DK1025114T3 - 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet - Google Patents

3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet

Info

Publication number
DK1025114T3
DK1025114T3 DK98946087T DK98946087T DK1025114T3 DK 1025114 T3 DK1025114 T3 DK 1025114T3 DK 98946087 T DK98946087 T DK 98946087T DK 98946087 T DK98946087 T DK 98946087T DK 1025114 T3 DK1025114 T3 DK 1025114T3
Authority
DK
Denmark
Prior art keywords
modified
antibacterial activity
substituted erythromycin
ketolide derivatives
erythromycin ketolide
Prior art date
Application number
DK98946087T
Other languages
English (en)
Inventor
Yat Sun Or
Zhenkun Ma
Daniel T Chu
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of DK1025114T3 publication Critical patent/DK1025114T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
DK98946087T 1997-09-30 1998-09-16 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet DK1025114T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US94087197A 1997-09-30 1997-09-30
US13312198A 1998-08-12 1998-08-12
PCT/US1998/019311 WO1999016779A1 (en) 1997-09-30 1998-09-16 3'-n-modified 6-o-substituted erythromycin ketolide derivatives having antibacterial activity

Publications (1)

Publication Number Publication Date
DK1025114T3 true DK1025114T3 (da) 2004-07-05

Family

ID=26831064

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98946087T DK1025114T3 (da) 1997-09-30 1998-09-16 3'-N-modificerede 6-O-substituerede erythromycin-ketolidderivater med antibakteriel aktivitet

Country Status (22)

Country Link
EP (1) EP1025114B1 (da)
JP (1) JP2001518476A (da)
KR (1) KR20010030807A (da)
CN (1) CN1271363A (da)
AR (1) AR015727A1 (da)
AT (1) ATE260293T1 (da)
AU (1) AU737310B2 (da)
BG (1) BG104340A (da)
BR (1) BR9812577A (da)
CA (1) CA2303930A1 (da)
CO (1) CO4990958A1 (da)
DE (1) DE69821964T2 (da)
DK (1) DK1025114T3 (da)
ES (1) ES2217579T3 (da)
HU (1) HUP0004579A3 (da)
IL (1) IL134608A0 (da)
NO (1) NO20001439L (da)
PL (1) PL339575A1 (da)
PT (1) PT1025114E (da)
SK (1) SK4562000A3 (da)
TR (1) TR200000805T2 (da)
WO (1) WO1999016779A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
US6395710B1 (en) * 1999-04-16 2002-05-28 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6355620B1 (en) * 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
US6437106B1 (en) * 1999-06-24 2002-08-20 Abbott Laboratories Process for preparing 6-o-substituted erythromycin derivatives
CA2417319A1 (en) * 2000-08-14 2003-01-27 Taisho Pharmaceutical Co., Ltd. Process for producing erythromycin derivative
US20020111317A1 (en) * 2000-09-25 2002-08-15 Leonard Katz Sixteen-membered macrolide compounds
ITMI20021726A1 (it) 2002-08-01 2004-02-02 Zambon Spa Macrolidi ad attivita' antiinfiammatoria.
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
CN108101948A (zh) * 2004-02-27 2018-06-01 瑞伯-X医药品有限公司 大环化合物以及其制作和使用方法
EP2716647A3 (en) * 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same
RU2397987C2 (ru) * 2004-07-28 2010-08-27 Рэнбакси Лабораториз Лимитед Кетолидные производные в качестве антибактериальных агентов
US20090170790A1 (en) * 2004-10-25 2009-07-02 Biswajit Das Ketolide derivatives as antibacterial agents
WO2006129257A2 (en) * 2005-05-30 2006-12-07 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
JP2009506066A (ja) 2005-08-24 2009-02-12 リブ−エックス ファーマシューティカルズ，インコーポレイテッド トリアゾール化合物ならびにこれを作製する方法および使用する方法
US8470985B2 (en) 2005-08-24 2013-06-25 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
EP1957508A2 (en) * 2005-11-23 2008-08-20 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
EP2077271A4 (en) * 2006-05-01 2010-09-15 Taisho Pharmaceutical Co Ltd Macrolide derivative
WO2008099368A1 (en) * 2007-02-15 2008-08-21 Ranbaxy Laboratories Limited Macrolide derivatives as antibacterial agents
WO2008111020A2 (en) * 2007-03-14 2008-09-18 Ranbaxy Laboratories Limited Macrolide derivatives as antibacterial agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
ES2218604T3 (es) * 1995-11-08 2004-11-16 Abbott Laboratories Derivados triciclicos de eritromicina.

Also Published As

Publication number Publication date
CO4990958A1 (es) 2000-12-26
JP2001518476A (ja) 2001-10-16
AU737310B2 (en) 2001-08-16
BG104340A (en) 2001-01-31
TR200000805T2 (tr) 2000-10-23
AR015727A1 (es) 2001-05-16
DE69821964D1 (de) 2004-04-01
HUP0004579A3 (en) 2001-11-28
ATE260293T1 (de) 2004-03-15
NO20001439D0 (no) 2000-03-20
EP1025114A1 (en) 2000-08-09
EP1025114B1 (en) 2004-02-25
BR9812577A (pt) 2000-10-17
NO20001439L (no) 2000-05-29
IL134608A0 (en) 2001-04-30
ES2217579T3 (es) 2004-11-01
CN1271363A (zh) 2000-10-25
SK4562000A3 (en) 2000-09-12
PL339575A1 (en) 2000-12-18
PT1025114E (pt) 2004-07-30
DE69821964T2 (de) 2004-12-30
WO1999016779A1 (en) 1999-04-08
KR20010030807A (ko) 2001-04-16
HUP0004579A2 (hu) 2001-05-28
CA2303930A1 (en) 1999-04-08
AU9317698A (en) 1999-04-23

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