ATE260293T1 - 3'-n-modifizierte 6-0 substituierte erythromycin ketolide derivate mit antibakterieller wirkung - Google Patents

3'-n-modifizierte 6-0 substituierte erythromycin ketolide derivate mit antibakterieller wirkung

Info

Publication number: ATE260293T1
Authority: AT; Austria
Prior art keywords: modified; antibacterial action; substituted erythromycin; ketolide derivatives; erythromycin ketolide
Prior art date: 1997-09-30

Application number

AT98946087T

Other languages

English (en)

Inventor

Yat Sun Or

Zhenkun Ma

Daniel T Chu

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-30

Filing date

1998-09-16

Publication date

2004-03-15

1998-09-16 Application filed by Abbott Lab filed Critical Abbott Lab

2004-03-15 Application granted granted Critical

2004-03-15 Publication of ATE260293T1 publication Critical patent/ATE260293T1/de

Links

ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical class O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 title 2
230000000844 anti-bacterial effect Effects 0.000 title 1
229960003276 erythromycin Drugs 0.000 title 1
239000003835 ketolide antibiotic agent Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)

AT98946087T 1997-09-30 1998-09-16 3'-n-modifizierte 6-0 substituierte erythromycin ketolide derivate mit antibakterieller wirkung ATE260293T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US94087197A	1997-09-30	1997-09-30
US13312198A	1998-08-12	1998-08-12
PCT/US1998/019311 WO1999016779A1 (en)	1997-09-30	1998-09-16	3'-n-modified 6-o-substituted erythromycin ketolide derivatives having antibacterial activity

Publications (1)

Publication Number	Publication Date
ATE260293T1 true ATE260293T1 (de)	2004-03-15

Family

ID=26831064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98946087T ATE260293T1 (de)	1997-09-30	1998-09-16	3'-n-modifizierte 6-0 substituierte erythromycin ketolide derivate mit antibakterieller wirkung

Country Status (22)

Country	Link
EP (1)	EP1025114B1 (de)
JP (1)	JP2001518476A (de)
KR (1)	KR20010030807A (de)
CN (1)	CN1271363A (de)
AR (1)	AR015727A1 (de)
AT (1)	ATE260293T1 (de)
AU (1)	AU737310B2 (de)
BG (1)	BG104340A (de)
BR (1)	BR9812577A (de)
CA (1)	CA2303930A1 (de)
CO (1)	CO4990958A1 (de)
DE (1)	DE69821964T2 (de)
DK (1)	DK1025114T3 (de)
ES (1)	ES2217579T3 (de)
HU (1)	HUP0004579A3 (de)
IL (1)	IL134608A0 (de)
NO (1)	NO20001439L (de)
PL (1)	PL339575A1 (de)
PT (1)	PT1025114E (de)
SK (1)	SK4562000A3 (de)
TR (1)	TR200000805T2 (de)
WO (1)	WO1999016779A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4573925B2 (ja) *	1998-07-09	2010-11-04	アベンティス・ファーマ・ソシエテ・アノニム	新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
AU775637B2 (en) *	1999-04-16	2004-08-12	Kosan Biosciences, Inc.	Macrolide antiinfective agents
US6355620B1 (en) *	1999-05-14	2002-03-12	Abbott Laboratories	C-2 modified erythromycin derivatives
US6437106B1 (en)	1999-06-24	2002-08-20	Abbott Laboratories	Process for preparing 6-o-substituted erythromycin derivatives
AU2001277764A1 (en) *	2000-08-14	2002-02-25	Taisho Pharmaceutical Co., Ltd.	Process for producing erythromycin derivative
US20020128213A1 (en) *	2000-09-25	2002-09-12	Leonard Katz	Sixteen-membered macrolide compounds
ITMI20021726A1 (it)	2002-08-01	2004-02-02	Zambon Spa	Macrolidi ad attivita' antiinfiammatoria.
US7091196B2 (en)	2002-09-26	2006-08-15	Rib-X Pharmaceuticals, Inc.	Bifunctional heterocyclic compounds and methods of making and using same
CN1950388A (zh) *	2004-02-27	2007-04-18	瑞伯-X医药品有限公司	大环化合物以及其制作和使用方法
EP2716647A3 (de) *	2004-02-27	2014-08-20	Rib-X Pharmaceuticals, Inc.	Makrocyclische Verbindungen Und Verfahren Zu Deren Herstellung Und Anwendung
WO2006080954A1 (en) *	2004-07-28	2006-08-03	Ranbaxy Laboratories Limited	Ketolide derivatives as antibacterial agents
WO2006046112A2 (en) *	2004-10-25	2006-05-04	Ranbaxy Laboratories Limited	Ketolide derivatives as antibacterial agents
WO2006129257A2 (en) *	2005-05-30	2006-12-07	Ranbaxy Laboratories Limited	Ketolide derivatives as antibacterial agents
EP1934237A2 (de)	2005-08-24	2008-06-25	Rib-X Pharmaceuticals, Inc.	Triazolverbindungen und verfahren zu deren herstellung und anwendung
EP1928893A2 (de)	2005-08-24	2008-06-11	Rib-X Pharmaceuticals, Inc.	Triazolverbindungen und verfahren zu ihrer herstellung und verwendung
WO2007060518A2 (en) *	2005-11-23	2007-05-31	Ranbaxy Laboratories Limited	Ketolide derivatives as antibacterial agents
JP5126685B2 (ja) *	2006-05-01	2013-01-23	大正製薬株式会社	マクロライド誘導体
WO2008099368A1 (en) *	2007-02-15	2008-08-21	Ranbaxy Laboratories Limited	Macrolide derivatives as antibacterial agents
WO2008111020A2 (en) *	2007-03-14	2008-09-18	Ranbaxy Laboratories Limited	Macrolide derivatives as antibacterial agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL99995A (en) *	1990-11-21	1997-11-20	Roussel Uclaf	Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
PT876388E (pt) *	1995-11-08	2004-07-30	Abbott Lab	Derivados de eritromicina triciclica

1998
- 1998-09-16 CA CA002303930A patent/CA2303930A1/en not_active Abandoned
- 1998-09-16 ES ES98946087T patent/ES2217579T3/es not_active Expired - Lifetime
- 1998-09-16 EP EP98946087A patent/EP1025114B1/de not_active Expired - Lifetime
- 1998-09-16 AU AU93176/98A patent/AU737310B2/en not_active Ceased
- 1998-09-16 CN CN98809567A patent/CN1271363A/zh active Pending
- 1998-09-16 AT AT98946087T patent/ATE260293T1/de not_active IP Right Cessation
- 1998-09-16 JP JP2000513861A patent/JP2001518476A/ja not_active Withdrawn
- 1998-09-16 DK DK98946087T patent/DK1025114T3/da active
- 1998-09-16 TR TR2000/00805T patent/TR200000805T2/xx unknown
- 1998-09-16 IL IL13460898A patent/IL134608A0/xx unknown
- 1998-09-16 SK SK456-2000A patent/SK4562000A3/sk unknown
- 1998-09-16 PL PL98339575A patent/PL339575A1/xx unknown
- 1998-09-16 BR BR9812577-0A patent/BR9812577A/pt not_active IP Right Cessation
- 1998-09-16 PT PT98946087T patent/PT1025114E/pt unknown
- 1998-09-16 DE DE69821964T patent/DE69821964T2/de not_active Expired - Fee Related
- 1998-09-16 KR KR1020007003408A patent/KR20010030807A/ko not_active Withdrawn
- 1998-09-16 HU HU0004579A patent/HUP0004579A3/hu unknown
- 1998-09-16 WO PCT/US1998/019311 patent/WO1999016779A1/en not_active Ceased
- 1998-09-28 CO CO98056259A patent/CO4990958A1/es unknown
- 1998-09-29 AR ARP980104856A patent/AR015727A1/es unknown
2000
- 2000-03-20 NO NO20001439A patent/NO20001439L/no not_active Application Discontinuation
- 2000-04-14 BG BG104340A patent/BG104340A/xx unknown

Also Published As

Publication number	Publication date
AR015727A1 (es)	2001-05-16
IL134608A0 (en)	2001-04-30
ES2217579T3 (es)	2004-11-01
KR20010030807A (ko)	2001-04-16
DK1025114T3 (da)	2004-07-05
CA2303930A1 (en)	1999-04-08
DE69821964D1 (de)	2004-04-01
NO20001439D0 (no)	2000-03-20
CN1271363A (zh)	2000-10-25
HUP0004579A3 (en)	2001-11-28
BR9812577A (pt)	2000-10-17
SK4562000A3 (en)	2000-09-12
NO20001439L (no)	2000-05-29
DE69821964T2 (de)	2004-12-30
EP1025114A1 (de)	2000-08-09
BG104340A (en)	2001-01-31
PL339575A1 (en)	2000-12-18
PT1025114E (pt)	2004-07-30
HUP0004579A2 (hu)	2001-05-28
AU737310B2 (en)	2001-08-16
WO1999016779A1 (en)	1999-04-08
JP2001518476A (ja)	2001-10-16
TR200000805T2 (tr)	2000-10-23
AU9317698A (en)	1999-04-23
EP1025114B1 (de)	2004-02-25
CO4990958A1 (es)	2000-12-26

Legal Events

Date

Code

Title

Description

2004-10-15

UEP

Publication of translation of european patent specification

Ref document number: 1025114

Country of ref document: EP

2010-06-15

REN

Ceased due to non-payment of the annual fee

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DE69934805D1 (de)	2007-02-22	Substituierte imidazole mit cytokin-inhibierender wirkung
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DE69927008D1 (de)	2005-10-06	Verbindungen mit kalzilytischer wirkung
ATE257484T1 (de)	2004-01-15	6,9-verbrückte erythromycin-derivate
ATE298760T1 (de)	2005-07-15	2-halo-6-0-substituierte ketolide derivate
ATE239750T1 (de)	2003-05-15	6,11-verbrückte erythromycinderivate
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