DK1007023T3 - 1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutylaminderivater til sænkning af urinniveauet hos mennesker - Google Patents

1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutylaminderivater til sænkning af urinniveauet hos mennesker

Info

Publication number: DK1007023T3
Authority: DK; Denmark
Prior art keywords: humans; pct; cyclobutyl; chlorophenyl; methylbutylamine
Prior art date: 1996-09-25

Application number

DK97942030T

Other languages

English (en)

Inventor

Finian Kelly Peter

Paul Jones Stephen

Original Assignee

Abbott Gmbh & Co Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-25

Filing date

1997-09-15

Publication date

2003-08-25

1997-09-15 Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg

2003-08-25 Application granted granted Critical

2003-08-25 Publication of DK1007023T3 publication Critical patent/DK1007023T3/da

Links

WQSACWZKKZPCHN-UHFFFAOYSA-N 1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutan-1-amine Chemical class C=1C=C(Cl)C=CC=1C1(C(N)CC(C)C)CCC1 WQSACWZKKZPCHN-UHFFFAOYSA-N 0.000 title 1
210000002700 urine Anatomy 0.000 title 1
201000005569 Gout Diseases 0.000 abstract 1
201000001431 Hyperuricemia Diseases 0.000 abstract 1
LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 abstract 1
TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 abstract 1
UWAOJIWUVCMBAZ-UHFFFAOYSA-N [1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl]-dimethylazanium;chloride Chemical compound Cl.C=1C=C(Cl)C=CC=1C1(C(N(C)C)CC(C)C)CCC1 UWAOJIWUVCMBAZ-UHFFFAOYSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000029078 coronary artery disease Diseases 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
150000004682 monohydrates Chemical class 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229940116269 uric acid Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Obesity (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Materials For Medical Uses (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Crystals, And After-Treatments Of Crystals (AREA)

DK97942030T 1996-09-25 1997-09-15 1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutylaminderivater til sænkning af urinniveauet hos mennesker DK1007023T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9619962.5A GB9619962D0 (en)	1996-09-25	1996-09-25	Medical treatment
PCT/EP1997/005034 WO1998013033A1 (en)	1996-09-25	1997-09-15	Medical treatment

Publications (1)

Publication Number	Publication Date
DK1007023T3 true DK1007023T3 (da)	2003-08-25

Family

ID=10800448

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97942030T DK1007023T3 (da)	1996-09-25	1997-09-15	1-[1-(4-chlorphenyl)cyclobutyl]-3-methylbutylaminderivater til sænkning af urinniveauet hos mennesker

Country Status (26)

Country	Link
US (1)	US6162831A (da)
EP (1)	EP1007023B1 (da)
JP (1)	JP2001501608A (da)
KR (1)	KR20000048568A (da)
CN (1)	CN1231604A (da)
AT (1)	ATE239460T1 (da)
AU (1)	AU722129B2 (da)
BG (1)	BG103278A (da)
BR (1)	BR9711414A (da)
CA (1)	CA2266438A1 (da)
DE (1)	DE69721838T2 (da)
DK (1)	DK1007023T3 (da)
ES (1)	ES2199374T3 (da)
GB (1)	GB9619962D0 (da)
HR (1)	HRP970519A2 (da)
HU (1)	HUP9904545A3 (da)
IL (1)	IL128851A (da)
NO (1)	NO991425D0 (da)
NZ (1)	NZ334668A (da)
PL (1)	PL332423A1 (da)
PT (1)	PT1007023E (da)
SK (1)	SK32199A3 (da)
TR (1)	TR199900649T2 (da)
TW (1)	TW415842B (da)
WO (1)	WO1998013033A1 (da)
ZA (1)	ZA978573B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6476078B2 (en)	1999-08-11	2002-11-05	Sepracor, Inc.	Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
US6339106B1 (en)	1999-08-11	2002-01-15	Sepracor, Inc.	Methods and compositions for the treatment and prevention of sexual dysfunction
US6331571B1 (en)	1998-08-24	2001-12-18	Sepracor, Inc.	Methods of treating and preventing attention deficit disorders
US6974838B2 (en)	1998-08-24	2005-12-13	Sepracor Inc.	Methods of treating or preventing pain using sibutramine metabolites
US6552087B1 (en)	1999-03-19	2003-04-22	Abbott Gmbh & Co. Kg	Therapeutic agent comprising (+)-sibutramine
CA2366660A1 (en) *	1999-03-19	2000-09-28	Carl M. Mendel	Treatment of osteoarthritis
US6399826B1 (en)	1999-08-11	2002-06-04	Sepracor Inc.	Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
WO2002083631A1 (en)	2001-04-13	2002-10-24	Sepracor Inc.	Methods of preparing didesmethylsibutramine and other sibutramine derivatives
US11103542B2 (en)	2002-03-13	2021-08-31	Kibow Biotech, Inc.	Composition and method for maintaining healthy kidney function
US9655932B2 (en) *	2002-03-13	2017-05-23	Kibow Biotech, Inc.	Composition and method for preventing or treating gout or hyperuricemia
MXPA05003355A (es) *	2002-10-05	2005-10-18	Hanmi Pharm Ind Co Ltd	Composicion farmaceutica que comprende semihidrato de metansulfonato de sibutramina cristalino.
US20050131074A1 (en) *	2003-08-04	2005-06-16	Beckman Kristen M.	Methods for treating metabolic syndrome
US8557831B2 (en) *	2004-07-21	2013-10-15	University Of Florida Research Foundation, Inc.	Compositions and methods for treatment and prevention of insulin resistance
KR100627687B1 (ko) *	2005-04-20	2006-09-25	주식회사 씨티씨바이오	시부트라민 유리염기 함유 조성물 및 이의 제조방법
BRPI0716002A2 (pt) *	2006-11-22	2013-07-30	Sk Chemicals Co Ltd	complexo de inclusço, processo de preparaÇço de um complexo de inclusço e composiÇço de tratamento e prevenÇço de hipocondria e obesidade
WO2018125735A1 (en)	2016-12-29	2018-07-05	Kibow Biotech, Inc.	Composition and method for maintaining healthy kidney function
AU2019370565A1 (en) *	2018-11-02	2021-06-24	Ampersand Biopharmaceuticals, Inc.	Management of risk of cation overload and electrolyte imbalance with topically applied buffers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE52768B1 (en) *	1981-04-06	1988-02-17	Boots Co Ltd	1-arylcyclobutylalkylamine compounds useful as therapeutic agents
GB8531071D0 (en) *	1985-12-17	1986-01-29	Boots Co Plc	Therapeutic compound
GB8704777D0 (en) *	1987-02-28	1987-04-01	Boots Co Plc	Medical treatment
JP2675573B2 (ja) *	1988-03-31	1997-11-12	科研製薬株式会社	脳機能改善剤
IE61928B1 (en) *	1988-11-29	1994-11-30	Boots Co Plc	Treatment of obesity
CA2139000A1 (en) *	1992-06-23	1994-01-06	James W. Young	Methods and compositions for treating depression and other disorders using optically pure(+) sibutramine
AU4542893A (en) *	1992-06-23	1994-01-24	Sepracor, Inc.	Methods and compositions for treating depression and other disorders using optically pure (-) sibutramine
US5459164A (en) *	1994-02-03	1995-10-17	Boots Pharmaceuticals, Inc.	Medical treatment

1996
- 1996-09-25 GB GBGB9619962.5A patent/GB9619962D0/en active Pending
1997
- 1997-09-15 NZ NZ334668A patent/NZ334668A/xx unknown
- 1997-09-15 CA CA002266438A patent/CA2266438A1/en not_active Abandoned
- 1997-09-15 BR BR9711414-6A patent/BR9711414A/pt not_active Application Discontinuation
- 1997-09-15 AU AU43851/97A patent/AU722129B2/en not_active Ceased
- 1997-09-15 WO PCT/EP1997/005034 patent/WO1998013033A1/en not_active Ceased
- 1997-09-15 HU HU9904545A patent/HUP9904545A3/hu unknown
- 1997-09-15 CN CN97198232A patent/CN1231604A/zh active Pending
- 1997-09-15 PL PL97332423A patent/PL332423A1/xx unknown
- 1997-09-15 DE DE69721838T patent/DE69721838T2/de not_active Expired - Fee Related
- 1997-09-15 DK DK97942030T patent/DK1007023T3/da active
- 1997-09-15 SK SK321-99A patent/SK32199A3/sk unknown
- 1997-09-15 TR TR1999/00649T patent/TR199900649T2/xx unknown
- 1997-09-15 EP EP97942030A patent/EP1007023B1/en not_active Expired - Lifetime
- 1997-09-15 KR KR1019990702491A patent/KR20000048568A/ko not_active Ceased
- 1997-09-15 IL IL12885197A patent/IL128851A/xx not_active IP Right Cessation
- 1997-09-15 AT AT97942030T patent/ATE239460T1/de not_active IP Right Cessation
- 1997-09-15 ES ES97942030T patent/ES2199374T3/es not_active Expired - Lifetime
- 1997-09-15 JP JP10515217A patent/JP2001501608A/ja active Pending
- 1997-09-15 PT PT97942030T patent/PT1007023E/pt unknown
- 1997-09-15 US US09/269,339 patent/US6162831A/en not_active Expired - Fee Related
- 1997-09-25 TW TW086113992A patent/TW415842B/zh not_active IP Right Cessation
- 1997-09-25 HR HR9619962.5A patent/HRP970519A2/hr not_active Application Discontinuation
- 1997-09-25 ZA ZA978573A patent/ZA978573B/xx unknown
1999
- 1999-03-24 NO NO991425A patent/NO991425D0/no unknown
- 1999-03-24 BG BG103278A patent/BG103278A/xx unknown

Also Published As

Publication number	Publication date
NZ334668A (en)	2000-07-28
KR20000048568A (ko)	2000-07-25
TW415842B (en)	2000-12-21
CN1231604A (zh)	1999-10-13
EP1007023A1 (en)	2000-06-14
IL128851A (en)	2001-08-26
PT1007023E (pt)	2003-08-29
PL332423A1 (en)	1999-09-13
DE69721838D1 (de)	2003-06-12
NO991425L (no)	1999-03-24
EP1007023B1 (en)	2003-05-07
AU4385197A (en)	1998-04-17
JP2001501608A (ja)	2001-02-06
CA2266438A1 (en)	1998-04-02
ATE239460T1 (de)	2003-05-15
HUP9904545A3 (en)	2000-12-28
TR199900649T2 (xx)	1999-07-21
DE69721838T2 (de)	2004-01-22
NO991425D0 (no)	1999-03-24
US6162831A (en)	2000-12-19
GB9619962D0 (en)	1996-11-13
SK32199A3 (en)	1999-12-10
BR9711414A (pt)	2000-04-25
HRP970519A2 (en)	1998-08-31
HUP9904545A2 (hu)	2000-11-28
BG103278A (en)	2000-01-31
WO1998013033A1 (en)	1998-04-02
AU722129B2 (en)	2000-07-20
ES2199374T3 (es)	2004-02-16
ZA978573B (en)	1999-03-25
IL128851A0 (en)	2000-01-31

Publication	Publication Date	Title
NO991425D0 (no)	1999-03-24	Medisinsk behandling
NO20014479L (no)	2001-11-02	Fremgangsmåte ved behandling av spiseforstyrrelser
NO20021328L (no)	2002-05-21	Pyrazolopyrimidier som terapeutiske midler
NO971471L (no)	1997-05-30	Nye karboksamider med fungicid aktivitet
IL112515A0 (en)	1995-12-08	N,n-dimethyl-1-Ú1-(4-chlorophenyl) cyclobutyl¾-3-methylbutylamine in the treatment of non-insulin dependent diabetes mellitus
WO2000056315A8 (en)	2001-06-21	Treatment of pain
DK1169029T3 (da)	2005-08-29	Anvendelse af sibutramin eller et derivat deraf til behandling af sövnforstyrrelser
MXPA01009468A (es)	2004-03-19	Tratamiento de hipertension pulmonar.
DK413188D0 (da)	1988-07-22	Benzimidazol-derivater til terapeutisk anvendelse og fremgangsmaade til fremstilling deraf
MXPA01009461A (es)	2004-03-19	Tratamiento de osteoartritis.
KR950016739A (ko)	1995-07-20	강박관념 질환 및 소모성 질환을 억제하는 방법
HK1044703A1 (zh)	2002-11-01	裂孔疝的治疗方法
MXPA01009465A (es)	2004-03-19	Perdida de peso despues del embarazo.
BG105996A (en)	2002-06-28	Method of treating eating disorders
RU97113704A (ru)	1999-07-20	Способы ингибирования воздействий гормонов роста