DK1011648T4 - Kombination af tyrosinkinase-inhibitor og kemisk kastration til behandling af prostatacancer - Google Patents
Kombination af tyrosinkinase-inhibitor og kemisk kastration til behandling af prostatacancerInfo
- Publication number
- DK1011648T4 DK1011648T4 DK98942057T DK98942057T DK1011648T4 DK 1011648 T4 DK1011648 T4 DK 1011648T4 DK 98942057 T DK98942057 T DK 98942057T DK 98942057 T DK98942057 T DK 98942057T DK 1011648 T4 DK1011648 T4 DK 1011648T4
- Authority
- DK
- Denmark
- Prior art keywords
- tyrosine kinase
- kinase inhibitor
- prostate cancer
- combination
- chemical castration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5589197P | 1997-08-15 | 1997-08-15 | |
| PCT/US1998/016849 WO1999008668A2 (fr) | 1997-08-15 | 1998-08-13 | Inhibiteur de tyrosine kinase combine a une castration chimique pour traiter un cancer de la prostate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK1011648T3 DK1011648T3 (da) | 2001-12-27 |
| DK1011648T4 true DK1011648T4 (da) | 2005-10-24 |
Family
ID=22000842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98942057T DK1011648T4 (da) | 1997-08-15 | 1998-08-13 | Kombination af tyrosinkinase-inhibitor og kemisk kastration til behandling af prostatacancer |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5985877A (fr) |
| EP (1) | EP1011648B2 (fr) |
| JP (1) | JP2001515032A (fr) |
| KR (1) | KR100612161B1 (fr) |
| CN (1) | CN1147317C (fr) |
| AT (1) | ATE208210T1 (fr) |
| AU (1) | AU737092B2 (fr) |
| BR (1) | BR9812122A (fr) |
| CA (1) | CA2299471C (fr) |
| CZ (1) | CZ297198B6 (fr) |
| DE (1) | DE69802422T3 (fr) |
| DK (1) | DK1011648T4 (fr) |
| EA (1) | EA002525B1 (fr) |
| ES (1) | ES2163293T5 (fr) |
| HU (1) | HUP0003194A3 (fr) |
| NO (1) | NO325526B1 (fr) |
| NZ (2) | NZ517497A (fr) |
| PL (1) | PL193375B1 (fr) |
| PT (1) | PT1011648E (fr) |
| TR (1) | TR200000415T2 (fr) |
| UA (1) | UA61970C2 (fr) |
| WO (1) | WO1999008668A2 (fr) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUP0103761A3 (en) * | 1998-10-08 | 2002-11-28 | Takeda Chemical Industries Ltd | Compositions for retarding change of hormone-dependent cancer into hormone-independent cancer and their use |
| GB0007371D0 (en) * | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0008368D0 (en) * | 2000-04-06 | 2000-05-24 | Astrazeneca Ab | Combination product |
| US20020169154A1 (en) * | 2001-04-04 | 2002-11-14 | Cephalon, Inc. | Novel methods and compositions involving trk tyrosine kinase inhibitors and antineoplastic agents |
| AU2002315306B2 (en) * | 2001-05-08 | 2007-05-17 | Merck Patent Gmbh | Combination therapy using anti-EGFR antibodies and anti-hormonal agents |
| SE0101697D0 (sv) * | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Pharmaceutical combination |
| IL144583A0 (en) * | 2001-07-26 | 2002-05-23 | Peptor Ltd | Chimeric protein kinase inhibitors |
| WO2003015820A1 (fr) * | 2001-08-10 | 2003-02-27 | Takeda Chemical Industries, Ltd. | Medicaments combines d'agoniste de la gnrh |
| ES2388170T3 (es) * | 2001-08-24 | 2012-10-09 | Uvic Industry Partnerships Inc. | Proaerolisina que contiene secuencias de activación de proteasa y métodos de uso para el tratamiento del cáncer de próstata |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| KR20110094361A (ko) | 2003-04-11 | 2011-08-23 | 메디뮨 엘엘씨 | 재조합 il9 항체 및 그의 용도 |
| US20040224000A1 (en) * | 2003-05-05 | 2004-11-11 | Romano Deghenghi | Implants for non-radioactive brachytherapy of hormonal-insensitive cancers |
| IL156429A0 (en) * | 2003-06-12 | 2004-01-04 | Peptor Ltd | Cell permeable conjugates of peptides for inhibition of protein kinases |
| US20050048617A1 (en) | 2003-08-18 | 2005-03-03 | Medimmune, Inc. | Humanization of antibodies |
| WO2006047639A2 (fr) | 2004-10-27 | 2006-05-04 | Medimmune, Inc. | Modulation d'une specificite d'anticorps par adaptation sur mesure de son affinite a un antigene apparente |
| EP1869192B1 (fr) | 2005-03-18 | 2016-01-20 | MedImmune, LLC | Rearrangement de l'infrastructure d'anticorps |
| US8916161B2 (en) | 2005-06-14 | 2014-12-23 | Sophiris Bio Inc. | Method of treating or preventing benign prostatic hyperplasia using modified pore-forming proteins |
| KR20080025174A (ko) | 2005-06-23 | 2008-03-19 | 메디뮨 인코포레이티드 | 응집 및 단편화 프로파일이 최적화된 항체 제제 |
| KR101353706B1 (ko) * | 2006-02-03 | 2014-02-18 | 유니버시티 오브 워싱톤 | 전립선 암 치료용 보강제로서의 ⅰgf-ⅰr 길항제 |
| US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
| EA021255B1 (ru) | 2006-08-28 | 2015-05-29 | Киова Хакко Кирин Ко., Лимитед | Антагонистические моноклональные антитела человека, специфичные в отношении light человека |
| US20100209434A1 (en) | 2007-03-30 | 2010-08-19 | Medimmune, Llc | Antibody formulation |
| US20090130195A1 (en) | 2007-10-17 | 2009-05-21 | Mildred Acevedo-Duncan | Prostate carcinogenesis predictor |
| US12161734B2 (en) | 2009-07-02 | 2024-12-10 | Sloan-Kettering Institute For Cancer Research | Multimodal silica-based nanoparticles |
| EP3763740A1 (fr) | 2011-01-26 | 2021-01-13 | Celldex Therapeutics, Inc. | Anticorps anti-kit et leurs utilisations |
| CN104812775B (zh) | 2012-07-25 | 2019-05-03 | 塞尔德克斯医疗公司 | 抗kit抗体及其用途 |
| JP2015533832A (ja) | 2012-10-09 | 2015-11-26 | アイジェニカ バイオセラピューティクス インコーポレイテッド | 抗C16orf54抗体およびその使用方法 |
| SG10201708143QA (en) | 2013-06-06 | 2017-11-29 | Pf Medicament | Anti-c10orf54 antibodies and uses thereof |
| WO2015053871A2 (fr) | 2013-08-26 | 2015-04-16 | MabVax Therapeutics, Inc. | Acides nucléiques codant des anticorps humains contre sialyl-lewisa |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| KR102226248B1 (ko) | 2014-06-04 | 2021-03-12 | 바이오엔테크 리서치 앤드 디벨롭먼트 인코포레이티드 | 강글리오사이드 gd2에 대한 사람 단클론 항체 |
| WO2016094837A2 (fr) | 2014-12-11 | 2016-06-16 | Igenica Biotherapeutics, Inc. | Anticorps anti-c10orf54 et leurs utilisations |
| KR102740384B1 (ko) | 2015-03-03 | 2024-12-06 | 키맵 리미티드 | 항체, 용도 및 방법 |
| JP6974178B2 (ja) | 2015-05-29 | 2021-12-01 | メモリアル スローン ケタリング キャンサー センター | フェロトーシスを介して栄養欠乏がん細胞の細胞死を誘導するための極小ナノ粒子を使用する処置方法 |
| EP3383908A1 (fr) | 2015-12-02 | 2018-10-10 | Stsciences, Inc. | Anticorps spécifiques au btla glycosylé (atténuateur de lymphocytes b et t) |
| MX2018006613A (es) | 2015-12-02 | 2019-01-30 | Stcube & Co Inc | Anticuerpos y moleculas que se unen inmunoespecificamente a btn1a1 y los usos terapeuticos de los mismos. |
| US11779604B2 (en) | 2016-11-03 | 2023-10-10 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses and methods |
| EP3634500B1 (fr) | 2017-05-25 | 2023-10-25 | Memorial Sloan-Kettering Cancer Center | Nanoparticules ultra-petites marquées avec du zirconium-89 et leurs procédés |
| WO2018222685A1 (fr) | 2017-05-31 | 2018-12-06 | Stcube & Co., Inc. | Méthodes de traitement du cancer à l'aide d'anticorps et de molécules se liant de manière immunospécifique à btn1a1 |
| KR20250036941A (ko) | 2017-05-31 | 2025-03-14 | 주식회사 에스티큐브앤컴퍼니 | Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도 |
| EP3635007A1 (fr) | 2017-06-06 | 2020-04-15 | STCube & Co., Inc. | Procédés de traitement du cancer à l'aide d'anticorps et de molécules se liant à btn1a1 ou des ligands de btn1a1 |
| RU2667906C1 (ru) * | 2017-09-11 | 2018-09-25 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Производное класса N-гликозидов индоло[2,3-а]пирроло[3,4-с]карбазол-5,7-дионов - N-{ 12-(β-D-ксилопиранозил)-5,7-диоксо-индоло[2,3-а]пирроло[3,4-с] карбазол-6-ил} пиридин-2-карбоксамид, обладающее цитотоксической и противоопухолевой активностью |
| CN111630069B (zh) | 2017-10-13 | 2024-05-31 | 勃林格殷格翰国际有限公司 | 针对Thomsen-nouvelle(Tn)抗原的人抗体 |
| IL280199B2 (en) | 2018-07-20 | 2025-08-01 | Pf Medicament | Receptor for vista |
| WO2021138391A1 (fr) | 2019-12-30 | 2021-07-08 | Tyra Biosciences, Inc. | Composés d'indazole |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659695A (en) * | 1985-02-08 | 1987-04-21 | Fernand Labrie | Method of treatment of prostate cancer |
| US4923986A (en) † | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
| GB9300059D0 (en) * | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
| US5461146A (en) † | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
| EP0699204B1 (fr) * | 1993-05-28 | 1998-04-15 | Cephalon, Inc. | Utilisation de derives de l'indolocarbozole pour traiter une affection de la prostate |
| WO1995024190A2 (fr) * | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Inhibiteurs de tyrosine-kinase receptrice destines a inhiber les troubles lies a la proliferation cellulaire et compositions les contenant |
| SE506019C2 (sv) * | 1994-05-17 | 1997-11-03 | Forskarpatent I Linkoeping Ab | Ljuskälla av konjugerade polymerer med spänningsstyrd färg samt metod för tillverkning av ljuskällan |
| US5591855A (en) * | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5594009A (en) † | 1994-10-14 | 1997-01-14 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
| US5650407A (en) * | 1995-04-05 | 1997-07-22 | Cephalon, Inc. | Selected soluble esters of hydroxyl-containing indolocarbazoles |
| GB9508538D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5659407A (en) * | 1995-06-06 | 1997-08-19 | Apple Computer, Inc. | Method and system for rendering achromatic image data for image output devices |
| CA2260999C (fr) † | 1996-07-19 | 2006-07-11 | Takeda Chemical Industries, Ltd. | Composes heterocycliques, leur production et leur utilisation en tant qu'inhibiteurs de tyrosine kinase |
-
1998
- 1998-08-13 EA EA200000220A patent/EA002525B1/ru not_active IP Right Cessation
- 1998-08-13 EP EP98942057A patent/EP1011648B2/fr not_active Expired - Lifetime
- 1998-08-13 KR KR1020007001481A patent/KR100612161B1/ko not_active Expired - Fee Related
- 1998-08-13 TR TR2000/00415T patent/TR200000415T2/xx unknown
- 1998-08-13 ES ES98942057T patent/ES2163293T5/es not_active Expired - Lifetime
- 1998-08-13 HU HU0003194A patent/HUP0003194A3/hu unknown
- 1998-08-13 WO PCT/US1998/016849 patent/WO1999008668A2/fr not_active Ceased
- 1998-08-13 US US09/133,567 patent/US5985877A/en not_active Expired - Fee Related
- 1998-08-13 AT AT98942057T patent/ATE208210T1/de not_active IP Right Cessation
- 1998-08-13 AU AU90192/98A patent/AU737092B2/en not_active Ceased
- 1998-08-13 DE DE69802422T patent/DE69802422T3/de not_active Expired - Lifetime
- 1998-08-13 PL PL98338885A patent/PL193375B1/pl not_active IP Right Cessation
- 1998-08-13 NZ NZ517497A patent/NZ517497A/en unknown
- 1998-08-13 NZ NZ502646A patent/NZ502646A/en unknown
- 1998-08-13 CN CNB988081741A patent/CN1147317C/zh not_active Expired - Fee Related
- 1998-08-13 DK DK98942057T patent/DK1011648T4/da active
- 1998-08-13 CA CA002299471A patent/CA2299471C/fr not_active Expired - Fee Related
- 1998-08-13 CZ CZ20000469A patent/CZ297198B6/cs not_active IP Right Cessation
- 1998-08-13 JP JP2000509408A patent/JP2001515032A/ja active Pending
- 1998-08-13 BR BR9812122-7A patent/BR9812122A/pt not_active IP Right Cessation
- 1998-08-13 PT PT98942057T patent/PT1011648E/pt unknown
- 1998-08-13 UA UA2000031438A patent/UA61970C2/uk unknown
-
2000
- 2000-02-14 NO NO20000732A patent/NO325526B1/no not_active IP Right Cessation
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