DK1015446T3 - 4-(Piperidinyl)-1H-2-benzopyranderivater, der er nyttige som antipsykotiske midler - Google Patents

4-(Piperidinyl)-1H-2-benzopyranderivater, der er nyttige som antipsykotiske midler

Info

Publication number
DK1015446T3
DK1015446T3 DK98902628T DK98902628T DK1015446T3 DK 1015446 T3 DK1015446 T3 DK 1015446T3 DK 98902628 T DK98902628 T DK 98902628T DK 98902628 T DK98902628 T DK 98902628T DK 1015446 T3 DK1015446 T3 DK 1015446T3
Authority
DK
Denmark
Prior art keywords
piperidinyl
derivatives useful
antipsychotic agents
benzopyran derivatives
benzopyran
Prior art date
Application number
DK98902628T
Other languages
English (en)
Inventor
Joseph T Strupczewski
Kenneth J Bordeau
Shelley L Pavlek
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Application granted granted Critical
Publication of DK1015446T3 publication Critical patent/DK1015446T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK98902628T 1997-02-07 1998-01-20 4-(Piperidinyl)-1H-2-benzopyranderivater, der er nyttige som antipsykotiske midler DK1015446T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79710797A 1997-02-07 1997-02-07
PCT/US1998/000979 WO1998034933A1 (en) 1997-02-07 1998-01-20 (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents

Publications (1)

Publication Number Publication Date
DK1015446T3 true DK1015446T3 (da) 2003-07-14

Family

ID=25169927

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98902628T DK1015446T3 (da) 1997-02-07 1998-01-20 4-(Piperidinyl)-1H-2-benzopyranderivater, der er nyttige som antipsykotiske midler

Country Status (21)

Country Link
EP (1) EP1015446B1 (da)
JP (1) JP4177461B2 (da)
KR (1) KR100509878B1 (da)
CN (1) CN1092653C (da)
AR (1) AR011614A1 (da)
AT (1) ATE236150T1 (da)
AU (1) AU725301B2 (da)
BR (1) BRPI9807312B8 (da)
CA (1) CA2281702C (da)
CY (1) CY2324B1 (da)
DE (1) DE69812980T2 (da)
DK (1) DK1015446T3 (da)
ES (1) ES2194303T3 (da)
HU (1) HUP0001308A3 (da)
IL (1) IL131243A (da)
NO (1) NO318936B1 (da)
NZ (1) NZ336719A (da)
PT (1) PT1015446E (da)
TW (1) TW518333B (da)
WO (1) WO1998034933A1 (da)
ZA (1) ZA98831B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE459618T1 (de) * 2004-04-29 2010-03-15 Aventis Pharma Inc 3-piperidinylisochroman-5-ole als dopaminagonisten
EP1748767B1 (en) 2004-05-28 2011-12-28 Unigen, Inc. 1-(3-methyl-2,4-dimethoxyphenyl)-3-(2',4'-dihydroxyphenyl)-propane as a potent tyrosinase inhibitor
AU2008280187B2 (en) 2007-07-26 2013-05-16 F. Hoffmann-La Roche Ag Dual modulators of 5-HT2A and D3 receptors
KR101988329B1 (ko) 2008-07-21 2019-06-12 유니젠, 인크. 일련의 피부-화이트닝(라이트닝) 화합물
US8877778B2 (en) 2010-12-15 2014-11-04 Hoffmann-La Roche Inc. Benzofurane compounds
CN102079720B (zh) * 2011-01-20 2013-02-06 蚌埠丰原医药科技发展有限公司 一种制备1-苄基-4-哌啶甲醛的方法
JP6216312B2 (ja) 2011-03-24 2017-10-18 ユニゲン・インコーポレーテッド ジアリールプロパンを調製するための化合物及び方法
US8921397B2 (en) 2011-05-04 2014-12-30 Hoffmann-La Roche Inc. Benzofurane-piperidine compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552004A (en) * 1976-05-26 1979-09-05 Takeda Chemical Industries Ltd Isochroman derivatives
US4963568A (en) * 1989-05-31 1990-10-16 Abbott Laboratories Dopamine agonists

Also Published As

Publication number Publication date
NO318936B1 (no) 2005-05-30
AU5923798A (en) 1998-08-26
HUP0001308A2 (hu) 2001-06-28
PT1015446E (pt) 2003-08-29
KR100509878B1 (ko) 2005-08-25
ES2194303T3 (es) 2003-11-16
NZ336719A (en) 2000-10-27
EP1015446B1 (en) 2003-04-02
CA2281702A1 (en) 1998-08-13
ATE236150T1 (de) 2003-04-15
CY2324B1 (en) 2003-11-14
HUP0001308A3 (en) 2001-07-30
KR20000070862A (ko) 2000-11-25
IL131243A (en) 2004-02-19
DE69812980D1 (de) 2003-05-08
ZA98831B (en) 1998-08-07
BR9807312B1 (pt) 2013-10-29
WO1998034933A1 (en) 1998-08-13
EP1015446A1 (en) 2000-07-05
BRPI9807312B8 (pt) 2016-09-13
CN1092653C (zh) 2002-10-16
JP4177461B2 (ja) 2008-11-05
NO993812D0 (no) 1999-08-06
TW518333B (en) 2003-01-21
DE69812980T2 (de) 2003-11-13
CN1246859A (zh) 2000-03-08
IL131243A0 (en) 2001-01-28
AU725301B2 (en) 2000-10-12
NO993812L (no) 1999-10-05
CA2281702C (en) 2006-04-11
AR011614A1 (es) 2000-08-30
HK1027812A1 (en) 2001-01-23
JP2001512436A (ja) 2001-08-21
BR9807312A (pt) 2000-05-02

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