DK106388A - Ethynylcyclohexenderivater - Google Patents
EthynylcyclohexenderivaterInfo
- Publication number
- DK106388A DK106388A DK106388A DK106388A DK106388A DK 106388 A DK106388 A DK 106388A DK 106388 A DK106388 A DK 106388A DK 106388 A DK106388 A DK 106388A DK 106388 A DK106388 A DK 106388A
- Authority
- DK
- Denmark
- Prior art keywords
- formula
- compound
- image
- zeaxanthine
- converted
- Prior art date
Links
- DKFHWNGVMWFBJE-UHFFFAOYSA-N 1-ethynylcyclohexene Chemical class C#CC1=CCCCC1 DKFHWNGVMWFBJE-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000004703 alkoxides Chemical class 0.000 abstract 2
- JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 abstract 2
- FUSUHKVFWTUUBE-UHFFFAOYSA-N buten-2-one Chemical compound CC(=O)C=C FUSUHKVFWTUUBE-UHFFFAOYSA-N 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- JKQXZKUSFCKOGQ-QAYBQHTQSA-N zeaxanthin Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-QAYBQHTQSA-N 0.000 abstract 2
- 125000000027 (C1-C10) alkoxy group Chemical group 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 abstract 1
- 229910000091 aluminium hydride Inorganic materials 0.000 abstract 1
- BLRXYTIIKIPJQL-UHFFFAOYSA-N dicarbide(1-) Chemical compound [C-]#C BLRXYTIIKIPJQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic
- C07C35/08—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings
- C07C35/17—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring monocyclic containing a six-membered rings with unsaturation only outside the ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5435—Cycloaliphatic phosphonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Glass Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH119187 | 1987-03-27 | ||
| CH119187 | 1987-03-27 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK106388D0 DK106388D0 (da) | 1988-02-29 |
| DK106388A true DK106388A (da) | 1988-09-28 |
| DK171297B1 DK171297B1 (da) | 1996-08-26 |
Family
ID=4204633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK106388A DK171297B1 (da) | 1987-03-27 | 1988-02-29 | Fremgangsmåde til fremstilling af cyclohexenderivater som mellemprodukter til fremstilling af zeaxanthin samt cyclohexenderivater |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4952716A (da) |
| EP (1) | EP0283979B1 (da) |
| JP (1) | JP2542667B2 (da) |
| AT (1) | ATE80385T1 (da) |
| DE (1) | DE3874378D1 (da) |
| DK (1) | DK171297B1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5625015A (en) | 1994-11-23 | 1997-04-29 | Exxon Chemical Patents Inc. | Method for making supported catalyst systems and catalyst systems therefrom |
| DE19509955A1 (de) * | 1995-03-18 | 1996-09-19 | Basf Ag | Verfahren zur Herstellung von Astaxanthin |
| CA2225493A1 (en) | 1995-08-10 | 1997-02-20 | Exxon Chemical Patents, Inc. | Metallocene stabilized alumoxane |
| US5652202A (en) * | 1995-08-15 | 1997-07-29 | Exxon Chemical Patents Inc. | Lubricating oil compositions |
| US5558802A (en) * | 1995-09-14 | 1996-09-24 | Exxon Chemical Patents Inc | Multigrade crankcase lubricants with low temperature pumpability and low volatility |
| US5747544A (en) * | 1995-10-31 | 1998-05-05 | Applied Food Biotechnology, Inc. | Method of using pure 3R-3'R stereoisomer of zeaxanthin to treat or prevent retinal degeneration in humans |
| US5854015A (en) * | 1995-10-31 | 1998-12-29 | Applied Food Biotechnology, Inc. | Method of making pure 3R-3'R stereoisomer of zeaxanthin for human ingestion |
| CA2188983C (en) | 1995-10-31 | 2001-02-27 | Kevin M. Garnett | Pure 3r-3'r stereoisomer of zeaxanthin for treating macular degeneration in humans |
| US5827652A (en) * | 1995-10-31 | 1998-10-27 | Applied Food Biotechnology, Inc. | Zeaxanthin formulations for human ingestion |
| DE19723480A1 (de) * | 1997-06-04 | 1998-12-10 | Basf Ag | Verfahren zur Herstellung von Zeaxanthin, Zwischenprodukte für dieses Verfahren und Verfahren zu deren Herstellung |
| US7691406B2 (en) * | 2000-10-27 | 2010-04-06 | ZeaVision LLC. | Zeaxanthin formulations for human ingestion |
| DE10145223A1 (de) * | 2001-09-13 | 2003-04-03 | Basf Ag | Verfahren zur Herstellung von meso-Zeaxanthin |
| US7320997B2 (en) * | 2002-07-29 | 2008-01-22 | Cardax Pharmaceuticals, Inc. | Pharmaceutical compositions including carotenoid ester analogs or derivatives for the inhibition and amelioration of disease |
| CN101845009B (zh) * | 2002-07-29 | 2012-10-03 | 卡达克斯药物公司 | 用于抑制和改善疾病的类胡萝卜素结构类似物 |
| US8088363B2 (en) | 2002-10-28 | 2012-01-03 | Zeavision Llc | Protection against sunburn and skin problems with orally-ingested high-dosage zeaxanthin |
| US9192586B2 (en) | 2003-03-10 | 2015-11-24 | Zeavision Llc | Zeaxanthin formulations with additional ocular-active nutrients, for protecting eye health and treating eye disorders |
| US20070082066A1 (en) * | 2003-05-07 | 2007-04-12 | Gierhart Dennis L | Use of zeaxanthin to reduce light hyper-sensitivity, photophobia, and medical conditions relating to light hyper-sensitivity |
| US7541166B2 (en) * | 2003-09-19 | 2009-06-02 | Microfluidic Systems, Inc. | Sonication to selectively lyse different cell types |
| US7941211B2 (en) * | 2003-11-17 | 2011-05-10 | Zeavision, Llc. | Preloading with macular pigment to improve photodynamic treatment of retinal vascular disorders |
| US20060089411A1 (en) * | 2004-08-07 | 2006-04-27 | Gierhart Dennis L | Treatment of Stargardt's disease and other lipofuscin disorders with combined retinaldehyde inhibitor and zeaxanthin |
| WO2006039685A2 (en) * | 2004-10-01 | 2006-04-13 | Hawaii Biotech, Inc. | Methods for synthesis of chiral intermediates of carotenoids, carotenoid analogs, and carotenoid derivatives |
| US8592662B2 (en) | 2005-02-11 | 2013-11-26 | Kalamazoo Holdings, Inc. | Capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom |
| EP1861078A2 (en) * | 2005-02-11 | 2007-12-05 | Kalamazoo Holdings, Inc. | A capsicum variety exhibiting a hyper-accumulation of zeaxanthin and products derived therefrom |
| WO2008003737A1 (de) * | 2006-07-07 | 2008-01-10 | Basf Se | Verfahren zur herstellung von 3,3'-dihydroxyisorenieratin sowie neue zwischenprodukte hierfür |
| ES2583004T3 (es) | 2010-10-13 | 2016-09-16 | Vigenent Inc. | Olleya marilimosa y su uso en un método para la preparación de una composición que contiene zeaxantina |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1046612B (de) * | 1957-10-23 | 1958-12-18 | Basf Ag | Verfahren zur Herstellung von Vitamin A und seinen biologisch wirksamen Derivaten |
| BE754225A (fr) * | 1969-08-01 | 1971-02-01 | Hoffmann La Roche | Procede pour la preparation de derives polyeniques |
| US4153615A (en) * | 1978-03-27 | 1979-05-08 | Hoffmann-La Roche Inc. | Method of producing coloring agents |
| EP0100839B1 (de) * | 1982-07-16 | 1986-05-07 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Katalytische Hydrierung acetylenischer Phosphoniumsalze |
| DE3476381D1 (en) * | 1983-03-25 | 1989-03-02 | Hoffmann La Roche | Process for the preparation of pentadienol derivatives |
-
1988
- 1988-02-29 DK DK106388A patent/DK171297B1/da not_active IP Right Cessation
- 1988-03-04 US US07/164,304 patent/US4952716A/en not_active Expired - Fee Related
- 1988-03-19 EP EP88104437A patent/EP0283979B1/de not_active Expired - Lifetime
- 1988-03-19 DE DE8888104437T patent/DE3874378D1/de not_active Expired - Lifetime
- 1988-03-19 AT AT88104437T patent/ATE80385T1/de not_active IP Right Cessation
- 1988-03-25 JP JP63069914A patent/JP2542667B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0283979A2 (de) | 1988-09-28 |
| DE3874378D1 (en) | 1992-10-15 |
| EP0283979A3 (en) | 1988-12-07 |
| DK171297B1 (da) | 1996-08-26 |
| JP2542667B2 (ja) | 1996-10-09 |
| ATE80385T1 (de) | 1992-09-15 |
| DK106388D0 (da) | 1988-02-29 |
| US4952716A (en) | 1990-08-28 |
| JPS63264565A (ja) | 1988-11-01 |
| EP0283979B1 (de) | 1992-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| AHB | Application shelved due to non-payment | ||
| PBP | Patent lapsed |