ATE519859T1 - Verfahren zur herstellung von ausgewählten intermolekularen quervernetzungen in nukleinsäuren und ihre verwendungen - Google Patents
Verfahren zur herstellung von ausgewählten intermolekularen quervernetzungen in nukleinsäuren und ihre verwendungenInfo
- Publication number
- ATE519859T1 ATE519859T1 AT99204141T AT99204141T ATE519859T1 AT E519859 T1 ATE519859 T1 AT E519859T1 AT 99204141 T AT99204141 T AT 99204141T AT 99204141 T AT99204141 T AT 99204141T AT E519859 T1 ATE519859 T1 AT E519859T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- links
- nucleic acids
- complementary
- cross
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 8
- 150000007523 nucleic acids Chemical class 0.000 title abstract 8
- 102000039446 nucleic acids Human genes 0.000 title abstract 8
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000000295 complement effect Effects 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 230000009286 beneficial effect Effects 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 239000003431 cross linking reagent Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6832—Enhancement of hybridisation reaction
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98204094A EP1006199A1 (de) | 1998-12-03 | 1998-12-03 | Verfahren zur Herstellung von Verknüpfungen an ausgewählten Positionen von Nukleinsäuresträngen und deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE519859T1 true ATE519859T1 (de) | 2011-08-15 |
Family
ID=8234427
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99204141T ATE519859T1 (de) | 1998-12-03 | 1999-12-03 | Verfahren zur herstellung von ausgewählten intermolekularen quervernetzungen in nukleinsäuren und ihre verwendungen |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6406850B2 (de) |
| EP (2) | EP1006199A1 (de) |
| JP (1) | JP4838937B2 (de) |
| AT (1) | ATE519859T1 (de) |
| AU (2) | AU778429B2 (de) |
| CA (1) | CA2353643C (de) |
| DK (1) | DK1006200T3 (de) |
| ES (1) | ES2366660T3 (de) |
| NZ (2) | NZ512312A (de) |
| PT (1) | PT1006200E (de) |
| WO (1) | WO2000032814A2 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040266706A1 (en) * | 2002-11-05 | 2004-12-30 | Muthiah Manoharan | Cross-linked oligomeric compounds and their use in gene modulation |
| EP1006199A1 (de) * | 1998-12-03 | 2000-06-07 | Kreatech Biotechnology B.V. | Verfahren zur Herstellung von Verknüpfungen an ausgewählten Positionen von Nukleinsäuresträngen und deren Verwendung |
| US6613582B1 (en) * | 1999-05-25 | 2003-09-02 | Board Of Regents, The University Of Texas System | Methods for rapid and efficient protein cross-linking |
| US7473767B2 (en) | 2001-07-03 | 2009-01-06 | The Institute For Systems Biology | Methods for detection and quantification of analytes in complex mixtures |
| KR20050073466A (ko) * | 2002-09-30 | 2005-07-13 | 칠드런스 머시 호스피탈 | 서브텔로미어 디엔에이 프로브 및 이의 제조 방법 |
| US20050016555A1 (en) * | 2003-07-24 | 2005-01-27 | Lyles Mark B. | Nucleic acid based filters |
| EP1819835B1 (de) | 2004-12-08 | 2010-08-04 | Gen-Probe Incorporated | Nukleinsäuredetektion aus verschiedenen typen des humanen papillomavirus |
| CA2623405C (en) * | 2005-09-20 | 2014-11-25 | Immunivest Corporation | Methods and composition to generate unique sequence dna probes labeling of dna probes and the use of these probes |
| US8715927B2 (en) * | 2008-12-02 | 2014-05-06 | Oregon Health & Science University | Inhibition of DNA polymerases to augment chemotherapeutic and antimicrobial agents |
| CA2756233A1 (en) * | 2009-03-26 | 2010-09-30 | Trustees Of Boston University | Method for imaging on thin solid-state interface between two fluids |
| EP2734320B1 (de) * | 2011-07-19 | 2016-11-16 | Ask Chemicals L. P. | Verfahren zur härtung einer kaltgussform mit einem gasförmigen katalysator |
| JP2017533733A (ja) | 2014-11-11 | 2017-11-16 | アボツト・モレキユラー・インコーポレイテツド | ハイブリダイゼーションプローブおよび方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711955A (en) * | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US4599303A (en) * | 1983-12-12 | 1986-07-08 | Hri Associates, Inc. | Nucleic acid hybridization assay employing probes crosslinkable to target sequences |
| AU4181089A (en) * | 1988-08-01 | 1990-03-05 | George D. Cimino | Identification of allele specific nucleic acid sequences by hybridization with crosslinkable oligonucleotide probes |
| US4997758A (en) * | 1989-01-17 | 1991-03-05 | Iowa State University Research Foundation, Inc. | Cross-linking proteins with bimetallic tetracarboxylate compounds of transition metals |
| EP0472648A4 (en) * | 1989-05-18 | 1992-09-16 | Microprobe Corporation | Crosslinking oligonucleotides |
| US5831073A (en) * | 1990-10-31 | 1998-11-03 | The Research Foundation Of State University Of New York | Ion triggered alkylation of biological targets by silyloxy aromatic agents |
| US5538869A (en) * | 1990-12-13 | 1996-07-23 | Board Of Regents, The University Of Texas System | In-situ hybridization probes for identification and banding of specific human chromosomes and regions |
| US5591575A (en) * | 1993-04-07 | 1997-01-07 | Amersham International Plc | Subtraction hybridization employing aziridinylbenoquinone cross-linking agents |
| US5767259A (en) * | 1994-12-27 | 1998-06-16 | Naxcor | Oligonucleotides containing base-free linking groups with photoactivatable side chains |
| WO1995029921A1 (en) * | 1994-04-29 | 1995-11-09 | Perseptive Biosystems, Inc. | Activated esters of 1-phenylpyrazolin-5-one for labelling amine-functionalized molecules |
| EP1019420B1 (de) | 1995-05-09 | 2003-08-06 | Kreatech Biotechnology B.V. | Verfahren zur herstellung von linkern zwischen markierungsgruppen und bio-organischen molekülen auf der basis von platin für die markierung von bio-organischen molekülen zur entdeckung interessanter biologischer substanzen |
| US6133464A (en) | 1996-10-07 | 2000-10-17 | Novartis Ag | Chiral ferrocenyls |
| NZ334803A (en) * | 1996-10-08 | 2000-05-26 | Kreatech Biotechnology Bv | Method for labeling nucleotides by reacting a reactive platinum compound having two reactive moieties, a labeled moiety and another moiety of a spacer with a nucleotide |
| FR2755146B1 (fr) * | 1996-10-28 | 1998-12-04 | Centre Nat Rech Scient | Procede de pontage selectif et irreversible d'oligonucleotides platines sur de l'arn et ses applications |
| WO1998045304A1 (en) * | 1997-04-10 | 1998-10-15 | Kreatech Biotechnology B.V. | Trans-platinum compound, and diagnostic kit |
| EP1006199A1 (de) * | 1998-12-03 | 2000-06-07 | Kreatech Biotechnology B.V. | Verfahren zur Herstellung von Verknüpfungen an ausgewählten Positionen von Nukleinsäuresträngen und deren Verwendung |
-
1998
- 1998-12-03 EP EP98204094A patent/EP1006199A1/de not_active Withdrawn
-
1999
- 1999-12-03 PT PT99204141T patent/PT1006200E/pt unknown
- 1999-12-03 CA CA2353643A patent/CA2353643C/en not_active Expired - Fee Related
- 1999-12-03 DK DK99204141.8T patent/DK1006200T3/da active
- 1999-12-03 NZ NZ512312A patent/NZ512312A/en not_active IP Right Cessation
- 1999-12-03 WO PCT/NL1999/000740 patent/WO2000032814A2/en not_active Ceased
- 1999-12-03 US US09/454,404 patent/US6406850B2/en not_active Expired - Lifetime
- 1999-12-03 NZ NZ529273A patent/NZ529273A/en unknown
- 1999-12-03 AU AU16966/00A patent/AU778429B2/en not_active Ceased
- 1999-12-03 AT AT99204141T patent/ATE519859T1/de active
- 1999-12-03 EP EP99204141A patent/EP1006200B1/de not_active Expired - Lifetime
- 1999-12-03 ES ES99204141T patent/ES2366660T3/es not_active Expired - Lifetime
- 1999-12-03 JP JP2000585445A patent/JP4838937B2/ja not_active Expired - Lifetime
-
2001
- 2001-12-05 US US10/005,371 patent/US20040161743A1/en not_active Abandoned
-
2005
- 2005-02-23 AU AU2005200819A patent/AU2005200819A1/en not_active Abandoned
-
2006
- 2006-02-15 US US11/354,679 patent/US20060204987A1/en not_active Abandoned
-
2008
- 2008-08-25 US US12/197,590 patent/US20090023910A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000032814A3 (en) | 2000-11-16 |
| AU1696600A (en) | 2000-06-19 |
| ES2366660T3 (es) | 2011-10-24 |
| EP1006200A3 (de) | 2000-10-11 |
| JP2002531101A (ja) | 2002-09-24 |
| WO2000032814A2 (en) | 2000-06-08 |
| US20060204987A1 (en) | 2006-09-14 |
| EP1006200A2 (de) | 2000-06-07 |
| US20090023910A1 (en) | 2009-01-22 |
| NZ529273A (en) | 2006-04-28 |
| DK1006200T3 (da) | 2011-09-05 |
| AU2005200819A1 (en) | 2005-03-17 |
| US6406850B2 (en) | 2002-06-18 |
| CA2353643A1 (en) | 2000-06-08 |
| EP1006200B1 (de) | 2011-08-10 |
| US20040161743A1 (en) | 2004-08-19 |
| AU778429B2 (en) | 2004-12-02 |
| US20020012915A1 (en) | 2002-01-31 |
| EP1006199A1 (de) | 2000-06-07 |
| JP4838937B2 (ja) | 2011-12-14 |
| NZ512312A (en) | 2004-04-30 |
| PT1006200E (pt) | 2011-10-06 |
| CA2353643C (en) | 2013-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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