DK1067941T3 - Antitumorpræparat indeholdende en synergistisk kombination af et anthracyclinderivat og et camptothecinderivat - Google Patents

Antitumorpræparat indeholdende en synergistisk kombination af et anthracyclinderivat og et camptothecinderivat

Info

Publication number: DK1067941T3
Authority: DK; Denmark
Prior art keywords: derivative; preparation containing; synergistic combination; anthracycline; tumor preparation
Prior art date: 1998-03-24

Application number

DK99914528T

Other languages

Danish (da)

English (en)

Inventor

Cristina Geroni

Marina Ripamonti

Michele Caruso

Antonino Suarato

Original Assignee

Pharmacia Italia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-24

Filing date

1999-03-19

Publication date

2004-11-29

1999-03-19 Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa

2004-11-29 Application granted granted Critical

2004-11-29 Publication of DK1067941T3 publication Critical patent/DK1067941T3/da

Links

229940045799 anthracyclines and related substance Drugs 0.000 title 1
230000000259 anti-tumor effect Effects 0.000 title 1
VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
239000011885 synergistic combination Substances 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK99914528T 1998-03-24 1999-03-19 Antitumorpræparat indeholdende en synergistisk kombination af et anthracyclinderivat og et camptothecinderivat DK1067941T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9806324.1A GB9806324D0 (en)	1998-03-24	1998-03-24	Antitumour synergetic composition
EP99914528A EP1067941B1 (en)	1998-03-24	1999-03-19	Antitumor composition containing a synergistic combination of an anthracycline derivative with a camptothecin derivate

Publications (1)

Publication Number	Publication Date
DK1067941T3 true DK1067941T3 (da)	2004-11-29

Family

ID=10829188

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK99914528T DK1067941T3 (da)	1998-03-24	1999-03-19	Antitumorpræparat indeholdende en synergistisk kombination af et anthracyclinderivat og et camptothecinderivat

Country Status (29)

Country	Link
US (1)	US6403563B1 (cs)
EP (1)	EP1067941B1 (cs)
JP (1)	JP2002507571A (cs)
KR (1)	KR20010034619A (cs)
CN (2)	CN1150002C (cs)
AR (1)	AR018166A1 (cs)
AT (1)	ATE271388T1 (cs)
AU (1)	AU758191B2 (cs)
BR (1)	BR9908391A (cs)
CA (1)	CA2324610A1 (cs)
CZ (1)	CZ295368B6 (cs)
DE (1)	DE69918819T2 (cs)
DK (1)	DK1067941T3 (cs)
EA (1)	EA003134B1 (cs)
ES (1)	ES2226366T3 (cs)
GB (1)	GB9806324D0 (cs)
HU (1)	HUP0101615A3 (cs)
ID (1)	ID26091A (cs)
IL (1)	IL138035A0 (cs)
MY (1)	MY133016A (cs)
NO (1)	NO20004703L (cs)
NZ (1)	NZ507570A (cs)
PL (1)	PL343098A1 (cs)
PT (1)	PT1067941E (cs)
SI (1)	SI1067941T1 (cs)
TW (1)	TW576740B (cs)
UA (1)	UA63000C2 (cs)
WO (1)	WO1999048503A1 (cs)
ZA (1)	ZA992255B (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6820065B1 (en) *	1998-03-18	2004-11-16	Ascom Hasler Mailing Systems Inc.	System and method for management of postage meter licenses
GB9904387D0 (en) *	1999-02-25	1999-04-21	Pharmacia & Upjohn Spa	Antitumour synergistic composition
GB9909925D0 (en)	1999-04-29	1999-06-30	Pharmacia & Upjohn Spa	Combined preparations comprising anthracycline derivatives
GB9916882D0 (en) *	1999-07-19	1999-09-22	Pharmacia & Upjohn Spa	Antitumor synergistic composition
GB9926843D0 (en) *	1999-11-12	2000-01-12	Pharmacia & Upjohn Spa	Lipid complex of alkycyclines
US6627614B1 (en) *	2002-06-05	2003-09-30	Super Gen, Inc.	Sequential therapy comprising a 20(S)-camptothecin and an anthracycline
EP1985286A1 (en) *	2007-04-24	2008-10-29	Biocompatibles UK Limited	Microspheres for treatment of brain tumours
US20090107925A1 (en) *	2007-10-31	2009-04-30	Chevron U.S.A. Inc.	Apparatus and process for treating an aqueous solution containing biological contaminants
US8349764B2 (en)	2007-10-31	2013-01-08	Molycorp Minerals, Llc	Composition for treating a fluid
US20110207760A1 (en) *	2010-02-23	2011-08-25	Valery Alakhov	Sn-38 compositions
EP3327148B1 (en)	2010-06-18	2021-03-17	Myriad Genetics, Inc.	Methods of predicting the status of brca1 and brca2 genes in a cancer cell
ES2704303T3 (es)	2010-08-24	2019-03-15	Dana Farber Cancer Inst Inc	Procedimientos para la predicción de una respuesta contra el cáncer
US9233863B2 (en)	2011-04-13	2016-01-12	Molycorp Minerals, Llc	Rare earth removal of hydrated and hydroxyl species
ES2768344T3 (es)	2011-06-17	2020-06-22	Myriad Genetics Inc	Métodos y materiales para evaluar el desequilibrio alélico
JP6325453B2 (ja)	2011-12-21	2018-05-16	ミリアド・ジェネティックス・インコーポレイテッド	ヘテロ接合性の消失（ｌｏｓｓｏｆｈｅｔｅｒｏｚｙｇｏｓｉｔｙ）を評価するための方法および材料
ES2687024T3 (es)	2012-02-23	2018-10-23	Children's Medical Center Corporation	Procedimientos para predecir la respuesta contra el cáncer
CA2867434C (en)	2012-06-07	2021-10-12	Institut Curie	Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
US10308986B2 (en)	2013-03-14	2019-06-04	Children's Medical Center Corporation	Cancer diagnosis, treatment selection and treatment
DK2981624T3 (da)	2013-04-05	2020-03-02	Myriad Genetics Inc	Fremgangsmåder til vurdering af homolog rekombinationsdeficiens og forudsigelse af respons på cancerbehandling
CA2931181C (en)	2013-12-09	2023-01-24	Institut Curie	Methods for detecting inactivation of the homologous recombination pathway (brca1/2) in human tumors
MX370462B (es)	2014-03-07	2019-12-13	Secure Natural Resources Llc	Oxido de cerio (iv) con propiedades de remocion de arsenico excepcionales.
DK3686288T3 (da)	2014-08-15	2023-05-22	Myriad Genetics Inc	Fremgangsmåder og materialer til analyse af homolog rekombinationsdeficiens
EP4141127B1 (en)	2021-08-30	2024-10-09	Zentrum Familiärer Brust- und Eierstockkrebs Universitätsklinik Köln	Method for assessing homologous recombination deficiency in ovarian cancer cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9114549D0 (en) *	1991-07-05	1991-08-21	Erba Carlo Spa	Mono and bis alkylamino-anthracyclines
GB9325417D0 (en) *	1993-12-13	1994-02-16	Erba Carlo Spa	3'- aziridino-anthracycline derivatives

1998
- 1998-03-24 GB GBGB9806324.1A patent/GB9806324D0/en not_active Ceased
1999
- 1999-02-25 TW TW088102834A patent/TW576740B/zh not_active IP Right Cessation
- 1999-03-19 AU AU33314/99A patent/AU758191B2/en not_active Ceased
- 1999-03-19 EA EA200000978A patent/EA003134B1/ru not_active IP Right Cessation
- 1999-03-19 PL PL99343098A patent/PL343098A1/xx unknown
- 1999-03-19 CZ CZ20003493A patent/CZ295368B6/cs not_active IP Right Cessation
- 1999-03-19 NZ NZ507570A patent/NZ507570A/xx unknown
- 1999-03-19 SI SI9930675T patent/SI1067941T1/xx unknown
- 1999-03-19 UA UA2000105982A patent/UA63000C2/uk unknown
- 1999-03-19 KR KR1020007010503A patent/KR20010034619A/ko not_active Ceased
- 1999-03-19 CN CNB998043141A patent/CN1150002C/zh not_active Expired - Fee Related
- 1999-03-19 DE DE69918819T patent/DE69918819T2/de not_active Expired - Fee Related
- 1999-03-19 EP EP99914528A patent/EP1067941B1/en not_active Expired - Lifetime
- 1999-03-19 IL IL13803599A patent/IL138035A0/xx unknown
- 1999-03-19 AT AT99914528T patent/ATE271388T1/de not_active IP Right Cessation
- 1999-03-19 DK DK99914528T patent/DK1067941T3/da active
- 1999-03-19 PT PT99914528T patent/PT1067941E/pt unknown
- 1999-03-19 HU HU0101615A patent/HUP0101615A3/hu unknown
- 1999-03-19 CA CA002324610A patent/CA2324610A1/en not_active Abandoned
- 1999-03-19 CN CNA2004100317041A patent/CN1528334A/zh active Pending
- 1999-03-19 WO PCT/EP1999/001897 patent/WO1999048503A1/en not_active Ceased
- 1999-03-19 ES ES99914528T patent/ES2226366T3/es not_active Expired - Lifetime
- 1999-03-19 BR BR9908391-4A patent/BR9908391A/pt not_active IP Right Cessation
- 1999-03-19 US US09/646,096 patent/US6403563B1/en not_active Expired - Fee Related
- 1999-03-19 JP JP2000537551A patent/JP2002507571A/ja not_active Withdrawn
- 1999-03-19 ID IDW20001882A patent/ID26091A/id unknown
- 1999-03-22 MY MYPI99001071A patent/MY133016A/en unknown
- 1999-03-22 AR ARP990101246A patent/AR018166A1/es unknown
- 1999-03-23 ZA ZA9902255A patent/ZA992255B/xx unknown
2000
- 2000-09-20 NO NO20004703A patent/NO20004703L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
SI1067941T1 (en)	2005-02-28
EP1067941B1 (en)	2004-07-21
TW576740B (en)	2004-02-21
HUP0101615A3 (en)	2002-12-28
IL138035A0 (en)	2001-10-31
CA2324610A1 (en)	1999-09-30
NZ507570A (en)	2003-01-31
CN1294516A (zh)	2001-05-09
ZA992255B (en)	1999-10-05
DE69918819D1 (de)	2004-08-26
CZ20003493A3 (cs)	2001-02-14
AR018166A1 (es)	2001-10-31
JP2002507571A (ja)	2002-03-12
BR9908391A (pt)	2000-10-31
NO20004703D0 (no)	2000-09-20
EA200000978A1 (ru)	2001-02-26
GB9806324D0 (en)	1998-05-20
CN1528334A (zh)	2004-09-15
MY133016A (en)	2007-10-31
KR20010034619A (ko)	2001-04-25
PL343098A1 (en)	2001-07-30
CN1150002C (zh)	2004-05-19
PT1067941E (pt)	2004-12-31
US6403563B1 (en)	2002-06-11
EA003134B1 (ru)	2003-02-27
WO1999048503A1 (en)	1999-09-30
AU3331499A (en)	1999-10-18
CZ295368B6 (cs)	2005-07-13
NO20004703L (no)	2000-09-20
DE69918819T2 (de)	2005-08-18
ID26091A (id)	2000-11-23
AU758191B2 (en)	2003-03-20
HUP0101615A2 (hu)	2001-10-28
ES2226366T3 (es)	2005-03-16
UA63000C2 (en)	2004-01-15
EP1067941A1 (en)	2001-01-17
ATE271388T1 (de)	2004-08-15

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NO20004703L (no)	2000-09-20	Antitumor-sammensetning som inneholder en synergistisk kombinasjon av et antracyklinderivat med et camptothecinderivat
FI965248A0 (fi)	1996-12-30	Kehikkorungon ja jalustan käsittävä kytkinkaappi
DK0781086T3 (da)	1999-12-13	Præparering af frø
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NO305804B1 (no)	1999-07-26	Krystallinsk maltitolblanding og fremstilling derav
FI961915A7 (fi)	1996-05-06	Antrasykliinijohdannaiset
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NO970059D0 (no)	1997-01-08	Antrasyklinforbindelse og framgangsmåte for framstilling derav
NO982030D0 (no)	1998-05-05	1-arylsulfonyl-, arylkarbonyl- og aryltiokarbonylpyridazinoderivater og fremstilling derav
FI103937B1 (fi)	1999-10-29	Suorakylvömenetelmä ja suorakylvölaite
IL127135A (en)	2000-12-06	((Substituted alkoxy)-7-alkyl camptothecin) derivatives and their preparation
IL131372A (en)	2001-03-19	((Substituted alkoxy)-7-alkyl camptothecin) derivatives and their preparation
IT1284503B1 (it)	1998-05-21	Derivati tetraciclici spiro-condensati