DK1028744T3 - Neuronale anvendelser af BMP-11 - Google Patents

Neuronale anvendelser af BMP-11

Info

Publication number
DK1028744T3
DK1028744T3 DK98957711T DK98957711T DK1028744T3 DK 1028744 T3 DK1028744 T3 DK 1028744T3 DK 98957711 T DK98957711 T DK 98957711T DK 98957711 T DK98957711 T DK 98957711T DK 1028744 T3 DK1028744 T3 DK 1028744T3
Authority
DK
Denmark
Prior art keywords
bmp
proteins
useful
disclosed
neuronal
Prior art date
Application number
DK98957711T
Other languages
Danish (da)
English (en)
Inventor
Anthony J Celeste
John M Wozney
Scott R Thies
Original Assignee
Inst Genetics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Genetics Llc filed Critical Inst Genetics Llc
Application granted granted Critical
Publication of DK1028744T3 publication Critical patent/DK1028744T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0619—Neurons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98957711T 1997-11-07 1998-11-06 Neuronale anvendelser af BMP-11 DK1028744T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96629797A 1997-11-07 1997-11-07
PCT/US1998/023827 WO1999024058A2 (fr) 1997-11-07 1998-11-06 Utilisations neuronales de bmp-11

Publications (1)

Publication Number Publication Date
DK1028744T3 true DK1028744T3 (da) 2004-06-21

Family

ID=25511184

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98957711T DK1028744T3 (da) 1997-11-07 1998-11-06 Neuronale anvendelser af BMP-11

Country Status (10)

Country Link
EP (1) EP1028744B1 (fr)
JP (1) JP2001522810A (fr)
AT (1) ATE259652T1 (fr)
AU (2) AU1276399A (fr)
CA (1) CA2309538A1 (fr)
DE (1) DE69821793T2 (fr)
DK (1) DK1028744T3 (fr)
ES (1) ES2213927T3 (fr)
PT (1) PT1028744E (fr)
WO (2) WO1999024057A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104977A1 (en) * 2000-03-31 2003-06-05 Ugo Ripamonti Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors
TWI329129B (en) * 2001-02-08 2010-08-21 Wyeth Corp Modified and stabilized gdf propeptides and uses thereof
US20040259779A1 (en) * 2001-07-06 2004-12-23 Teit Johansen Novel neurotrophic factors
US7320789B2 (en) 2001-09-26 2008-01-22 Wyeth Antibody inhibitors of GDF-8 and uses thereof
BR0307871A (pt) 2002-02-21 2005-04-12 Wyeth Corp Proteìnas contendo domìnio de folistatina
CA2476887A1 (fr) 2002-02-21 2003-09-04 Wyeth Proteine contenant un domaine de follistatine
AR047392A1 (es) 2002-10-22 2006-01-18 Wyeth Corp Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
CA2518102C (fr) 2003-03-04 2009-05-12 Tanabe Seiyaku Co., Ltd. Preparation en poudre pour l'administration nasale
BRPI0410927A (pt) 2003-06-02 2006-06-27 Wyeth Corp métodos terapêuticos e profiláticos para distúrbios neuromusculares
BRPI0616923A2 (pt) 2005-10-06 2011-07-05 Lilly Co Eli anticorpos monoclonais, seus usos e composição farmacêutica
UA92504C2 (en) 2005-10-12 2010-11-10 Эли Лилли Энд Компани Anti-myostatin monoclonal antibody
CA2661836A1 (fr) 2006-09-05 2008-03-13 Eli Lilly And Company Anticorps anti-myostatine
EP2983694B1 (fr) 2013-04-08 2022-06-22 President and Fellows of Harvard College Compositions pour rajeunir des cellules souches de muscle squelettique
EP3881859B1 (fr) * 2013-06-11 2024-03-06 President and Fellows of Harvard College Compositions pour augmenter la neurogenèse et l'angiogenèse
WO2015070076A2 (fr) * 2013-11-08 2015-05-14 President And Fellows Of Harvard College Procédés et compositions permettant de régénérer des jonctions neuromusculaires
CA3010799A1 (fr) 2016-01-06 2017-07-13 President And Fellows Of Harvard College Un traitement par le gdf11 previent la prise de poids, ameliore la tolerance au glucose, et diminue la steatose hepatique
WO2019144053A1 (fr) * 2018-01-19 2019-07-25 President And Fellows Of Harward College Variants de gdf11 et leurs utilisations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9406715A (pt) * 1993-05-12 1996-02-06 Genetics Inst Molécula de DNA isolada célula hospedeira vetor método para produzir uma proteina (BMP-11) polipeptideo de proteina-11 morfogenética de osso purificada (BMP-11) e molécula de DNA quimérica
SE9302550D0 (sv) * 1993-07-30 1993-07-30 Ernst Hoerlin Powder inhaler
DK0716610T3 (da) * 1993-08-26 2006-09-04 Genetics Inst Llc Humane knogle-morfogenetiske proteiner til anvendelse ved neural regenerering
CA2194660C (fr) * 1994-07-08 2009-09-29 Se-Jin Lee Facteur 11 de differentiation de croissance

Also Published As

Publication number Publication date
DE69821793D1 (de) 2004-03-25
EP1028744A2 (fr) 2000-08-23
JP2001522810A (ja) 2001-11-20
CA2309538A1 (fr) 1999-05-20
AU1390099A (en) 1999-05-31
EP1028744B1 (fr) 2004-02-18
WO1999024058A2 (fr) 1999-05-20
ES2213927T3 (es) 2004-09-01
PT1028744E (pt) 2004-06-30
WO1999024058A3 (fr) 1999-08-19
ATE259652T1 (de) 2004-03-15
AU761940B2 (en) 2003-06-12
AU1276399A (en) 1999-05-31
WO1999024057A2 (fr) 1999-05-20
DE69821793T2 (de) 2004-12-30

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