DK1019521T3 - Fremgangsmåde til biotransformation af colchiconforbindelser til de tilsvarende 3-glycosylderivater - Google Patents

Fremgangsmåde til biotransformation af colchiconforbindelser til de tilsvarende 3-glycosylderivater

Info

Publication number
DK1019521T3
DK1019521T3 DK98952675T DK98952675T DK1019521T3 DK 1019521 T3 DK1019521 T3 DK 1019521T3 DK 98952675 T DK98952675 T DK 98952675T DK 98952675 T DK98952675 T DK 98952675T DK 1019521 T3 DK1019521 T3 DK 1019521T3
Authority
DK
Denmark
Prior art keywords
biotransformation
compounds
glycosyl derivatives
colchicone
colchicone compounds
Prior art date
Application number
DK98952675T
Other languages
Danish (da)
English (en)
Inventor
Ezio Bombardelli
Cesare Ponzone
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1019521T3 publication Critical patent/DK1019521T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/56Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK98952675T 1997-10-03 1998-09-30 Fremgangsmåde til biotransformation af colchiconforbindelser til de tilsvarende 3-glycosylderivater DK1019521T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI002255A IT1295272B1 (it) 1997-10-03 1997-10-03 Biotrasformazione di composti colchiconici nei corrispondenti 3- glicosilderivati

Publications (1)

Publication Number Publication Date
DK1019521T3 true DK1019521T3 (da) 2006-10-02

Family

ID=11377985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98952675T DK1019521T3 (da) 1997-10-03 1998-09-30 Fremgangsmåde til biotransformation af colchiconforbindelser til de tilsvarende 3-glycosylderivater

Country Status (20)

Country Link
US (1) US6372458B1 (fr)
EP (1) EP1019521B1 (fr)
KR (1) KR100536676B1 (fr)
CN (1) CN1188527C (fr)
AT (1) ATE328106T1 (fr)
AU (1) AU745222B2 (fr)
CA (1) CA2305046C (fr)
CZ (1) CZ295749B6 (fr)
DE (1) DE69834736T2 (fr)
DK (1) DK1019521T3 (fr)
ES (1) ES2264214T3 (fr)
HU (1) HU225686B1 (fr)
IL (1) IL134566A (fr)
IT (1) IT1295272B1 (fr)
NO (1) NO320096B1 (fr)
PL (1) PL190865B1 (fr)
PT (1) PT1019521E (fr)
RU (1) RU2218409C2 (fr)
SK (1) SK285923B6 (fr)
WO (1) WO1999018229A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040175782A1 (en) * 2003-03-06 2004-09-09 Tethys Research Llc Biotransformation of compounds using non-prokaryotic microalgae
CN1954081B (zh) * 2004-05-12 2012-07-18 因德纳有限公司 类秋水仙碱化合物的生物转化
US8795986B2 (en) * 2010-09-22 2014-08-05 Sequent Scientific Ltd. Microbial method for the biotransformation of colchicinoid compounds
WO2015097567A1 (fr) 2013-12-23 2015-07-02 Alkaloids Corporation Procédé pour la conversion de colchicinoïdes en leurs dérivés 3-glycosylés par leur analogues 3-déméthyl correspondants
CN105861601B (zh) * 2016-04-29 2019-05-24 中国药科大学 一种生物转化制备二氢去氢双松柏醇葡萄糖单糖苷(hmzg)的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1344157A (fr) * 1959-05-22 1963-11-29 Roussel Uclaf Nouvelles colchicines et leur procédé d'obtention
US3442953A (en) * 1963-06-19 1969-05-06 Roussel Uclaf Novel 7-oxo-7-desacetylaminocolchicine compounds
JPS5233195B2 (fr) * 1971-09-30 1977-08-26
IT1285777B1 (it) * 1996-10-07 1998-06-18 Indena Spa Processo di biotrasformazione di composti colchicinoidi nei corrispondenti 3-glicosilderivati

Also Published As

Publication number Publication date
IT1295272B1 (it) 1999-05-04
DE69834736D1 (de) 2006-07-06
HUP0004840A2 (hu) 2001-04-28
NO20001706D0 (no) 2000-04-03
KR20010030710A (ko) 2001-04-16
NO20001706L (no) 2000-06-05
HU225686B1 (en) 2007-06-28
SK4832000A3 (en) 2000-09-12
PT1019521E (pt) 2006-09-29
CA2305046A1 (fr) 1999-04-15
CN1188527C (zh) 2005-02-09
DE69834736T2 (de) 2007-05-10
HK1031896A1 (en) 2001-06-29
AU1028399A (en) 1999-04-27
CZ295749B6 (cs) 2005-10-12
EP1019521B1 (fr) 2006-05-31
NO320096B1 (no) 2005-10-24
RU2218409C2 (ru) 2003-12-10
WO1999018229A1 (fr) 1999-04-15
HUP0004840A3 (en) 2002-10-28
KR100536676B1 (ko) 2005-12-14
CA2305046C (fr) 2008-12-09
PL339620A1 (en) 2001-01-02
SK285923B6 (sk) 2007-11-02
EP1019521A1 (fr) 2000-07-19
IL134566A0 (en) 2001-04-30
IL134566A (en) 2004-06-20
CZ20001196A3 (cs) 2000-10-11
ATE328106T1 (de) 2006-06-15
PL190865B1 (pl) 2006-02-28
ES2264214T3 (es) 2006-12-16
CN1273607A (zh) 2000-11-15
US6372458B1 (en) 2002-04-16
AU745222B2 (en) 2002-03-14
ITMI972255A1 (it) 1999-04-03

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