US5767259A (en) * 1994-12-27 1998-06-16 Naxcor Oligonucleotides containing base-free linking groups with photoactivatable side chains
WO1995029921A1 (en) * 1994-04-29 1995-11-09 Perseptive Biosystems, Inc. Activated esters of 1-phenylpyrazolin-5-one for labelling amine-functionalized molecules
PT1019420E (pt) 1995-05-09 2003-12-31 Kreatech Biotech Bv Metodos para a producao de ligandos baseados em platina para ligacao entre marcadores e moleculas bio-orgaicas na marcacao de moleculas bio-organicas com o fim de detectar substancias biologicas de interesse e conjuntos ("kits") de ensaios de diagnosticos
WO1998015565A1 (en) 1996-10-07 1998-04-16 Novartis Ag Chiral ferrocenyls
EP0937090B1 (en) * 1996-10-08 2002-08-07 Kreatech Biotechnology B.V. Methods for labeling nucleotides, labeled nucleotides and useful intermediates
FR2755146B1 (fr) * 1996-10-28 1998-12-04 Centre Nat Rech Scient Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications
EP0973785B1 (en) * 1997-04-10 2003-12-03 Kreatech Biotechnology B.V. Trans-platinum compound, and diagnostic kit
EP1006199A1 (en) * 1998-12-03 2000-06-07 Kreatech Biotechnology B.V. Applications with and methods for producing selected interstrand crosslinks in nucleic acid

Also Published As

Publication number Publication date
CA2353643A1 (en) 2000-06-08
EP1006200B1 (en) 2011-08-10
US6406850B2 (en) 2002-06-18
AU778429B2 (en) 2004-12-02
NZ512312A (en) 2004-04-30
EP1006199A1 (en) 2000-06-07
NZ529273A (en) 2006-04-28
US20020012915A1 (en) 2002-01-31
EP1006200A2 (en) 2000-06-07
CA2353643C (en) 2013-10-15
ES2366660T3 (es) 2011-10-24
AU2005200819A1 (en) 2005-03-17
US20060204987A1 (en) 2006-09-14
AU1696600A (en) 2000-06-19
ATE519859T1 (de) 2011-08-15
US20090023910A1 (en) 2009-01-22
EP1006200A3 (en) 2000-10-11
US20040161743A1 (en) 2004-08-19
PT1006200E (pt) 2011-10-06
WO2000032814A2 (en) 2000-06-08
WO2000032814A3 (en) 2000-11-16
JP4838937B2 (ja) 2011-12-14
JP2002531101A (ja) 2002-09-24

Similar Documents

Publication Publication Date Title
DE69916435D1 (de) Verfahren zur verbesserung der ductilität von nitinol
DE69840748D1 (de) Verfahren zur zubereitung von antisense oligonukleotiden
ATE213005T1 (de) Kontinuierliches polymerisationverfahren von polyamiden
DE3687409D1 (de) Verfahren zur herstellung von schmalen, leitenden linien, von mustern und von verbindern.
DK1006200T3 (da) Fremgangsmåde til fremstilling af udvalgte interstreng-tværbindinger i nukleinsyrer og anvendelser deraf
DE60029589D1 (de) Verfahren zur herstellung von azithromycin
DE69202430D1 (de) Vorrichtung und Verfahren zur Herstellung von elektrischen Simultanverbindungen.
DE69837619D1 (de) Elektrodenstab für funkenbeschichtung, verfahren zu dessen herstellung und verfahren zur beschichtung mit supraschleif-enthaltender schicht
DE69518909D1 (de) Polymere, leitende alumo-silikat-zusammensetzung, element diese zusammensetzung enthaltend und verfahren zu seiner herstellung
DE69818557D1 (de) Fäulnisverhindernde Zusammensetzung, Verfahren zu ihrer Herstellung und damit behandeltes Produkt
DE69006252D1 (de) Elektrischer Steckerstift und Verfahren zu seiner Herstellung.
DE3779930D1 (de) Zusammensetzungen zur oberflaechenbehandlung, polymere dafuer und verfahren zur oberflaechenbehandlung.
DE69833747D1 (de) Polymere, verfahren zu deren herstellung und daraus hergestellte härtbare zusammensetzungen
DE59912242D1 (de) Verfahren zur herstellung von (s,s)-benzyl-2,8-diazabicyclo(4.3.0)nonan
ATE290003T1 (de) Verfahren zur herstellung von pyrazolo-(4,3- d)pyrimidin-7-ones und zwischenprodukte davon
ATE326426T1 (de) Verfahren zur herstellung von wasserstoffperoxid und reaktionsträger zu seiner durchführung
DE3686969D1 (de) Haertbare zusammensetzung, verfahren zu ihrer herstellung und daraus gefertigte gegenstaende.
DE69725176D1 (de) Metallkomplexformende faser, prozess zu deren herstellung, und verfahren zur komplexierung von metallionen mit dieser faser
DE59901657D1 (de) Kontaktiervorrichtung, insbesondere zum ankontaktieren von elektrischen bauelementen und schaltungsträgern, sowie verfahren zu deren herstellung
DE59905926D1 (de) Diisopropylfluorophosphatase sowie deren verwendung und herstellung
DE59905197D1 (de) Verfahren zur herstellung von hexandiol-1,6
DE68908550D1 (de) Verfahren zur herstellung von korrosions-, waerme- und verschleissbestaendigen werkstuecken und so hergestellte werkstuecke.
DE69514122D1 (de) Lösungsmittelfreies verfahren zur herstellung von 2,6 difluorbenzonitril
DE69941670D1 (de) Komputergesteuerte verfahren und system zum implementieren von verteilten anwendungen
ATE227261T1 (de) Verfahren zur herstellung von 2-cyanoindan-1-onen