ATE236150T1 - (4-piperidinyl)-1h-2-benzopyran derivate verwendbar als antipsychotische mittel - Google Patents
(4-piperidinyl)-1h-2-benzopyran derivate verwendbar als antipsychotische mittelInfo
- Publication number
- ATE236150T1 ATE236150T1 AT98902628T AT98902628T ATE236150T1 AT E236150 T1 ATE236150 T1 AT E236150T1 AT 98902628 T AT98902628 T AT 98902628T AT 98902628 T AT98902628 T AT 98902628T AT E236150 T1 ATE236150 T1 AT E236150T1
- Authority
- AT
- Austria
- Prior art keywords
- piperidinyl
- antipsychotic agents
- derivatives usable
- benzopyrane derivatives
- benzopyrane
- Prior art date
Links
- BGQDJILSOPGZQP-UHFFFAOYSA-N 4-(1h-isochromen-1-yl)piperidine Chemical class C1CNCCC1C1C2=CC=CC=C2C=CO1 BGQDJILSOPGZQP-UHFFFAOYSA-N 0.000 title 1
- 239000000164 antipsychotic agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79710797A | 1997-02-07 | 1997-02-07 | |
| PCT/US1998/000979 WO1998034933A1 (en) | 1997-02-07 | 1998-01-20 | (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE236150T1 true ATE236150T1 (de) | 2003-04-15 |
Family
ID=25169927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98902628T ATE236150T1 (de) | 1997-02-07 | 1998-01-20 | (4-piperidinyl)-1h-2-benzopyran derivate verwendbar als antipsychotische mittel |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1015446B1 (de) |
| JP (1) | JP4177461B2 (de) |
| KR (1) | KR100509878B1 (de) |
| CN (1) | CN1092653C (de) |
| AR (1) | AR011614A1 (de) |
| AT (1) | ATE236150T1 (de) |
| AU (1) | AU725301B2 (de) |
| BR (1) | BRPI9807312B8 (de) |
| CA (1) | CA2281702C (de) |
| CY (1) | CY2324B1 (de) |
| DE (1) | DE69812980T2 (de) |
| DK (1) | DK1015446T3 (de) |
| ES (1) | ES2194303T3 (de) |
| HU (1) | HUP0001308A3 (de) |
| IL (1) | IL131243A (de) |
| NO (1) | NO318936B1 (de) |
| NZ (1) | NZ336719A (de) |
| PT (1) | PT1015446E (de) |
| TW (1) | TW518333B (de) |
| WO (1) | WO1998034933A1 (de) |
| ZA (1) | ZA98831B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2342083T3 (es) * | 2004-04-29 | 2010-07-01 | Aventis Pharmaceuticals Inc. | 3-piperidinilisocroman-5-oles como agonistas de dopamina. |
| CN102210663B (zh) | 2004-05-28 | 2013-07-31 | 尤尼根公司 | 作为双核酶强效抑制剂的二芳基烷烃 |
| ES2498673T3 (es) | 2007-07-26 | 2014-09-25 | F. Hoffmann-La Roche Ag | Moduladores duales de los receptores 5-HT2a y D3 |
| AU2009274158C1 (en) | 2008-07-21 | 2019-09-05 | Unigen, Inc. | Series of skin-whitening (lightening) compounds |
| US8877778B2 (en) | 2010-12-15 | 2014-11-04 | Hoffmann-La Roche Inc. | Benzofurane compounds |
| CN102079720B (zh) * | 2011-01-20 | 2013-02-06 | 蚌埠丰原医药科技发展有限公司 | 一种制备1-苄基-4-哌啶甲醛的方法 |
| CN109180448A (zh) | 2011-03-24 | 2019-01-11 | 尤尼根公司 | 用于制备二芳基丙烷的化合物和方法 |
| US8921397B2 (en) | 2011-05-04 | 2014-12-30 | Hoffmann-La Roche Inc. | Benzofurane-piperidine compounds |
| CN117924153A (zh) * | 2024-01-11 | 2024-04-26 | 山东盛安贝新材料有限公司南京分公司 | 一种多奈哌齐原料药关键中间体的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
| US4963568A (en) * | 1989-05-31 | 1990-10-16 | Abbott Laboratories | Dopamine agonists |
-
1998
- 1998-01-20 ES ES98902628T patent/ES2194303T3/es not_active Expired - Lifetime
- 1998-01-20 CN CN98802357A patent/CN1092653C/zh not_active Expired - Lifetime
- 1998-01-20 EP EP98902628A patent/EP1015446B1/de not_active Expired - Lifetime
- 1998-01-20 WO PCT/US1998/000979 patent/WO1998034933A1/en not_active Ceased
- 1998-01-20 IL IL13124398A patent/IL131243A/en not_active IP Right Cessation
- 1998-01-20 BR BRPI9807312A patent/BRPI9807312B8/pt not_active IP Right Cessation
- 1998-01-20 DK DK98902628T patent/DK1015446T3/da active
- 1998-01-20 KR KR10-1999-7007127A patent/KR100509878B1/ko not_active Expired - Fee Related
- 1998-01-20 AT AT98902628T patent/ATE236150T1/de active
- 1998-01-20 JP JP53461798A patent/JP4177461B2/ja not_active Expired - Fee Related
- 1998-01-20 DE DE69812980T patent/DE69812980T2/de not_active Expired - Lifetime
- 1998-01-20 PT PT98902628T patent/PT1015446E/pt unknown
- 1998-01-20 AU AU59237/98A patent/AU725301B2/en not_active Expired
- 1998-01-20 NZ NZ336719A patent/NZ336719A/xx unknown
- 1998-01-20 HU HU0001308A patent/HUP0001308A3/hu unknown
- 1998-01-20 CA CA002281702A patent/CA2281702C/en not_active Expired - Lifetime
- 1998-02-02 ZA ZA98831A patent/ZA98831B/xx unknown
- 1998-02-03 TW TW087101327A patent/TW518333B/zh not_active IP Right Cessation
- 1998-02-03 AR ARP980100456A patent/AR011614A1/es active IP Right Grant
-
1999
- 1999-08-06 NO NO19993812A patent/NO318936B1/no unknown
-
2003
- 2003-04-30 CY CY0300037A patent/CY2324B1/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4177461B2 (ja) | 2008-11-05 |
| ZA98831B (en) | 1998-08-07 |
| BR9807312A (pt) | 2000-05-02 |
| AR011614A1 (es) | 2000-08-30 |
| NO318936B1 (no) | 2005-05-30 |
| ES2194303T3 (es) | 2003-11-16 |
| BRPI9807312B8 (pt) | 2016-09-13 |
| CN1092653C (zh) | 2002-10-16 |
| HUP0001308A2 (hu) | 2001-06-28 |
| IL131243A (en) | 2004-02-19 |
| KR20000070862A (ko) | 2000-11-25 |
| HUP0001308A3 (en) | 2001-07-30 |
| DE69812980D1 (de) | 2003-05-08 |
| WO1998034933A1 (en) | 1998-08-13 |
| BR9807312B1 (pt) | 2013-10-29 |
| DK1015446T3 (da) | 2003-07-14 |
| NO993812D0 (no) | 1999-08-06 |
| EP1015446A1 (de) | 2000-07-05 |
| HK1027812A1 (en) | 2001-01-23 |
| AU5923798A (en) | 1998-08-26 |
| NZ336719A (en) | 2000-10-27 |
| DE69812980T2 (de) | 2003-11-13 |
| TW518333B (en) | 2003-01-21 |
| PT1015446E (pt) | 2003-08-29 |
| IL131243A0 (en) | 2001-01-28 |
| CN1246859A (zh) | 2000-03-08 |
| AU725301B2 (en) | 2000-10-12 |
| EP1015446B1 (de) | 2003-04-02 |
| CA2281702A1 (en) | 1998-08-13 |
| KR100509878B1 (ko) | 2005-08-25 |
| CA2281702C (en) | 2006-04-11 |
| CY2324B1 (en) | 2003-11-14 |
| NO993812L (no) | 1999-10-05 |
| JP2001512436A (ja) | 2001-08-21 |
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| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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